CN203899622U - Micro-fluidic chip - Google Patents
Micro-fluidic chip Download PDFInfo
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- CN203899622U CN203899622U CN201420329586.1U CN201420329586U CN203899622U CN 203899622 U CN203899622 U CN 203899622U CN 201420329586 U CN201420329586 U CN 201420329586U CN 203899622 U CN203899622 U CN 203899622U
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Abstract
The utility model discloses a micro-fluidic chip. The micro-fluidic chip comprises a sample feeding hole, a sample feeding tank, detection tanks, fluid control valves and air outlet holes, wherein the sample feeding hole is formed in the sample feeding tank; the sample feeding tank is communicated with at least one detection tank through micro-fluidic channels; the other end of each detection tank is communicated with at least one air outlet hole; at least one fluid control valve is arranged between each detection tank and each air outlet hole; the volume of the sample feeding tank is not less than the sum of the capacities of the detection tanks. According to the micro-fluidic chip, the requirements on range of input pressure and change precision are low. Precise externally-connected control equipment is not needed and the aim that experiment liquid does not overflow can be realized only if external input pressure is lower than control pressure of valve bodies. With the adoption of the micro-fluidic chip, the liquid is controlled not to overflow and the stability of a reaction in the chip can be guaranteed; the accuracy and the stability of a quantitative test are ensured.
Description
Technical field
The utility model relates to a kind of micro-fluidic chip, belongs to micro-fluidic chip technical field.
Background technology
Micro-fluidic chip is formed network on chip by microchannel, run through whole system and complete a kind of technology of various biological and chemical processes with controlled microfluid.Owing to possessing the advantages such as low consumption, easy of integration, high flux and analysis speed be fast, micro-fluidic chip has been widely used in the fields such as chemistry, biology, medical science, and has started to start progressively to develop to Commercialization application from the laboratory research stage.
At present, common micro-fluidic chip fluid type of drive mainly contains: driven by power, pressure-driven.Wherein pressure-driven can be divided into again manual actuation and automatically drive.
Manual actuation is to be controlled by experimenter, and substep operation, manually completes fluid control.This class type of drive is simpler and cruder, and is difficult to realize automation and works continuously.Simultaneously, because the design of manual actuation mostly at present is: negative pressure etc. is inhaled in liquid storage tank static pressure poor (comprising vertical gravity drop), Entry Interface bilateral osmotic pressure, outlet, cause the processing and fabricating of micro-fluidic chip to be had relatively high expectations, be difficult to realize cheap, suitability for industrialized production.
Automatically drive and need a set of special pressure regulator for adjustable pressure.Owing to need to the variation of pressure accurately being controlled, cause these equipment often more complicated, volume is large, and manufacturing cost is high, energy consumption is high, can not be with easy reliable working method, cheap manufacturing cost, meets the microanalysis requirement of various site environments.
In recent years along with the application of micro-fluidic chip in POCT (Point-of-Care Testing, scene is detected immediately) technology is growing, people grow with each passing day for the demand of miniaturization, the micro-fluidic device that integrated, automaticity is higher.For realizing above-mentioned functions, for fluid control technology, people not only wish that it is simple in structure, easily integrated, and wish that outside associate device is also as much as possible small-sized and easy.
Utility model content
The purpose of this utility model is to provide a kind of micro-fluidic chip, and it is simple in structure, easily realizes cheap suitability for industrialized production, and can reduce the requirement to outside associate device.
Micro-fluidic chip provided by the utility model, comprises well, sample inlet pool, detection cell, control valve for fluids and venthole;
Described well is located on described sample inlet pool;
Described sample inlet pool is connected with detection cell described at least one by microfluid passage;
The other end of described detection cell is connected with venthole described at least one, and between described detection cell and described venthole, is provided with control valve for fluids described at least one;
The volume of described sample inlet pool is not less than the volume sum of described detection cell.
In above-mentioned micro-fluidic chip, described sample inlet pool is connected with multiple described detection cells, and multiple described detection cell is connected with a described venthole.
In above-mentioned micro-fluidic chip, between described detection cell and described venthole, be provided with a described control valve for fluids.
In above-mentioned micro-fluidic chip, between described detection cell and described venthole, be provided with multiple described control valves for fluids, and the quantity of described control valve for fluids and the quantity of described detection cell equate.
In above-mentioned micro-fluidic chip, described sample inlet pool is connected with multiple described detection cells, and multiple described detection cell is connected with multiple described ventholes, and the quantity of described detection cell equates with the quantity of described venthole.
In above-mentioned micro-fluidic chip, described sample inlet pool is connected with a described detection cell.
In above-mentioned micro-fluidic chip, on described sample inlet pool, be also provided with an air admission hole.
In above-mentioned micro-fluidic chip, described micro-fluidic chip comprises chip layer and cover plate layer, and described sample inlet pool, described detection cell and described control valve for fluids are located in described chip layer;
Described well, described venthole and described air admission hole are located on described cover plate layer.
In above-mentioned micro-fluidic chip, described control valve for fluids is structural drag valve.
In above-mentioned micro-fluidic chip, described structural drag valve comprises the control flume of being located on described micro-fluidic chip, described control flume is located in described microfluid passage, and coordinates for intersecting with described microfluid passage, and the two ends of stating microfluid passage are connected with pressurization hole and relief hole respectively;
Between described microfluid passage and described control flume, there is difference in height.
In above-mentioned micro-fluidic chip, the angle between described microfluid passage and described control flume is 0 °～180 °, but is not equal to 0 ° or 180 °.
In above-mentioned micro-fluidic chip, described control flume is groove or tongue.
In above-mentioned micro-fluidic chip, the difference in height between described microfluid passage and described control flume is at least 0.05mm.
In above-mentioned micro-fluidic chip, described microfluid passage is provided with one or more described control flumes.
In above-mentioned micro-fluidic chip, the height of described control flume is 0mm～10mm, but originally equals zero;
The width of described control flume is 0mm～100mm, but is not equal to zero;
The length of described control flume is 0mm～100mm, but is not equal to zero.
Micro-fluidic chip of the present utility model can be formed by materials processings such as polyethylene, Merlon, polymethyl methacrylate, dimethyl silicone polymer, polypropylene, glass or quartz.
In the detection cell of the utility model micro-fluidic chip, can pre-fix enzyme that biological detection uses, antibody, primer etc., detect for carrying out the projects such as biochemistry, immunity, nucleic acid.
The utility model micro-fluidic chip tool has the following advantages:
The utility model micro-fluidic chip simple in structure, and can carry out single injection-molded, requires lowly to mould, realize cheap industrialized mass production.Use when the utility model, without by the control that outreaches facility switching is reached to the object that liquid does not overflow.Scope and the variation required precision of the utility model micro-fluidic chip to input pressure is low.Without the control appliance that outreaches of precision, only need extraneous input pressure to be less than the object that valve body controlled pressure just can experimental liquid overflow.The utility model micro-fluidic chip reaches control liquid and does not overflow, and can ensure the stable of the interior reaction of chip, ensures accuracy and the stability of quantitative test.The utility model micro-fluidic chip can meet single sample sample introduction, and entry porous detects simultaneously, ensures that various liquid does not all overflow, and meets the object of porous quantitative test simultaneously.
Brief description of the drawings
The structural representation of the micro-fluidic chip that Fig. 1 provides for the embodiment of the present invention 1, the top view that Fig. 1 (a) is this chip, Fig. 1 (b) is this chip stereo structural representation.
The structural representation of the micro-fluidic chip that Fig. 2 provides for the embodiment of the present invention 2.
The structural representation of the micro-fluidic chip that Fig. 3 provides for the embodiment of the present invention 3.
The structural representation of the micro-fluidic chip that Fig. 4 provides for the embodiment of the present invention 4.
The structural representation of the micro-fluidic chip that Fig. 5 provides for the embodiment of the present invention 5.
The structural representation of the micro-fluidic chip that Fig. 6 provides for the embodiment of the present invention 6, the top view that Fig. 6 (a) is this chip, Fig. 6 (b) and Fig. 6 (c) they are this chip stereo structural representation.
Fig. 7 is the structural representation of control valve for fluids in micro-fluidic chip of the present invention, and Fig. 7 (a) is top view, and Fig. 7 (b) is sectional view.
In figure, each mark is as follows:
1 sample inlet pool, 2 wells, 3 microfluid passage, 4 detection cells, 5 control valves for fluids, 6 ventholes, 7 air admission holes, 8 chip layer, 9 cover plate layers, 10 control flumes.
Detailed description of the invention
Below in conjunction with accompanying drawing, the utility model is described further, but the utility model is not limited to following examples.
Embodiment 1,
The micro-fluidic chip top view that the present embodiment provides is as shown in Fig. 1 (a), this chip comprises well 2, sample inlet pool 1, detection cell 4, control valve for fluids 5 and venthole 6 and microfluid passage 3, its three-dimensional composition is as shown in Fig. 1 (b), formed by chip layer 8 and cover plate layer 9, sample inlet pool 1, detection cell 4, control valve for fluids 5 and microfluid passage 3 are distributed in chip layer 8, and well 2 and venthole 6 are distributed in cover plate layer 9.Well 2 is located on sample inlet pool 1, and sample inlet pool 1 is connected with 4 detection cells 4 by 4 microfluid passage 3; These 4 detection cells 4 are connected with a venthole 6, and are provided with a control valve for fluids 5 between detection cell 4 and venthole 6; The volume of sample inlet pool 1 is not less than the volume sum of 4 detection cells 4.
The top view of the control valve for fluids 5 in the present embodiment is as shown in Fig. 7 (a), and this microfluidic control valve 5 is for being located at 3 control flumes 10 in microfluid passage 3, and microfluid passage 3 in 90 ° angle setting crossing with control flume 10, vertically arranges.The two ends of microfluid passage 3 are communicated with respectively pressurization hole and relief hole.The width of microfluid passage 3 is 1mm; The width of control flume 10 is 1mm.
The sectional view of the microfluidic control valve that the present embodiment provides is as shown in Fig. 7 (b), and the height of microfluid passage 3 is 0.5mm, and the height of control flume 10 is 1mm.This microfluidic control valve can stop the pressure of the highest 100mmHg, ensures that liquid does not spill.
Use procedure is as follows: sample is injected after chip by well 1, temporarily be stored in sample inlet pool 1, well 2 connects air pump, promote to flow along microfluid passage 3 by air pump pressure, enter in detection cell 4, with the reagent reacting pre-fixing in detection cell 4, sample is stopped by control valve for fluids 5 simultaneously, when air pump pressure is less than control valve for fluids 5 resistance, liquid does not overflow from venthole 6.
Embodiment 2,
As shown in Figure 2, this chip comprises well 2, sample inlet pool 1, detection cell 4, control valve for fluids 5, venthole 6 and microfluid passage 3 to the micro-fluidic chip top view that the present embodiment provides.Well 2 is located on sample inlet pool 1, and sample inlet pool 1 is connected with 4 detection cells 4 by 4 microfluid passage 3; These 4 detection cells 4 are connected with 4 ventholes 6, and are provided with a control valve for fluids 5 between each detection cell 4 and each venthole 6; The volume of sample inlet pool 1 is not less than the volume sum of 4 detection cells 4.
The top view of the control valve for fluids 5 in the present embodiment is as shown in Fig. 7 (a), and sectional view is as shown in Fig. 7 (b).
Use procedure is as follows: sample is injected after chip by well 1, temporarily be stored in sample inlet pool 1, well 2 connects air pump, promote to flow along microfluid passage 3 by air pump pressure, enter in detection cell 4, with the reagent reacting pre-fixing in detection cell 4, sample is stopped by the control valve for fluids 5 being connected with each detection cell 4 simultaneously, when air pump pressure is less than control valve for fluids 5 resistance, liquid does not overflow from venthole 6.
Embodiment 3,
As shown in Figure 3, this chip comprises well 2, sample inlet pool 1, detection cell 4, control valve for fluids 5, venthole 6 and microfluid passage 3 to the micro-fluidic chip top view that the present embodiment provides.Well 2 is located on sample inlet pool 1, and sample inlet pool 1 is connected with 4 detection cells 4 by 4 microfluid passage 3; These 4 detection cells 4 are connected with a venthole 6, and are equipped with a control valve for fluids 5 between each detection cell 4 and venthole 6; The volume of sample inlet pool 1 is not less than the volume sum of 4 detection cells 4.
The top view of the control valve for fluids 5 in the present embodiment is as shown in Fig. 7 (a), and sectional view is as shown in Fig. 7 (b).
Use procedure is as follows: sample is injected after chip by well 2, temporarily be stored in sample inlet pool 1, well 1 connects air pump, promote to flow along microfluid passage 3 by air pump pressure, enter in detection cell 4, with the reagent reacting pre-fixing in detection cell 4, sample is stopped by the control valve for fluids 5 being connected with each detection cell 4 simultaneously, when air pump pressure is less than control valve for fluids 5 resistance, liquid does not overflow from the venthole 6 being connected with multiple control valves for fluids 5.
Embodiment 4,
As shown in Figure 4, this chip comprises well 2, air admission hole 7, sample inlet pool 1, detection cell 4, control valve for fluids 5, venthole 6 and microfluid passage 3 to the micro-fluidic chip top view that the present embodiment provides.Well 2 and air admission hole 7 are all located on sample inlet pool 1, and sample inlet pool 1 is connected with 1 detection cell 4 by 1 microfluid passage 3; This detection cell 4 is connected with a venthole 6, and is provided with a control valve for fluids 5 between detection cell 4 and venthole 6; The volume of sample inlet pool 1 is not less than the volume of detection cell 4.
The top view of the control valve for fluids 5 in the present embodiment is as shown in Fig. 7 (a), and sectional view is as shown in Fig. 7 (b).
Use procedure is as follows: sample is injected after chip by well 2, temporarily be stored in sample inlet pool 1, air admission hole 7 connects air pump, promote to flow along microfluid passage 3 by air pump pressure, enter in detection cell 4, with the reagent reacting pre-fixing in detection cell 4, sample is stopped by the control valve for fluids 5 being connected with detection cell 4 simultaneously, when air pump pressure is less than control valve for fluids 5 resistance, liquid does not overflow from venthole 6.
Embodiment 5,
As shown in Figure 4, this chip comprises well 2, sample inlet pool 1, detection cell 4, control valve for fluids 5, venthole 6 and microfluid passage 3 to the micro-fluidic chip top view that the present embodiment provides.Well 2 is located on sample inlet pool 1, and sample inlet pool 1 is connected with 1 detection cell 4 by 1 microfluid passage 3; This detection cell 4 is connected with a venthole 6, and is provided with a control valve for fluids 5 between detection cell 4 and venthole 6; The volume of sample inlet pool 1 is not less than the volume of detection cell 4.
The top view of the control valve for fluids 5 in the present embodiment is as shown in Fig. 7 (a), and sectional view is as shown in Fig. 7 (b).
Use procedure is as follows: sample is injected after chip by well 2, temporarily be stored in sample inlet pool 1, well 2 connects air pump, promote to flow along microfluid passage 3 by air pump pressure, enter in detection cell 4, with the reagent reacting pre-fixing in detection cell 4, sample is stopped by the control valve for fluids 5 being connected with detection cell 4 simultaneously, when air pump pressure is less than control valve for fluids 5 resistance, liquid does not overflow from venthole 6.
Embodiment 6,
The micro-fluidic chip top view that the present embodiment provides is as shown in Fig. 6 (a), and this chip is by well 2, sample inlet pool 1, detection cell 4, control valve for fluids 5, venthole 6 and microfluid passage 3; Its three-dimensional composition, as shown in Fig. 6 (b), (c), is made up of chip layer 8, cover plate layer 9, and sample inlet pool 1, detection cell 4 and microfluid passage 3 are distributed in chip layer 8, and well 2, venthole 6 and control valve for fluids 5 are distributed in cover plate layer 9.Well 2 is located on sample inlet pool 1, and sample inlet pool 1 is connected with 1 detection cell 4 by 1 microfluid passage 3; This detection cell 4 is connected with a venthole 6, and is provided with a control valve for fluids 5 between detection cell 4 and venthole 6; The volume of sample inlet pool 1 is not less than the volume of detection cell 4.
The top view of the control valve for fluids 5 in the present embodiment is as shown in Fig. 7 (a), and sectional view is as shown in Fig. 7 (b).
Use procedure is as follows: sample is injected after chip by well 2, temporarily be stored in sample inlet pool 1, well 2 connects air pump, promote to flow along microfluid passage 3 by air pump pressure, enter detection cell 4, with the reagent reacting pre-fixing in detection cell 4, sample is stopped by control valve for fluids 5 simultaneously, when air pump pressure is less than control valve for fluids 5 resistance, liquid does not overflow from venthole 6.
Claims (10)
1. a micro-fluidic chip, is characterized in that: it comprises well, sample inlet pool, detection cell, control valve for fluids and venthole;
Described well is located on described sample inlet pool;
Described sample inlet pool is connected with detection cell described at least one by microfluid passage;
The other end of described detection cell is connected with venthole described at least one, and between described detection cell and described venthole, is provided with control valve for fluids described at least one;
The volume of described sample inlet pool is not less than the volume sum of described detection cell.
2. micro-fluidic chip according to claim 1, is characterized in that: described sample inlet pool is connected with multiple described detection cells, and multiple described detection cell is connected with a described venthole.
3. micro-fluidic chip according to claim 2, is characterized in that: between described detection cell and described venthole, be provided with a described control valve for fluids.
4. micro-fluidic chip according to claim 2, is characterized in that: between described detection cell and described venthole, be provided with multiple described control valves for fluids, and the quantity of described control valve for fluids and the quantity of described detection cell equate.
5. micro-fluidic chip according to claim 1, is characterized in that: described sample inlet pool is connected with multiple described detection cells, and multiple described detection cell is connected with multiple described ventholes, and the quantity of described detection cell equates with the quantity of described venthole.
6. micro-fluidic chip according to claim 1, is characterized in that: described sample inlet pool is connected with a described detection cell.
7. according to the micro-fluidic chip described in any one in claim 1-6, it is characterized in that: on described sample inlet pool, be also provided with an air admission hole.
8. micro-fluidic chip according to claim 7, is characterized in that: described micro-fluidic chip comprises chip layer and cover plate layer, and described sample inlet pool, described detection cell and described control valve for fluids are located in described chip layer;
Described well, described venthole and described air admission hole are located on described cover plate layer.
9. micro-fluidic chip according to claim 8, is characterized in that: described control valve for fluids is structural drag valve.
10. micro-fluidic chip according to claim 8, it is characterized in that: described structural drag valve comprises the control flume of being located on described micro-fluidic chip, described control flume is located in described microfluid passage, and coordinate for intersecting with described microfluid passage, the two ends of described microfluid passage are connected with pressurization hole and relief hole respectively;
Between described microfluid passage and described control flume, there is difference in height.
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| CN201420329586.1U CN203899622U (en) | 2014-06-19 | 2014-06-19 | Micro-fluidic chip |
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Cited By (15)
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| CN105032511A (en) * | 2015-08-25 | 2015-11-11 | 辽宁中医药大学 | Micro-fluidic chip capable of generating stable concentration gradient in controlled manner |
| CN105344388A (en) * | 2015-09-24 | 2016-02-24 | 杭州师范大学 | Micro-fluidic chip |
| CN105483293A (en) * | 2016-01-29 | 2016-04-13 | 中国人民解放军疾病预防控制所 | Fulminating-infectious-disease pathogen detecting primer pair and kit |
| CN106563517A (en) * | 2016-10-26 | 2017-04-19 | 杭州霆科生物科技有限公司 | Micro-fluidic chip and detection system for detecting formaldehyde and pH value of textile |
| CN106902905A (en) * | 2017-04-01 | 2017-06-30 | 苏州岚轩生物科技有限公司 | Back-flow preventer and its micro-fluidic chip are controlled for micro-fluidic chip liquid |
| CN107629951A (en) * | 2017-09-29 | 2018-01-26 | 深圳国际旅行卫生保健中心 | Micro-fluidic gene detecting chip |
| CN108435266A (en) * | 2018-04-11 | 2018-08-24 | 上海速创诊断产品有限公司 | A kind of micro-fluidic detection chip and the kit based on it, whole blood multiple determination methods and applications |
| CN108745429A (en) * | 2018-06-12 | 2018-11-06 | 南京岚煜生物科技有限公司 | A kind of multichannel quickly detects microfluid detection chip |
| CN108795732A (en) * | 2017-04-27 | 2018-11-13 | 京东方科技集团股份有限公司 | A kind of gene detecting chip, its detection method and micro-fluidic chip system |
| CN108855264A (en) * | 2018-07-12 | 2018-11-23 | 北京乐普智慧医疗科技有限公司 | A kind of multipurpose multi objective micro-fluidic chip |
| WO2019006977A1 (en) | 2017-07-03 | 2019-01-10 | 南京岚煜生物科技有限公司 | Multiflux microfluidic chip based on active control on liquid flowing |
| WO2019006978A1 (en) | 2017-07-03 | 2019-01-10 | 南京岚煜生物科技有限公司 | Single-channel chemiluminescence microfluidic chip and detection method thereof |
| CN111929460A (en) * | 2020-08-19 | 2020-11-13 | 河南科技大学 | Sampling, chip and liquid inlet control device suitable for microfluidic automatic detection |
| CN113634294A (en) * | 2021-08-27 | 2021-11-12 | 江苏溢康辰医疗科技有限公司 | Active bidirectional microfluidic structure and application method thereof |
| CN113866158A (en) * | 2021-08-30 | 2021-12-31 | 上海睿钰生物科技有限公司 | Particle detection device and operation method thereof |
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- 2014-06-19 CN CN201420329586.1U patent/CN203899622U/en active Active
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105032511A (en) * | 2015-08-25 | 2015-11-11 | 辽宁中医药大学 | Micro-fluidic chip capable of generating stable concentration gradient in controlled manner |
| CN105344388A (en) * | 2015-09-24 | 2016-02-24 | 杭州师范大学 | Micro-fluidic chip |
| CN105483293A (en) * | 2016-01-29 | 2016-04-13 | 中国人民解放军疾病预防控制所 | Fulminating-infectious-disease pathogen detecting primer pair and kit |
| CN105483293B (en) * | 2016-01-29 | 2019-07-16 | 中国人民解放军疾病预防控制所 | Deadly infectious disease pathogen detection primer sets and kit |
| CN106563517A (en) * | 2016-10-26 | 2017-04-19 | 杭州霆科生物科技有限公司 | Micro-fluidic chip and detection system for detecting formaldehyde and pH value of textile |
| CN106902905A (en) * | 2017-04-01 | 2017-06-30 | 苏州岚轩生物科技有限公司 | Back-flow preventer and its micro-fluidic chip are controlled for micro-fluidic chip liquid |
| CN108795732A (en) * | 2017-04-27 | 2018-11-13 | 京东方科技集团股份有限公司 | A kind of gene detecting chip, its detection method and micro-fluidic chip system |
| WO2019006977A1 (en) | 2017-07-03 | 2019-01-10 | 南京岚煜生物科技有限公司 | Multiflux microfluidic chip based on active control on liquid flowing |
| US10761092B2 (en) | 2017-07-03 | 2020-09-01 | Lansion Biotechnology Co., Ltd. | Multi-flux micro-fluidic chip based on active fluid flow control |
| WO2019006978A1 (en) | 2017-07-03 | 2019-01-10 | 南京岚煜生物科技有限公司 | Single-channel chemiluminescence microfluidic chip and detection method thereof |
| CN107629951A (en) * | 2017-09-29 | 2018-01-26 | 深圳国际旅行卫生保健中心 | Micro-fluidic gene detecting chip |
| CN108435266A (en) * | 2018-04-11 | 2018-08-24 | 上海速创诊断产品有限公司 | A kind of micro-fluidic detection chip and the kit based on it, whole blood multiple determination methods and applications |
| CN108435266B (en) * | 2018-04-11 | 2021-01-08 | 上海速创诊断产品有限公司 | Microfluidic detection chip, kit based on microfluidic detection chip, whole blood multi-index detection method and application |
| CN108745429A (en) * | 2018-06-12 | 2018-11-06 | 南京岚煜生物科技有限公司 | A kind of multichannel quickly detects microfluid detection chip |
| CN108745429B (en) * | 2018-06-12 | 2023-11-24 | 南京岚煜生物科技有限公司 | Multichannel rapid detection microfluid detection chip |
| CN108855264A (en) * | 2018-07-12 | 2018-11-23 | 北京乐普智慧医疗科技有限公司 | A kind of multipurpose multi objective micro-fluidic chip |
| CN111929460A (en) * | 2020-08-19 | 2020-11-13 | 河南科技大学 | Sampling, chip and liquid inlet control device suitable for microfluidic automatic detection |
| CN111929460B (en) * | 2020-08-19 | 2024-03-01 | 河南科技大学 | Sampling, chip and liquid inlet control device suitable for microfluidic automatic detection |
| CN113634294A (en) * | 2021-08-27 | 2021-11-12 | 江苏溢康辰医疗科技有限公司 | Active bidirectional microfluidic structure and application method thereof |
| CN113866158A (en) * | 2021-08-30 | 2021-12-31 | 上海睿钰生物科技有限公司 | Particle detection device and operation method thereof |
| CN113866158B (en) * | 2021-08-30 | 2024-02-09 | 上海睿钰生物科技有限公司 | Particle detection device and operation method thereof |
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