CN203885613U - Radiofrequency ablation catheter and conveying system thereof - Google Patents

Radiofrequency ablation catheter and conveying system thereof Download PDF

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Publication number
CN203885613U
CN203885613U CN201420132897.9U CN201420132897U CN203885613U CN 203885613 U CN203885613 U CN 203885613U CN 201420132897 U CN201420132897 U CN 201420132897U CN 203885613 U CN203885613 U CN 203885613U
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China
Prior art keywords
conduit
profile section
electrode
function profile
conduit part
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CN201420132897.9U
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Chinese (zh)
Inventor
张钲
胡昌
陈艳
程增兵
谭家宏
孙毅勇
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Shanghai Hongdian Medical Technology Co ltd
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Shanghai Microport EP MedTech Co Ltd
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Abstract

The utility model provides a radiofrequency ablation catheter and a conveying system thereof. The catheter comprises a functional shape section catheter part and a main body section catheter part, wherein electrodes are arranged on the outer side of the functional shape section catheter part; moreover, the functional shape section catheter part can be switched between a basic state and a spreading state; in the basic state, the functional shape section catheter part bends, so that the electrodes cling to the blood vessel wall; in the spreading state, the functional shape section catheter part straightens so as to move in the blood vessel; the catheter is characterized in that the electrodes are covered on the catheter circumference of a side part closer to the blood vessel wall. According to the radiofrequency ablation catheter and the conveying system thereof, the area of blood flow in the blood vessel is decreased or the blood flow in the blood vessel is blocked, while the close clinging between the electrodes and the blood vessel is effectively increased for ablation to realize the purpose of thoroughly blocking the vascular adventitia sympathetic nerve fibers; therefore the functions of being safer and more effective are realized.

Description

Radio frequency ablation catheter and induction system thereof
Technical field
This utility model relates to a kind of medical apparatus and instruments for radio-frequency (RF) ablation.More specifically, this utility model relates to a kind of conduit for radio-frequency (RF) ablation, for in blood vessel, go sympathetic nerve radio-frequency (RF) ablation, as renal artery goes sympathetic nerve treatment intractable hypertension or ring pulmonary vein isolation to treat in atrial fibrillation, pulmonary artery, go sympathetic nerve radio-frequency (RF) ablation etc.This utility model also relates to the induction system of conduit.
Background technology
Hypertension has that sickness rate is high, awareness is low, endanger large feature.The hypertensive ill crowd of China surpasses 200,000,000 at present, wherein intractable hypertension (claiming again refractory hypertension) accounts for 15%, and this hypertension refers to and adopts life style improvement and 3 kinds or 3 kinds of hypertension that above antihypertensive drugs (comprising a kind of diuretic) treatment still can not effectively be controlled.And because Drug therapy can not make patient's reach mark blood pressure all the time, the incidence rate of patient's target organ damage (apoplexy, renal dysfunction and coronary heart disease) also obviously raises.
Experimental data shows that hypertension is higher relevant with patient's kidney sympathetic excitability.Blocking-up kidney sympathetic nerve not only can make blood pressure drops, and the chronic organ specificity disease that can cause sympathetic nerve excessive activation exerts an influence.In addition, blocking-up kidney sympathetic nerve can also improve left ventricular hypertrophy and insulin resistant.In recent years there is scholar to use ablation catheter, the sympathetic nerve on renal artery wall is carried out to radio-frequency (RF) ablation, to treat intractable hypertension.What adopt at present is that catheter ablation renal artery goes sympathetic nerve art (RDN), this is by carrying out catheter ablation at renal artery inner membrance, sympathetic fiber with damage along the domination kidney of tunica adventitia traveling, retardance spreads out of and centripetal fiber, thereby produces treatment effect.
At present, RDN is mainly used in treating intractable hypertension, and it also starts to be realized in the benefit of improving the aspects such as insulin resistant, treatment heart failure simultaneously.Congestive heart failure (CHF) is a kind of disease occurring when heart is damaged and arrives the blood flow minimizing of organ.If blood flow fully reduces, renal function is changed, and this causes fluid retention, not normal hormone secretion and the vasoconstriction of increase.These results have increased the workload of heart and have further reduced heart pump blood through the ability of kidney and blood circulation.
Yet, because going sympathetic nerve art, renal artery is different from common arrhythmia radio-frequency (RF) ablation, there is complexity and the particularity of self, and therefore need to carry out multiple spot ring-type to renal artery and ventral aorta oral area and melt and could thoroughly block adventitia sympathetic fiber.And, although renal artery blood vessel is less, by its conduction, still make kidney receive from heart more than 20% containing the total blood volume of oxygen.Therefore,, if block the blood flow of blood vessel in ablation procedure, will cause great damage to kidney.
Radio frequency ablation catheter for renal artery is to adopt the most key, the indispensable instrument of RDN treatment intractable hypertension, and wherein conduit enters renal artery and ventral aorta oral area melts through ventral aorta.At present conventional radio frequency ablation catheter for renal artery adopts single tip electrode, basket type is multipole or helical form is multipole design.These designs all have problem separately, while adopting single tip electrode vessel cover to complicated renal artery blood vessel, need patient to come reclining of control electrode and ablation locations by rotary handle, the effect that this increases operating difficulty and is difficult to reach thorough blocking-up adventitia sympathetic fiber; The multipole conduit of basket type is due to moulding process problem, and far-end is harder, has damage patient vessel's risk; Although the multipole conduit of helical form effectively reduces the operating difficulty that patient finds target spot, due to conduit diameter and ring electrode larger, there is the risk of blocking blood flow induced renal damage.And above-mentioned multipole conduit all adopts annular ring electrode, kind electrode is because the restriction of self shape cannot closely effectively recline with vascularization, conduit existed fail thoroughly to block the risk of adventitia sympathetic fiber.
In addition, domestic and international many clinical researches show also can application catheter radio-frequency ablation technique electricity isolation of pulmonary veins effectively to prevent the recurrence of atrial fibrillation (atrial fibrillation).Conduit for ring pulmonary vein isolation has much in the market, comprises cold brine perfusion conduit, multi-pole ring lung catheter etc.Yet, because the pulmonary vein electricity isolation of atrial fibrillation is different from common arrhythmia radio-frequency (RF) ablation case, there is complexity and the particularity of self, all there are some defects in above-mentioned conduit therefore when carrying out CAPV.Cold brine perfusion conduit is one pole conduit, and for guaranteeing blocking-up pulmonary vein sympathetic fiber, patient need to control conduit by continuous control handle and find target spot, and this increases patient's operation easier; Although multi-pole ring lung catheter can effectively reduce the operating difficulty that patient finds target spot, due to conduit diameter and ring electrode larger, there is the risk of blocking blood flow induced renal damage.And above-mentioned multipole conduit adopts annular ring electrode equally, kind electrode is because the restriction of self shape cannot closely effectively recline with vascularization, conduit existed fail thoroughly to block the risk of adventitia sympathetic fiber.
Experimental data also shows that pulmonary hypertension is higher relevant with Patients with Lung intra-arterial sympathetic excitability, and in blocking-up pulmonary artery, sympathetic nerve can make pulmonary artery pressure decline.But, lack at present professional operating theater instruments, particularly special-purpose pulmonary artery radio frequency ablation catheter.
Chinese invention patent application CN102274074A discloses a kind of Multi-electrode open-type radio frequency ablation catheter, and the one end at its electrode place is connected with catheter main body, and the other end is multipole open.But this multipole open conduit safety in entering renal artery blood vessel can not be guaranteed, and is not easy to control conduit way moving in renal artery.
International Patent Application WO 2011/060339A1 discloses a kind of quadrupole ablation catheter, and it can one-time positioning realize melting of four target spots.But for the renal artery vessel position of renal artery blood vessel mouth and labyrinth, this conduit can not be realized and melting.
Chinese invention patent application CN200610150659.0 discloses a kind of conduit with basket type electrode, for orifices of pulmonary veins, melts.But this conduit can not melt for renal artery, because the electrode of conduit is too fine and close, be very easy to cause renal artery stenosis.In addition, the projection of the centre of the electrode section of this conduit is excessive, can cause excessive damage to renal artery blood vessel.
International Patent Application WO/2007/003058 discloses a kind of ablation catheter that struts four electrodes with sacculus, and four electrodes of this conduit, in same plane, easily cause narrow while melting in renal artery.In addition, the sacculus strutting can block renal artery blood flow, and kidney is also had a certain impact.
U.S. Patent application US2013/0304062A1 discloses a kind of spiral duct, and the spiral section of this conduit can strut or lock by seal wire.But this conduit diameter is larger, while melting in renal artery, easily cause narrow.In addition, larger conduit is more prone to block the blood flow in renal artery, and kidney dis is being damaged to risk.
Therefore, exist for removing the needs of sympathetic nerve radio frequency ablation catheter in blood vessel.
Summary of the invention
This utility model is intended to solve current catheter ablation renal artery and goes sympathetic nerve art in order to treat intractable hypertension, ring pulmonary vein isolation art to treat atrial fibrillation, to go pulmonary artery sympathetic nerve art there is no the problem of safe and effective medical apparatus and instruments with Therapeutic Method such as treatment pulmonary hypertensions.For this reason, this utility model provides a kind of radio frequency ablation catheter, for going sympathetic nerve radio-frequency (RF) ablation in blood vessel, as renal artery goes sympathetic nerve treatment intractable hypertension or ring pulmonary vein isolation to treat in atrial fibrillation, pulmonary artery, goes sympathetic nerve radio-frequency (RF) ablation etc.
In first aspect, this utility model provides a kind of radio frequency ablation catheter, described conduit comprises function profile section conduit part and main paragraph conduit part, electrode is arranged on the outside of described function profile section conduit part, and described function profile section conduit part can be switched between ground state and deployed condition, wherein under ground state, function profile section conduit part is crooked, so that electrode note is by blood vessel wall, under deployed condition, function profile section conduit partly stretches to move in blood vessel, it is characterized in that, described electrode package is overlying on the conduit circumference of the nearly side part of blood vessel wall.
The electrode of conduit of the present utility model partly adopts the structure being coated on from the conduit circumference of the nearly side part of blood vessel wall, different from the electrode part of the closed-loop structure of conventional catheters, the electrode surface of this electrode is attached to function profile section conduit part and divides outside, and inner side does not have ring electrode.In this way, can reduce the axial area of electrode, thereby reach, reduce blood flow area in blocking-up blood vessel, reduce the risk of patient vessel, kidney injury.Therefore, this utility model, when effectively increasing electrode and blood vessel and closely reclining and melt to realize the object of thorough blocking-up tunica adventitia sympathetic fiber, reduces the interior blood flow area of blocking-up blood vessel, thereby reaches more safe and effective effect.
According to embodiment of the present utility model, function profile section conduit part is divided into spiral type or annular, preferably spiral type.
According to embodiment of the present utility model, in function profile section conduit part, be provided with vertically 4 or 6 electrodes.Preferably, electrodeplate is 4, observe vertically, and 90 ° of adjacent electrode each intervals, 4 electrodes are around axially forming a circle, 360 °.
According to embodiment of the present utility model, described function profile section conduit part can be by polyurethane, polyimides, polyetheramides, the materials such as polyamide are made, the tubing of can zone of preference metal knitted silk, tubing that also can the non-metal knitted silk of zone of preference, and the diameter of tubing is 0.5-4.0mm, length is 10.0-20.0mm, and preferably diameter is 1.667-3mm, length 25-30mm.
According to embodiment of the present utility model, described function profile section conduit part is also provided with salt water hole, in order to provide salt aquaporin to each electrode, to realize the cooling of tissue and electrode.Preferably, 4 salt water holes are set, the area in salt water hole is preferably the ratio of 9:7:4:3 to near-end by far-end.This is that the flow of saline can corresponding decline due to when saline passes through salt of the same area water hole.Experimental data shows, from far-end to near-end, the linkage in two adjacent far-end salt water holes and two adjacent near-end salt water holes is eager to excel in whatever one does compared with the linkage between all the other two holes, so reduce the water-outlet area in two salt water holes of near-end, increase the water-outlet area in two salt water holes of far-end simultaneously, can guarantee that brine flow is uniformly distributed.According to embodiment of the present utility model, the distal-most end of function profile section conduit part is 33-35mm apart from first electrode distance, and each electrode spacing is 7mm, to catheter perfusion 17ml/ minutes (approximately 28.3 * 10 -8mm 3/ s), during brine flow, the flow that can realize each salt water hole is roughly the same.
According to embodiment of the present utility model, main paragraph conduit part can be by polyurethane, polyimides, polyetheramides, the materials such as polyamide are made, the tubing of can zone of preference metal knitted silk, tubing that also can the non-metal knitted silk of zone of preference, and the diameter of tubing is 1.0-4.0mm, length is 450.0-1550.0mm, and preferably diameter is 1.667-2mm, length 700-900mm.
According to embodiment of the present utility model, described function profile section conduit partly adopts multi-lumen tube, for example three chambeies or four lumens, and four lumens preferably, and it has good compliance, guarantees that conduit can successfully enter renal artery blood vessel through renal artery ostium.The chamber of described multi-lumen tube comprises guidewire lumen, salt water cavity, guidewire lumen.Main paragraph conduit part also can adopt with function profile section conduit part divides identical multi-lumen tube.
According to embodiment of the present utility model, the material of electrode can be platinumiridio, rustless steel, gold, silver etc., preferably platinumiridio.Electrode package is overlying on the conduit circumference of the nearly side part of blood vessel wall, and bending radius is 3mm, 3.5mm or 4mm, and preferably bending radius is 3mm.Described catheter electrode adopts the structure being coated on from the conduit circumference of the nearly side part of blood vessel wall, and crooked radian partly the crooked radian under ground state is identical with function profile section conduit.In this way, increase electrode and the blood vessel degree of ablation that closely reclines, thereby realize, thoroughly block adventitia sympathetic fiber.Preferably, the surface of electrode is provided with hole for water spraying.
Preferably, described conduit also comprises and can curved segment conduit part divide, and it is between function profile section conduit part and main paragraph conduit part are divided.According to embodiment of the present utility model, describedly can curved segment conduit part divide employing multi-lumen tube, preferably adopt four lumens, there is good compliance, and equally can be by polyurethane, polyimides, polyetheramides, the materials such as polyamide are made.The chamber of described multi-lumen tube also comprises guidewire lumen, salt water cavity, guidewire lumen and bracing wire chamber, can curved segment conduit part in bracing wire chamber divides with bracing wire and for example by the bonding mode of glue, is connected as a single entity.In this way, tear bracing wire and can control the curved variation can curved segment conduit part dividing, thereby realize the curved object of conduit control.The tubing can curved segment conduit part dividing equally can the metal knitted silk of zone of preference tubing, tubing that also can the non-metal knitted silk of zone of preference, and pipe diameter is 1.667-4mm, length is 10-30mm, preferably, with the tubing of metal knitted silk, diameter is 1.667mm, and length is 25mm.
Preferably, the changeover portion between described that can curved segment conduit part divide and described function profile section conduit part is divided, bracing wire chamber and guidewire lumen can share a chamber, and this intracavity serves as a contrast smooth coating.
In second aspect, this utility model provides a kind of induction system of radio frequency ablation catheter, and it comprises above-mentioned conduit and control crank, and this control crank divides and is connected with the main paragraph conduit part of described conduit.According to this utility model, by the external seal wire of the near-end at control crank (as 0.014 " seal wire); make it to stretch in function profile section conduit part; with practical function profile section conduit part stretch or crooked, by the seal wire in control crank, control function profile section conduit part and switch mutually between ground state and deployed condition.In operation process, by control crank, pass seal wire, control function profile section conduit and be partly deployed condition, so that conduit arrives target target position.When arriving target target position, withdraw from control crank inner guide wire, make function profile section conduit partly be ground state, realize conduit nature spiral type or annular, to start radio-frequency (RF) ablation.Function profile section conduit part is divided when ground state, and diameter is greater than blood vessel diameter, makes each electrode blood vessel wall that all can recline completely.In this way, realize the supravasal electrode target position that can effectively recline, thereby reduced the time that conduit arrives target position and ensures the power that enough reclines of controlling, and can keep conduit can effectively strut in blood vessel, avoid the stimulation that blood vessel melts due to pulse radiation frequency and contingent spasm is even narrow.In addition, what adopt due to electrode is the structure being coated on from the conduit circumference of the nearly side part of blood vessel wall, crooked radian is identical with the crooked radian of function profile section conduit part under ground state, so increase the degree that electrode and blood vessel closely recline and melt, thereby realize thoroughly blocking-up adventitia sympathetic fiber.
According to embodiment of the present utility model, control crank comprises female Luer, seal wire cut-off device and buttock line socket.Female Luer, in order to connecting tee valve or other saline conductor, thinks that electrode provides saline.The passing through the buttock line socket being connected with electrode on control crank of the signal of telecommunication of electrode and energy and realizing with corresponding radio-frequency (RF) ablation equipment connection.Seal wire cut-off device, in order to seal wire is passed into the far-end of conduit, makes function profile section conduit partly reach deployed condition.
Preferably, control crank also comprises that handle pushes away and turns round.By handle, push away and turn round connecting stay wire, to control the curved variation can curved segment conduit part dividing.
This utility model is by being coated on from the design of the electrode on the conduit circumference of the nearly side part of blood vessel wall, closely more effectively recline with vascularization, thereby reach the object of blocking-up adventitia sympathetic fiber, and because ring electrode not adopts traditional closed-loop structure, but adopt the annular mode of part, so reduced within the specific limits the area of electrode blocking blood flow, thereby reduced patient vessel, kidney and the damage of other Functional tissue.
Accompanying drawing explanation
Fig. 1 is the overall structure schematic diagram of screw type conduit, wherein also shows control crank;
Fig. 2 is the overall structure schematic diagram of ring-like conduit, wherein also shows control crank;
Fig. 3 is the structural representation of spiral type function profile section conduit part;
Fig. 4 is the local enlarged diagram of electrode;
Fig. 5 is the schematic diagram of the deployed condition of spiral type function profile section conduit part in art;
Fig. 6 is the schematic diagram of the ground state of spiral type function profile section conduit part in art;
Fig. 7 is the hatching along Fig. 6 a- aart in the axial view of ground state of spiral type function profile section conduit part;
Fig. 8 is the axial view along the spiral type function profile section conduit part of the hatching b-b of Fig. 1;
Fig. 9 is the axial view along the main paragraph conduit part of the hatching c-c of Fig. 1;
Figure 10 is the schematic diagram of four lumens (only showing salt water cavity) of spiral type function profile section conduit part;
Figure 11 is the data parameters chart of four lumens (only showing salt water cavity) of spiral type function profile section conduit part.
Reference numerals list
1-spiral type function profile section conduit part; 2-main paragraph conduit part; 3-control crank;
4-can curved segment conduit part divide; 5-annular function profile section conduit part
101-handle push button; 102-female Luer; 103-seal wire cut-off device;
104-buttock line socket; 105-holding screw;
201-is coated on from the electrode on the conduit circumference of the nearly side part of blood vessel wall; 202-fixing glue; 203-electrode hole for water spraying;
204-0.014 " seal wire; 205-electrode cambered surface;
The enlarged drawing of 301-electrode; Four lumens of 302-spiral type function profile section conduit part; Three lumens of 303-annular function profile section conduit part
401-Brine Pipe;
The guidewire lumen of two remote electrodes of 501-; The guidewire lumen of two proximal electrodes of 502-; 503-0.014 " guidewire lumen; 504-salt water cavity
601-wire;
The salt water hole 1 of 701-spiral type function profile section conduit part; The salt water hole 2 of 702-spiral type function profile section conduit part; The salt water hole 3 of 703-spiral type function profile section conduit part; The salt water hole 4 of 704-spiral type function profile section conduit part
The distance in L1-salt water hole 1 and salt water hole 2; The distance in L2-salt water hole 2 and salt water hole 3; The distance in L3-salt water hole 3 and salt water hole 4; The distance of the distal-most end of L4-salt water hole 4 and conduit; The specific embodiment
Below in conjunction with accompanying drawing, this utility model specific embodiment is elaborated.
For convenience of description, used term " far-end " and " near-end " here, the one end close to operating side is near-end, away from one end of operating side, is far-end.
Figure 1 shows that and the utlity model has the overall structure schematic diagram being coated on from the screw type conduit of the electrode on the conduit circumference of the nearly side part of blood vessel wall, wherein 1 is spiral type function profile section conduit part, 2 is main paragraph conduit part, and 3 is control crank, and 4 for can curved segment conduit part dividing.
Function profile section conduit part 1 can be switched between ground state and deployed condition.Meanwhile, electrode 201 is set on the outside of this part, it is coated on the conduit circumference of the nearly side part of blood vessel wall.In this example, this part adopts four lumens 302.0.014 " seal wire 204 is by the guidewire lumen of four lumens 302, to realize the control to the form of function profile section conduit part 1.Main paragraph conduit part 2 is interior can lead to 0.014 " seal wire 204, wire 601, Brine Pipe 401(be referring to Fig. 9), can also lead to bracing wire.Function profile section conduit part 1 and main paragraph conduit part 2 can be made by materials such as polyurethane, polyimides, polyetheramides, polyamide.Control crank 3 is divided into band handle to be pushed away and turns round 101 and be not with handle to push away and turn round two kinds of specifications, and handle pushes away turns round 101 by the fixedly bracing wire of the clamp devices such as screw, in order to control stretching of bracing wire, thereby reach, controls the curved variation that can curved segment conduit part divides 4.Control crank also comprises female Luer 102, seal wire cut-off device 103, buttock line socket 104, holding screw 105, wherein female Luer 102 is in order to connecting tee valve or other saline conductor, with four lumens 302 of thinking distal end of catheter, provide saline, seal wire cut-off device 103 is 0.014 " seal wire 204 enters the access road of conduit; and buttock line socket 104 provides the signal of telecommunication and energy for catheter ablation electric discharge, and holding screw 105 is controlled the adjustment screw of can curved segment conduit part dividing 4 for control crank 3.Can curved segment conduit part divide 4 to be similarly four lumens, comprise salt water cavity, guidewire lumen, bracing wire chamber and guidewire lumen, can curved segment conduit part divide 4 at bracing wire intracavity, by glue and bracing wire, to be connected as a single entity.Can curved segment conduit part divide 4 to dock by glue is bonding with four lumens 302 and main paragraph conduit part 2 respectively.Handle by slip control crank pushes away turns round 101, pulls the bracing wire of bracing wire intracavity, thus realize can curved segment conduit 4 curved adjusting.
Figure 2 shows that the overall structure schematic diagram of ring-like conduit, wherein 5 is annular function profile section conduit part, and 2 is main paragraph conduit part, and 3 is control crank, and 4 for can curved segment conduit part dividing.On the outside of function profile section conduit part 5, electrode 201 is set, it is coated on the conduit circumference of the nearly side part of blood vessel wall.In this example, this part adopts three lumens 303.Main paragraph conduit part 2 is interior can lead to bracing wire, wire 601, Brine Pipe 401.Function profile section conduit part 5 and main paragraph conduit part 2 can be by polyurethane, polyimides, polyetheramides, and the materials such as polyamide are made.Control crank 3 is divided into band handle to be pushed away and turns round 101 and be not with handle to push away and turn round two kinds of specifications, and handle pushes away turns round 101 by the fixedly bracing wire of the clamp devices such as screw, in order to control stretching of bracing wire, thereby reach, controls the curved variation that can curved segment conduit part divides 4.Control crank 3 also comprises female Luer 102, buttock line socket 104, holding screw 105, wherein female Luer 102 is in order to connecting tee valve or other saline conductor, with three lumens 303 of thinking distal end of catheter, provide saline, buttock line socket 104 provides the signal of telecommunication and energy for catheter ablation electric discharge, and holding screw 105 is controlled the adjustment screw of can curved segment conduit part dividing 4 for control crank 3.Can curved segment conduit part divide and be similarly three lumens, be respectively salt water cavity, guidewire lumen and bracing wire chamber, can curved segment conduit part divide 4 at bracing wire intracavity, by glue and bracing wire, to be connected as a single entity.Can curved segment conduit part divide 4 to dock by glue is bonding with three lumens 303 and main paragraph conduit part 2 respectively.Handle by slip control crank 3 pushes away turns round 101, pulls the bracing wire of bracing wire intracavity, thereby realizes the curved adjusting that can curved segment conduit part divides 4.
Below with reference to screw type conduit, be described.But the feature the following describes and structure go for ring-like conduit equally.In addition, in following examples, 4 electrodes are set.But electrodeplate is not limited to 4, but can be other quantity, as 6.
Figure 3 shows that the structural representation of the function profile section conduit part of screw type conduit.In this example, 201 are coated on from the electrode on the conduit circumference of the nearly side part of blood vessel wall, and electrode surface is provided with 12 onesize electrode hole for water sprayings 203, so that saline passes through, thereby reach the effect that tissue and electrode are lowered the temperature.Electrode 201 is attached to the outside of function profile section conduit part (being four lumens 302 in this example) by be coated with the mode of fixing glue 202 at edge.In addition, 0.014 " seal wire 204 by guidewire lumen 503(referring to Fig. 8) enter four lumens 302, and change by self the ground state of Hardness Control function profile section conduit part 1.
Fig. 4 is the enlarged drawing of 301 parts in Fig. 3, shows the details of electrode of the present utility model.The crooked radian of the crooked radian of the electrode cambered surface 205 of this electrode and function profile section conduit part under ground state is identical, thereby reach, increases electrode and blood vessel and closely reclines and melt to realize thorough blocking-up adventitia sympathetic fiber.In this example, function profile conduit part 1 is provided with altogether vertically 4 electrodes and discharges for radio-frequency (RF) ablation.
Figure 5 shows that the function profile section conduit part schematic diagram in deployed condition in operation process being coated on from the screw type conduit of the electrode on the conduit circumference of the nearly side part of blood vessel wall that has of the present utility model, wherein 204 is 0.014 " seal wire, 201 is for being coated on from the electrode on the conduit circumference of the nearly side part of blood vessel wall.In operation, described conduit is by penetrating 0.014 " seal wire 204 makes the deployed condition of function profile section conduit part 1 in stretching; and at this moment the diameter of function profile section conduit part is much smaller than the diameter of blood vessel; at conduit, by ventral aorta, enter thus renal artery and find in the process that melts target spot and can not cause mechanical damage to human vas, at utmost for patient provides safety assurance.
Figure 6 shows that the function profile section conduit part schematic diagram in ground state in operation process being coated on from the screw type conduit of the electrode on the conduit circumference of the nearly side part of blood vessel wall that has of the present utility model, wherein 201 for be coated on from the electrode on the conduit circumference of the nearly side part of blood vessel wall, 203 for electrode hole for water spraying, 401 be Brine Pipe.In discharge process, the female Luer 102 perfusion saline by control crank 3, arrive electrode through Brine Pipe 401, realize to electrode and tissue cooling, for patient provides safety assurance.When function profile section conduit part 1 is in deployed condition and find and melt after target spot, recall 0.014 " seal wire 204; make function profile section conduit part 1 recover ground state; at this moment the diameter of function profile section conduit part is greater than blood vessel diameter, make each electrode all can recline completely blood vessel wall and 90 °, interval each other.And because electrode package is overlying on the conduit circumference of the nearly side part of blood vessel wall, increase electrode and blood vessel closely recline and melt to realize thorough blocking-up renal artery adventitia sympathetic fiber.
Fig. 7 is the axial view along the ground state of function profile section conduit part in the art of the hatching a-a of Fig. 6, and wherein 201 for being coated on from the electrode on the conduit circumference of the nearly side part of blood vessel wall, 203 hole for water sprayings that are electrode.As shown in Figure 8, function profile section conduit part is divided when ground state, adjacent electrode each other be spaced apart 90 °.In this way, can guarantee that conduit of the present utility model blocks adventitia sympathetic fiber effectively.
Fig. 8 is the axial view along the function profile section conduit part of the hatching b-b of Fig. 1 and Fig. 2,501 is the guidewire lumen of two remote electrodes, 502 is the guidewire lumen of two proximal electrodes, 503 is 0.014 " guidewire lumen; 504 is salt water cavity, with thinking that outside normal saline enters human vas through conduit passage is provided.This utility model be for 4 groups of conductor configurations of four electrodes 2 guidewire lumen.By this method, effectively prevent the winding risk between wire, avoided affecting product regular picture.
Fig. 9 is that wherein 401 is Brine Pipe, in discharge process along the axial view of the main paragraph conduit part of the hatching c-c of Fig. 1 and 2, by the female Luer perfusion normal saline to control crank 3, through salt water cavity, arrive electrode, realize to electrode and tissue cooling, for patient provides safety assurance; 204 is 0.014 " seal wire, seal wire is by four lumens 302 of guidewire lumen entered function profile section conduit part 1, and changes by self the ground state of Hardness Control function profile section conduit part; 601 is wire, is connected with electrode, contains TC, RF line in wire, the TC line surface temperature of reaction electrode in time wherein, and for human body provides safety assurance, RF line provides electric flux for catheter ablation electric discharge.
Figure 10 is the schematic diagram that comprises that section that shows salt water hole of four lumens of spiral type function profile section conduit part.701,702,703 and 704 be salt water hole, wherein salt water hole is respectively salt water hole 704,703,702,701 from far-end to near-end, normal saline flows into the rear inflow blood vessel of electrode hole for water spraying 203 of electrode by above-mentioned salt water hole, thereby reaches the effect of tissue and electrode cooling.L1, L2, L3 and L4 are respectively between pitch-row between salt water hole 701 and 702, salt water hole 702 and 703 distance between the pitch-row between pitch-row, saline 703 and 704, salt water hole 704 and the distal-most end of conduit.In this example, distance L 4 is 33-35mm, and electrode spacing L3, L2 and L1 are 7mm.
Figure 11 is the data parameters figure of that section that comprises salt water hole of four lumens of spiral type function profile section conduit part, wherein the first saline hole area (unit: mm that classifies saline hole 701-704 as 2), order is from near-end to far-end, rear four row are respectively the water flow (units: 10 of salt water hole 701-704 -8m 3/ s).When saline process salt of the same area water hole, can corresponding decline by near-end to the flow of far-end saline.Experimental data shows, from far-end to near-end, the linkage in two adjacent far-end salt water holes and two adjacent near-end salt water holes is eager to excel in whatever one does compared with the linkage between all the other two holes, so reduce the water-outlet area in two salt water holes of near-end, increase the water-outlet area in two salt water holes of far-end simultaneously, can guarantee that brine flow is uniformly distributed.In this example, to catheter perfusion 17ml/ minutes (approximately 28.3 * 10 -8mm 3/ s), during brine flow, the flow that can realize each salt water hole is roughly the same.As can see from Figure 11, when the area ratio of salt water hole 704:703:702:701 is 9:7:4:3, the water flow of each salt water hole 701-704 is respectively 7.1,7.2,7.2He 6.7(unit 10 -8m 3/ s), keep basically identical.
This utility model is not limited to the particular content described in the above-mentioned specific embodiment.

Claims (13)

1. a radio frequency ablation catheter, described conduit comprises function profile section conduit part and main paragraph conduit part, electrode is arranged on the outside of described function profile section conduit part, and described function profile section conduit part can be switched between ground state and deployed condition, wherein under ground state, described function profile section guiding-tube bend, so that electrode note is by blood vessel wall, under deployed condition, described function profile section conduit partly stretches to move in blood vessel, it is characterized in that, described electrode package is overlying on the conduit circumference of the nearly side part of blood vessel wall.
2. conduit according to claim 1, is characterized in that, described function profile section conduit part is divided into spiral type or annular.
3. conduit according to claim 1 and 2, is characterized in that, in described function profile section conduit part, is provided with vertically 4 or 6 electrodes.
4. conduit according to claim 1 and 2, is characterized in that, the tube wall of described function profile section conduit part is also provided with salt water hole, in order to provide salt aquaporin to each electrode.
5. conduit according to claim 4, is characterized in that, in described function profile section conduit part, is provided with vertically 4 electrodes, and the area in 4 salt water holes is the ratio of 9:7:4:3 by far-end to near-end.
6. conduit according to claim 1 and 2, is characterized in that, described function profile section conduit partly adopts multi-lumen tube, comprises guidewire lumen, salt water cavity, guidewire lumen.
7. conduit according to claim 1 and 2, is characterized in that, the crooked radian of described electrode is identical with the crooked radian of described function profile section conduit part under ground state.
8. conduit according to claim 1 and 2, is characterized in that, described conduit also comprises and can curved segment conduit part divide, and it is between described function profile section conduit part and main paragraph conduit part are divided.
9. conduit according to claim 8, is characterized in that, describedly can curved segment conduit part divide employing multi-lumen tube, comprises guidewire lumen, salt water cavity, guidewire lumen and bracing wire chamber, and in bracing wire chamber, be connected as a single entity described can curved segment conduit part dividing with bracing wire.
10. conduit according to claim 9, is characterized in that, the changeover portion between described that can curved segment conduit part divide and described function profile section conduit part is divided, and described guidewire lumen and bracing wire chamber share a chamber, and this intracavity serves as a contrast smooth coating.
The induction system of 11. 1 kinds of radio frequency ablation catheters, is characterized in that, it comprises that, according to conduit and control crank described in any one in claim 1-10, this control crank divides and is connected with the main paragraph conduit part of described conduit.
12. induction systems according to claim 11, it is characterized in that, described control crank comprises female Luer, seal wire cut-off device and buttock line socket, described female Luer is in order to connect saline conductor, think that electrode provides saline, and electrode through described buttock line socket with melt discharge equipment and be connected to realize the signal of telecommunication and energy to the transmission of electrode.
13. according to the induction system described in claim 11 or 12, it is characterized in that, described control crank also comprises that handle pushes away to be turned round, its connecting stay wire.
CN201420132897.9U 2014-03-21 2014-03-21 Radiofrequency ablation catheter and conveying system thereof Expired - Lifetime CN203885613U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105997236A (en) * 2016-05-06 2016-10-12 上海安臻医疗科技有限公司 A bronchial thermoplasty catheter
CN110353795A (en) * 2018-04-09 2019-10-22 乐普(北京)医疗器械股份有限公司 A kind of multi-pole rf ablation catheter for treating resistant hypertension

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105997236A (en) * 2016-05-06 2016-10-12 上海安臻医疗科技有限公司 A bronchial thermoplasty catheter
CN110353795A (en) * 2018-04-09 2019-10-22 乐普(北京)医疗器械股份有限公司 A kind of multi-pole rf ablation catheter for treating resistant hypertension

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