CN110353795A - A kind of multi-pole rf ablation catheter for treating resistant hypertension - Google Patents

A kind of multi-pole rf ablation catheter for treating resistant hypertension Download PDF

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Publication number
CN110353795A
CN110353795A CN201810313402.5A CN201810313402A CN110353795A CN 110353795 A CN110353795 A CN 110353795A CN 201810313402 A CN201810313402 A CN 201810313402A CN 110353795 A CN110353795 A CN 110353795A
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Prior art keywords
ablation
broken line
ablation catheter
pole
sections
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CN201810313402.5A
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Chinese (zh)
Inventor
丁毅寿
张喜博
张昱昕
蒲忠杰
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Lepu Medical Technology Beijing Co Ltd
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Lepu Medical Technology Beijing Co Ltd
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Priority to CN201810313402.5A priority Critical patent/CN110353795A/en
Publication of CN110353795A publication Critical patent/CN110353795A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345Vascular system
    • A61B2018/00404Blood vessels other than those in or around the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00589Coagulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1467Probes or electrodes therefor using more than two electrodes on a single probe

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Otolaryngology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The present invention relates to interventional therapy fields, disclose a kind of multi-pole rf ablation catheter for treating resistant hypertension, claim this conduit below.It include: control handle and ablation catheter, ablation catheter includes being responsible for and melting component, is sequentially connected by proximate;Melting component includes four sections of broken line pipes and tip, and the transition location of four sections of broken line pipes is dispersed with four electrodes, has temperature sensor and conducting wire on four electrodes;Tip welds together with four sections of broken line pipes.Form of straight lines is presented when penetrating this catheter ablation component in seal wire, and when melting the component endovascular target spot position of arrival, seal wire recession ablation component automatic rebounding is in broken line form.Four distribution of electrodes are attached on blood vessel, and for arteria renalis blood vessel, four electrodes intact can be bonded with blood vessel.The present invention is able to solve the shortcomings that current spiral duct electrode cannot recline completely, improves the effect that reclines, and increase the power that reclines by this broken line form, so that ablation is more efficient.

Description

A kind of multi-pole rf ablation catheter for treating resistant hypertension
Technical field
The present invention relates to interventional therapy field, treats the ablation of resistant hypertension multi-pole rf more particularly to a kind of and lead Pipe.
Background technique
With the improvement of material living standards, human lives are endangered, the disease of life emerges one after another.In this rhythm of life In the abnormal quick age, the number of hypertensive patient is rising year by year, and its rate of climb is very fast.In the side of making the life better It, still cannot be by systolic pressure after the measure of the reasonably combined treatment of at least three kinds of antihypertensives of formula and application including diuretics It controls with diastolic pressure in target level, referred to as refractory hypertension (or resistant hypertension).Obviously these are by intractable height The crowd that blood pressure torments cannot control well blood pressure by drug.However there is problem that will generate doing for solution Method, doctors pass through the study found that the sympathetic nerve overacfivity on the arteria renalis is an important factor for causing hypertension.So I Can be achieved the purpose that by blocking part arteria renalis sympathetic nerve control blood pressure.
Effect of the invention is to be transmitted to alternating current in arteria renalis tissue by the electrode of catheter ablation component, makes it Heat is generated, increasing temperature (being generally increased to 65 DEG C) makes the sympathetic nerve of branch on the arteria renalis lose activity at high temperature, reaches To the effect of blocking part arteria renalis sympathetic nerve.To effectively control blood pressure, make to be unable to control blood pressure by common drug Patient regain health constitution.
The electrode catheter clinically applied at present is mostly spiral-shaped, after discharging in the blood vessels, due to intravascular space shape Individual difference is larger, so the electrode that the blood vessel of some shapes will lead to spiral-shaped multi-pole rf conduit cannot be sticked on all On blood vessel, cause ablation effect bad.
The present invention proposes a kind of ablation catheter being made of four sections of broken lines in order to solve this problem, transfers in its broken line Place is dispersed with four electrodes, can guarantee that four electrodes stick on vascular wall completely in this way, and its power that reclines is bigger, from And depth of ablation and area are enhanced, so that ablation effect is more preferable, improve the cure rate of patient.
Summary of the invention
(1) technical problems to be solved
Resistant hypertension multi-pole rf ablation catheter is treated the object of the present invention is to provide a kind of, is solved spiral-shaped more The electrode of pole radiofrequency catheter cannot all stick on the problem of blood vessel, to improve ablation efficiency, and it reclines power more It increases, to enhance depth of ablation, so that ablation effect is more preferable, improves the cure rate of patient.
(2) technical solution
Resistant hypertension multi-pole rf ablation catheter is treated in order to solve the above technical problem, the present invention provides a kind of;
It is a kind of to treat resistant hypertension multi-pole rf ablation catheter characterized by comprising control handle and ablation are led Pipe;
The control handle is connect with the proximal end of the ablation catheter;
The ablation catheter includes sequentially connected supervisor and ablation component by proximate;
The supervisor is made of the woven tube and internal guidewire lumen, conducting wire of three-decker, and guidewire lumen and conducting wire are from ablation The distal end of conduit is always through handle tail end, and guidewire lumen is connect with the female Luer of handle tail end, conducting wire and handle tail end Electric connector welding;
The ablation component includes four sections of broken line pipes, tip and metal electrode, and the transition location of four sections of broken line pipes is dispersed with Four electrodes have temperature sensor and electrode cable on four electrodes;Tip welds together with four sections of broken line pipes.
Four sections of broken line pipes include elastic skeleton, plastic outer tube, sensor and electrode cable;
The inside of the ablation catheter is equipped with the guidewire lumen axially extended, and the guidewire lumen wears a seal wire.
The distal end of the ablation component has catheter tip.
Four sections of broken line pipes are connected with each other, and in turning point rounding off, are distributed four metal electrodes in transition portion;
Flexible skeleton keeps the form of its four sections of broken lines in four sections of broken line pipes, and one layer of plastics are wrapped up in outside Pipe.
Temperature sensor and electrode cable are respectively connected on four electrodes;
The temperature sensor buttock line and conducting wire pass through between elastic skeleton and plastic tube, then lead to guidewire lumen Enter supervisor, until handle tail end;
Four sections of broken line pipes in the blood vessels its contact point be four sections of broken line pipes return portion metal electrode;
The tip plastic material is prepared into the shape of soft smooth.
After the seal wire passes through guidewire lumen, can directly be in line four sections of broken line tube stays type;
(3) beneficial effect
It is provided by the invention a kind of to treat resistant hypertension multi-pole rf ablation catheter;
At present clinically on electrode catheter be it is spiral-shaped, after discharging in the blood vessels, due to intravascular space shape Body differs greatly, so the electrode that the blood vessel of some shapes will lead to spiral-shaped multi-pole rf conduit cannot all stick on blood On inside pipe wall;
The present invention proposes a kind of ablation catheter being made of four sections of broken line pipes, is dispersed with four electricity in its broken line turning point Pole can guarantee that four electrodes stick on vascular wall completely in this way, and its power that reclines is bigger, so that it is deep to enhance ablation Degree, so that ablation effect is more preferable, improves the cure rate of patient.
Detailed description of the invention
Fig. 1 is the overall schematic of the embodiment of the present invention;
Fig. 2 is the ablation block diagram of the embodiment of the present invention;
Fig. 3 is the cross-sectional end view of the supervisor of the embodiment of the present invention;
Fig. 4 is the cross-section cutaway view of the ablation component of the embodiment of the present invention;
Fig. 5 is the metal electrode position cross-sectional view of the embodiment of the present invention
The placement schematic diagram of the ablation component of Fig. 6 embodiment of the present invention in the blood vessels
1: ablation component;2: supervisor;3: handle;4: female Luer;5: electric connector;11: tip;12: outside ablation component Pipe;13 metal electrodes;14: broken line turning point;
21: supervisor's outer tube;22 metal nets;23 supervisor's inner tubes;24 electrode cables;25: guidewire lumen;26: seal wire;27: Temperature sensor;
101: ablation component outer tube;103: ablation component skeleton;6: blood vessel;61: gap.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiments of the present invention will be described in further detail.Following instance For illustrating the present invention, but it is not intended to limit the scope of the invention.
It is of the invention a kind of to treat resistant hypertension multi-pole rf ablation catheter, comprising: ablation shown in 5 Component 1, supervisor 2, handle 3, female Luer 4, electric connector 5.
Ablation component 1 and supervisor 2 weld together, and guarantee pad rounding off.Supervisor is fixedly arranged at 3 front end of handle, hand Handle tail has female Luer 4 and connector 5, is fixedly arranged at the tail end of handle.
Melting component 1 includes tip 11, melts component outer tube 12, melts component skeleton 103, guidewire lumen 25, temperature sensing Device 27 and electrode cable 24 form.
Tip 11 is welded by guidewire lumen 25 and ablation component outer tube 12, is fused together by welding, then at it A round and smooth transition is formed at tip 11.
The ablation component skeleton 103 for setting shape, ablation are placed between guidewire lumen 25 and ablation component outer tube 12 The shape of component skeleton 103 is in broken line shape.
Electrode cable 24 is placed between ablation component skeleton 103 and ablation component outer tube 12, the distal end of electrode cable 24 It is respectively welded on four metal electrodes 13, then all the way through the gap between supervisor's inner tube 23 and guidewire lumen 25, until hand Handle tail end.
An electrode cable 24 and a sensor 27 are placed on each metal electrode 13, electrode cable 24 is welded on gold Belong to the inner surface of electrode 13, sensor 27 is fixedly arranged at the inner surface of metal electrode 13 with the higher material of thermal conductivity coefficient.
Metal electrode 13 is cyclic structure, is covered on ablation component outer tube 12, and in the edge glue of metal electrode 13 Water carries out envelope filling, guarantees to smoothly transit.Electrode cable 24 passes through between ablation component skeleton 103 and ablation component outer tube 12, 13 inner surface of metal electrode is welded on after being pierced by below metal electrode 13.There is a layer insulating in 24 outer surface of electrode cable, It needs to carry out coat of paint to 24 welding portion of electrode cable to handle before welding.
There are four metal electrodes 13 altogether for this conduit, and each electrode is uniformly distributed, from the point of view of section, each metal electrode 13 It is that in this way after conduit enters blood vessel, can be uniformly distributed according to 90 degree of point distributions of circumferencial direction.And each electrode exists In axial direction not on a circumference.
As shown in figure 3, supervisor 2 is three layers of woven tube structure, including it is responsible for outer tube 21, metal net 22 and supervisor's inner tube 23, supervisor inner tube 23 and supervisor outer tube 21 by metal net 22 being coated on the inside, and by hot melt method will be responsible in Pipe 23, metal net 22, and supervisor's inner tube 23 are welded together completely, and supervisor 2 is made to have stronger intensity and radial support Power.
2 inside of supervisor by 12 conducting wires, wherein four be respectively four metal electrodes 13 electrode cable 24, other eight Root electrode wires be temperature sensor 27 conducting wire, this 12 conducting wires from ablation component 1 by supervisor one through to handle 3 tail End, is finally welded on electric connector 5
2 inside of supervisor is by a guidewire lumen 25, and guidewire lumen 25 is since tip 11, by being responsible for 2 through to handle 3 Tail end, guidewire lumen 25 is finally fixedly arranged in the female Luer 4 of 2 tail end of handle.
Operation consent penetrates seal wire 26 in guidewire lumen 25 from female Luer 4, until seal wire 26 is worn out from tip 11, this When ablation component 1 present form of straight lines, it is intravascular by instruments such as guiding catheters.It, will when melting the arrival patient part of component 1 In the recession to supervisor 2 of seal wire 26, component 1 is melted at this time, its original form is presented in the blood vessels, four metal electrodes 13 are complete It sticks on blood vessel.
Electric connector 5 is connected in equipment by connecting cable then, starts to melt, after ablation, then by seal wire 26 It is pushed to tip external forward, form of straight lines is presented again, then withdraws from from inside of human body by conduit for ablation component 1, completes operation.
As shown in fig. 6, four metal electrodes 13 all stick on 6 inner wall of blood vessel when ablation component 1 discharges in the blood vessels On, and the ablation component outer tube 12 between metal electrode 13 is not contacted with 6 inner wall of blood vessel, but have gap 61, thus Preferably guarantee that metal electrode 13 sticks on 6 inner wall of blood vessel, eliminates ablation component outer tube 101 and recline to metal electrode 13 Influence.
And it is involved in the present invention to the metal electrode 13 that can make of ablation component 1 recline power more to 6 inner wall of blood vessel By force, ablation effect is more preferable.
Due to the individual difference of organization of human body, everyone arteria renalis vascular morphology is different, so of the invention one Kind treatment resistant hypertension multi-pole rf ablation catheter is adapted to different vascular morphologies, to reduce distribution type in operation Time.
And a kind of resistant hypertension multi-pole rf ablation catheter for the treatment of of the invention may insure four metal electrodes No matter 13 in the internal blood vessel of what form guarantee that 4 metal electrodes 13 can stick on the inner wall of blood vessel 6 completely.
It is of the invention it is a kind of treat resistant hypertension multi-pole rf ablation catheter, seal wire penetrates guidewire lumen, until ablation Form of straight lines is presented in component, when melting the component endovascular patient part of arrival, seal wire is dropped back and is presented so that melting component Broken line form.Four electrode substeps are attached to blood vessel, and using broken line form, regardless of what shape blood vessel is, four electrodes are equal It intact can stick in vascular wall.
The present invention is able to solve the shortcomings that current spiral duct electrode cannot recline completely, is mentioned by this broken line form The high effect that reclines, and the power that reclines is increased, the ablation made is more efficient.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (8)

1. a kind of treat resistant hypertension multi-pole rf ablation catheter characterized by comprising control handle and ablation are led Pipe;
The control handle is connect with the proximal end of the ablation catheter;
The ablation catheter includes sequentially connected supervisor and ablation component by proximate;
The supervisor is made of the woven tube and internal guidewire lumen, conducting wire of three-decker, and guidewire lumen and conducting wire are from ablation catheter Distal end always through handle tail end is arrived, and guidewire lumen is connect with the female Luer of handle tail end, conducting wire and handle tail end Electric connector welding;
The ablation component includes four sections of broken line pipes, tip and metal electrode, and the transition location of four sections of broken line pipes is dispersed with four Electrode has temperature sensor and electrode cable on four electrodes;Tip welds together with four sections of broken line pipes.
Four sections of broken line pipes include elastic skeleton, plastic outer tube, sensor and electrode cable.
2. a kind of as described in claim 1 treat resistant hypertension multi-pole rf ablation catheter, which is characterized in that described to disappear The inside for melting conduit is equipped with the guidewire lumen axially extended, and the guidewire lumen may pass through a seal wire.
3. a kind of as described in claim 1 treat resistant hypertension multi-pole rf ablation catheter, which is characterized in that described four Section broken line pipe is connected with each other, and in turning point rounding off, is distributed four metal electrodes in turning point.
4. a kind of as claimed in claim 4 treat resistant hypertension multi-pole rf ablation catheter, which is characterized in that described four Flexible skeleton keeps the form of its four sections of broken lines in section broken line pipe, and one layer of plastic tube is wrapped up in outside.
5. a kind of as described in claim 1 treat resistant hypertension multi-pole rf ablation catheter, which is characterized in that described four Temperature sensor and electrode cable are respectively connected on a electrode.
6. a kind of as described in claim 1 treat resistant hypertension multi-pole rf ablation catheter, which is characterized in that the temperature Degree sensor tail and conducting wire pass through between elastic skeleton and plastic tube, then supervisor are passed through with guidewire lumen, until hand Handle tail end.
7. a kind of as described in claim 1 treat resistant hypertension multi-pole rf ablation catheter, which is characterized in that described four The contact point of section broken line pipe in the blood vessels be the metal electrode for being distributed in the turning point of four sections of broken line pipes.
8. a kind of as described in claim 1 treat resistant hypertension multi-pole rf ablation catheter, which is characterized in that described to lead Silk passes through form that after guidewire lumen, ablation component support directly can be in line.
CN201810313402.5A 2018-04-09 2018-04-09 A kind of multi-pole rf ablation catheter for treating resistant hypertension Pending CN110353795A (en)

Priority Applications (1)

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CN201810313402.5A CN110353795A (en) 2018-04-09 2018-04-09 A kind of multi-pole rf ablation catheter for treating resistant hypertension

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810313402.5A CN110353795A (en) 2018-04-09 2018-04-09 A kind of multi-pole rf ablation catheter for treating resistant hypertension

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012019156A1 (en) * 2010-08-05 2012-02-09 Medtronic Ardian Luxembourg S.A.R.L. Cryoablation apparatuses, systems, and methods for renal neuromodulation
CN103565512A (en) * 2012-07-26 2014-02-12 乐普(北京)医疗器械股份有限公司 Radiofrequency ablation catheter for renal arteries
CN203885613U (en) * 2014-03-21 2014-10-22 上海微创电生理医疗科技有限公司 Radiofrequency ablation catheter and conveying system thereof
CN104688331A (en) * 2013-12-09 2015-06-10 上海安通医疗科技有限公司 Catheter device used for regulating nerves
CN105012009A (en) * 2014-04-22 2015-11-04 上海微创电生理医疗科技有限公司 Renal artery radio frequency ablation electrode conduit
CN105078571A (en) * 2015-05-13 2015-11-25 上海魅丽纬叶医疗科技有限公司 Corrugated type radiofrequency ablation guide tube with wall-adherent adjusting wire and equipment thereof
CN105125281A (en) * 2015-05-13 2015-12-09 上海魅丽纬叶医疗科技有限公司 Corrugated radiofrequency ablation catheter and radiofrequency ablation device
CN205019161U (en) * 2015-08-12 2016-02-10 上海魅丽纬叶医疗科技有限公司 Ripple type radio frequency melts pipe and equipment with silk is adjusted to adherence

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012019156A1 (en) * 2010-08-05 2012-02-09 Medtronic Ardian Luxembourg S.A.R.L. Cryoablation apparatuses, systems, and methods for renal neuromodulation
CN103565512A (en) * 2012-07-26 2014-02-12 乐普(北京)医疗器械股份有限公司 Radiofrequency ablation catheter for renal arteries
CN104688331A (en) * 2013-12-09 2015-06-10 上海安通医疗科技有限公司 Catheter device used for regulating nerves
CN203885613U (en) * 2014-03-21 2014-10-22 上海微创电生理医疗科技有限公司 Radiofrequency ablation catheter and conveying system thereof
CN105012009A (en) * 2014-04-22 2015-11-04 上海微创电生理医疗科技有限公司 Renal artery radio frequency ablation electrode conduit
CN105078571A (en) * 2015-05-13 2015-11-25 上海魅丽纬叶医疗科技有限公司 Corrugated type radiofrequency ablation guide tube with wall-adherent adjusting wire and equipment thereof
CN105125281A (en) * 2015-05-13 2015-12-09 上海魅丽纬叶医疗科技有限公司 Corrugated radiofrequency ablation catheter and radiofrequency ablation device
CN205019161U (en) * 2015-08-12 2016-02-10 上海魅丽纬叶医疗科技有限公司 Ripple type radio frequency melts pipe and equipment with silk is adjusted to adherence

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Application publication date: 20191022