CN203737383U - Multifunctional magnetic separation rack - Google Patents
Multifunctional magnetic separation rack Download PDFInfo
- Publication number
- CN203737383U CN203737383U CN201320807999.1U CN201320807999U CN203737383U CN 203737383 U CN203737383 U CN 203737383U CN 201320807999 U CN201320807999 U CN 201320807999U CN 203737383 U CN203737383 U CN 203737383U
- Authority
- CN
- China
- Prior art keywords
- centrifuge tube
- plate
- magnetic
- magnetic separation
- lower plywood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000007885 magnetic separation Methods 0.000 title abstract description 12
- 230000003044 adaptive effect Effects 0.000 claims abstract description 7
- 239000011148 porous material Substances 0.000 claims description 26
- 239000011120 plywood Substances 0.000 claims description 24
- 238000002955 isolation Methods 0.000 claims description 21
- 239000006148 magnetic separator Substances 0.000 claims description 12
- 239000000463 material Substances 0.000 claims description 6
- 244000144985 peep Species 0.000 claims description 5
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 3
- 239000004926 polymethyl methacrylate Substances 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- VQAPWLAUGBBGJI-UHFFFAOYSA-N [B].[Fe].[Rb] Chemical compound [B].[Fe].[Rb] VQAPWLAUGBBGJI-UHFFFAOYSA-N 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 4
- 230000037431 insertion Effects 0.000 abstract 2
- 238000003780 insertion Methods 0.000 abstract 2
- 239000000696 magnetic material Substances 0.000 description 6
- 238000012360 testing method Methods 0.000 description 5
- BGPVFRJUHWVFKM-UHFFFAOYSA-N N1=C2C=CC=CC2=[N+]([O-])C1(CC1)CCC21N=C1C=CC=CC1=[N+]2[O-] Chemical compound N1=C2C=CC=CC2=[N+]([O-])C1(CC1)CCC21N=C1C=CC=CC1=[N+]2[O-] BGPVFRJUHWVFKM-UHFFFAOYSA-N 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 241000700605 Viruses Species 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229910052701 rubidium Inorganic materials 0.000 description 1
- IGLNJRXAVVLDKE-UHFFFAOYSA-N rubidium atom Chemical compound [Rb] IGLNJRXAVVLDKE-UHFFFAOYSA-N 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Landscapes
- Centrifugal Separators (AREA)
Abstract
The utility model discloses a multifunctional magnetic separation rack. The multifunctional magnetic separation rack comprises a centrifuge tube shelf and a magnetic base, wherein the centrifuge tube shelf and the magnetic base are two independent parts which can be assembled; the magnetic base comprises a bottom plate and a solid-core magnetic separation plate which is perpendicularly adhered to the bottom plate; a plurality of permanent magnets uniform in size and thickness are evenly distributed in the magnetic separation plate; the centrifuge tube shelf comprises an upper layer plate, a lower layer plate and two side plates; an insertion hole adaptive to the magnetic separation plate is formed in the middle of the long axis of each of the upper layer plate and the lower layer plate; centrifuge tube holes different in diameter are formed in the upper layer plate, and corresponding centrifuge tube fixing holes are formed in the lower layer plate; centrifuge tube holes adaptive to centrifuge tubes of 15ml and/or 50ml in specification are formed in each side plate; a vertical middle plate for connecting the upper layer plate with the lower layer plate is arranged at each of the two sides of the insertion hole; corresponding centrifuge tube fixing holes are formed in each vertical middle plate. By virtue of the multifunctional magnetic separation rack, samples to be treated can be demagnetized easily; the multifunctional magnetic separation rack is applicable to centrifuge tubes of different specifications, allows multiple samples to be operated simultaneously, and achieves a convenient and rapid operation effect.
Description
Technical field
The utility model belongs to Bioexperiment equipment technical field, is specifically related to a kind of multifunction magnetic separator frame for large biological molecule magnetic sample separating experiment.
Background technology
In the research field such as biology, medical science, extract and separate various large biological molecules, if the bioactive molecules such as cell, DNA, RNA, protein, virus are infrastest operations.Traditional separating and extracting process is wasted time and energy, and loses greatlyr, and extraction efficiency is low, and is difficult to carry out extensive Multi-example operation.Magnetic separation technique is to join in the solution that contains sample to be separated in conjunction with the magnetic material of sample to be separated, after magnetic material and the abundant combination of sample to be separated, by magnetic separation rack, solution is applied to external magnetic field, under the effect of outside magnetic field, the magnetic material that is combined with sample to be separated from solution enrichment out, thereby realize the separation of sample to be separated.
The magnetic part of commercially available common magnetic separation rack product is generally fixed on centrifuge tube shelf, therefore need sample cell to transfer on other nonmagnetic centrifuge tube shelfs in degaussing step, operation is inconvenience comparatively, also easily causes sample to obscure even and pollutes; Function is comparatively single, while processing the centrifuge tube of different model, need to change different magnetic frames, wastes time and energy.
Utility model content
The above-mentioned defect existing for existing magnetic separation rack, the applicant, through Improvement, provides a kind of light degaussing that realizes pending sample, is suitable for different size centrifuge tube, and multiple sample multifunction magnetic separator frame that can simultaneously operate.
The technical solution of the utility model is as follows:
Multifunction magnetic separator frame, comprises centrifuge tube shelf and magnetic bases, it is characterized in that: described centrifuge tube shelf and magnetic bases be two independently can assembled part; Described magnetic bases are made up of with the vertical solid Magnetic Isolation plate that is adhered to this base plate base plate, are evenly distributed with the permanent magnet of some block size thickness homogeneous in described Magnetic Isolation plate; Described centrifuge tube shelf comprises top plate, lower plywood and biside plate; Described top plate and lower plywood major axis central authorities offer the jack suitable with described Magnetic Isolation plate, realize described Magnetic Isolation plate and insert easily and extract; Described top plate offers the centrifugal pore of different pore size, and lower plywood offers corresponding centrifuge tube fixing hole; Described side plate offers the centrifugal pore of adaptive 15ml and/or 50ml specification centrifuge tube, is provided with the vertical intermediate plate that connects described top plate and lower plywood in described jack both sides, offers corresponding centrifuge tube fixing hole on this intermediate plate.
Its further technical scheme is:
The centrifugal pore aperture of described top plate arranges according to different size centrifuge tube carries out independent assortment, and described specification comprises 200 μ l, 0.5ml, 1.5ml, 2ml.
After assembling, the position of described permanent magnet in described Magnetic Isolation plate arranges and can ensure the magnetic material in test tube to attract to be gathered in test tube wall one side and have certain distance apart from the pipe end, to facilitate pipettor to absorb supernatant.
Described centrifugal pore axial line keeps certain distance with corresponding described centrifuge tube fixing hole axial line, makes centrifuge tube bottom press close to described Magnetic Isolation plate, to ensure enough magnetic force.
The centrifugal pore of described top plate and lower plywood centrifuge tube fixing hole are tangent with described jack edge and leave opening at tangent place respectively, to ensure the retractility of described centrifugal pore and fixing hole, strengthen the fixation to centrifuge tube.
Described lower plywood also offers the square peep hole tangent with described centrifuge tube fixing hole, long 2～12mm, and wide 1～10mm, leaves opening in tangent place, is convenient to observe during lower than described centrifuge tube shelf lower plywood at centrifuge tube liquid level Magnetic Isolation situation in it.
Described permanent magnet material is rubidium iron boron.
Described centrifuge tube shelf and magnetic bases are PMMA material, white or water white transparency.
Preferably,
Described top plate length is 30～200mm, and wide is 30～60mm, and described lower plywood length is 30～200mm, and wide is 30～60mm; Described base plate is wide is 38～75mm, described Magnetic Isolation thickness of slab 5～10mm; Described jack is wide is 6.5～12.5mm.
Described permanent magnet number is 1～16, and thickness is 3～6mm, and width is 8～15mm, and length is 15～25mm, and after assembling, described lower plywood centrifuge tube fixing hole axial line is 1～5mm to the distance of described permanent magnet.
The centrifugal pore axial line of described top plate and lower plywood centrifuge tube fixing hole axial line distance are 1～5mm, and the centrifugal pore axial line of described side plate and intermediate plate centrifuge tube fixing hole axial line distance are 5～8mm.
Described intermediate plate is 75～100mm apart from side plate distance.
Described peep hole length is 2～12mm, and wide is 1～10mm.
The technique effect that the utility model is useful is:
The utility model adopts the detachable and sectional design of centrifuge tube shelf and magnetic bases uniqueness, on the one hand can be by integrated operations such as centrifuge tube shelf vibrate separately, on the other hand, the magnetic that can realize sample after the two assembling is separated, centrifuge tube shelf is removed and can be realized light degaussing from magnetic bases, convenient to operation, and applicable different size centrifuge tube, the disposable effective separation that realizes large biological molecule magnetic material in batch sample, greatly improve operating efficiency, effectively avoid sample to obscure and cross pollution, can be widely used in the experiment such as Magnetic Isolation of large molecular activity material in the experiment of biology or medical domain.
Brief description of the drawings
Fig. 1 is the utility model detailed description of the invention structural representation, wherein, and 1: centrifuge tube shelf, 2: magnetic bases, 3: base plate, 4: Magnetic Isolation plate, 5: permanent magnet, 6: top plate, 7: lower plywood, 8: side plate, 9: jack, 10: centrifuge tube fixing hole (lower plywood), 11: intermediate plate, 12: centrifuge tube fixing hole (intermediate plate), 13: centrifugal pore (top plate), 14: centrifugal pore (side plate), 15: peep hole.
Fig. 2 is the utility model detailed description of the invention centrifuge tube shelf centrifuge tube shelf structural representation.
Detailed description of the invention
Below in conjunction with accompanying drawing, the utility model is specifically described.
As shown in Figure 1 and Figure 2, this multifunction magnetic separator frame comprises centrifuge tube shelf 1 and magnetic bases 2, the two be two independently can assembled part; Magnetic bases 2 are by the wide 60mm of entity acrylic base plate 3() with the vertical thick 9.22mm of solid Magnetic Isolation plate 4(that is adhered to this base plate) form, in Magnetic Isolation plate 4, be evenly distributed with the rubidium Fe-B permanent magnet 5(thickness 5mm of 8 block size thickness homogeneous, width 12mm, long 20mm); Centrifuge tube shelf 1 comprises the long 177mm of top plate 6(, wide 60mm), the long 177mm of lower plywood 7(, wide 60mm) and biside plate 8; Top plate 6 and lower plywood 7 major axis central authorities offer the jack 9(wide 11.3mm suitable with Magnetic Isolation plate 4), realize Magnetic Isolation plate 4 and insert easily and extract; Top plate 6 offers two rows totally 20 centrifugal pores 13, wherein 12 of the adaptive centrifugal pores of 1.5ml, and 8 of the adaptive centrifugal pores of 200 μ l, lower plywood offers 12 corresponding 1.5ml centrifuge tube fixing holes 10; Side plate 8 is offered the adaptive centrifugal pore 14 of 2 15ml, is provided with the vertical intermediate plate 11 that connects top plate 6 and lower plywood 7 in jack 9 both sides, offers 2 corresponding centrifuge tube fixing holes 12 on this intermediate plate, and intermediate plate 11 is 86.56mm with the distance of above-mentioned side plate 8; Centrifugal pore 13 axial lines and corresponding centrifuge tube fixing hole 10 axial line distances are 4.6mm, and centrifugal pore 14 axial lines are 6mm with corresponding centrifuge tube fixing hole 12 axial line distances, make centrifuge tube press close to permanent magnet 5 and ensure Magnetic Isolation; Centrifugal pore 13 and centrifuge tube fixing hole 10 are tangent with jack 9 edges and leave opening at tangent place respectively, to ensure the retractility of centrifugal pore 13 and fixing hole 10, strengthen the fixation to centrifuge tube; After assembling, centrifuge tube fixing hole 10 axial lines are 3mm to the distance of permanent magnet 5, can ensure the magnetic material in test tube to be gathered in test tube wall one side and to have certain distance apart from the pipe end, to facilitate pipettor to absorb supernatant; Lower plywood 7 also offers the square peep hole 15(long 6.7mm tangent with centrifuge tube fixing hole, wide 3.3mm), leave opening in tangent place, be convenient to observe during lower than described centrifuge tube shelf lower plywood at centrifuge tube liquid level Magnetic Isolation situation in it; Centrifuge tube shelf 1 and magnetic bases 2 are PMMA material, milky.
When use, first the test tube that pending sample is housed is placed in by specification in the centrifugal pore 13 or 14 of top plate 6 adaptations, fixed with centrifuge tube fixing hole 10 or 12, can separately centrifuge tube shelf 1 be placed in to vibration on vortex oscillation device mixes, in the time of needs Magnetic Isolation, centrifuge tube shelf 1 and magnetic bases 2 to be assembled, the magnetic that can realize sample separates, centrifuge tube shelf 1 is removed and can be realized light degaussing from magnetic bases 2, convenient to operation.
More than describing is to explanation of the present utility model, is not the restriction to utility model, and the utility model limited range, referring to claim, within protection domain of the present utility model, can be done any type of amendment.
Claims (7)
1. multifunction magnetic separator frame, comprises centrifuge tube shelf and magnetic bases, it is characterized in that: described centrifuge tube shelf and magnetic bases be two independently can assembled part; Described magnetic bases are made up of with the vertical solid Magnetic Isolation plate that is adhered to this base plate base plate, are evenly distributed with the permanent magnet of some block size thickness homogeneous in described Magnetic Isolation plate; Described centrifuge tube shelf comprises top plate, lower plywood and biside plate; Described top plate and lower plywood major axis central authorities offer the jack suitable with described Magnetic Isolation plate; Described top plate offers the centrifugal pore of different pore size, and lower plywood offers corresponding centrifuge tube fixing hole; Described side plate offers the centrifugal pore of adaptive 15ml and/or 50ml specification centrifuge tube, is provided with the vertical intermediate plate that connects described top plate and lower plywood in described jack both sides, offers corresponding centrifuge tube fixing hole on this intermediate plate.
2. multifunction magnetic separator frame as claimed in claim 1, is characterized in that: the centrifugal pore aperture of described top plate arranges according to different size centrifuge tube carries out independent assortment, and described specification comprises 200 μ l, 0.5ml, 1.5ml, 2ml.
3. multifunction magnetic separator frame as claimed in claim 1, is characterized in that: described centrifugal pore axial line keeps certain distance with corresponding described centrifuge tube fixing hole axial line, makes centrifuge tube bottom press close to described Magnetic Isolation plate.
4. multifunction magnetic separator frame as claimed in claim 1, is characterized in that: the centrifugal pore of described top plate and lower plywood centrifuge tube fixing hole are tangent with described jack edge and leave opening at tangent place respectively.
5. multifunction magnetic separator frame as claimed in claim 1, is characterized in that: described lower plywood also offers the square peep hole tangent with described centrifuge tube fixing hole, leaves opening in tangent place.
6. multifunction magnetic separator frame as claimed in claim 1, is characterized in that: described permanent magnet material is rubidium iron boron.
7. multifunction magnetic separator frame as claimed in claim 1, is characterized in that: described centrifuge tube shelf and magnetic bases are PMMA material, white or water white transparency.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320807999.1U CN203737383U (en) | 2013-12-10 | 2013-12-10 | Multifunctional magnetic separation rack |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320807999.1U CN203737383U (en) | 2013-12-10 | 2013-12-10 | Multifunctional magnetic separation rack |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203737383U true CN203737383U (en) | 2014-07-30 |
Family
ID=51337247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320807999.1U Expired - Lifetime CN203737383U (en) | 2013-12-10 | 2013-12-10 | Multifunctional magnetic separation rack |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203737383U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105665132A (en) * | 2014-11-20 | 2016-06-15 | 瀚吉康生物科技（北京）有限公司 | Combined type magnetic frame |
| CN106190827A (en) * | 2015-05-07 | 2016-12-07 | 深圳华大基因科技服务有限公司 | For separating magnetic frame and the centrifuge tube of biological sample and separating apparatus |
-
2013
- 2013-12-10 CN CN201320807999.1U patent/CN203737383U/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105665132A (en) * | 2014-11-20 | 2016-06-15 | 瀚吉康生物科技（北京）有限公司 | Combined type magnetic frame |
| CN106190827A (en) * | 2015-05-07 | 2016-12-07 | 深圳华大基因科技服务有限公司 | For separating magnetic frame and the centrifuge tube of biological sample and separating apparatus |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20140730 |