CN203646395U - Arterial perfusion device for in-vitro tissues - Google Patents
Arterial perfusion device for in-vitro tissues Download PDFInfo
- Publication number
- CN203646395U CN203646395U CN201320851839.7U CN201320851839U CN203646395U CN 203646395 U CN203646395 U CN 203646395U CN 201320851839 U CN201320851839 U CN 201320851839U CN 203646395 U CN203646395 U CN 203646395U
- Authority
- CN
- China
- Prior art keywords
- perfusion
- box body
- arterial
- utility
- model
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The utility model provides an arterial perfusion device for in-vitro tissues. The arterial perfusion device comprises a systolic pressure connecting pipe (1), a diastolic pressure connecting pipe (2), a perfusion box body (3), a flap valve (4) and a rotating shaft (5), wherein the systolic pressure connecting pipe (1) is communicated with a first outlet of the perfusion box body (3); the diastolic pressure connecting pipe (2) is communicated with a second outlet of the perfusion box body (3); the flap valve (4) is arranged in the perfusion box body (3) and rotates in the perfusion box body (3) by virtue of the rotating shaft (5). By virtue of the rotation of the flap valve in the perfusion box body, the device disclosed by the utility model can be used for simulating an arterial systolic pressure and a diastolic pressure generated by heartbeats of an animal so as to implement perfusion of the in-vitro tissues, so that the perfusion of a protective agent is relatively effective, the protective effect is relatively good after low-temperature refrigeration, the survive rate of replantation is relatively high, and no injury of blood vessels is caused.
Description
Technical field
The utility model relates to a kind of arterial perfusion device of in vitro tissue, belongs to Medical Devices technical field.
Background technology
In the migration process of the complex tissues such as in vitro limbs, tissue block, its key technology is protectantly import completely and derive.And for fresh in vitro tissue, in vitro before its arterial pressure along with heartbeat is beaten together, contraction, diastole that blood vessel replaces.But conventional device for casting generally adopts constant pressure perfusion at present, if the tissue after in vitro is given constant pressure stimulation and can be caused lasting contraction, the spasm of tiny blood vessels, make liquid cannot enter completely, equably tissue, thereby cannot reach the perfusion of deep fascia and skin, finally directly affect the authenticity of experimental result.Meanwhile, continual pressure also can cause the damage of blood vessel.
Summary of the invention
The utility model is to solve the employing constant pressure perfusion existing in the perfusion technique of existing in vitro tissue can cause lasting contraction or the spasm of tiny blood vessels and can cause the problem of injury of blood vessel, and then a kind of arterial perfusion device of in vitro tissue is provided.For this reason, the utility model provides following technical scheme:
An arterial perfusion device in vitro tissue, comprising: systolic pressure tube connector, diastolic pressure tube connector, perfusion box body, clack valve and rotating shaft; Systolic pressure tube connector is connected with the first outlet of perfusion box body, and diastolic pressure tube connector is connected with the second outlet of perfusion box body, and clack valve is arranged in perfusion box body and by rotating shaft and rotates in perfusion box body.
The utility model rotates in perfusion box body by clack valve; the SAP power, the diastole pressure that can simulated animal heartbeat produce pour in vitro tissue artery; make protectant perfusion more effective; after deep-frozen, protect better effects if; survival rate of replantation of severed is higher, and can not cause injury of blood vessel.
Accompanying drawing explanation
In order to be illustrated more clearly in the technical scheme of the utility model embodiment, below the accompanying drawing of required use during embodiment is described is briefly described, apparently, accompanying drawing in the following describes is only embodiment more of the present utility model, for those of ordinary skills, do not paying under the prerequisite of creative work, can also obtain according to these accompanying drawings other accompanying drawing.
Fig. 1 is the structural representation of the arterial perfusion device of the in vitro tissue that provides of embodiment of the present utility model;
Fig. 2 is the first use state intention of the arterial perfusion device of the in vitro tissue that provides of embodiment of the present utility model;
Fig. 3 is the second use state intention of the arterial perfusion device of the in vitro tissue that provides of embodiment of the present utility model.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the utility model embodiment is clearly and completely described, obviously, described embodiment is only the utility model part embodiment, rather than whole embodiment.Based on the embodiment in the utility model, those of ordinary skills are not making the every other embodiment obtaining under creative work prerequisite, all belong to the scope of the utility model protection.
Embodiment of the present utility model provides a kind of arterial perfusion device of in vitro tissue, as shown in Figure 1, comprising: systolic pressure tube connector 1, diastolic pressure tube connector 2, perfusion box body 3, clack valve 4 and rotating shaft 5; Systolic pressure tube connector 1 is connected with the first outlet of perfusion box body 3, and diastolic pressure tube connector 2 is connected with the second outlet of perfusion box body 3, and clack valve 4 is arranged in perfusion box body 3 and by rotating shaft 5 and rotates in perfusion box body 3.
The operation principle of the arterial perfusion device of the in vitro tissue that this embodiment provides is: after described device is connected with traditional transfusion device; be connected with arteries by sleeve pipe soft needle; in animal in vitro tissue, pour into protectant; along with the rotation of clack valve 4; the pressure of perfusion is also in continuous variation, thus can simulated animal angiosthenia fluctuation.And can measure systolic pressure and the diastolic pressure of animal by systolic pressure tube connector 1 and diastolic pressure tube connector 2.
In the optional embodiment of the utility model one, described device can also comprise perfusion input pipe 7, and perfusion input pipe 7 is connected with the 3rd outlet of perfusion box body 3.
Concrete, in the time that rotating shaft 5 drives clack valve 4 to rotate, if in position as shown in Figure 2, pouring into input pipe 7, clack valve 4 is connected with diastolic pressure tube connector 2; If in position as shown in Figure 3, pouring into input pipe 7, clack valve 4 is connected with systolic pressure tube connector 1.In the rotation process of clack valve 4, the pressure of perfusion is also in continuous variation, thereby realizes the filling process of simulated animal angiosthenia fluctuation.
In the optional embodiment of the utility model one, described device can also comprise adjustable speed motor 6, and the moment output of adjustable speed motor 6 is connected with the moment input of rotating shaft 5.
Concrete, by the adjustment of rotational speed of adjustable speed motor 6 to after consistent with the heart rate of particular animal, can make clack valve 4 along with the predefined rotational speed of adjustable speed motor 6, and filling process is changed between state as shown in Figures 2 and 3, thereby realize the filling process of simulation different animals angiosthenia fluctuation.
The technical scheme that adopts this embodiment to provide; rotate in perfusion box body by clack valve; the SAP power, the diastole pressure that can simulated animal heartbeat produce pour in vitro tissue artery; make protectant perfusion more effective; after deep-frozen, protect better effects if; survival rate of replantation of severed is higher, and can not cause injury of blood vessel.
The above; it is only preferably embodiment of the utility model; but protection domain of the present utility model is not limited to this; any be familiar with those skilled in the art the utility model embodiment disclose technical scope in; the variation that can expect easily or replacement, within all should being encompassed in protection domain of the present utility model.Therefore, protection domain of the present utility model should be as the criterion with the protection domain of claim.
Claims (3)
1. an arterial perfusion device in vitro tissue, is characterized in that, comprising: systolic pressure tube connector (1), diastolic pressure tube connector (2), perfusion box body (3), clack valve (4) and rotating shaft (5); Systolic pressure tube connector (1) is connected with the first outlet of perfusion box body (3), diastolic pressure tube connector (2) is connected with the second outlet of perfusion box body (3), and clack valve (4) is arranged in perfusion box body (3) and by rotating shaft (5) and rotates in perfusion box body (3).
2. the arterial perfusion device of in vitro tissue according to claim 1, it is characterized in that, described device also comprises adjustable speed motor (6), and the moment output of adjustable speed motor (6) is connected with the moment input of rotating shaft (5).
3. the arterial perfusion device of in vitro tissue according to claim 1, is characterized in that, described device also comprises perfusion input pipe (7), and perfusion input pipe (7) is connected with the 3rd outlet of perfusion box body (3).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320851839.7U CN203646395U (en) | 2013-12-19 | 2013-12-19 | Arterial perfusion device for in-vitro tissues |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320851839.7U CN203646395U (en) | 2013-12-19 | 2013-12-19 | Arterial perfusion device for in-vitro tissues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203646395U true CN203646395U (en) | 2014-06-18 |
Family
ID=50912847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320851839.7U Expired - Fee Related CN203646395U (en) | 2013-12-19 | 2013-12-19 | Arterial perfusion device for in-vitro tissues |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203646395U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194749A (en) * | 2015-08-10 | 2015-12-30 | 天津理工大学 | Intermittent type double pulsatile flow perfusion method for reducing foreign matter deposition on blood vessel walls |
| CN105561425A (en) * | 2015-12-16 | 2016-05-11 | 天津理工大学 | 1/3 time intermittent single pulsating flow perfusion method capable of reducing foreign matters deposited on vascular wall |
| CN106409102A (en) * | 2016-08-30 | 2017-02-15 | 天津理工大学 | Bionic perfusion method of non-smooth blood vessel model used for liver perfusion |
| CN114176069A (en) * | 2022-01-24 | 2022-03-15 | 青岛大学附属医院 | Transfer device is deposited to separation heart |
-
2013
- 2013-12-19 CN CN201320851839.7U patent/CN203646395U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194749A (en) * | 2015-08-10 | 2015-12-30 | 天津理工大学 | Intermittent type double pulsatile flow perfusion method for reducing foreign matter deposition on blood vessel walls |
| CN105194749B (en) * | 2015-08-10 | 2018-01-23 | 天津理工大学 | A kind of double pulsating flow pouring methods of the batch (-type) for reducing deposition of foreign material vascular wall |
| CN105561425A (en) * | 2015-12-16 | 2016-05-11 | 天津理工大学 | 1/3 time intermittent single pulsating flow perfusion method capable of reducing foreign matters deposited on vascular wall |
| CN106409102A (en) * | 2016-08-30 | 2017-02-15 | 天津理工大学 | Bionic perfusion method of non-smooth blood vessel model used for liver perfusion |
| CN114176069A (en) * | 2022-01-24 | 2022-03-15 | 青岛大学附属医院 | Transfer device is deposited to separation heart |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN203646395U (en) | Arterial perfusion device for in-vitro tissues | |
| CN212342143U (en) | Heart bionic device | |
| CN203276696U (en) | Simulation apparatus for arteriopuncture and venipuncture and endovascular treatment | |
| CN110148344A (en) | A kind of intravenous injection simulation teching device | |
| CN106023759B (en) | A kind of intravenous injection simulator for medical care teaching | |
| CN110176174A (en) | A kind of intravenous injection practicing arm models | |
| CN204049978U (en) | Internal arteriovenous fistula operation nursing pad | |
| CN207722222U (en) | Cerebral artery occlusion recycles exchange device again | |
| CN205068972U (en) | Sound arteries and veins analogue means of puncture teaching | |
| CN205041508U (en) | Continuous type renal puncture needle of adjustable length | |
| CN203710428U (en) | Disposable fast e multi-purpose body cavity effusion drainage device | |
| CN203982666U (en) | Internal arteriovenous fistula model | |
| CN208988851U (en) | A kind of arteries and veins pillow pulse-taking instrument | |
| CN208243586U (en) | A kind of liver-and-gall surgery drag hook | |
| CN208551954U (en) | The multidirectional more plane auxiliary stands of ultrasonic puncture | |
| CN205028502U (en) | Radial artery puncture simulates exercise device | |
| CN105147415B (en) | Milk cow vein Special remaining needle | |
| CN206183792U (en) | High efficiency aponeurosis dilator | |
| CN204766951U (en) | Artery sheath pipe | |
| CN203873821U (en) | Venous transfusion hemostasis clamp for emergency medicine | |
| CN108451574A (en) | A kind of infusion intravenous pressing device | |
| CN204468387U (en) | A kind of coronary intervention arm fixing device | |
| CN203710077U (en) | Power plant used for thrombus remover | |
| CN201783072U (en) | Cold crystalloid cardioplegia perfusion syringe needle for infants | |
| CN204542577U (en) | Abdomen wears rear antiseep bellyband |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140618 Termination date: 20141219 |
|
| EXPY | Termination of patent right or utility model |