CN212342143U

CN212342143U - heart bionic device

Info

Publication number: CN212342143U
Application number: CN202020647563.0U
Authority: CN
Inventors: 万峰
Original assignee: Shanghai East Hospital
Current assignee: Shanghai East Hospital
Priority date: 2019-12-28
Filing date: 2020-04-24
Publication date: 2021-01-12
Anticipated expiration: 2030-04-24
Also published as: CN212342142U; CN113053221A; CN113053222A; CN110853471A

Abstract

The present application relates to a heart bionic device, which is used to connect a heart model, the heart model has an atrium and a ventricle, and the device includes: a liquid storage unit; unit and the atrium; a fluid outlet, the two ends of which are respectively used to connect the fluid storage unit and the ventricle; and a fluid drive unit that is used to connect the heart model; wherein, the fluid storage unit, the inlet The liquid part, the liquid outlet part, the liquid driving unit and the heart model constitute a liquid circulation circuit. The pulsatile fluid circulation system of the present application can simulate blood circulation, the heart can contract and eject blood, diastolic filling, valve opening and closing, and coronary circulation, so a high degree of bionic heart model can be realized.

Description

Heart bionic device

Technical Field

The application relates to the technical field of medical bionic equipment, in particular to a heart bionic device.

Background

The heart disease is the first killer of human health, coronary heart disease, aortic stenosis or insufficiency, mitral valve prolapse and the like are common heart diseases of middle-aged and elderly people, the risks of heart failure death and sudden death are high, and a large number of children patients with congenital heart disease are also very effective means for surgical treatment of the diseases. The cardiac surgery treatment is performed by directly taking a patient as an operation object, has strong professionalism, and only a small number of doctors can participate in actual operation, but besides the doctors, a large number of other people need to participate in the operation to study, research, train and the like, such as medical universities, research institutions, medical equipment enterprises, hospitals and the like, so the cardiac bionic device is born at the right moment.

However, the heart is pulsating in the cardiac surgery process, the heart in the simulation model is generally static, and even if some bionic devices simulate the heartbeat, the simulation effect is poor because the bionic devices are mainly realized by extruding the heart model, so that the using effect of the bionic devices is poor.

Chinese patent CN205665950U discloses a robot simulated heart which realizes blood pumping and blood returning by the action between permanent magnet and electromagnet to simulate the heart function of human or animal. Chinese patent CN210091524U discloses a pulse teaching device, which utilizes the movable connection between a rolling device and a simulated pulse wave slot to make a connecting cylinder slide left and right to perform piston movement, so as to drive a piston rod to extrude the bionic heart, thereby simulating the beating of the heart, but the above simulated heart has no liquid circulation system, so the heart will not contract to eject blood, dilate and fill, open and close valves, and circulate coronary artery, therefore, the highly bionic heart model can not be realized.

SUMMERY OF THE UTILITY MODEL

In view of the above, the present application is directed to overcoming the shortcomings of the prior art and providing a cardiac biomimetic apparatus. The apparatus for connecting to a heart model having an atrium and a ventricle, the apparatus comprising:

a liquid storage unit;

the two ends of the liquid inlet part are respectively used for connecting the liquid storage unit and the atrium;

the two ends of the liquid outlet part are respectively used for connecting the liquid storage unit and the ventricle; and

a fluid drive unit for connecting the heart model;

the liquid storage unit, the liquid inlet part, the liquid outlet part, the liquid driving unit and the heart model form a liquid circulation loop.

Optionally, the heart model is a biomimetic heart model or an animal heart.

Optionally, the liquid outlet part is connected with a pressure regulating valve and a pressure gauge.

Optionally, the liquid inlet portion is connected to the left atrium of the heart model, the liquid outlet portion is connected to the left ventricle of the heart model, and the liquid driving unit is connected to the left ventricle of the heart model.

Optionally, the liquid inlet portion is connected to the right atrium of the heart model, the liquid outlet portion is connected to the right ventricle of the heart model, and the liquid driving unit is connected to the right ventricle of the heart model.

Optionally, liquid inlet portion has two, liquid outlet portion has two, and first liquid inlet portion connects the left atrium of heart model, and first liquid outlet portion connects the left ventricle of heart model, and second liquid inlet portion connects the right atrium of heart model, and second liquid outlet portion connects the right ventricle of heart model.

Optionally, the liquid driving unit includes a pump and an electric air compressor, the electric air compressor is connected to the pump, the pump is connected to the heart model through a pump pipe, and the pump is an air-powered diaphragm pump, a plunger pump or a piston pump.

Optionally, the liquid driving unit is a "pump and machine integrated" device, and is an electric diaphragm pump, a plunger pump, and a piston pump for generating pulsating flow, and the liquid driving unit is connected to the heart model through a pump tube.

Optionally, the inlet and outlet of the pump are connected in parallel to the first opening of the ventricle through pump tubes, respectively.

Optionally, the ventricle has a second opening and a third opening, and the inlet and the outlet of the pump are connected to the second opening and the third opening respectively through a pump tube.

Optionally, the pump tube comprises a threaded insert, a first washer and a nut; one end of the threaded insertion pipe is provided with a T-shaped table, the other end of the threaded insertion pipe is provided with threads, the end provided with the T-shaped table is inserted into a ventricle of the heart model, and the first gasket and the nut are screwed up with the threaded insertion pipe from the outside of the ventricle wall.

Optionally, the pump tube further includes a second gasket, the second gasket is in a contracted state when the threaded insertion tube is inserted into the ventricle of the heart model, and the second gasket is in an expanded state and clings to the inner wall of the ventricle when the first gasket and the nut are screwed with the threaded insertion tube from the outside of the ventricle wall.

Another aspect of the present application provides a cardiac biomimetic apparatus, comprising:

a biomimetic model of a heart having an atrium and a ventricle,

a liquid storage unit;

a liquid driving unit for connecting the heart bionic model;

the liquid storage unit, the liquid inlet part, the liquid outlet part, the liquid driving unit and the heart bionic model form a liquid circulation loop.

The application provides a bionic device of heart is connected with outside heart model by stock solution unit, liquid inlet portion, liquid outlet portion and liquid drive unit and forms fluid circulation system, relies on the fluid drive unit to provide the interior power of beating for the heart model, in order to promote liquid circulation, and let the bionic beat of heart of separation, can simulate blood circulation, can realize that cardiac contraction jets blood, the diastole is full, the valve switching, coronary circulation, consequently, can realize the high bionical of heart model. In addition, the heart bionic device is low in cost and convenient to operate.

Drawings

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.

FIG. 1 is a schematic structural diagram of a cardiac biomimetic apparatus provided in the present application;

fig. 2 is a schematic external view of a cardiac bionic device provided by the present application.

In the figure: the heart model comprises a heart model 1, a pump, a liquid driving unit 2, a liquid storage unit 3, a liquid inlet portion 4, a liquid outlet portion 5, a pressure regulating valve 6, a pump pipe 7, a pressure gauge 8, an electric air compressor 9, a pulmonary vein 15 and an aorta 16.

Detailed Description

In order to make the objects, technical solutions and advantages of the present application more apparent, the technical solutions of the present application will be described in detail below. It is to be understood that the embodiments described are only a few embodiments of the present application and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without making any creative effort, shall fall within the protection scope of the present application.

An embodiment of the present application provides a cardiac biomimetic apparatus for interfacing a heart model, the heart model having an atrium and a ventricle, the apparatus comprising: the liquid storage unit is used for storing liquid; a liquid inlet part for connecting the liquid storage unit and the atrium, respectively; a liquid outlet part which is respectively used for connecting the liquid storage unit and the ventricle; and a liquid driving unit for driving the liquid to flow; the liquid storage unit, the liquid inlet part, the liquid outlet part, the liquid driving unit and the heart model form a liquid circulation loop.

The term "coupled" includes, but is not limited to, connected, fixedly coupled, movably coupled, directly coupled, indirectly coupled, and the like.

The liquid is blood, water, red ink or other liquid. The heart model includes, but is not limited to, a heart bionic model, and hearts of animals such as pigs, cows, sheep, etc., the heart model has an aorta including a left atrium and a right atrium, and a pulmonary vein, and the ventricles include a left ventricle and a right ventricle. In addition, the heart model is also provided with valve leaflets, the hearts of different animals can be slightly different, the bionic heart model can simulate the human heart, and four valves are arranged in the heart, namely an aortic valve for connecting a left ventricle and an aorta, a pulmonary valve for connecting a right ventricle and a pulmonary artery, a mitral valve for connecting a left atrium and the left ventricle, and a tricuspid valve for connecting the right atrium and the right ventricle.

The liquid inlet part can be communicated with the atrium through the pulmonary veins of the heart model, and the liquid outlet part can be communicated with the ventricle through the aorta of the heart model. The liquid storage unit includes, but is not limited to, a liquid storage bottle and the like. The liquid storage unit 3 can be a bottle for filling the heart and the pipeline with liquid, the bottle has the capacity of at least 1L, and the bottle is provided with two openings, one is a liquid outlet and the other is a liquid inlet.

The liquid circulation system formed by the heart bionic device and the heart model can simulate blood circulation, and the heart can contract to eject blood, dilate and fill, open and close the valve and circulate coronary artery, so that the high bionic performance of the heart model can be realized.

In another embodiment of the present application, the cardiac biomimetic apparatus further comprises a cardiac biomimetic model, i.e. the entire fluid circulation system is sold as a kit.

The technical solutions provided by the embodiments of the present application are described in detail below with reference to the accompanying drawings.

Fig. 1 is a schematic structural diagram of a cardiac bionic device provided by the present application. As shown in fig. 1, the heart bionic device comprises a liquid storage unit 3, a liquid inlet part 4, a liquid outlet part 5 and a liquid driving unit. In this embodiment, the liquid driving unit includes a pump 2 and an electric air compressor 9, the pump 2 is connected to the heart model 1 through a pump pipe 7, and the liquid outlet portion 5 is provided with a pressure regulating valve 6 and a pressure gauge 8, although the pressure regulating valve 6 and the pressure gauge 8 may be provided at other positions, such as the liquid inlet portion 4. The fluid inlet portion 4 is a channel connecting the atrium and the reservoir unit 3, and the fluid outlet portion 5 is a channel connecting the ventricle and the reservoir unit 3.

The pressure regulating valve 6 may be a low flow resistance valve that can be used to regulate the arterial outflow pressure.

The pressure gauge 8 may be a sphygmomanometer for measuring a simulated arterial pressure.

In the present embodiment, the pump 2 and the electric air compressor 9 are operated independently, the pump 2 includes, but is not limited to, a single-chamber diaphragm pump, a plunger pump, and a piston pump, and the speed and frequency of the pump are adjustable. The electric air compressor 9 provides power for the pump 2, and the power source is compressed air and can generate pulsating flow.

The pump 2 and the electric air compressor 9 may also be a "pump-and-machine integrated" device, such as an integrated diaphragm pump, plunger pump, piston pump, etc., and may be a reciprocating single-chamber pump capable of generating pulsating flow, and if the diaphragm pump, plunger pump, piston pump are dual-chamber or multi-chamber, they need to be processed to become a pulsating flow pump, and may be used.

In an embodiment of the present application, the liquid inlet 4 is connected to the left atrium of the heart model 1, the liquid outlet 5 is connected to the left ventricle of the heart model 1, and the liquid driving unit is connected to the left ventricle of the heart model 1.

Wherein the left ventricle may be provided with only one opening (first opening) to which the inlet and outlet of the pump 2 may be connected in parallel, and inserted into the left ventricle through the opening. In addition, the left ventricle may be provided with two openings (a second opening and a third opening) through which the inlet and outlet of the pump 2 are inserted into the left ventricle, respectively.

In another embodiment of the present application, the liquid inlet 4 is connected to the right atrium of the heart model 1, the liquid outlet 5 is connected to the right ventricle of the heart model 1, and the liquid driving unit is connected to the right ventricle of the heart model 1. The design of the opening may be similar to the example of the left ventricle described above.

In another embodiment of the present application, there are two liquid inlets and two liquid outlets, the first liquid inlet is connected to the left atrium of the heart model, the first liquid outlet is connected to the left ventricle of the heart model, the second liquid inlet is connected to the right atrium of the heart model, and the second liquid outlet is connected to the right ventricle of the heart model. This connection highly simulates the blood flow conduit of the human heart.

The pump pipe 7 is a bridge channel for connecting the pump 2 and the ventricle, and the pump pipe 7 comprises a threaded insertion pipe, a first gasket, a screw cap and a liquid inlet and outlet parallel pipe of the pump. One end of the threaded insertion pipe is provided with a T-shaped table, the other end of the threaded insertion pipe is provided with threads, and after the end provided with the T-shaped table is inserted into the left ventricle, the threaded insertion pipe is screwed up with the threaded insertion pipe from the outside of the ventricle wall by using a first gasket and a screw cap; the pump pipe 7 can also be connected with an extension pipe at the tail end of the threaded insertion pipe and can be used for being connected to the port of a liquid inlet and outlet parallel pipe of the pump; the inlet and outlet parallel pipes of the pump are connected to the inlet and outlet of the pump 2.

The pump tube further comprises a second gasket, the second gasket can be a soft gasket, when the threaded insertion tube is inserted into the ventricle of the heart model, the second gasket is in a contraction state, when the first gasket and the nut are naturally opened from the outside of the ventricle wall and can be inosculated with the inner wall of the ventricle in the process of screwing the threaded insertion tube, the second gasket is matched with the first gasket, the sealing effect on the ventricle is good, and blood leakage can be effectively prevented.

In one embodiment of the present application, the inlet and outlet of the pump are each connected in parallel to the first opening of the ventricle through a pump tube.

In another embodiment of the application, the ventricle has a second opening and a third opening, to which the inlet and the outlet of the pump are connected by a pump tube, respectively.

The principle of realizing the bionic beating of the heart by the bionic beating device of the heart is as follows:

the heart model 1 is used as a carrier, anticoagulated animal blood or red ink is used as circulating liquid, and the pump 2 provides pulsating power to push blood circulation. The method specifically comprises the following steps: a hole is formed in the left ventricle wall of the heart model 1, one end of a pump pipe 7 is inserted into the hole, then the pump pipe is screwed and pressed from the outside of the ventricle wall through a first gasket and a screw cap, the other end of the pump pipe 7 is connected with a pump 2, one ends of a liquid inlet part 4 and a liquid outlet part 5 are respectively connected with inner holes of a pulmonary vein 15 and an aorta 16 and are tied tightly, and the other ends of the liquid inlet part 4 and the liquid outlet part 5 are communicated with a liquid storage unit 3, so that a closed-loop circulating system is formed. When the liquid storage unit 3 is filled with liquid and is filled into a circulating system, the electric air compressor 9 is started to drive the pump 2 to work, the pump 2 rapidly sucks liquid from the left ventricle, the aortic valve is automatically closed at the moment, the mitral valve is automatically opened, the liquid flows out of the liquid storage unit 3 and enters the left ventricle through the liquid inlet part 4, the pulmonary vein 15 and the left atrium, and the left ventricle is sucked and contracted at the moment; after the pump 2 finishes the pumping action, liquid is rapidly injected into the left ventricle, the mitral valve is closed automatically, the left ventricle is rapidly dilated and filled, the aortic valve is opened by pressure difference at the later diastole stage, the blood injection action of the heart model 1 is realized, the liquid is injected into the aorta 16, passes through the liquid outlet part 5 and flows back to the liquid storage unit 3, and the primary liquid circulation is finished. The bionic beating of one cardiac cycle of the heart model 1 is realized by one absorption and one ejection of the pump 2, and the beating frequency and amplitude of the heart model 1 can be adjusted through the working frequency and the pressure of the pump 2; the afterloaded arterial pressure of the heart model 1 can be observed from a pressure gauge 8, and the pressure regulating valve 6 can regulate the magnitude of the afterloaded arterial pressure.

The bionic beating of the heart model 1 can realize the dynamics of ventricular ejection, diastole, valve opening and closing, coronary circulation, arterial pressure rise and the like, and can be simulated to be completely the same as the physiology.

In another embodiment, the circulatory system may also be connected to the artery and vein of the right atrium by the liquid storage unit 3, and the pump tube 7 is inserted into the right ventricle to form a right heart circuit, thereby performing the pulsation of the right heart.

In another embodiment, the circulatory system may also be configured such that the artery and vein of the left and right heart are connected in parallel by the reservoir unit 3, and the pump tube 7 is inserted into the left and right ventricles simultaneously, thereby forming a bi-cardiac circuit to perform bi-cardiac pulsation.

In another embodiment, the bi-cardiac circuit can be connected to only one of the left and right heart chambers by the pump tube 7 under the condition that the ventricular diaphragm muscle is opened, so that the bi-chamber realizes the connected bi-cardiac pulsation.

The heart bionic device provided by the application, bionical degree is high, the effect can compare favourably with the animal experiment, various simulation operations are carried out under this scene, if the heart does not stop jumping and bridges, the heart beats, coronary blood circulation, coronary filling and beating, the scene of incision blood spray, doctor's moving knife and sutural handle etc. are all the same as animal in vivo experiment or human body operation environment, aortic valve and mitral valve are all rhythmic opening and closing, the heart can contract and shoot blood, the diastole is sufficient, these can all be observed through the endoscope, under radiography or supersound, the difficult heart simulation operations such as valve replacement of wicresoft, preceding venereal disease defect restoration, mitral valve chordae repair etc. can be carried out.

Compared with the prior art, the heart bionic device is low in cost, simple to operate and free from the limitation of time and place; the method for the bionic beating of the isolated heart has high simulation degree.

The popularization and application of the application have the following social significance and value: the method can cultivate cardiac surgeons in batches, quickly improve the operation skills, enable more doctors to go to clinic early, perform minimally invasive and non-stop jumping operations, reduce risks and save more lives of patients with heart diseases.

It is understood that the same or similar parts in the above embodiments may be mutually referred to, and the same or similar parts in other embodiments may be referred to for the content which is not described in detail in some embodiments.

It should be noted that, in the description of the present application, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. Further, in the description of the present application, the meaning of "a plurality" means at least two unless otherwise specified.

In the description herein, reference to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the application. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

Although embodiments of the present application have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present application, and that variations, modifications, substitutions and alterations may be made to the above embodiments by those of ordinary skill in the art within the scope of the present application.

Claims

1. a heart bionic device, this device is used for connecting a heart model, described heart model has atrium and ventricle, it is characterized in that, this device comprises:

Liquid storage unit for storing liquid;

a liquid inlet, which is respectively used to connect the liquid storage unit and the atrium;

a fluid outlet for connecting the fluid storage unit and the ventricle, respectively; and

a fluid drive unit for driving fluid flow;

Wherein, the liquid storage unit, the liquid inlet part, the liquid outlet part, the liquid driving unit and the heart model constitute a liquid circulation circuit.

2 . The heart bionic device according to claim 1 , wherein the heart model is a heart bionic model or an animal heart. 3 .

The heart bionic device according to claim 1, wherein the liquid inlet part is connected to the left atrium of the heart model, the liquid outlet part is connected to the left ventricle of the heart model, and the liquid driving unit Connect the left ventricle of the heart model.

The heart bionic device according to claim 1, wherein the liquid inlet part is connected to the right atrium of the heart model, the liquid outlet part is connected to the right ventricle of the heart model, and the liquid driving unit Connect the right ventricle of the heart model.

5 . The heart bionic device according to claim 1 , wherein there are two liquid inlet parts and two liquid outlet parts, the first liquid inlet part is connected to the left atrium of the heart model, and the second liquid inlet part is connected to the left atrium of the heart model. 6 . A liquid outlet part is connected to the left ventricle of the heart model, a second liquid inlet part is connected to the right atrium of the heart model, and the second liquid outlet part is connected to the right ventricle of the heart model.

6 . The heart bionic device according to claim 1 , wherein the liquid driving unit comprises a pump and an electric air compressor, the electric air compressor is connected to the pump, and the pump is connected to the pump through a pump tube. 7 . The heart model is connected, and the pump is one of an aerodynamic diaphragm pump, a plunger pump, and a piston pump.

7 . The heart bionic device according to claim 1 , wherein the liquid driving unit is a “pump-machine-integrated” device, which is selected from an electric diaphragm pump, a plunger pump, and a piston pump that generate pulsatile flow. 8 . In one of them, the pump is connected to the heart model through a pump tube.

8 . The heart bionic device according to claim 7 , wherein the inlet and the outlet of the pump are respectively connected in parallel to the first opening of the ventricle through a pump tube. 9 .

9 . The heart bionic device according to claim 7 , wherein the ventricle has a second opening and a third opening, and the inlet and the outlet of the pump are respectively connected with the second opening and the third opening through a pump tube. 10 . .

10 . The bionic heart device according to claim 7 , wherein the pump tube comprises a threaded cannula, a first gasket and a nut; one end of the threaded cannula is provided with a T stage, and the other end is provided with a T stage. 11 . A thread, the end provided with the T platform is inserted into the ventricle of the heart model, and the first gasket and the nut are screwed to the threaded cannula from the outside of the ventricle wall.

11 . The heart bionic device according to claim 10 , wherein the pump tube further comprises a second gasket, when the threaded cannula is inserted into the ventricle of the heart model, the second gasket In a contracted state, when the first gasket and the nut are tightened with the threaded cannula from the outside of the ventricular wall, the second gasket is in an expanded state and abuts against the ventricular inner wall.

12. A heart bionic device, characterized in that the device comprises:

a heart bionic model having an atrium and a ventricle;

Liquid storage unit for storing liquid;

a liquid drive unit for driving the flow of liquid;

Wherein, the liquid storage unit, the liquid inlet part, the liquid outlet part, the liquid driving unit and the heart bionic model constitute a liquid circulation circuit.

13 . The heart bionic device according to claim 1 or 12 , wherein a pressure regulating valve and a pressure gauge are connected to the liquid outlet. 14 .