KR101759377B1 - Radial pulsation simulator with blood circulatory method of left atrium and left ventricle and method for simulating radial pulsation based on pressure feedback - Google Patents

Abstract

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a simulated pulse wave simulator and a method for reproducing an artificial pulse wave using closed circulating blood supply and circulation. More particularly, the present invention relates to an apparatus for reproducing an artificial pulsation wave, comprising: a left ventricular remodeling section for generating a pulsating flow; A left ventricle simulating unit supplying a fluid to the left ventricle simulating unit and having a circulating circulation function; And a pulse wave delivery unit for delivering the pulse wave delivered by the left ventricular remodeling unit to a pressure waveform. [0002] The present invention relates to an artificial pulse wave simulator employing a closed circulating blood supply and circulation system.

Description

TECHNICAL FIELD [0001] The present invention relates to a pressure-feedback-control-based artificial pulse wave simulator and a method for reproducing an artificial pulse wave using a left-ventricle and a left ventricular blood supply and circulation system. }

The present invention relates to a pressure-feedback-control-based artificial pulse wave simulator and a method for reproducing an artificial pulse wave, which employs a blood supply and circulation system of the left atrium and the left ventricle, and is capable of reproducing various pulse wave patterns expressing various diseases of cardiovascular Lt; / RTI >

Pulses can be categorized into 28 Macs by Oriental medicine. FIG. 1A shows a table showing the kinds of 28 kinds of veins. As shown in FIG. 1A, the pulse wave measured while the blood circulates through the human body is present in the bloodstream of the blood vessels of the blood vessels, blood vessels, arteries, veins, veins, veins, veins, veins, , Can be distinguished from a vena cava, a vein, a vein, a vein, a vein, a vein, a vein, a vein, a vein, a vein, a vein, a vein and a vein.

Fig. 1B is a perspective view of the conventional pulse wave simulator 1, Fig. 1C is a partial perspective view of the conventional pulse wave simulator 1, Fig. 1D is a perspective view of the conventional pulse wave simulator 1, 1E shows a partial perspective view of the supply hose portion for providing the hydraulic pressure to the model arm 2 of the conventional pulse wave simulator 1. As shown in Fig. This device uses a piston, a cylinder, and a motor that linearly moves the piston to create a pulse wave through an open-loop control of the circulating fluid. However, there is a problem that the circulation of the fluid is performed in a different manner from the human body because there is no device for acting as a left atrium, and a pressure pattern expressing various cardiovascular diseases can not be generated by controlling the open circuit.

Conventionally, there are hydraulic apparatuses which attempt to reproduce the shape similar to the blood flow of an actual heart. FIG. 2A is a perspective view of a conventional hydraulic blood-pressure drive device 3, FIG. 2B is a sectional view of part A of FIG. 2A, and FIG. 2C is a perspective view of the interior of part B of FIG. 2A.

The conventional hydraulic blood-flow drive device 3 shown in FIGS. 2A and 2B has been developed as a cardiac pump using a rotary motor and a slider-crank structure. However, when the noise and the residual vibration are severe, This device has difficulties in expressing various cardiovascular diseases because it is difficult to control precision displacement because it is coupled with a ball check valve. There is a problem that turbulence is generated by using a ball check valve.

3 (a) is a perspective view of a conventional arterial training wrist instrument 4, and FIG. 3 (b) is a perspective view of an artificial skin of a conventional arterial training wrist instrument 4 and a wrist model incorporating an arterial tube, 3c is a plan view showing the inside of the hydraulic driving device of the conventional arterial training wrist mechanism 4, and Fig. 3d is a perspective view of a portion C in Fig. 3c.

As shown in FIGS. 3A to 3D, the conventional arterial training wrist instrument 4 has been developed for training nurses using a DC geared motor and a slider crank structure to inserting syringes to find arterial blood vessels. However, There is a problem of noise and residual vibration, and it is difficult to control the precision displacement because the force and speed are coupled to each other, and also there is a problem that various cardiovascular diseases can not be expressed.

4A is a perspective view of a driving part (left side) and a main controller (right side) of the conventional hydraulic type blood flow drive system 5. FIG. 4B is a perspective view of the driving part of the conventional hydraulic type blood flow driving system 5, FIG.

The hydraulic blood flow drive system 5 shown in FIGS. 4A and 4B is a step motor, a timing belt, and a lead screw. The system is developed for precise discharge and control of fluids, and is capable of precision displacement and force control. Although the heat transfer effect is minimized, it has a disadvantage in that it is not suitable for simulating the blood flow of the heart due to the slow discharge speed of the fluid.

      Non-Invasive Blood Pressure (BP), which can store and reproduce pressure waveforms generated in the body by pneumatic pressure, can be used to evaluate the uncertainty of the pressure indicator (blood pressure sensor) Monitor Analyzer was developed by FLUKE. FIG. 5A is a perspective view showing an internal configuration of a conventional pneumatic blood pressure drive system developed by FLUKE, and FIG. 5B is a block diagram showing a configuration of a conventional pneumatic blood pressure drive system manufactured by FLUKE.

6A is a perspective view of a pneumatic blood pressure drive system manufactured by the Institute of Standards and Science, Institute of Standards and Science, and FIG. 6B is a block diagram showing the configuration of a pneumatic blood pressure drive system manufactured by the Institute of Standards and Science . 7A, 7B, and 7C are perspective views of a pneumatic blood pressure drive system manufactured by the National Institute of Standards and Technology of Medical Convergence Measurement Standards Center. The pneumatic blood pressure drive system as described above is used to make a comparison value that can calibrate the pressure gauge by simulating the pressure vibration generated in the human arm by generating the pressure vibration of the air by reciprocating the piston.

However, such a pneumatic blood pressure drive system has been developed to simulate pressure oscillations occurring in arterial blood vessels. Since the air is compressible, there is a problem that it is not suitable to be applied to the pulse wave reproducing apparatus for promoting the cuff because it is not suitable for expressing the feeling of reflected waves and blood flow generated by the incompressible blood.

Korean Patent No. 0912115 Korean Patent No. 1428532 Korea Patent Publication No. 2009-0121458 Korea Patent Publication No. 2005-0117825 Korean Patent No. 585848 Korea Patent Publication No. 2014-0109187 Korea Patent Publication No. 2009-0121459

Conventional devices including the above-mentioned patent documents have attempted to realize the function of the left ventricle using a piston, a cylinder, and a motor that linearly moves the piston, thereby making a pulsatile or pulsatile wave. However, the function of the left ventricle is important as well as the function of the left ventricle in the pulse wave of the person. The left atrium is generated by alternating positive pressure and negative pressure, so that arterial blood is sent to the left ventricle and arterial blood is supplied from the pulmonary vein again, so that closed circulation is performed in the human body. In the conventional patent documents, the functions of the left atrium are excluded, and it is difficult to make various blood flow similar to the human body.

In addition, the pressure in the left ventricle which directly makes the flow of the pulse is an important factor. In the conventional patent document, by adopting the open-loop control method without using the feedback of the pressure value, various cardiovascular diseases The pressure pattern of the pulsating wave or the pulse wave which can express the pressure wave pattern of the pulse wave can not be made.

SUMMARY OF THE INVENTION Accordingly, the present invention has been made to solve the above-mentioned problems occurring in the prior art, and it is therefore an object of the present invention to provide a cardiac pacemaker having a left atrial mass, a left atrial, A heart-shaped artery, and a radial artery mimetic part, thereby realizing a heart-shaped wave, which can reproduce a pulse wave. And to provide a method of simulator and artificial pulse wave reproducing method.

In addition, according to an embodiment of the present invention, the pressure measuring unit measures the pressure in the left ventricle in real time to feedback-control the left atrium linear driver and the left ventricle linear driver so that the left ventricular end closures, Artificial pulse wave simulator employing a closed circulating blood supply and circulation system that can be driven by simulating the circulation process of aortic valve opening, aortic valve opening, aortic valve closes, left ventricular static relaxation, left atrioventricular valve opening, rapid filling, The present invention provides a method for reproducing an artificial pulse wave.

According to an embodiment of the present invention, since the left atrioventricular valve plate existing between the left atrium and the left ventricle of the actual heart, and the insertion check valve and the discharge check valve that function as an aorta present in the discharge end of the left ventricle, The present invention provides a pressure-feedback-control-based artificial-pulse-wave simulator and a method for reproducing an artificial-pulse-wave using a blood circulation system of a left ventricle and a left ventricle in accordance with a closed circulation system that can be discharged and circulated similarly to blood have.

According to another aspect of the present invention, there is provided a method of controlling a left atrium linear driving unit, the method comprising the steps of: preparing an aortic transfusion unit and a radial artery transfusion unit, The present invention provides a simulated pulse wave simulator and a method for reproducing an artificial pulse wave using a blood supply and circulation method.

According to an embodiment of the present invention, the damping coefficient of the damper portion supporting the left ventricular cylinder and the radial artery simulating portion is made smaller than the damping coefficient of the damper portion supporting the left atrial simulator and the left ventricular linear driving portion, The present invention is to provide an artificial artery pulse wave simulator and a method for reproducing artificial artery wave that employ a circulatory blood supply and circulation system having a dustproof structure that prevents the residue from being transmitted to the radial artery simulation unit.

It is to be understood that both the foregoing general description and the following detailed description of the present invention are exemplary and explanatory and are not intended to limit the invention to the precise form disclosed. It can be understood.

SUMMARY OF THE INVENTION A first object of the present invention is to provide an apparatus for reproducing an artificial pulsation wave, comprising: a left ventricle simulating unit for generating a pulsating flow; A left ventricular syringe configured to supply a circulating fluid to the left ventricle simulator and to perform a close circulation function; And a pulse wave delivery unit for delivering the pulse wave delivered by the left ventricular remodeling unit to a pressure waveform.

The circulatory fluid delivered to the left ventricular contraction unit by the left atrial contraction unit is discharged from the left ventricular contraction unit, and a part of the circulatory fluid is delivered through the left atrial contraction unit through the aorta simulation unit. And the remainder is introduced into the radial artery simulation unit to transmit a pressure waveform and is introduced into the left atrial simulation unit and circulated.

The left ventricular simulator further includes a left ventricular cylinder having an inflow end into which the circulating fluid discharged from the left atrial firing simulator flows into and a discharge end from which the circulating fluid is discharged by the movement of the piston; A left ventricular linear driving unit for driving the piston; And an insertion check valve provided at one side of the inflow end and functioning as a left ventricular assist device, and a discharge check valve provided at one end of the inflow end to function as an aortic valve.

The discharge check valve may be a gauze valve capable of controlling the opening pressure, and the opening pressure of the discharge check valve may be greater than the opening pressure of the insertion check valve.

The left atrial modeling unit includes a circulating fluid reservoir having a discharge port through which the circulating fluid is discharged to the left ventricle simulating unit and an inlet through which the circulating fluid discharged from the pulse wave delivering unit flows, the circulating fluid being stored; A left atrium cylinder for supplying a pneumatic pressure capable of regulating a positive pressure and a negative pressure in the circulating fluid bath by a piston movement; And an atrium linear driving unit for driving the piston in the left atrium cylinder.

A connection pipe connecting the outlet of the left atrial simulation unit and the inlet end of the left ventricle simulating unit; a discharge pipe connecting between the discharge end of the left ventricle simulating unit and the pulse wave delivering unit; And a circulation tube for connecting the descending aorta simulation tube and the radial artery simulation part and the inlet of the left atrial simulation part, wherein the radial artery simulation part is provided between the discharge end and the circulation tube, And a soft soft tube for transmitting a pressure wave by the soft tube.

The apparatus may further include a tube adjusting unit for adjusting at least one of the height and the tension of the softening tube.

A second object of the present invention is to provide a method for reproducing an artificial pulsation wave, comprising: discharging a circulating fluid stored in a circulating fluid reservoir of a left atrial firing section to a connection tube by pneumatic pressure; Introducing the circulating fluid into the left ventricular cylinder of the left ventricular contraction part unidirectionally to the first specific pressure by the insertion check valve; Moving the piston by the left ventricular linear drive to pressurize the circulating fluid in the left ventricular cylinder; Wherein the pressure in the left ventricular cylinder exceeds a second specified pressure and forms a pulsating flow and the circulating fluid is discharged through the discharge check valve to the discharge tube; The pulse flow delivered by the left ventricular mass analyzer is delivered to the radial artery simulation pressure waveform; And a circulating fluid discharged from the radial artery simulation unit flows into the circulating fluid reservoir through a circulation pipe and circulates through the circulation fluid reservoir.

The first specific pressure may be greater than or equal to 1 mmHg and less than 50 mmHg, and the second specific pressure may be less than or equal to 50 and less than or equal to 100 mmHg.

The radial artery simulation unit includes a soft tube for transferring a pressure wave by a circulating fluid discharged from the left ventricle simulating unit and disposed between the discharge tube and the circulation tube, And adjusting at least one of a height, a tension, and a tension.

A third object of the present invention is to provide an artificial pulse wave reproducing system comprising: an artificial pulse wave reproducing apparatus according to the first object; A pressure measuring unit for measuring in real time the pressure in the left ventricular cylinder, which is a constituent of the left ventricle simulating unit of the artificial artery pulse wave reproducing apparatus; And a control unit for controlling driving of the left ventricular linear driving unit and the left atrium linear driving unit of the artificial pulse wave reproducing apparatus based on the pressure value measured by the pressure measuring unit. have.

In addition, the left atrial simulation unit and the left ventricle simulating unit may have a dust-proof structure to prevent the residue from being transmitted to the pulse wave transmitting unit.

The radial artery simulator hydraulic pressure measuring unit measures the pressure of the circulating fluid flowing into the radial artery simulation unit in real time. A display unit for displaying a pressure waveform based on the measurement value measured by the radial artery simulation hydraulic pressure measuring unit; And a regulating valve provided at one side of the circulation pipe to adjust the size of the pressure waveform; And at least one of the following:

A fourth object of the present invention is to provide a method for reproducing the artificial pulse wave in consideration of the positive pressure and the negative pressure of the circulatory fluid tank of the left atrial simulator using the above-mentioned artificial pulse repetition system of the third object, The control unit drives the left atrium linear driving unit and the left ventricular linear driving unit to rearrange the pistons in the left atrium cylinder and the left ventricle cylinder to close the exhaust valve; The circulating fluid stored in the circulating fluid reservoir of the left atrial simulator is discharged to the connection tube by a positive pressure of the positive pressure and the circulating fluid is discharged to the left ventricle cylinder of the left ventricle simulator by the insertion check valve, A second step of flowing into a specific pressure; A third step of opening the exhaust valve and arranging the piston in the left atrium cylinder forward to prepare a negative pressure effect; A fourth step of moving the piston in the left ventricular cylinder forward by the left ventricular linear driving unit to pressurize the circulating fluid in the left ventricular cylinder; A fifth step in which the pressure in the left ventricle cylinder exceeds a second specified pressure and forms a pulsating flow, and the circulating fluid is discharged to the discharging end; A sixth step in which the piston in the left atrium cylinder is moved backward to generate a negative pressure effect so that the circulating fluid flows into the circulating fluid reservoir through the aortic simulator and the radial artery simulator; And a seventh step of repeating the first to sixth steps. The method for reproducing the artificial artery wave according to the positive pressure and the negative pressure effect may be achieved.

In the second and sixth steps, the control unit feedback-controls driving of the left atrium linear driving unit based on the pressure value measured by the left ventricular pressure measuring unit. In the fourth and fifth steps, The control unit controls the driving of the left ventricular linear driving unit based on the pressure value measured in the left ventricular linear driving unit.

The control unit may control the movement speed of the piston of the left ventricular linear driving unit based on the measured pressure value to generate a specific pressure waveform.

Adjusting the opening pressure of the discharge check valve; Measuring the pressure of the circulating fluid flowing into the radial artery simulation section in real time; The display unit displaying the pressure waveform based on the measured value measured by the radial artery simulator hydraulic pressure measuring unit; And controlling the size of the pressure waveform by controlling the control valve provided at one side of the circulation pipe; And at least one of the following:

According to one embodiment of the present invention, since the left atrial, left ventricular, aortic, and radial artery simulation units simulating the function of the left atrium, left ventricle, aorta, and radial arteries of the actual heart are provided, It is possible to reproduce a pulse wave by applying the principle as it is.

In addition, according to an embodiment of the present invention, the pressure measuring unit measures the pressure in the left ventricle in real time to feedback-control the left atrium linear driver and the left ventricle linear driver so that the left ventricular end closures, It can be operated by simulating the circulation process of the contraction, the aortic valve opens, the release, the release valve closes, the left ventricular static relaxation, the insertion valve opens, the rapid filling, and the cardiac arrestor.

According to an embodiment of the present invention, since the left atrioventricular valve plate existing between the left atrium and the left ventricle of the actual heart, and the insertion check valve and the discharge check valve that function as an aorta present in the discharge end of the left ventricle, So that it can be circulated.

According to an embodiment of the present invention, there is provided an effect capable of preparing, generating, and generating the actual sound pressure effect by controlling the left atrium linear driving unit while controlling the pressure in the left ventricle with feedback control of the aorta simulation unit and the radial artery simulating unit .

According to an embodiment of the present invention, the damping coefficient of the damper portion supporting the left ventricular cylinder and the radial artery simulating portion is made smaller than the damping coefficient of the damper portion supporting the left atrial simulator and the left ventricular linear driving portion, The radial artery of the radial artery and the radial artery of the radial artery.

It should be understood, however, that the effects obtained by the present invention are not limited to the above-mentioned effects, and other effects not mentioned may be clearly understood by those skilled in the art to which the present invention belongs It will be possible.

BRIEF DESCRIPTION OF THE DRAWINGS The accompanying drawings, which are incorporated in and constitute a part of the specification, illustrate preferred embodiments of the invention and, together with the description, serve to further the understanding of the technical idea of the invention, It should not be construed as limited.
1A is a table showing the kinds of 28 kinds of veins,
1B is a perspective view of a conventional pulse wave simulator,
1C is a partial perspective view of a conventional pulse wave simulator,
1D is a perspective view of a model arm which is a constitution of a conventional pulse wave simulator,
FIG. 1e is a partial perspective view of a supply hose portion for providing pneumatic pressure to a model arm of a conventional pulse wave simulator,
FIG. 2A is a perspective view of a conventional hydraulic type blood-
FIG. 2B is a sectional view of a portion A in FIG. 2A,
FIG. 2C is a perspective view showing the inside of part B of FIG. 2A,
3A is a perspective view of a conventional arterial training wrist instrument,
FIG. 3B is a perspective view of a wrist model having an artificial skin and an arterial tube of a conventional arterial training wrist instrument,
FIG. 3c is a plan view showing the inside of a hydraulic driving device of a conventional arterial training wrist mechanism,
FIG. 3D is a perspective view of part C of FIG. 3C,
4A is a perspective view of a driving unit and a main controller of a conventional hydraulic blood flow drive system,
FIG. 4B is an enlarged perspective view of the driving unit and the step motor side of the conventional hydraulic blood flow drive system,
5A is a perspective view showing the internal structure of a conventional pneumatic blood pressure drive system manufactured by FLUKE,
FIG. 5B is a block diagram showing a configuration of a conventional pneumatic blood pressure drive system manufactured by FLUKE,
6A is a perspective view of a pneumatic blood pressure drive system manufactured by the Institute of Standards and Science,
FIG. 6B is a block diagram showing a configuration of a pneumatic blood pressure drive system manufactured by the National Institute of Standards and Science
FIGS. 7A, 7B, and 7C are perspective views of a pneumatic blood pressure drive system manufactured by the National Institute of Standards and Technology of Medical Convergence Measurement Standards Center,
8 is a configuration diagram of an artificial pulse wave reproducing system according to an embodiment of the present invention;
9A is a plan view of an artificial pulse wave reproducing system according to an embodiment of the present invention,
9B is a side view of the left atrial simulator according to an embodiment of the present invention,
FIG. 9c is a side view of a left ventricle simulating part according to an embodiment of the present invention,
FIG. 9D is a side view of the radial artery simulation unit according to an embodiment of the present invention, FIG.
10A is a graph showing the pressure at the root of the aorta relative to the heart action, the pressure in the left ventricle, the pressure in the left atrium,
FIG. 10B is a schematic view showing each part of the human heart,
FIG. 10C is a table summarizing the time duration of left atrial contraction, left ventricular diastolic contraction, release, static relaxation, rapid inflow, and cardiac arrest,
11 shows the pressure and volume graph in the left ventricle (left graph) and the pressure in the left ventricle (left graph) as the heart stall, the closing of the ward, the left ventricular outflow, the aortic open, the aortic valve close, the static relaxation, And volume graph,
Fig. 12 is a schematic diagram showing the heart, an ascending aorta, subclavian artery, descending thoracic aorta, and pulmonary artery of a human body,
13A is a perspective view of a closed aortic plate,
13B is a perspective view of the opposed aorta,
14A is a perspective view of a closed left ventricular septal plate,
14B is a perspective view of an open left ventricular end diaphragm,
15 is a side cross-sectional view of a left atrial simulator having a dust-proof structure according to an embodiment of the present invention,
16 is a side cross-sectional view of a left ventricle simulating part having a dustproof structure and a pulse wave transmitting part according to an embodiment of the present invention,
17 is a flowchart of a method for reproducing an artificial pulse according to an embodiment of the present invention,
18 is a block diagram illustrating a signal flow of a control unit according to an embodiment of the present invention;
FIG. 19 is a flowchart illustrating a method for reproducing an artificial pulse wave in consideration of a sound pressure effect according to an embodiment of the present invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings. However, the detailed description of known functions and configurations incorporated herein will be omitted when it may unnecessarily obscure the subject matter of the present invention.

The same reference numerals are used for portions having similar functions and functions throughout the drawings. Throughout the specification, when a part is connected to another part, it includes not only a case where it is directly connected but also a case where the other part is indirectly connected with another part in between. In addition, the inclusion of an element does not exclude other elements, but may include other elements, unless specifically stated otherwise.

< Artificial pulse wave  Reproduction system>

Hereinafter, the configuration and functions of the artificial pulse wave reproducing system 100 according to an embodiment of the present invention will be described. FIG. 8 is a block diagram illustrating a system 100 for reproducing an artificial pulse wave according to an embodiment of the present invention. 9A is a plan view of the artificial-pulse-wave reconstruction system 100 according to an embodiment of the present invention, and FIG. 9B is a side view of the left atrial simulation unit 10 according to an embodiment of the present invention. And FIG. 9C is a side view of the left ventricle simulating part 40 according to an embodiment of the present invention. 9D is a side view of the radial artery simulating unit 70 according to an embodiment of the present invention.

8, the artificial pulse wave reproducing system 100 according to an embodiment of the present invention includes a left atrial contraction unit 10, a left ventricular contraction unit 40, and a pulse wave propagating unit as shown in FIG. . 8, the pulse wave delivery unit according to an embodiment of the present invention includes the aorta simulation unit 60 and the radial artery simulation unit 70.

The artificial pulse wave reproducing system 100 according to the embodiment of the present invention is constructed by simulating the operation and operation principle of the actual heart unlike the conventional blood flow driving apparatus. That is, the left ventricle simulating unit 40 simulates the left ventricle of the actual heart to generate a pulsating flow. The left atrial examining unit 10 supplies fluid to the left ventricular simulating unit 40, and the radial artery simulating unit 70 Transmits the pulse wave delivered by the left ventricular mass analyzer 40 to the pressure waveform.

Accordingly, the fluid delivered to the left ventricle simulating unit 40 by the left atrial examining unit 10 is discharged from the left ventricular simulating unit 40 and flows into the aortic simulating unit 60 and the radial artery simulating unit 70, (10) and circulated.

8 and 9B, the left atrial contraction unit 10 according to the embodiment of the present invention includes an left atrium linear driving unit 20, a left atrium cylinder 11 and a circulating fluid tank 14 ), And the like.

8, the circulating fluid bath 14 according to an embodiment of the present invention includes a discharge port 15 in which a circulating fluid is stored and a circulating fluid is discharged to the left ventricle simulating part 40 side, And has an inlet 16 into which the circulating fluid discharged from the simulating unit 70 flows and also has an inlet pipe 19 through which the circulating fluid flowing through the aortic simulating unit 60 flows and is connected to the left atrium linear driving unit 20 The pneumatic pressure is supplied according to the set cycle.

The left atrium cylinder 11 is supplied with the air pressure to the circulating fluid bath 14 by the movement of the left atrium piston 12 provided therein. In addition, the left atrium linear driving portion 20 drives the piston 12 in the left atrium cylinder 11. The first function of the left atrium linear drive unit 20 is to discharge the circulating fluid stored in the circulating fluid reservoir 14 to the left ventricle simulating unit 40 side and the second function generates a negative pressure effect, And the circulation fluid passing through the portion 60 and the radial artery simulation unit 70 is introduced into the circulating fluid reservoir 14 again.

8 and 9B, the left atrium linear driving unit 20 includes a step motor 21, a ball screw 23, and a false socket coupler 22, oldham connecting the step motor 21 and the ball screw 23 coupler &lt; / RTI &gt; The piston 12 in the left atrium cylinder 11 reciprocates while the ball screw 23 reciprocates and the left atrium piston 12 reciprocates while the step motor 21 is driven. 14 to the circulating fluid.

Therefore, the circulating fluid in the circulating fluid bath 14 is discharged through the discharge port 15 by the pneumatic pressure supplied in a specific cycle.

It can be seen that the left ventricular contraction unit 40 according to an embodiment of the present invention can include the left ventricular cylinder 41 and the left ventricular linear driving unit 50 as shown in Figs. 8 and 9C . The circulatory fluid discharged from the circulating fluid reservoir 14 is introduced into the left ventricular cylinder 41. The left ventricular cylinder 41 is connected to the inflow end 45 And a discharge end 46 through which the circulating fluid is discharged by the movement of the left ventricular piston 44. A connection pipe 30 is connected between the discharge port 15 of the circulating fluid reservoir 14 and the inlet end 45 of the left ventricle cylinder 41.

In addition, the piston 44 in the left ventricular cylinder 41 is driven by the left ventricular linear driving unit 50, and the left ventricular linear driving unit 50 according to the embodiment of the present invention, as shown in FIGS. 8 and 9C, A left ventricular step motor 51, an encoder 52, an oldham coupler 53, a ball screw 54, and the like.

That is, the ball screw 53 connected to the Sepah coupler 53 is reciprocated by the driving of the left ventricular step motor 51, so that the piston 44 in the left ventricle cylinder 41 moves and circulates in the left ventricle cylinder 41 Thereby compressing the fluid.

The left ventricular linear driving unit 50 according to the embodiment of the present invention is only one specific embodiment and only a configuration capable of driving the piston 44 in the left ventricle cylinder 41 at a predetermined cycle and speed will be described below The scope of the present invention should not be construed as limiting the scope of the present invention.

The left ventricular cylinder 41 according to an embodiment of the present invention simulates the left ventricle of an actual heart. The left ventricular cylinder 41 according to an embodiment of the present invention substantially simulates a left ventricular valve (anteric valve) 42 and an aortic valve And a check valve (43).

As will be described later, the actual left atrioventricular valve of the heart only causes the circulating fluid to flow from the left atrium to the left ventricle side, and the open pressure corresponds to about 5 mmHg, and the aortic valve only allows the circulating fluid to be discharged from the left ventricle And an open pressure of about 80 mmHg.

8 and 9A, an insertion check valve 42 is provided on one side of the inflow end 45 of the left ventricle cylinder 41 according to an embodiment of the present invention, It can be seen that the discharge check valve 43 is provided on one side. The opening pressure of the discharge check valve 43 is greater than the opening pressure of the insertion check valve 42, and the discharge check valve 43 according to the embodiment of the present invention is configured as a gait control valve capable of controlling the opening pressure do. Therefore, as will be described later, the opening pressure of the discharge check valve 43 by the control unit 110 can be adjusted by human or by disease.

Therefore, when the circulating fluid discharged from the circulating fluid reservoir 14 exceeds the opening pressure of the insertion check valve 42, the circulating fluid is introduced into the left ventricular cylinder 41, and the left ventricular linear drive unit 50 drives the left ventricular cylinder 41, The circulating fluid is discharged to the aorta simulation portion 60 side of the pulse wave delivery portion through the discharge end 46 while forming a pulsating flow.

8 and 9A, the connecting tube 30 is connected to the discharge port 15 of the circulating fluid bath 14 and the outlet port 15 of the circulating fluid reservoir 14, And the inlet end 45 of the heat exchanger 41. The discharge end 46 of the left ventricle cylinder 41 is connected to the discharge pipe 61 of the aorta simulating part 60 and the discharge pipe 61 is connected to the descending aorta simulating pipe 62 and the radial artery simulating floating inlet 63 Quot; 8, the circulating fluid introduced from the left ventricular cylinder 41 flows into the discharge tube 61 of the aortic simulator 60, and the circulating fluid introduced into the discharge tube 61 flows into the descending aorta simulation tube The circulating fluid introduced into the descending aortic coagulation tube 62 flows into the circulating fluid reservoir 14 and flows into the radial artery simulation floating inlet 63 The circulating fluid passes through the radial artery simulating unit 70 and transmits the pressure waveform to the user.

The actual body is supplied with the negative pressure by the hydraulic pressure to flow through the aorta. The artificial pulse wave reproducing system 100 according to an embodiment of the present invention controls the left atrium linear driving unit 20 to provide the expansion pressure to the circulating fluid bath 14 in order to impart such a sound pressure effect, And provides the hydraulic pressure that can flow into the circulating fluid bath 14 through the simulating unit 60 and the radial artery simulating unit 70. This operation principle will be described later in detail.

The radial artery simulation unit 70 according to an embodiment of the present invention receives the pulse flow generated by the left ventricle simulating unit 40 and delivers the pressure waveform to the user. Specifically, the radial artery simulation unit 70 according to one embodiment of the present invention includes a soft tube 71 and a support unit 73, a tube adjustment unit 72, a magnitude control valve 74, a wrist pad 75, and the like.

The soft tube 71 according to an embodiment of the present invention functions as a blood vessel and provides a pulse wave to a user who contacts the soft tube 71 with a finger. 8 and 9A, the soft tube 71 is provided between the radial artery simulation floating inlet 63 and the circulation pipe 80 and is provided with a pressure wave form by the circulating fluid discharged from the left ventricle simulating unit 40. [ As shown in FIG.

In addition, the support part supports the end of the radial artery simulation floating inlet 63 and the end of the circulation tube 80. The height of the soft tube 71 can be adjusted by moving the soft tube 71 up and down by the tube adjusting part 72 according to the embodiment of the present invention. The soft tube 71 can be tensioned to adjust the tension, , Diseases, and the like. In addition, a magnitude control valve 74 may be provided at one side of the circulation pipe 80 of the radial artery simulation unit 70 according to an embodiment of the present invention to adjust the magnitude of the pressure waveform.

The pneumatic pulse wave generation system 100 provides the pneumatic pressure (compressive force) to the circulatory fluid bath 14 by the left atrial linear driving unit 20 and the circulatory fluid tub 14 Is discharged to the connection pipe 30 by pneumatic pressure.

When the hydraulic pressure in the connection pipe 30 exceeds the opening pressure of the insertion check valve 42, the circulating fluid is introduced into the left ventricular cylinder 41 of the left ventricle simulating part 40. The piston 44 is moved by the left ventricular linear drive unit 50 to pressurize the circulating fluid in the left ventricle cylinder 41. When the pressure in the left ventricle cylinder 41 exceeds the opening pressure of the release check valve 43 The circulating fluid is discharged to the discharge tube 61 of the aorta simulating part 60 while forming a pulsating flow.

As described above, the opening pressure of the discharge check valve 43 is greater than the opening pressure of the insertion check valve 42, and the opening pressure of the insertion check valve 42 is 1 mmHg to 10 mmHg (preferably, about 5 mmHg ), And the opening pressure of the discharge check valve 43 can be adjusted by the control unit 110, and ranges from about 50 mmHg to about 100 mmHg (preferably about 80 mmHg).

The circulating fluid discharged through the discharge check valve 43 is supplied to the circulation fluid reservoir 14 (14) as the piston 12 in the left atrium cylinder 11 of the left atrial simulation unit 10 is driven backward, And the radial artery simulating floating inlet 63 and the radial artery simulator 62 to circulate the circulating fluid to the circulating fluid bath 14 via the descending aortic coagulation pipe 62, And the circulation fluid is circulated through the circulation pipe 80 to the circulating fluid bath 14 to generate a negative pressure effect of the human body.

Also, as the circulating fluid flows into the radial artery simulation unit 70, the vein flow delivered by the left ventricle simulating unit 40 is transmitted to the pressure waveform at the radial artery simulating unit 70.

The circulating fluid discharged from the radial artery simulation unit 70 flows into the circulating fluid water tank 14 through the circulation pipe 80 and is circulated.

In addition, the artificial artery pulse wave generation system 100 according to an embodiment of the present invention includes a pressure measurement unit, and is configured to include a circulation loop (not shown), which is discharged from a left ventricular cylinder 41, The pressure of the fluid is measured in real time. That is, the pressure of the circulating fluid discharged from the left ventricle cylinder 41 to the discharging end is measured.

Specifically, the pressure measuring unit according to an embodiment of the present invention may include a left ventricular pressure measuring unit 90 and a radial artery simulation hydraulic pressure measuring unit 91, as shown in FIG. Therefore, the left ventricle pressure measuring unit 90 measures the pressure in the left ventricle cylinder 41 in real time, and the radial artery simulating unit hydraulic pressure measuring unit 91 measures the hydraulic pressure flowing into the radial artery simulating unit 70 in real time .

As described later, the control unit 110 controls the left ventricular linear driving unit 50 of the artificial-pulse-wave reproducing system 100 based on the pressure value measured by the left ventricular-pressure measuring unit 90, The control unit 110 controls the regulating valve 74 provided at one side of the circulation pipe 80 so as to regulate the pressure and the discharge pressure of the discharge valve 41, Thereby adjusting the magnitude of the waveform.

In addition, the pressure waveform applied to the radial artery simulation unit 70 based on the pressure measured by the radial artery simulation hydraulic pressure measuring unit 91 can be monitored by the display unit. Based on the pressure waveform, the controller 110 The control unit 110 can control the pressure in the left ventricle cylinder 41 and the discharge pressure by controlling the left ventricular linear drive unit 50 and the opening pressure of the discharge check valve 43, ) To control the magnitude of the pressure waveform to generate a desired pressure waveform.

Hereinafter, it will be described that the artificial pulse wave reproducing system 100 according to an embodiment of the present invention is designed in a manner similar to an actual heart. 10A is a graph showing the pressure at the root of the aorta relative to the heart action, the pressure in the left ventricle, the pressure in the left atrium, and the volume of the left ventricle. FIG. 10B is a schematic view showing each part of the human heart. FIG.

FIG. 10C is a table summarizing the time duration of left atrial contraction, left ventricular diastolic contraction, release, static relaxation, rapid inflow, and cardiac arrest. 11 shows the pressure and volume graph in the left ventricle (left graph) and the left ventricular end-diastolic volume (left graph) as the cardiac arrest, the closing of the wardrobe, the left ventricular diastolic contraction, the opening and release of the aortic valve, the aortic valve close, the static relaxation, And a graph of the pressure and the volume in the chamber.

FIG. 12 is a schematic view showing the human heart, an ascending aorta, subclavian artery, descending thoracic aortic aneurysm, pulmonary artery, FIG. 13a is a perspective view of a closed aorta, and FIG. 13b is a perspective view of an open aorta. 14A is a perspective view of an open left ventricular end diaphragm plate, and FIG. 14B is a perspective view of a closed left ventricular diaphragm plate.

As shown in Figs. 10A, 10B, 10C, and 11, the left atrium valve closes, the left ventricular static contraction, the release valve (aortic valve) opens, the release valve, the release valve closes, It can be seen that the insertion valve opens, the rapid filling, and the cardiac arrestor are circulated by one cycle.

The artificial pulse wave reproducing system 100 according to the embodiment of the present invention reproduces the same process as that of the actual heart, thereby reproducing the artificial pulse wave that is the same as that of a real human pulse wave.

Hereinafter, the structure of the dust-proof structure of the artificial-pulse-wave representing system 100 according to one embodiment of the present invention will be described. 15 is a side sectional view of a left atrial simulation unit 10 having a dust-proof structure according to an embodiment of the present invention. 16 is a side sectional view of a left ventricle simulating part 40 having a dustproof structure and a pulse wave transmitting part according to an embodiment of the present invention.

The artificial pulse wave reproducing system 100 according to an embodiment of the present invention has a dustproof structure so that residues are not transmitted to the radial artery simulating unit 70 by the left atrial examining unit 10 and the left ventricular simulating unit 40 do.

15, the step motor 21, the left atrium cylinder 11, and the circulating fluid bath 14 of the left atrium linear driving unit 20 according to the embodiment of the present invention are connected to the left atrial simulator base 25, and the left atrial simulator base 25 is installed on the support surface by the left atrium high damper 26. [ The left atrium high damper 26 is constituted by a damping coefficient that is greater than the damping coefficient of the damper unit that supports the left ventricle cylinder 41 and the damper unit that supports the radial artery simulation unit 70 as described later.

16, the step motor 51 and the ball screw 54 of the left ventricular linear driving part 50 according to the embodiment of the present invention are fixed to the left ventricular linear driving part base 47, The base 47 is supported by the high damper 48 on the supporting surface while the left ventricle cylinder 41 and the radial artery simulating part 70 are supported by the low damper 49 having a lower damping coefficient than the high damper 48. [ As shown in Fig.

The left ventricular cylinder 41 and the radial artery simulating unit 70 are arranged so as to have a damping coefficient larger than the damping coefficient of the damper unit that supports the step motor 51 and the ball screw 54 of the left atrial calibrating unit 10 and the left ventricular linear driving unit 50 The left atrial simulation unit 10 and the left ventricle simulating unit 40 have a structure in which the residuals are not transmitted to the radial artery simulating unit 70 because the damping coefficient of the supporting damper unit is made smaller.

Hereinafter, a method for reproducing an artificial pulse wave according to an embodiment of the present invention will be described. 17 is a flowchart of a method for reproducing an artificial pulse wave according to an embodiment of the present invention. 18 is a block diagram illustrating a signal flow of the controller 110 according to an embodiment of the present invention.

The method of reproducing the artificial pulse wave according to an embodiment of the present invention corresponds to the method of operating the artificial pulse wave reproducing system 100 described above.

First, the circulating fluid stored in the circulating fluid reservoir 14 of the left atrial calibrator 10 is discharged to the connection tube 30 by pneumatic pressure (S1). That is, by driving the step motor 21 of the linear driving unit 20, the piston 12 in the left atrium cylinder 11 is moved from the left side to the right side with reference to Fig. 8 by the ball screw 23, The circulating fluid is discharged from the circulating fluid reservoir 14 to the connection pipe 30 while the air is supplied to the circulating fluid reservoir 14 (S2).

Then, the circulating fluid is introduced into the left ventricular cylinder 41 of the left ventricle simulating part 40 up to the first specified pressure by the insertion check valve 42 (S3).

Next, the piston 44 is moved by the left ventricular linear drive part 50 to pressurize the circulating fluid in the left ventricle cylinder 41. [ That is, the piston 44 in the left ventricle cylinder 41 is moved from the left to the right on the basis of the one shown in Fig. 8 by the driving of the step motor 51 of the left ventricular linear driving part 50, So that the fluid is pressurized (S4).

When the pressure in the left ventricular cylinder 41 exceeds the opening pressure of the discharge check valve 43 and a pulsating flow is formed, the circulating fluid is discharged through the discharge check valve 43 to the aorta simulating unit 60 ) And the radial artery simulation unit 70 (S5).

At this time, in order to generate a negative pressure effect, the piston 12 in the left atrium cylinder 11 is moved from right to left, and the circulating fluid discharged from the left ventricle cylinder 41 is supplied to the aorta simulating unit 60 and the radial artery simulating unit 70 to the circulating fluid reservoir 14 again.

Therefore, the circulating fluid discharged from the left ventricular cylinder 41 is diverted from the discharge tube 61 of the aorta simulating unit 60 to the descending aorta simulating tube 62 and the radial artery simulating floating inlet 63, and the descending aorta simulating tube The circulating fluid introduced into the radial artery simulation floating inlet 63 flows into the soft tube 71 and transmits a pressure waveform to the user , And then flows into the circulating fluid bath (14) again by the circulation pipe (80) to be circulated.

18, the left ventricle pressure measuring unit 90 measures the pressure in the left ventricle cylinder 41 in real time, and the control unit 110 measures the left ventricle pressure in the left ventricle cylinder 41, And controls the driving of the left ventricular linear driving unit 50 and the left atrium linear driving unit 20 based on the pressure value. In addition, the control unit 110 can adjust the opening pressure of the discharge check valve 43.

The radial artery simulation hydraulic pressure measuring unit 91 measures the pressure of the circulating fluid flowing into the radial artery simulation unit 70 in real time and the display unit measures the pressure of the circulating fluid flowing through the radial artery simulation hydraulic pressure measuring unit 91 And the control unit 110 monitors the pressure waveform to control the driving of the left ventricular linear driving unit 50 and the left atrium linear driving unit 20. [ In addition, the control unit 110 may control the control valve 74 provided at one side of the circulation pipe 80 to adjust the size of the pressure waveform.

Hereinafter, a method of reproducing the artificial pulse wave simulating the sound pressure effect of a real human body will be described. More specifically, a driving method of the left atrium linear driving unit 20 and a driving method of the left ventricular linear driving unit 50 for simulating the sound pressure effect will be described. FIG. 19 is a flowchart illustrating a method for reproducing an artificial pulse wave in consideration of a sound pressure effect according to an embodiment of the present invention.

First, an initial value for generating a pulse wave is set (S10). That is, the solenoid exhaust valve 17 provided at the upper end of the circulating fluid reservoir 14 is opened to drive the step motor 21 of the left atrium linear drive unit 20 in a state where the air pressure in the circulating fluid bath 14 is removed 8) to drive the step motor 51 of the left ventricular linear drive unit 50 to move the piston 12 in the left ventricle cylinder 11 to the left ventricle cylinder (not shown) The solenoid exhaust valve 17 is closed after the piston 44 in the solenoid valve 41 is moved to the correct position (moved to the left end based on the one shown in Fig. 8).

The circulation fluid is circulated in the circulating fluid bath 14 while the piston 12 in the left atrium cylinder 11 is moved forward (from the left side to the right side based on the one shown in Fig. 8) by the driving of the left atrium linear driving unit 20 And flows to the left ventricle cylinder 41 side (S20). The movement of the piston 44 in the left atrium cylinder 11 is continued until the pressure in the left ventricle exceeds a first specified pressure (10 mmHg or more in the specific example) (S30). At this time, the left ventricular pressure measuring unit 90 measures the pressure in the left ventricle in real time, transmits the measured value to the control unit 110, and the control unit 110 feedback-controls the left atrium linear driving unit 20 based on the measured value do.

If the pressure in the left ventricle exceeds a certain pressure, the control unit 110 stops the driving of the left atrium linear driving unit 20 (S40) and prepares the negative pressure effect (S50).

19, the solenoid exhaust valve 17 of the circulating fluid bath 14 is opened, and the left atrium linear driving portion 20 is driven to open the solenoid exhaust valve 17 in the left atrium cylinder 11 (The right end on the basis of the one shown in Fig. 8), and the exhaust valve 17 is closed.

Then, the left ventricular linear drive unit 50 is driven to move the piston 44 in the left ventricle cylinder 41 forward (S60). This driving step is continued until a pulse flow occurs (S70). In this process, the left ventricle pressure measuring unit 90 measures the pressure in the left ventricle in real time, and the control unit 110 controls the left ventricular linear driving unit 50 based on the measured value to adjust the advancing speed of the piston 44 .

When the pressure in the left ventricle exceeds the opening pressure of the discharge check valve 43 while the left ventricular piston 44 advances, the circulating fluid is discharged toward the aortic simulator 60 and the radial artery simulator 70, The controller 110 stops driving the left ventricular linear driving unit 50 (S80).

The control unit 110 drives the left atrium linear driving unit 20 to generate a negative pressure effect by moving the piston 12 in the left atrium cylinder 11 backward to provide a hydraulic pressure to circulate the circulating fluid do.

In other words, as the piston 12 in the left atrium cylinder 11 moves from right to left (backward), the circulating fluid discharged from the left ventricle cylinder 41 flows through the aorta simulating part 60 and the radial artery simulating part 70 Thereby providing a hydraulic pressure that can be circulated back to the circulating fluid reservoir 14.

Therefore, the circulating fluid discharged from the left ventricular cylinder 41 is diverted from the discharge tube 61 of the aorta simulating unit 60 to the descending aorta simulating tube 62 and the radial artery simulating floating inlet 63, and the descending aorta simulating tube The circulating fluid introduced into the radial artery simulation floating inlet 63 flows into the soft tube 71 and transmits a pressure waveform to the user , And then flows into the circulating fluid bath (14) again by the circulation pipe (80) to be circulated.

As the steps S10 to S90 are repeated and repeated, a closed circulating blood supply and circulation system is employed to reproduce a pulse wave.

The present invention can also be embodied as computer-readable codes on a computer-readable recording medium. A computer-readable recording medium includes all kinds of recording apparatuses in which data that can be read by a computer system is stored. Examples of the computer-readable recording medium include a ROM, a RAM, a CD-ROM, a magnetic tape, a floppy disk, an optical data storage device, and the like, and may be implemented in the form of a carrier wave (for example, transmission over the Internet) . In addition, the computer-readable recording medium may be distributed over network-connected computer systems so that computer readable codes can be stored and executed in a distributed manner. In addition, functional programs, codes, and code segments for implementing the present invention can be easily inferred by programmers of the technical field to which the present invention belongs.

It should be noted that the above-described apparatus and method are not limited to the configurations and methods of the embodiments described above, but the embodiments may be modified so that all or some of the embodiments are selectively combined .

1: Conventional pulse wave simulator
2: Model
3: Hydraulic blood flow drive
4: Arterial training wrist instrument
5: Hydraulic blood flow drive system
6: Model Heart
7: Left atrium
8: aortic valve
10: Left atrial contraction
11: Left atrium cylinder
12: Left atrium piston
13: Hose
14: Circulating fluid tank
15: Outlet
16: Inlet
17: Solenoid exhaust valve
19: Inflow pipe
20: Left atrial linear driving part
21: Left atrium step motor
22: Left heart lumbar coupler
23: Left atrium ball screw
25: Left atrial simulator base
26: Left atrium high damper
30: Connector
40: Left ventricle simulator
41: Left ventricular cylinder
42: Insertion check valve
43: Release check valve
44: Left ventricular piston
45: inlet end
46: Discharge end
47: Left ventricular linear drive unit base
48: Left ventricular high damper
49: Low damper
50: Left ventricular linear driving part
51: Left ventricular stepper motor
52: Encoder
53: Left ventricular diatherman coupler
54: Left ventricular ball screw
60: aortic coagulation part
61: discharge pipe
62: Descending descending aorta
63: Radial artery conduit inflow tube
70: Radial artery simulation section
71: Soft tube
72: tube adjuster
73: Support
74: Magnitude adjustment valve
75: Wrist rest pads
80: Circulation tube
90: Left ventricular pressure measuring part
91: Radial artery simulation hydraulic measuring part
100: artificial pulse wave reproduction system
101: Commercial solenoid valve
102: Biomimetic pump
103: Optical iris valve
104: Large iris valve
110:
200: Micro iris valve
210: iris part
211: Adjustable member
212:
220: 1st frame
221: First port
230: second frame
231: Second port
240: Iris driving part

Claims (19)

A device for reproducing an artificial pulse wave,
A left ventricular mimic to produce a pulsatile flow;
A left ventricle simulating unit supplying a circulating fluid to the left ventricle simulating unit and having a closed circulation function; And
And a pulse wave delivery unit that receives the pulse wave delivered by the left ventricular remodeling unit in a pressure waveform,
The pulsatile wave transmission part is branched into an aorta simulation part and a radial artery simulation part,
The circulatory fluid delivered to the left ventricular contraction unit by the left atrial remodeling unit is discharged from the left ventricle simulating unit, a part of the circulating fluid is introduced into the left atrial examining unit via the aortic simulator, the rest is introduced into the radial artery simulating unit, Circulated,
Wherein the left ventricular simulator further comprises a left ventricular cylinder having an inflow end into which the circulating fluid discharged from the left atrial simulation unit flows and a discharge end through which the circulating fluid is discharged by the movement of the piston and a left ventricular linear drive unit for driving the piston, An insertion check valve provided on one side of the inflow end and functioning as a left ventricular diaphragm, and a discharge check valve provided on one side of the inflow end,
Wherein the left atrial simulator includes a circulating fluid water tank having a discharge port through which the circulating fluid is discharged to the left ventricle simulating unit and an inlet through which the circulating fluid discharged from the pulse wave delivering unit flows, A left atrium cylinder for supplying a pneumatic pressure capable of regulating a positive pressure and a negative pressure in the water tank; and an left atrium linear driver for driving the piston in the left atrium cylinder,
A connection tube connecting the outlet of the left atrial simulation section and the inlet end of the left ventricle simulating section; a discharge pipe connecting between the discharge end of the left ventricle simulating part and the pulse wave delivering part; and a descending aorta And a circulation tube for connecting between the radial artery simulation part and the inlet of the left atrial simulation part,
Wherein the radial artery simulation unit comprises a soft tube for transferring a pressure wave by a circulating fluid that is provided between the discharge end and the circulation tube and is discharged from the left ventricle simulating unit.
delete delete The method according to claim 1,
Wherein the discharge check valve is configured as a gauze valve capable of controlling the opening pressure,
Wherein the opening pressure of the discharge check valve is larger than the opening pressure of the insertion check valve.
delete delete The method according to claim 1,
Further comprising a tube adjuster for adjusting at least one of a height and a tension of the transmitting soft tube.
A method for reproducing an artificial pulse wave using the apparatus for reproducing an artificial pulse wave according to claim 1,
The circulating fluid stored in the circulating fluid reservoir of the left atrial simulator is discharged to the connecting pipe by pneumatic pressure;
Introducing the circulating fluid into the left ventricular cylinder of the left ventricular contraction part unidirectionally to the first specific pressure by the insertion check valve;
Moving the piston by the left ventricular linear drive to pressurize the circulating fluid in the left ventricular cylinder;
Wherein the pressure in the left ventricular cylinder exceeds a second specified pressure and forms a pulsating flow and the circulating fluid is discharged through the discharge check valve to the discharge tube;
Receiving a vein flow delivered by the left ventricle simulator in a radial artery simulation pressure waveform; And
Wherein the circulating fluid discharged from the radial artery simulation unit flows into the circulating fluid reservoir through a circulation pipe and circulates through the circulation fluid reservoir.
9. The method of claim 8,
The first specific pressure is at least 1 mmHg to less than 50 mmHg,
Wherein the second specific pressure is greater than or equal to 50 mmHg and less than or equal to 100 mmHg.
10. The method of claim 9,
Wherein the radial artery simulation unit includes a soft tube for transferring a pressure wave by a circulating fluid that is provided between the discharge tube and the circulation tube and is discharged from the left ventricle simulator,
Wherein the tube adjusting part adjusts at least one of a height and a tension of the transmitting soft tube.
delete In the artificial pulse wave reproducing system,
An apparatus for reproducing an artificial pulsating wave according to any one of claims 1, 4, and 7;
A left ventricular pressure measuring unit for measuring in real time the pressure in the left ventricular cylinder, which is a constituent of a left ventricle simulating unit of the apparatus for reproducing the artificial arterial pulse wave; And
And a control unit for controlling the operation of the left ventricular linear driving unit and the left atrial linear driving unit based on the pressure value measured by the left ventricle pressure measuring unit.
13. The method of claim 12,
Wherein the left atrial contraction unit and the left ventricular contraction unit have a dust-proof structure to prevent the residue from being transmitted to the pulse wave transmission unit.
13. The method of claim 12,
A radial artery simulator hydraulic measuring unit for measuring the pressure of the circulating fluid flowing into the radial artery simulation unit in real time;
A display unit for displaying a pressure waveform based on the measurement value measured by the radial artery simulation hydraulic pressure measuring unit; And
And a control valve provided at one side of the circulation tube to adjust the size of the pressure waveform.
A method for reproducing an artificial pulse wave in consideration of the positive pressure and the negative pressure effect of a circulatory fluid tank of a left atrial firing simulator using the artificial pulse wave reproducing system of claim 12,
A first step of opening the exhaust valve of the circulating fluid reservoir and the control unit driving the left atrium linear driving unit and the left ventricular linear driving unit to rearrange the piston in the left atrium cylinder and the piston in the left ventricle cylinder and close the exhaust valve;
The circulating fluid stored in the circulating fluid reservoir of the left atrial simulator is discharged to the connection tube by the positive pressure of the positive pressure and the circulating fluid is discharged to the left ventricle cylinder of the left ventricle simulator by the insertion check valve A second step of flowing into a specific pressure;
A third step of opening the exhaust valve and arranging the piston in the left atrium cylinder forward to prepare a negative pressure effect;
A fourth step of moving the piston in the left ventricular cylinder forward by the left ventricular linear driving unit to pressurize the circulating fluid in the left ventricular cylinder;
A fifth step in which the pressure in the left ventricle cylinder exceeds a second specified pressure and forms a pulsating flow, and the circulating fluid is discharged to the discharging end;
A sixth step in which the piston in the left atrium cylinder is moved backward to generate a negative pressure effect so that the circulating fluid flows into the circulating fluid reservoir through the aortic simulator and the radial artery simulator; And
And a seventh step of repeating the first to sixth steps. The method for reproducing the artificial pulse wave according to the positive pressure and the negative pressure effect.
16. The method of claim 15,
In the second and sixth steps, the control unit feedback-controls the driving of the left atrium linear driving unit based on the pressure value measured by the left ventricular pressure measuring unit,
Wherein the control unit feedback-controls the driving of the left ventricular linear driving unit based on the pressure value measured by the left ventricle pressure measuring unit in the fourth and fifth steps.
17. The method of claim 16,
Wherein the control unit controls the movement speed of the piston of the left ventricular linear driving unit based on the measured pressure value to generate a waveform of a specific pressure, wherein the positive pressure and the negative pressure effect are considered.
18. The method of claim 17,
Controlling the opening pressure of the discharge check valve by the control unit;
Measuring the pressure of the circulating fluid flowing into the radial artery simulation section in real time;
The display unit displaying the pressure waveform based on the measured value measured by the radial artery simulator hydraulic pressure measuring unit; And
Controlling the size of the pressure waveform by controlling the control valve provided at one side of the circulation pipe; Wherein the at least one of the at least one of the at least one of the at least two of the at least two of the at least two of the at least one of the at least two of the at least one of the at least two of the at least one of the at least one of
delete

Images