CN203376337U - Full-automatic biochip microarrayer - Google Patents
Full-automatic biochip microarrayer Download PDFInfo
- Publication number
- CN203376337U CN203376337U CN201320418661.7U CN201320418661U CN203376337U CN 203376337 U CN203376337 U CN 203376337U CN 201320418661 U CN201320418661 U CN 201320418661U CN 203376337 U CN203376337 U CN 203376337U
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- film carrier
- platform
- arraying
- micro
- electromagnetic valve
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Abstract
The utility model discloses a full-automatic biochip microarrayer. The full-automatic biochip microarrayer is characterized by comprising a main engine, a three-axis movement platform, an injection pump, a mini-type solenoid valve, a micro-arraying needle, a micro-arraying platform, a film carrying platform, a touchable screen monitor and a camera. The full-automatic biochip microarrayer has the following advantages that full-automatic micro-arraying is realized; one microarrayer is provided with one micro-arraying needle and one micro-arraying needle is used for micro-arraying one sample; the micro-arraying needle is easy to wash and cross infection is avoided; the camera is used for monitoring the whole micro-arraying process and an alarm is sent as soon as leaked micro-arraying and wrong micro-arraying are founded so as to ensure the micro-arraying quality; a film carrying plate is movable, replaceable and detachable so that a chip is very convenient to mount and detach.
Description
Technical field
The utility model relates to biological field, specifically a kind of full-automatic biological chips point sample instrument.
Background technology
Biochip technology is exactly after a large amount of probe molecules being fixed on solid support by micro fabrication simultaneously and the sample molecule of mark is hybridized, by the hybridization signal intensity that detects each probe molecule and then the quantity of obtaining sample molecule and sequence information and understand efficiently and analyze.Mostly the probe point sample is to coordinate apparatus control with manual operations at present, can't realize the full automation point sample; And the film carrier platform of current existing point sample instrument is all to be fixed on sample application platform, irremovable, non-exchange, non-disconnectable removing, dress is got the chip inconvenience; With a point sample instrument, a plurality of spotting needles are arranged, a multiple sample of point sample pin mark, clean difficulty, easily cross-infection.
Summary of the invention
For addressing the above problem, the utility model provides a kind of full-automatic biological chips point sample instrument.
A kind of full-automatic biological chips point sample instrument, is characterized in that, but comprise main frame, triaxial movement platform, syringe pump, miniature electromagnetic valve, spotting needle, sample application platform, film carrier platform touch screen monitor and camera:
---described sample application platform is as frame, but triaxial movement platform, miniature electromagnetic valve, film carrier platform touch screen monitor and camera are arranged on sample application platform;
---but described main frame is connected respectively with triaxial movement platform, syringe pump, miniature electromagnetic valve touch screen monitor, camera, control triaxial movement platform, syringe pump and miniature electromagnetic valve work, process the various information that camera returns, but process the various touch orders of touch screen monitor;
---described syringe pump is arranged on sample application platform or triaxial movement platform, syringe pump is connected with miniature electromagnetic valve by woven hose, miniature electromagnetic valve is connected with spotting needle, and syringe pump is passed to miniature electromagnetic valve by probe, and miniature electromagnetic valve is passed to probe spotting needle again and carries out point sample;
---described spotting needle is arranged on triaxial movement platform, drives spotting needle by the host computer control triaxial movement platform and moves, and stop at assigned address;
---described film carrier platform is for placing biochip;
---but described touch screen monitor provides man-machine interface, by software control, puts membrane process;
---described camera head monitor point membrane process, and information is fed back to main frame.
Said structure setting of the present utility model can realize full-automatic point sample, but carry out policer operation by camera and touch screen monitor, but the signal transmitted according to the touch screen monitor by main frame again, send instruction by main frame, controlling triaxial movement platform drive spotting needle moves on biochip, syringe pump is passed to miniature electromagnetic valve by probe, and miniature electromagnetic valve is passed to probe spotting needle again and carries out point sample.
Described film carrier platform is the movable belt magnetic-type, comprises the square bearing of the end opening be comprised of left socle, right support and after-poppet, and the left and right support is provided with guide rail, and after-poppet is provided with phase magnet; Also comprise the film carrier plate, the guide rail of the corresponding left and right of film carrier plate support is provided with slide block, and corresponding both sides or the surrounding of film carrier plate are provided with press mold magnet, and on press mold magnet, magnetic has the press mold bar, and corresponding phase magnet place, film carrier plate top is provided with the location suction block.
Described film carrier plate end can arrange carriage as required, is convenient to hand-held extraction film carrier plate.
Described square bearing and film carrier plate are made by aluminium alloy, and press mold bar and location suction block are that ferromagnetic material is made (as metals such as iron, nickel, cobalts).
Described guide rail is at the inboard spill chute arranged of left and right support.
When film carrier platform of the present utility model adopts the movable belt magnetic-type to use, can be fixedly mounted on sample application platform, then the slide block correspondence of film carrier plate is pushed to the guide rail of left and right support, until the location suction block of film carrier plate is fixing to locate with the phase magnet phase magnetic of after-poppet; Again the press mold bar on the film carrier plate is picked up, biochip is layed on the film carrier plate, compress biochip (or elder generation is laid on biochip above the film carrier plate before back(ing) board pushes the left and right support guide, the film carrier plate is pushed in the support guide of left and right after the press mold bar is fixing again) with the press mold bar by the magnetic with press mold magnet; Then carry out point sample, point sample is complete extracts the film carrier plate out, pushes the square bearing of another film carrier platform, carries out in addition point sample.
Movable belt magnetic-type film carrier platform is by the structure setting of film carrier plate and bearing, the film carrier plate can be realized replaceable, removable, many places magnet makes back(ing) board band magnetic force, both can be used for location, be convenient to the point sample operation, can adopt again press mold bar fixed biologically chip, make dress get chip all very convenient.And movable belt magnetic-type film carrier platform makes the flowing water point sample become possibility, many point sample instruments can be set, form the point sample production line, a film carrier platform only is installed on every point sample instrument, each film carrier platform is only put a sample, by with the successively point sample of film carrier plate on different film carrier platforms, make same biochip on the film carrier plate can detect a plurality of samples, and can not produce cross-infection.
The utlity model has following advantage: 1. realize the full automation point sample; 2. spotting needle of a point sample instrument, an a kind of sample of point sample pin mark, spotting needle easily cleans, and avoids cross-infection; 3. camera head monitor point sample whole process, find leak source, the warning immediately of wrong point, guarantees the point sample quality; 4. back(ing) board is removable, replaceable, dismountable, and it is all very convenient that dress is got chip.
The accompanying drawing explanation
The theory diagram that Fig. 1 is embodiment 1.
The structural representation that Fig. 2 is embodiment 1 product.
The film carrier platform structure schematic diagram (not placing the press mold bar) that Fig. 3 is embodiment 2.
Fig. 4 removes the schematic diagram of film carrier plate in Fig. 3.
The schematic diagram that Fig. 5 is the film carrier plate.
The A-A cut-open view that Fig. 6 is Fig. 3.
The B-B cut-open view that Fig. 7 is Fig. 3.
Fig. 8 is the structural representation that Fig. 6 places press mold bar and biochip.
Description of reference numerals: 1---main frame; 2---triaxial movement platform; 3---syringe pump; 4---miniature electromagnetic valve; 5---spotting needle; 6---sample application platform; 7---the film carrier platform; But 8---the touch screen monitor; 9---camera; 10---biochip; 11---left socle; 12---right support; 13---after-poppet; 14---guide rail; 15---phase magnet; 16---the film carrier plate; 17---slide block; 18---press mold magnet; 19---the press mold bar; 20---the location suction block; 21---carriage.
Embodiment
Embodiment 1: as shown in Fig. 1～2, the full-automatic biological chips point sample instrument, is characterized in that, but comprise main frame, triaxial movement platform, syringe pump, miniature electromagnetic valve, spotting needle, sample application platform, film carrier platform touch screen monitor and camera:
---described sample application platform is as frame, but triaxial movement platform, miniature electromagnetic valve, film carrier platform touch screen monitor and camera are arranged on sample application platform;
---but described main frame is connected respectively with triaxial movement platform, syringe pump, miniature electromagnetic valve touch screen monitor, camera, control triaxial movement platform, syringe pump and miniature electromagnetic valve work, process the various information that camera returns, but process the various touch orders of touch screen monitor;
---described syringe pump is arranged on sample application platform or triaxial movement platform, syringe pump is connected with miniature electromagnetic valve by woven hose, miniature electromagnetic valve is connected with spotting needle, and syringe pump is passed to miniature electromagnetic valve by probe, and miniature electromagnetic valve is passed to probe spotting needle again and carries out point sample;
---described spotting needle is arranged on triaxial movement platform, drives spotting needle by the host computer control triaxial movement platform and moves, and stop at assigned address;
---described film carrier platform is for placing biochip;
---but described touch screen monitor provides man-machine interface, by software control, puts membrane process;
---described camera head monitor point membrane process, and information is fed back to main frame.
Embodiment 2: as shown in Fig. 3～8, as different from Example 1, described film carrier platform is the movable belt magnetic-type, the square bearing that comprises the end opening formed by left socle, right support and after-poppet, the left and right support is provided with guide rail, guide rail is that after-poppet is provided with phase magnet at the inboard spill chute arranged of left and right support; Also comprise the film carrier plate, the guide rail of the corresponding left and right of film carrier plate support is provided with slide block, and the left and right sides of film carrier plate is provided with press mold magnet, and on press mold magnet, magnetic has the press mold bar, and corresponding phase magnet place, film carrier plate top is provided with the location suction block, and film carrier plate end is provided with carriage.
Claims (2)
1. a full-automatic biological chips point sample instrument, is characterized in that, but comprise main frame, triaxial movement platform, syringe pump, miniature electromagnetic valve, spotting needle, sample application platform, film carrier platform touch screen monitor and camera:
---described sample application platform is as frame, but triaxial movement platform, miniature electromagnetic valve, film carrier platform touch screen monitor and camera are arranged on sample application platform;
---but described main frame is connected respectively with triaxial movement platform, syringe pump, miniature electromagnetic valve touch screen monitor, camera, control triaxial movement platform, syringe pump and miniature electromagnetic valve work, process the various information that camera returns, but process the various touch orders of touch screen monitor;
---described syringe pump is arranged on sample application platform or triaxial movement platform, syringe pump is connected with miniature electromagnetic valve by woven hose, miniature electromagnetic valve is connected with spotting needle, and syringe pump is passed to miniature electromagnetic valve by probe, and miniature electromagnetic valve is passed to probe spotting needle again and carries out point sample;
---described spotting needle is arranged on triaxial movement platform, drives spotting needle by the host computer control triaxial movement platform and moves, and stop at assigned address;
---described film carrier platform is for placing biochip;
---but described touch screen monitor provides man-machine interface;
---described camera head monitor point membrane process, and information is fed back to main frame.
2. point sample instrument according to claim 1, is characterized in that, described film carrier platform is the movable belt magnetic-type, comprises the square bearing of the end opening be comprised of left socle, right support and after-poppet, and the left and right support is provided with guide rail, and after-poppet is provided with phase magnet; Also comprise the film carrier plate, the guide rail of the corresponding left and right of film carrier plate support is provided with slide block, and corresponding both sides or the surrounding of film carrier plate are provided with press mold magnet, and on press mold magnet, magnetic has the press mold bar, and corresponding phase magnet place, film carrier plate top is provided with the location suction block.
3. point sample instrument according to claim 2, is characterized in that, described film carrier plate end is provided with carriage.
4. point sample instrument according to claim 2, is characterized in that, described square bearing and film carrier plate are made by aluminium alloy, and press mold bar and location suction block are that ferromagnetic material is made.
5. point sample instrument according to claim 2, is characterized in that, described guide rail is at the inboard spill chute arranged of left and right support.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320418661.7U CN203376337U (en) | 2013-07-15 | 2013-07-15 | Full-automatic biochip microarrayer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320418661.7U CN203376337U (en) | 2013-07-15 | 2013-07-15 | Full-automatic biochip microarrayer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203376337U true CN203376337U (en) | 2014-01-01 |
Family
ID=49838860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320418661.7U Withdrawn - After Issue CN203376337U (en) | 2013-07-15 | 2013-07-15 | Full-automatic biochip microarrayer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203376337U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103412135A (en) * | 2013-07-15 | 2013-11-27 | 广东凯普生物科技股份有限公司 | Full-automatic biochip sample applicator |
| CN104965047A (en) * | 2014-10-13 | 2015-10-07 | 中国药科大学 | Novel planar chromatography sample application instrument and step repeated sample application method |
| CN106168626A (en) * | 2016-04-08 | 2016-11-30 | 深圳雷杜生命科学股份有限公司 | Biochip analysis instrument and the method for analysis |
| CN110082473A (en) * | 2019-05-16 | 2019-08-02 | 广州市鹭江远科技有限公司 | A kind of spot sample device for aflatoxins detection based on thin layer chromatography |
-
2013
- 2013-07-15 CN CN201320418661.7U patent/CN203376337U/en not_active Withdrawn - After Issue
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103412135A (en) * | 2013-07-15 | 2013-11-27 | 广东凯普生物科技股份有限公司 | Full-automatic biochip sample applicator |
| CN103412135B (en) * | 2013-07-15 | 2014-11-26 | 广东凯普生物科技股份有限公司 | Full-automatic biochip sample applicator |
| CN104965047A (en) * | 2014-10-13 | 2015-10-07 | 中国药科大学 | Novel planar chromatography sample application instrument and step repeated sample application method |
| CN106168626A (en) * | 2016-04-08 | 2016-11-30 | 深圳雷杜生命科学股份有限公司 | Biochip analysis instrument and the method for analysis |
| CN110082473A (en) * | 2019-05-16 | 2019-08-02 | 广州市鹭江远科技有限公司 | A kind of spot sample device for aflatoxins detection based on thin layer chromatography |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20140101 Effective date of abandoning: 20141126 |
|
| AV01 | Patent right actively abandoned |
Granted publication date: 20140101 Effective date of abandoning: 20141126 |
|
| RGAV | Abandon patent right to avoid regrant |