CN203369959U - Multi-electrode hypertension intravascular treatment catheter capable of adjusting impedance - Google Patents

Multi-electrode hypertension intravascular treatment catheter capable of adjusting impedance Download PDF

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Publication number
CN203369959U
CN203369959U CN201320363504.0U CN201320363504U CN203369959U CN 203369959 U CN203369959 U CN 203369959U CN 201320363504 U CN201320363504 U CN 201320363504U CN 203369959 U CN203369959 U CN 203369959U
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China
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electrode
joystick
catheter
hypertension
blood vessel
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CN201320363504.0U
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Inventor
曾延华
方唯一
曲新凯
彭文涛
周怀其
黄柯
李明
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HUNAN EVD MEDICAL DEVICE CO Ltd
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HUNAN EVD MEDICAL DEVICE CO Ltd
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Abstract

The utility model relates to a multi-electrode hypertension intravascular treatment catheter capable of adjusting impedance. The multi-electrode hypertension intravascular treatment catheter comprises a catheter body, a control handle, a connection plug and multiple electrodes. One end of the catheter body is connected with the connection plug, the control handle is arranged at the end, close to the connection plug, of the catheter body, and an electrode framework is arranged at the end, away from the connection plug, of the catheter body. The electrodes are assembled on the electrode framework, a fixed electrode front joint is formed at the end, away from the control handle, of the electrode framework, and a slidable electrode rear joint is formed at the end, close to the control handle, of the electrode framework. A dragging wire dragging the electrode framework is arranged in a cavity of the catheter body, and an adjusting portion adjusting the dragging wire is arranged on the control handle. One end of the dragging wire is fixed on the electrode front joint, and the other end of the dragging wire penetrates through the electrode rear joint and is fixed on the adjusting portion of the control handle. According to the multi-electrode hypertension intravascular treatment catheter capable of adjusting impedance, the dragging wire is used for adjusting and controlling outward expansion of the electrode framework, the attaching force of the electrodes on the electrode framework and the wall of the renal artery vessel is changed, and therefore the multi-electrode hypertension intravascular treatment catheter can be more tightly attached to the blood vessel so as to adjust impedance.

Description

The hypertension blood vessel internal treatment catheter of multipole adjustable impedance
Technical field
The present invention relates to a kind of hypertensive conduit of clinical treatment that is applied to, particularly relate to a kind of hypertension blood vessel internal treatment catheter of multipole adjustable impedance.
Background technology
Hypertension is to have a strong impact on people's life quality and life-threatening common disease, is also that the whole world causes dead Etiological, and the annual whole world 7 million peoples are because of hypertension death.The recent year Epidemiological study shows, men and women's prevalence all surpasses more than 20%, China is one of the most serious country of hypertension harm in the world at present, estimate that national hyperpietic surpasses 200,000,000, in international coverage, the whole world has 1,000,000,000 people to suffer from hypertension at present, and expecting hyperpietic in 2025 will have 30% people to suffer from hypertension, and sum reaches 1,500,000,000.As can be seen here, hypertension has become that global range comprises that the current prevalence of China is the highest, one of the ill the most general disease of crowd, and the research of hypertensive research and new treatment becomes the instant problem of the mankind.
The serious consequence that hyperpietic's blood pressure increases is the infringement to the whole body vitals, easily cause the most serious complication of infringement of the hearts such as coronary heart disease, apoplexy, renal failure, brain, kidney, thereby the disability rate that it is caused and mortality rate obviously increases.
Popular hypertension therapeutic remains Drug therapy both at home and abroad at present.On Therapeutic Method, be mainly to rely on medicine, wherein of greatest concern and what play a major role is calcium channel blocker, angiotensin-convertion enzyme inhibitor and angiotensin ii receptor antagonist, and after outstanding, two class medicines are main, and the effect of these rear two class medicines is all in renin-angiotensin system.The treatment of the Long term combined medication of such medicine, will not only need long-term taking and expensive, side effect outstanding, most importantly therapeutic effect is still undesirable.Data shows that the current hypertensive treatment rate of China and control rate are only 24.7% and 6.1%.Therefore, the condition of medicine treatment for hypertension that generally believes global range still because side effect is more, individual variation, control rate be not still good, because the mortality rate that hypertension causes can be in any more.
The basic cause of essential hypertension is because the sympathetic nerve overacfivity brings out and maintains.The radiolabel demonstration, the hyperpietic exists the too much noradrenaline secretion of kidney and enters blood system.After the sympathetic ganglion of domination kidney, nerve is arranged all blood vessel, renal tubules and juxtaglomerular apparatuses in kidney after entering kidney, thereby renin angiotensin aldosterone system is regulated, conversely, Angiotensin II can increase again adrenal gland's energy neurotransmission of central mechanism and acceleration SNE.So, orthosympathetic effect causes blood pressure to increase.Thereby generally believe at present, the orthosympathetic activity of kidney is the major reason that causes essential hypertension.
External zoopery and clinical experiment confirm: blocking-up kidney sympathetic nerve, not only can not cause that the kidney normal function lowers, and can make systolic pressure and diastole all descend, this explanation, although essential hypertension has multifactor existence, the orthosympathetic activity of domination kidney and tension force are to play an important role in hypertension existence and progress.The surgery wide excision visceral nerve operation of previously once carrying out, can reduce renin secretion, do not reduce the filtration rate of kidney blood flow and glomerule, still can maintain electrolytical balance.But the operation of visceral nerve blocking-up has so widely caused the complication of very high peri-operation period, and the sickness rate of lacking of proper care of other viscera functions after removing are also very high because of visceral nerve widely.The kidney transfer operation of at present clinical more enforcement can illustrate well, and after removing the kidney nerve, kidney still can keep the stable of power and water solution matter.In zoopery, also observe, when hypertension, the sympathetic nervous system of kidney and body is closely related.Therefore, if optionally in one organ level blocking-up renin-angiotensin system, can interrupt the hypertensive effect of liter of renin-angiotensin system, simultaneously, reduction due to the renin-angiotensin system vaso-active substance, it is also weakened the orthosympathetic activation effect of whole body, thereby, keeping under the prerequisite that renal function is complete that systemic blood pressure is descended, reaches the hypertensive purpose for the treatment of.Be that super-selective blocking-up kidney sympathetic nerve will make blood pressure drops, can avoid other unnecessary impacts on bodily tissue and organ simultaneously.Our company is being devoted to this research always, and the Related products such as the interior radiofrequency ablation therapy conduit of multipole hypertension blood vessel have also been developed, in order to ensure better in clinical use that in art radio frequency is disposed the time, radio frequency output can maintain best output state, reach the purpose of regulating impedance, the spy has carried out many improvement.
Summary of the invention
In order to solve the problems of the technologies described above, the invention provides a kind of multipole scalable catheter electrode and blood vessel and attach, regulate the hypertension blood vessel internal treatment catheter of impedance.Its technical scheme is: a kind of hypertension blood vessel internal treatment catheter of multipole adjustable impedance, comprise catheter tube, joystick, connecting pin and a plurality of electrode, one end of described catheter tube is connected with described connecting pin, and be provided with joystick at the end by connecting pin, described catheter tube is provided with electrode skeleton away from an end of connecting pin, described a plurality of electrode is assemblied on electrode skeleton, before forming fixing electrode away from the joystick end, electrode skeleton combines, form slidably and combine after electrode by the joystick end at electrode skeleton, the drawing silk that the described electrode skeleton of tractive is arranged in the tube chamber of described catheter tube, the adjusting part of regulating described drawing silk is arranged on described joystick, one end of described drawing silk is combined before being fixed on described electrode, the other end of drawing silk is combined after passing described electrode, be fixed on the adjusting part of described joystick.
Adjusting portion on above-mentioned joystick is divided and is comprised spiral rotary button bar and tractive adjusting knob, described spiral rotary knob rod is with external screw thread, be linked in the tractive adjusting knob with female thread, the fixed position of described drawing silk on joystick is the front end of spiral rotary knob rod.
Above-mentioned a plurality of electrode cross-section, by ring 360 degree uniform distributions, distributes before and after longitudinal surface is.
Above-mentioned electrode is 3, and the angle between electrode cross-section is 120 degree.
Above-mentioned electrode is 6, and the angle between electrode cross-section is 60 degree.
Be provided with the wire of impedance measuring, temperature measuring and radio frequency output in the tube chamber of above-mentioned catheter tube, one of the wire of impedance measuring, temperature measuring and radio frequency output terminates to connecting pin, and the other end is received on electrode through the endoceliac output input lead of catheter tube.
Above-mentioned catheter tube is divided into the leading portion body near the back segment body of joystick and close electrode, and the back segment body adopts the polymer of high rigidity, and leading portion adopts the low polymeric material of hardness number, and heat fuses and connects two sections.
Above-mentioned drawing silk adopts has elastic tinsel making.
The present invention adopts joystick, is convenient to propelling movement, tractive or rotation, with regulate that conduit moves in blood vessel and towards; But the drawing silk of tractive electrode skeleton is set in catheter tube, the drawing silk of adjusting on joystick part in can the tractive catheter tube, can change the outer swollen power of electrode skeleton, thereby the electrode and the renal artery tube wall that change on body front end electrode skeleton attach power, make it attach blood vessel tighter, regulate impedance; The present invention is mainly used in Bilateral Renal sympatholytic, and the effect that the blocking-up sympathetic nerve excites kidney to produce and secretes feritin-angiotensin, make blood pressure drops; But this conduit is monitored renal artery vascular tissue temperature, is measured the function of renal artery tissue local impedance in art, and it is organized anti-regulatory function and can ensure when in art, radio frequency is disposed, and radio frequency output can maintain best output state; Its multipole configuration is the sympatheticoparalytic effect of enhancing ring renal artery and safety better.
The accompanying drawing explanation.
The overall structure schematic diagram of the hypertension blood vessel internal treatment catheter that Fig. 1 is swelling multipole adjustable impedance of the present invention.
The front segment structure schematic diagram of the hypertension blood vessel internal treatment catheter that Fig. 2 is not swelling multipole adjustable impedance of the present invention.
The rear section structure schematic diagram of the hypertension blood vessel internal treatment catheter that Fig. 3 is multipole adjustable impedance of the present invention.
Fig. 4 is after drawing silk of the present invention is subject to tractive, the outer swollen internal structure schematic diagram of electrode skeleton.
Fig. 5 is the outer swollen structural representation of electrode skeleton of the present invention.
Fig. 6 be multiple electrode catheter of the present invention when transverse section, electrode is at the distribution situation figure of blood vessel.
Fig. 7 be multiple electrode catheter of the present invention when longitudinal surface, electrode is at the distribution situation figure of blood vessel.
In figure: combine 5-leading portion body 6-drawing silk 7-back segment body 8-before 1-electrode 2-electrode skeleton 3-electrode after associating 4-electrode and manage endoceliac output input lead 9-spiral rotary knob rod 10-tractive adjusting knob 11-connecting pin 12-catheter tube 13-joystick.
The specific embodiment:
Referring to accompanying drawing, the present invention includes catheter tube 12, joystick 13, connecting pin 11 and a plurality of electrode 1, one end of described catheter tube 12 is connected with described connecting pin 11, and be provided with joystick 13 at the end by connecting pin 11, described catheter tube 12 is provided with electrode skeleton 2 away from an end of connecting pin 11, a plurality of electrodes 1 are assemblied on electrode skeleton 2, before forming fixing electrode away from joystick 13 ends, electrode skeleton 2 combines 3, form slidably and combine 4 after electrode by joystick 13 ends at electrode skeleton 2, the drawing silk 6 that the described electrode skeleton of tractive is arranged in the tube chamber of described catheter tube 12, the adjusting part 9 of regulating described drawing silk is arranged on described joystick 13, 10, drawing silk 6 adopts the tinsel with favorable elasticity to make, the one end combines 3 before being welded on fixing electrode, the other end of drawing silk 6 passes electrode skeleton 2 and slidably after electrode, combines 4, be fixed on the adjusting part 9 of described joystick, 10.
As accompanying drawing 3, 4, shown in 5, adjusting portion on the joystick of the present embodiment is divided and is comprised spiral rotary button bar 9 and tractive adjusting knob 10, one end of drawing silk combines 3 before being fixed on electrode, the other end is combined the front end that is fixed on the spiral rotary knob rod 9 on joystick after 4 after passing described electrode, spiral rotary knob rod 9 is with external screw thread, be linked in the tractive adjusting knob 10 with female thread, the tractive adjusting knob 10 that is positioned at outside is fixed, when rotating tractive adjusting turn-knob 10 outward, with regard to being pulled, tractive drawing silk 6 reaches the effect of retraction to the spiral rotary knob rod 9 of helical screw sample of the inside, thereby electrode skeleton 2 is expanded, attach blood vessel tighter, when when the counter-rotation tractive adjusting knob 10, the spiral rotary knob rod 9 of the inside is released, thereby discharges drawing silk 6 tension force, reaches and adjusts electrode skeleton 2, controls the outer swollen power of skeleton, regulates the effect that electrode 1 and blood vessel attach degree.Adjusting on joystick 13 part can also comprise other modes, such as bite type etc.
The body of this conduit can adopt tinsel strengthening net composite plastic to make, the catheter tube front end is multielectrode signal of telecommunication output and collecting part, and the output input lead of the input and output of electrode signal in catheter tube and in joystick is connected to the connecting pin at body rear portion.
Shown in accompanying drawing 6,7, electrode skeleton 2 employing NiTi flat filaments are made, and a plurality of electrode cross-sections on it, by ring 360 degree uniform distributions, vertically are each electrode front and back and distribute.Electrode is 3, and the angle between electrode cross-section is 120 degree.Electrode also can be 6, and the angle between electrode cross-section is 60 degree.
Shown in accompanying drawing 1,3, each electrode all disposes temperature measuring, impedance measuring and radio frequency output and loads.
Termination electrode is made by platinum, platinumiridio, silver or other metals with excellent conductive performance, and thermal resistor wire, radio frequency output lead, impedance measuring wire can adopt the wire producing with insulating properties.One end of the wire of impedance measuring is welded on termination electrode, then the NiTi flat filament skeleton 2 by electrode, through the endoceliac output input lead 8 of the pipe of catheter tube and joystick, finally be welded in connecting pin 11.One end of each thermal resistor wire is fixed in termination electrode, then by electrode skeleton 2, finally be welded in connecting pin 11 through the endoceliac output input lead 8 of the pipe of catheter tube and joystick.One end of radio frequency output lead is welded on termination electrode, then by electrode skeleton 2, finally be welded in connecting pin 11 through the endoceliac output input lead 8 of the pipe of catheter tube and joystick.
As accompanying drawing 2, shown in 3, catheter tube is divided into the leading portion body 5 near the back segment body 7 of joystick and close electrode, back segment body 7 adopts the polymer of high rigidity to make, and quality is harder, convenient operation, leading portion body 5 adopts the low polymeric material of hardness number, quality is softer, is convenient to bending, and heat fuses two sections bodys of connection and gets final product.
The method that this conduit percutaneous puncture Wicresoft gets involved, the intravascular intracavity arrives renal artery, when impedance is suitable, the bilateral renal arteries tube wall is imposed to the high frequency current in short bursts, sympathetic nerve on the renal artery wall is destroyed, and sympathetic nerve interrupts for the domination of kidney, and feritin-angiotensin is reduced for a long time, thereby blood pressure drops, reach the hypertensive effect for the treatment of.
Experiment in animal body: after femoral arteriography has been put hemostatic catheter, send the 8F guiding catheter through this hemostatic catheter, the front end that x-ray DSA observes lower confirmation guiding catheter arrives in renal artery, then, hypertension blood vessel internal treatment catheter is sent into through the 8F guiding catheter, under x-ray DSA observes, notice that termination electrode arrives the renal artery proper site.Jointing, to radiofrequency generator, is handled the tractive button, makes the catheter end electrode attach the renal artery inwall, measures the impedance of renal artery inwall, and adjusting and setting impedance is 100 Europe mothers, and 80 volts of voltages, be 50 seconds between power 30 watt-hours; Measure renal artery place temperature and impedance.To the renal artery circle, at interval, 120 degree places implement to melt.One side completes the endarterial same operation of contralateral kidney after finishing then.After finish both sides, radiofrequency catheter exits, and via guide wire, exits externally, and local point of puncture hemostasis wrapping finishes operation.Hypertension blood vessel internal treatment catheter is collected and exited guiding catheter, withdraw from hemostatic catheter, point of puncture compressing blood.

Claims (8)

1. the hypertension blood vessel internal treatment catheter of a multipole adjustable impedance, comprise catheter tube (12), joystick (13), connecting pin (11) and a plurality of electrode (1), one end of described catheter tube (12) is connected with described connecting pin (11), and be provided with joystick (13) at the end by connecting pin (11), it is characterized in that: described catheter tube (12) is provided with electrode skeleton (2) away from an end of connecting pin, described a plurality of electrode (1) is assemblied on electrode skeleton (2), associating (3) before electrode skeleton forms fixing electrode away from joystick (13) end, form slidably and combine (4) after electrode by joystick (13) end at electrode skeleton (2), the drawing silk (6) that the described electrode skeleton of tractive (2) is arranged in the tube chamber of described catheter tube (12), the adjusting part (9 of regulating described drawing silk (6) is arranged on described joystick (13), 10), one end of described drawing silk (6) is combined (3) before being fixed on described electrode, the other end of drawing silk (6) is combined (4) after passing described electrode, be fixed on the adjusting part of described joystick (13).
2. the hypertension blood vessel internal treatment catheter of multipole adjustable impedance according to claim 1, it is characterized in that: the adjusting portion on described joystick is divided and is comprised spiral rotary button bar (9) and tractive adjusting knob (10), described spiral rotary knob rod (9) is with external screw thread, be linked in the tractive adjusting knob (10) with female thread, the fixed position of described drawing silk on joystick is the front end of spiral rotary knob rod (9).
3. the hypertension blood vessel internal treatment catheter of multipole adjustable impedance according to claim 1 is characterized in that: described a plurality of electrode cross-sections, by ring 360 degree uniform distributions, distribute before and after longitudinal surface is.
4. the hypertension blood vessel internal treatment catheter of multipole adjustable impedance according to claim 1, it is characterized in that: described electrode is 3, the angle between electrode cross-section is 120 degree.
5. the hypertension blood vessel internal treatment catheter of multipole adjustable impedance according to claim 1, it is characterized in that: described electrode is 6, the angle between electrode cross-section is 60 degree.
6. the hypertension blood vessel internal treatment catheter of multipole adjustable impedance according to claim 1, it is characterized in that: the wire that is provided with impedance measuring, temperature measuring and radio frequency output in the tube chamber of described catheter tube, one of the wire of impedance measuring, temperature measuring and radio frequency output terminates to connecting pin (11), and the other end is in the endoceliac output input lead of catheter tube (8) is received electrode (1).
7. the hypertension blood vessel internal treatment catheter of multipole adjustable impedance according to claim 1, it is characterized in that: described catheter tube is divided into the leading portion body (5) near the back segment body (7) of joystick and close electrode, back segment body (7) adopts the polymer of high rigidity, leading portion body (5) adopts the low polymeric material of hardness number, and heat fuses and connects two sections bodys.
8. the hypertension blood vessel internal treatment catheter of multipole adjustable impedance according to claim 1 is characterized in that: described drawing silk adopts to have elastic tinsel and makes.
CN201320363504.0U 2013-06-24 2013-06-24 Multi-electrode hypertension intravascular treatment catheter capable of adjusting impedance Expired - Lifetime CN203369959U (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104287824A (en) * 2014-10-11 2015-01-21 先健科技(深圳)有限公司 Ablation catheter device
CN105193498A (en) * 2015-09-18 2015-12-30 先健科技(深圳)有限公司 Ablation catheter device
CN106963486A (en) * 2017-05-20 2017-07-21 王新 A kind of esophageal regurgitation radio-frequency ablation electrode
CN107174336A (en) * 2017-05-20 2017-09-19 王新 A kind of esophageal regurgitation radio-frequency ablation electrode

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104287824A (en) * 2014-10-11 2015-01-21 先健科技(深圳)有限公司 Ablation catheter device
WO2016055000A1 (en) * 2014-10-11 2016-04-14 先健科技(深圳)有限公司 Ablation catheter device
CN105193498A (en) * 2015-09-18 2015-12-30 先健科技(深圳)有限公司 Ablation catheter device
CN106963486A (en) * 2017-05-20 2017-07-21 王新 A kind of esophageal regurgitation radio-frequency ablation electrode
CN107174336A (en) * 2017-05-20 2017-09-19 王新 A kind of esophageal regurgitation radio-frequency ablation electrode

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