CN106901831A - The arteria renalis stimulates ablating electrode conduit - Google Patents
The arteria renalis stimulates ablating electrode conduit Download PDFInfo
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- CN106901831A CN106901831A CN201710176340.3A CN201710176340A CN106901831A CN 106901831 A CN106901831 A CN 106901831A CN 201710176340 A CN201710176340 A CN 201710176340A CN 106901831 A CN106901831 A CN 106901831A
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- arteria renalis
- basket
- stimulates
- core
- distal end
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
- A61B2018/00267—Expandable means emitting energy, e.g. by elements carried thereon having a basket shaped structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
- A61B2018/00279—Anchoring means for temporary attachment of a device to tissue deployable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00434—Neural system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00505—Urinary tract
- A61B2018/00511—Kidney
Abstract
A kind of electrode catheter that rapidly and accurately sympathetic nerve on arteria renalis wall is stimulated and melted using same conduit.Its by the conductive filament head in the leading electrode conduit insertion arteria renalis, can adapt to arteria renalis inwall fully and be in close contact and renal sympathetic nerve therein stimulated and control handle that the basket of ablative surgery, pipe shaft, control basket spatial form change and the ring electrode on basket electrically connected with external stimulation instrument and radiofrequency generator and the connector of the control handle afterbody is fixed on be constituted by changing spatial form.It can carry out electro photoluminescence to arteria renalis inner membrance, and mapping causes the significantly raised point position of blood pressure, finds sympathetic nerve close quarters to because of stimulation, carry out positioning target spot ablation, the sympathetic nerve on significantly more efficient ablation arteria renalis wall.It can be realized for the stimulation mapping of the arteria renalis, ablation, temperature control in being completed on same ring electrode, it is to avoid site error caused by the various process various apparatuses of replacing, more accurately, fast.
Description
Technical field
The present invention relates to a kind of medicine equipment of PCI, particularly a kind of stimulation for treating intractable hypertension
With the electrode catheter of RF ablation renal sympathetic nerve.
Background technology
Clinically more typically, paathogenic factor is numerous, and pathogenesis is indefinite, and medication effect is very for intractable hypertension
Difference, diagnosis and treatment technology are still not mature enough, one of great difficult problem as hypertension therapeutic, and such patient is generally associated with
Other cardiovascular diseases, such as coronary heart disease, diabetes, heart failure, high fat of blood, ephrosis, peripheral arterial disease, apoplexy, left ventricle fertilizer
Thickness etc..It is the most notable with the infringement of the heart, brain, kidney in the various complication of hypertension, for example counted according to the World Health Organization,
50% angiocardiopathy is caused by hypertension.At present because pressure value increases, cardiocerebrovasculaevents events occur causes death
The annual whole world about 7,100,000 of number.And in more than the 40 years old cause of death of crowd of China, heart disease and cerebrovascular disease are classified as respectively
One and the 3rd, total the first dead hazards are hypertension.
Renal sympathetic nerve is played an important role in the generation and development of hypertension, and renin release is received by activating β 1
Body, sodium salt reabsorption is receptor-mediated by the α 1 of proximal tubule.The contraction that the acceptors of α 1 also take part in Renal vascular causes kidney blood
The reduction of stream.Angiotensin-Converting causes that angiotensinⅠ (abbreviation Ang I) is converted to angiotensinⅡ (abbreviation Ang
II), Ang II causes vessel retraction, and proximal tubular sodium salt reabsorption, aldosterone produces the activation with stomodaeal nervous system.Ang
The sympathetic nerve terminal of II pair of proximal tubular has facilitation so that norepinephrine release increases and increases with sodium salt reabsorption
By force.Sympathetectomy can prevent hypertension caused by Ang II, and this evidence supports the sympathetic nerve intervention inductions of Ang II
The viewpoint of hypertension.Ang II can cause swashing for renal sympathetic nerve by acting on rostral ventrolateral medulla nucleus neuron simultaneously
It is living.Ang II can further strengthen the propagation of vascular smooth muscle, cause the myocardial hypertrophy aldosterone to cause sodium water weight in distal tubule
Absorb.All these factor result in generation and the hair of hypertension eventually through cardiac output is increased with increase peripheral resistance
Exhibition.
As can be seen here, blood pressure is mainly adjusted by kidney.Nowadays the thinking of hypertension therapy is by medicine reduction
Angiotensins, however, the sympathetic nerve spread all on the arteria renalis is also to cause the arch-criminal of hypertension.If these nerves are excessively lived
Jump, secretion feritin is excessively too fast, is just enough to the effect that " counteracting " falls medicine step-down.
Arteria renalis inner membrance radio-frequency ablation procedure is that thoroughly effectively treatment intractable hypertension brings new hope, but at present also
There is no a kind of medicine equipment to be really used for clinical treatment intractable hypertension, finding report is also only limitted to the experimental stage.And
The conduit of prior art is simple, it is impossible to effectively and reliably treat intractable hypertension.
The content of the invention
The technical problem to be solved in the present invention is to provide a kind of same conduit of utilization rapidly and accurately on arteria renalis wall
The electrode catheter that sympathetic nerve is stimulated and melted.
In order to solve the above-mentioned technical problem, the technical solution adopted by the present invention is：
The arteria renalis of the invention stimulates ablating electrode conduit, is connected with turn from distal end to near-end and the electrode catheter may be guided
Insertion the arteria renalis and avoid electrode catheter termination damage arteria renalis inwall conductive filament head, can by change spatial form with adapt to
Arteria renalis inwall fully and be in close contact and renal sympathetic nerve therein is stimulated and ablative surgery basket, to basket rise
The pipe shaft of support effect, the control handle of control basket spatial form change and by the ring electrode on basket and external stimulation instrument
And radiofrequency generator is electrically connected and is fixed on the connector of the control handle afterbody, wherein, the length of the pipe shaft is in 70cm-
150cm。
The basket is made up of many strip arms and sizing core, and being fixed in proximally by near-end sizing core for strip arm is described
The distal end of pipe shaft, the distal end of strip arm is fixed in the near-end of the conductive filament head by distal end sizing core, what the strip arm was constituted
Spatial form can be changed into ellipsoid in the presence of along the axial force of the pipe shaft from the water chestnut cone post of original state, then become again
It is the fairing encirclement structure like space electronic track.
The strip arm is tubulose, and it is made by polyurethane, block polyamide or nylon, along it in the inner chamber of strip arm
NiTi flat filament axially is connected with, the NiTi flat filament can make correspondence strip brachiocylloosis under external force, after the external force is discharged,
Can restore correspondence strip arm.
The ring electrode is made by platinumiridio or gold, and at least 1 is distributed with the every outer surface of the strip arm
Individual ring electrode.
The ring electrode is arranged on the position of equal decile on strip arm.
The conductive filament head is linear helical spring, and its front end is the bead of semi-round ball；The helical spring is by straight
Footpath is close around forming around the center pivot made by other steel wires for the stainless steel wire of 0.05mm to 0.2mm, helical spring it is outer
In 0.4mm to 1.2mm, length is in 10mm to 35mm in footpath.
Be provided with temperature transducer on the inside of the ring electrode, temperature transducer by being placed through the pipe shaft, manipulation hand
The holding wire of handle is connected on the connector, and is connected with the temperature measurer in described radiofrequency generator by external cable.
The sizing core is for two and made by plastics or metal, and its section configuration is cellular, at the center of the section
Central circular hole is provided with, several rectangular openings are provided with around the central circular hole；Central circular hole and rectangular opening on distal end sizing core can
Think through hole or blind hole, the central circular hole and rectangular opening on near-end sizing core are through hole；Institute is stretched out at the two ends of the NiTi flat filament
Strip pipe be respectively and fixedly connected on the rectangular opening of correspondence position.
In the distal end, core of shaping can make the bracing wire steel wire of strip brachiocylloosis deformation to being provided between control handle, should
The distal end of bracing wire steel wire is fixed on the central circular hole on distal end sizing core, and the near-end of bracing wire steel wire is shaped on core through near-end
Central circular hole and inner cavity of tube body are connected on the handle inner core on control handle.
The maximum outside diameter of the spatial form that the basket is formed is in 2mm-18mm.
Electrode catheter of the invention can carry out electro photoluminescence to arteria renalis inner membrance, and mapping causes blood pressure significantly raised to because of stimulation
Point position, find sympathetic nerve close quarters, carry out positioning target spot ablation, it is significantly more efficient ablation arteria renalis wall on sympathetic god
Through.Basket is provided with the distal end of conduit, basket is made up of multiple space strip arms, proximally and distally connecting respectively for strip arm is led
Pipe pipe shaft and conductive filament head, the size of the spatial volume of basket are controlled by the control handle of catheter proximal end, so that strip arm overhead
Between the electrode and the arteria renalis inwall that are distributed fully, be in close contact, and one-time positioning Multi-contact just can complete to stimulate, melt,
The multiple surgical procedures for stimulating blood pressure to verify again, more accurate and effective removal renal sympathetic nerve.The present invention is capable of achieving dynamic for kidney
The stimulation mapping of arteries and veins, ablation, temperature control be on same ring electrode in completing, it is to avoid various process is changed caused by various apparatuses
Site error, more accurately, fast.
It can eliminate it is orthosympathetic be overexcited, easy during operation and safety, doctor under image-guided, by this hair
Bright electrode catheter carries out RF ablation to the sympathetic nerve spread all on arteria renalis tube wall, cuts away partial nerve, reduces sympathetic god
Through the function of conducts information, reduce renin secretion, so that angiotensins is reduced causes blood pressure reduction.
Brief description of the drawings
Schematic diagram when Fig. 1 is 8 original state of electrode catheter of the invention.
Schematic diagram when Fig. 2 is the spatial form of the basket 2 transformation ellipsoid 28 in Fig. 1.
Fig. 3 is A portions enlarged diagram (i.e. the enlarged drawing of basket 2) in Fig. 1.
Fig. 4 be Fig. 1 in the spatial form of basket 2 be transformed into similar spaces electron orbit fairing surround structure 29 amplification
Schematic diagram.
Fig. 5 is B-B section views enlarged diagram (i.e. the sectional view of pipe shaft 5) in Fig. 1.
Fig. 6 is the enlarged diagram of control handle 6 in Fig. 1.
Fig. 7 is the C-C section views enlarged diagram (sectional view of core of shaping) in Fig. 3.
Reference is as follows：
Conductive filament head 1, basket 2, distal end sizing core 21, near-end sizing core 22, strip arm 23, ring electrode 24, central circular hole 25,
Rectangular opening 26, water chestnut cone post 27, ellipsoid 28, fairing surround structure 29, bracing wire steel wire 3, electrified wire 4, pipe shaft 5, manipulation hand
Handle 6, connector 7, electrode catheter 8.
Specific embodiment
As shown in Figure 1, 2, the arteria renalis of the invention stimulates ablating electrode conduit to be applied to by the thorn to arteria renalis inwall
Swash and melt to treat hypertension, it is made up of conductive filament head 1, basket 2, pipe shaft 5, control handle 6 and connector 7.
1st, the conductive filament head 1 is arranged on the distalmost end of the electrode catheter 8 (with Fig. 1 papers direction as reference, left-hand is remote
End, dextrad is near-end), its effect is guiding catheter into the arteria renalis and avoids catheter end head from damaging arteria renalis inwall, its profile
It is linear helical Bourdon tube, the distal end of the helical Bourdon tube is the bead in semi-round ball being welded into using scolding tin.Spiral bullet
Spring be by the stainless steel wire of a diameter of 0.05mm to 0.2mm around the center pivot made by other steel wires close around forming, spiral
, in 0.4mm to 1.2mm, total length is in 10mm to 35mm for the external diameter of bourdon tube.
2nd, as shown in Figure 3,4, the basket 2 by many strip arms 23, shape core and be arranged on strip arm 23 ring electricity
Pole 24 is constituted, and the radical of the present invention preferably strip arm 23 is 4-8 roots.
1) every strip arm 23 is tubulose, and its external diameter is 0.4mm to 1.2mm, and internal diameter is 0.3mm to 1mm, and a length of 10mm is extremely
40mm, it is made by polyurethane, block polyamide or nylon, and approximate one of the original shape that all strip arms 23 are encircled into is by two
The water chestnut cone shape of post 27 that individual identical water chestnut cone is constituted in the way of bottom surface connects, every strip arm 23 is the one of water chestnut cone post 27
Bar incline.
Along its affixed resilient NiTi flat filament in axial direction in the inner chamber of strip arm 23, its thickness is 0.05mm to 0.2mm,
Width is 0.2mm to 0.8mm, preferred nickel/titanium alloy silk.
The NiTi flat filament can bend to the profile of different curvature under external force, and the bending can order about corresponding strip
Arm 23 bends, and after the external force is discharged, correspondence strip arm 23 can again restored.
2) the sizing core is made by plastics or metal material, and sizing core is two, is respectively distal end sizing core 21 and near
End locating core.Proximal end face center on distal end sizing core 21 is provided with central circular hole 25 and is put around the central circular hole 25
Multiple rectangular openings 26, central circular hole 25 and rectangular opening 26 can be through hole, or blind hole；On near-end sizing core 22
The size being provided with distal end sizing core 21 and central circular hole 25 and rectangular opening 26 as set location, but near-end sizing core
Central circular hole 25 and rectangular opening 26 on 22 are through hole (referring to Fig. 7).
The mouth of pipe that the strip arm 23 is stretched out in the distal end of the NiTi flat filament in every strip arm 23 is fixed in distal end sizing
On core 21 in the rectangular opening 26 of correspondence position, the mouth of pipe that the near-end of each NiTi flat filament stretches out the strip arm 23 is fixed in near-end and determines
On core 22 in the rectangular opening 26 of correspondence position.
Distal end sizing core 21 is fixed on the near-end of the conductive filament head 1, and near-end sizing core 22 is fixed on the remote of the pipe shaft 5
End.
In the distal end, core 21 of shaping can make the bracing wire steel of the strip arm 23 flexural deformation to being provided between control handle 6
Silk 3, the distal end of the bracing wire steel wire 3 is fixed on the central circular hole 25 on distal end sizing core 21, and the near-end of bracing wire steel wire 3 is through closely
Central circular hole 25 and the inner chamber of pipe shaft 5 on end sizing core 22 are connected on the handle inner core on control handle 6.
As shown in Figure 2,3, 4, when the bracing wire steel wire 3 is pulled to the direction of connector 7 along the axis of pipe shaft 5, the distal end
Sizing core 21 is pulled the spatial form for forcing the strip arm 23 to constitute to bore the shape of post 27 by the water chestnut of original state by the bracing wire steel wire 3
Shape gradually becomes ellipsoid 28, the i.e. spatial form of basket 2 and is changed into ellipsoid 28 from the water chestnut cone shape of post 27；Continue to draw and be somebody's turn to do
Bracing wire steel wire 3 then makes the basket 2 be changed into being surrounded like the fairing of space electronic track the shape of structure 29.When release is to bracing wire steel
During the external force of silk 3, under each strip arm 23 elastic restoring force effect of NiTi flat filament wherein on basket 2, it is set to surround composition
The spatial form of basket 2 be returned to original state water chestnut cone the shape of post 27.
3) at least one ring electrode 24 as shown in Figure 2,3, 4, is arranged with the outer surface of the every strip arm 23, the ring
Electrode 24 is made by platinumiridio or gold, and the external diameter of the ring electrode 24 being socketed on strip arm 23 is 0.4mm to 1.2mm, long
Spend for 0.5mm to 2mm.When the ring electrode 24 is for multiple, all ring electrodes 24 are uniformly arranged along the strip arm 23.
The distal end of each ring electrode 24 respectively electrified wire 4 of 0.1mm to 0.2mm a diameter of with is affixed, correspondence
Electrified wire 4 near-end through the central circular hole 25 on near-end sizing core 22 or the rectangular opening 26 of correspondence position, pipe shaft 5, behaviour
Control handle 6 connects with described connector 7, and is connected with stimulation instrument and radiofrequency generator by external wire.
Be provided with temperature transducer in the inner side of each ring electrode 24, temperature transducer by being placed through the pipe shaft 5, behaviour
The holding wire for controlling handle 6 is connected on the connector 7, and is connected with the temperature measurer in described radiofrequency generator by external cable
Connect.The temperature transducer is Medical temperature measuring sensor, or conventional thermistor or thermocouple.
The change of the spatial form of basket 2 can make it into the arteria renalis after with the fully and tight patch with arteria renalis inwall
Touch.The maximum outside diameter of the spatial form that the basket 2 is formed is in 2mm-18mm.
When basket 2 is into the arteria renalis and after being closely affixed with arteria renalis inwall, connecting ring electrode 24 and stimulation instrument or penetrate
The electrical connection of frequency instrument, you can electro photoluminescence or RF ablation are carried out to the sympathetic nerve on arteria renalis tube wall.
3rd, the pipe shaft 5 is made by polyurethane, block polyamide or nylon material, its length in 70cm-150cm, in it
Chamber is hollow channel, for placing described bracing wire steel wire 3, electrified wire 4 and holding wire (referring to Fig. 5).
Stainless steel cloth is equipped with the inwall of pipe shaft 5, its effect is the intensity and pliability for strengthening the pipe shaft 5.
4th, as shown in fig. 6, being provided with handle inner core in the control handle 6, the handle inner core and the inner chamber of control handle 6 it
Between using threaded connection, control handle is provided with outside control crank, by turn control handle adjustable handle inner core along grasp
The axis direction for controlling handle 6 is moved back and forth.
The near-end of described bracing wire steel wire 3 is fixed in the distal end of the handle inner core, when forward or backwards rotating described control
During knob processed, you can make the traction or release of 3 pairs of baskets 2 of bracing wire steel wire.
5th, the connector 7 is arranged at the afterbody of control handle 6, and it passes through external cable with described stimulation instrument and radio frequency
Instrument is connected.
Claims (10)
1. a kind of arteria renalis stimulates ablating electrode conduit, it is characterised in that：It is connected with turn from distal end to near-end and the electricity may be guided
The pole conduit insertion arteria renalis and avoid electrode catheter termination damage arteria renalis inwall conductive filament head (1), can be by changing space shape
Shape with adapt to arteria renalis inwall fully and be in close contact and renal sympathetic nerve therein stimulated and ablative surgery net
Basket (2), the pipe shaft (5) that support is played to basket (2), the control handle (6) of control basket (2) spatial form change and by net
Ring electrode (24) on basket (2) is electrically connected with external stimulation instrument and radiofrequency generator and is fixed on the control handle (6) afterbody
Connector (7), wherein, the length of the pipe shaft (5) is in 70cm-150cm.
2. the arteria renalis according to claim 1 stimulates ablating electrode conduit, it is characterised in that：The basket (2) is by many
Strip arm (23) and sizing core constitute, strip arm (23) proximally by near-end shape core (22) be fixed in the pipe shaft (5)
Distal end, the distal end of strip arm (23) is fixed in the near-end of the conductive filament head (1), the strip arm by distal end sizing core (21)
(23) spatial form for constituting can bore post (27) and become in the presence of along the axial force of the pipe shaft (5) by the water chestnut of original state
It is ellipsoid (28) to be then changed into surrounding structure (29) like the fairing of space electronic track again.
3. the arteria renalis according to claim 2 stimulates ablating electrode conduit, it is characterised in that：The strip arm (23) is pipe
Shape, it is made by polyurethane, block polyamide or nylon, and it is flat along its axial direction to be connected with NiTi in the inner chamber of strip arm (23)
Silk, the NiTi flat filament can bend under external force correspondence strip arm (23), after the external force is discharged, can make correspondence strip
Arm (23) is restored.
4. the arteria renalis according to claim 1 stimulates ablating electrode conduit, it is characterised in that：The ring electrode (24) is by platinum
Iridium alloy or gold are made, and at least one ring electrode (24) is distributed with the every outer surface of the strip arm (23).
5. the arteria renalis according to claim 4 stimulates ablating electrode conduit, it is characterised in that：The ring electrode (24) is set
The position of equal decile on strip arm (23).
6. the arteria renalis according to claim 1 stimulates ablating electrode conduit, it is characterised in that：The conductive filament head (1) is straight
The helical spring of line style, its front end is the bead of semi-round ball；The helical spring is by the stainless of a diameter of 0.05mm to 0.2mm
Steel wire encircling is close around forming by the center pivot that other steel wires make, and in 0.4mm to 1.2mm, length exists the external diameter of helical spring
10mm to 35mm.
7. the arteria renalis according to claim 1 stimulates ablating electrode conduit, it is characterised in that：In the ring electrode (24)
Side is provided with temperature transducer, temperature transducer by being placed through the pipe shaft (5), the holding wire of control handle (6) is connected to
On the connector (7), and it is connected with the temperature measurer in described radiofrequency generator by external cable.
8. the arteria renalis according to claim 3 stimulates ablating electrode conduit, it is characterised in that：It is described sizing core be two simultaneously
Made by plastics or metal, its section configuration is cellular, and central circular hole (25) is provided with the center of the section, around the center
Circular hole (25) is provided with several rectangular openings (26)；Central circular hole (25) and rectangular opening (26) on distal end sizing core (21) can be
Through hole or blind hole, the central circular hole (25) and rectangular opening (26) that near-end is shaped on core (22) are through hole；The two of the NiTi flat filament
Strip pipe where end is stretched out is respectively and fixedly connected on the rectangular opening of correspondence position (26).
9. the arteria renalis according to claim 8 stimulates ablating electrode conduit, it is characterised in that：In distal end sizing core
(21) the bracing wire steel wire (3) of the strip arm (23) flexural deformation, the bracing wire steel wire can be made to being provided between control handle (6)
(3) distal end is fixed on the central circular hole (25) that distal end is shaped on core (21), and the near-end of bracing wire steel wire (3) is shaped through near-end
Central circular hole (25) and pipe shaft (5) inner chamber on core (22) are connected on the handle inner core on control handle (6).
10. the arteria renalis according to claim 1 stimulates ablating electrode conduit, it is characterised in that：What the basket (2) was formed
The maximum outside diameter of spatial form is in 2mm-18mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710176340.3A CN106901831A (en) | 2017-03-23 | 2017-03-23 | The arteria renalis stimulates ablating electrode conduit |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710176340.3A CN106901831A (en) | 2017-03-23 | 2017-03-23 | The arteria renalis stimulates ablating electrode conduit |
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| CN106901831A true CN106901831A (en) | 2017-06-30 |
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| CN201710176340.3A Pending CN106901831A (en) | 2017-03-23 | 2017-03-23 | The arteria renalis stimulates ablating electrode conduit |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111227929A (en) * | 2018-11-29 | 2020-06-05 | 上海安臻医疗科技有限公司 | Adjustable bronchus thermoforming pipe |
| WO2020232850A1 (en) * | 2019-05-17 | 2020-11-26 | 杭州睿笛生物科技有限公司 | Electrical pulse-related parallel electrodes |
| CN113018645A (en) * | 2019-12-07 | 2021-06-25 | 贵州医科大学 | Blood vessel wall injection catheter system based on electrified expansion medicine bag |
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