CN202637109U - Multiple-electrode hypertension endovascular radiofrequency ablation treatment catheter - Google Patents
Multiple-electrode hypertension endovascular radiofrequency ablation treatment catheter Download PDFInfo
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- CN202637109U CN202637109U CN 201220267954 CN201220267954U CN202637109U CN 202637109 U CN202637109 U CN 202637109U CN 201220267954 CN201220267954 CN 201220267954 CN 201220267954 U CN201220267954 U CN 201220267954U CN 202637109 U CN202637109 U CN 202637109U
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Abstract
The utility model discloses a multiple-electrode hypertension endovascular radiofrequency ablation treatment catheter which comprises a connector, a handle, a catheter body and a plurality of electrodes, wherein one end of the catheter body is connected with the connector, the other end of the catheter body is provided with the plurality of electrodes, one end of the catheter body is close to the connector and is provided with the handle, and the electrodes are distributed along a linear vertical axis in divergent angle mode. A catheter main body is a pipe body formed by warm plastic polymer and wire meshes in a composite mode, and the near end of the catheter main body is big in rigidity, and the remote end of the catheter main body is soft. The front end of the catheter body is provided with a remote end electrode made of platinum composite materials, and a plurality of guide lines of the electrodes are connected with the connector through a channel in the catheter body. The multiple-electrode hypertension endovascular radiofrequency ablation treatment catheter has the functions of monitoring of temperature of renal artery vascular tissues and determination of renal artery organization local impedance, is used for feedback and regulation of current intensity of radiofrequency, blocks bilateral kidney sympathetic nerves, blocks up the sympathetic nerves and stimulates the kidneys to secrete rennin-angiotensin, and achieves purposes of fall of blood pressure and cure of hypertension.
Description
Technical field
This utility model relates to a kind of hypertensive conduit of clinical treatment that is applied to, particularly radiofrequency ablation therapy conduit in a kind of multipole hypertension blood vessel.
Background technology
Hypertension is to have a strong impact on people's life quality and life-threatening common disease, also is that the whole world causes dead Etiological, and the annual whole world 7 million peoples are dead because of hypertension.Point out in " Chinese residents nutrition and the investigation of health conditions report " of issuing in information office of State Council on the 12nd news briefing October in 2004: China's adult hypertension prevalence is 18.8%, and crowd's hypertension awareness, treatment rate and control rate only are 30.2%, 24.7% and 6.1%.Even in the U.S., the control rate of hypertension treatment in recent years is less than 30% also.Yet treatment, the recent year Epidemiological study shows, men and women's prevalence all surpasses more than 20%, China is one of the most serious country of in the world hypertension harm at present, estimate that national hyperpietic surpasses 200,000,000, in the international coverage, the whole world has 1,000,000,000 people to suffer from hypertension at present, expecting hyperpietic in 2025 will have 30% people to suffer from hypertension, sum reach 1,500,000,000 (.This shows that hypertension has become that global range comprises that the present prevalence of China is the highest, one of the ill the most general disease of crowd, the research of hypertensive research and new treatment becomes human instant problem.
The serious consequence that hyperpietic's blood pressure increases is the infringement to the whole body vitals.Because the arterial pressure persistence raises, cause the whole body arteriolosclerosis, thereby the blood supply that affects histoorgan is not enough, Endovascular pressure raises, cause the most serious complication of infringement of heart and brain, kidney, and easily cause coronary heart disease, brain apoplexy, renal failure, and the disability rate that causes and mortality rate obviously increase:
Popular hypertension therapeutic remains Drug therapy both at home and abroad at present.The purpose of its treatment be by drug effect in the links that causes hypertension, disturb the effect cause hypertension in the body and control blood pressure; Mainly be to rely on medicine on the Therapeutic Method, wherein of greatest concern and what play a major role is calcium channel blocker, angiotensin-convertion enzyme inhibitor and angiotensin ii receptor antagonist, and two class medicines are main after outstanding, and the effect of these rear two class medicines is all in renin-angiotensin system.The treatment of the Long term combined medication of such medicine, will not only need long-term taking and expensive, side effect outstanding, most importantly therapeutic effect is still undesirable.Data shows that the present hypertensive treatment rate of China and control rate only are 24.7% and 6.1%.Therefore, the condition of medicine treatment for hypertension that generally believes global range still, individual variation more because of side effect, control rate is still not good, because the mortality rate that hypertension causes can be in any more.
The basic cause of essential hypertension is brought out owing to the sympathetic nerve overacfivity and is kept.Radiolabel shows that the hyperpietic exists the too much noradrenaline secretion of kidney and enters blood system.Thereby interior all blood vessel, renal tubules and the juxtaglomerular apparatuses of domination kidney were regulated renin angiotensin aldosterone system after nerve entered kidney behind the sympathetic ganglion of domination kidney, conversely, vasotonia speed II can increase again adrenal gland's energy neurotransmission of central mechanism and acceleration SNE.So, orthosympathetic effect causes blood pressure to increase.Thereby generally believe that at present the orthosympathetic activity of kidney is the major reason that causes essential hypertension.
External zoopery and clinical experiment confirm: blocking-up kidney sympathetic nerve, can not cause that not only the kidney normal function lowers, and systolic pressure and diastole are all descended, this explanation, although essential hypertension has multifactor existence, the orthosympathetic activity of domination kidney and tension force are to play an important role in hypertension existence and the progress.The surgery wide excision visceral nerve operation of previously once carrying out can reduce renin secretion, do not reduce the filtration rate of kidney blood flow and glomerule, still can keep electrolytical balance.But so widely visceral nerve blocking-up operation has caused the complication of very high peri-operation period, and because of the sickness rate of lacking of proper care of other viscera functions after visceral nerve is removed widely also very high.The kidney transfer operation of at present clinical more enforcement then can illustrate well, remove the kidney nerve after, kidney still can keep the stable of power and water solution matter.Also observe in zoopery, when hypertension, the sympathetic nervous system of kidney and body is closely related.Therefore, if optionally in one organ level blocking-up renin-angiotensin system, then can interrupt the hypertensive effect of liter of renin-angiotensin system, simultaneously, because the reduction of renin-angiotensin system vaso-active substance, it is also weakened the orthosympathetic activation effect of whole body, thereby keeping under the complete prerequisite of renal function systemic blood pressure being descended, reaches the hypertensive purpose for the treatment of.Be that super-selective blocking-up kidney sympathetic nerve will make blood pressure drops, can avoid other on the unnecessary impact of bodily tissue and organ simultaneously.
The utility model content
In order to solve the problems of the technologies described above, this utility model provides radiofrequency ablation therapy conduit in a kind of multipole hypertension blood vessel.The method that the Wicresoft that this utility model adopts gets involved, percutaneous puncture intravascular intracavity arrives renal artery, the bilateral renal arteries tube wall is imposed the high frequency current in short bursts, sympathetic nerve on the renal artery wall is destroyed, sympathetic nerve interrupts for the domination of kidney, feritin-angiotensin is reduced for a long time, thereby blood pressure drops reach the hypertensive effect for the treatment of.
The technical scheme that this utility model solves the problems of the technologies described above is: comprise joint, handle, catheter tube, a plurality of electrode; One end of described catheter tube links to each other with joint, and the other end is provided with a plurality of electrodes, and the end that catheter tube is abutted against head is provided with handle.
In the interior radiofrequency ablation therapy conduit of above-mentioned multipole hypertension blood vessel, described catheter tube comprises conduit cavity, conduit internal layer, tinsel reinforcement net, catheter outer, tinsel is strengthened net and is tightly held the conduit internal layer, and catheter outer and tinsel are strengthened the net fusion and covered outside it.
In the radiofrequency ablation therapy conduit, described electrode distributes by 360 degree minute angles and along the straight line longitudinal axis in the above-mentioned multipole hypertension blood vessel.
In the radiofrequency ablation therapy conduit, described electrode adopts platinum composite or other conducting metal to make in the above-mentioned multipole hypertension blood vessel, and an end of NiTi position line links to each other with electrode, and the other end of NiTi position line links to each other with joint through conduit cavity.
In the radiofrequency ablation therapy conduit, be provided with thermocouple in the described electricity in the above-mentioned multipole hypertension blood vessel, the wire of thermocouple output in conduit cavity received joint.
In the radiofrequency ablation therapy conduit, be provided with the wire that transmits radiofrequency signal and impedance measuring in the described conduit cavity in the above-mentioned multipole hypertension blood vessel, one of the wire of biography transmission radiofrequency signal and impedance measuring terminates to joint, and the other end is received the solder joint in the electrode.
Ultimum Ti with memory performance is housed in each electrode to distribute and can attach suitably the renal artery inwall when this conduit self-aiming conduit release to guarantee that angle is correct.
Technique effect of the present utility model is: 1) this utility model is equipped with the NiTi position line with memory performance in each electrode, can guarantee so the correct distribution of angle and can attach suitably the renal artery inwall when this conduit self-aiming conduit is released.2) this utility model catheter tube be divided into harder proximal segment and softer distal ports, be convenient to like this conduit propelling movement in vivo.2) proximal segment adopts the polymer of high rigidity, and handle is convenient to propelling movement, tractive or rotation, with regulate that conduit moves in blood vessel and towards.The efficient electric isolated tube of 3) packing in this utility model body passage guarantees the transmission of the signal of telecommunication, and multipole design both had been convenient to the calibration of ablation site and disposable a side kidney sympathetic nerve had been melted, and can reduce or avoid melting again the complication of rear renal artery stenosis.
Description of drawings
Fig. 1 is the structure chart of four electrode hypertension blood vessel internal treatment radio-frequency (RF) therapy conduits in this utility model.
Fig. 2 is the structure chart of six electrode hypertension blood vessel internal treatment radio-frequency (RF) therapy conduits in this utility model.
Fig. 3 is the cutaway view of catheter tube in this utility model.
Fig. 4 is the cut-away view of termination electrode and connection tube thereof in this utility model.
The specific embodiment
Referring to Fig. 1 and Fig. 2 figure.This utility model is followed successively by jointing 1, handle 2, catheter tube 3, electrode 4 from near-end to far-end.The electrode of Fig. 1 is four, and the electrode among Fig. 2 is six, and electrode is to distribute by 360 degree minute angles and along the straight line longitudinal axis.Multipole when being quadrupole, this calibration is that pole spacing is 90 degree; When being five utmost points, this calibration is that pole spacing is 72 degree when multipole; When being six types of severe debility disease, this calibration is that pole spacing is 60 degree when multipole.Electrode is signal of telecommunication output and collecting part, and the body rear portion is joint and the joystick of signal of telecommunication input and output.
Referring to Fig. 3, Fig. 3 is the cutaway view of catheter tube.Catheter tube 3 comprises conduit cavity 8, conduit internal layer 7, tinsel reinforcement net 9, catheter outer 6, and tinsel is strengthened net and tightly held the conduit internal layer, and catheter outer and tinsel are strengthened the net fusion and also covered outside it.Described catheter tube 3 is divided near the proximal segment of handle with near the distal ports of electrode, and proximal segment adopts the polymer of high rigidity, and distal ports adopts the low polymeric material of hardness number, and heat fuses and connects two sections and get final product.Electric isolated tube 5 by temperature-sensitive signal, impedance signal wire and radio-frequency current output is arranged in the conduit cavity interior 8.
Fig. 4 is distal end of catheter of the present utility model and electrode interior structure chart.As seen the wire 10 from thermocouple 11 that passes through in the electric isolated tube passes the wire 14 and NiTi position line 13 and the solder joint 15 that transmit radiofrequency signal and impedance measuring.
Each electrode differently branches out single electrode according to what tell position and angle from the conduit main shaft.Termination electrode 12 is made by platinum, platinumiridio, silver or other metals with excellent conductive performance, and wire 10, radio frequency output and impedance measuring wire 14 can adopt the wire producing with insulating properties.One end of radio frequency output and impedance measuring wire 14 is welded on the solder joint 15 of termination electrode 12, and an end of wire 10 is connected on the thermocouple 11 of temperature measuring, then by the electric isolated tube 5 in the body, is welded at last on the joint 1.One end of NiTi position line 13 links to each other with the termination electrode 12 of electrode 4, and the other end of NiTi position line 13 links to each other with joint 1 through conduit cavity 8.
NiTi position line with memory performance is housed in each electrode in this utility model can be guaranteed the correct distribution of angle and can attach suitably the renal artery inwall when this conduit self-aiming conduit is released.
Electrode is except by the angular distribution in this utility model, and for avoiding at the renal artery stenosis of blood vessel because causing in the same plane radio-frequency (RF) ablation, each electrode can be spaced apart in 10-20 mm length scope of overall length on the renal artery longitudinal axis.As seen, because 360 minutes angles of electrode distribute and distribute along the renal artery longitudinal axis, after electrode self-aiming conduit was released, each electrode was rendered as the multipole distribution of bung flange shape.Handle is convenient to propelling movement, tractive or rotation, with regulate that conduit moves in blood vessel and towards.
Experiment in the animal body of the present utility model: after femoral arteriography has been put hemostatic catheter, send into guiding catheter through this hemostatic catheter, x-ray DSA observes the lower front end of guiding catheter that confirms and arrives in the renal artery, then, hypertension blood vessel internal treatment catheter is sent into through guiding catheter.Under x-ray DSA observes, when conduit is sent guiding catheter, each electrode will automatically spring open and be attached to the renal artery inwall.Notice that each termination electrode arrives the renal artery proper site and the distribution length on the renal artery longitudinal axis is suitable.Jointing is measured the impedance of renal artery inwall to radiofrequency generator, and adjusting and setting impedance is that 100 Europe are female, and temperature control is set in the 55-60 degree, and the radio frequency export-restriction then be multiply by electrodeplate by each electrode power 5-8 watt; When quadrupole, 5-8 watt X4=20-32 watt; During six types of severe debility disease, 5-8 watt X6=30-48 watt; So analogize, the radio frequency output time is set as 60-120 second.Renal artery is implemented to melt.One side is finished the endarterial same operation of contralateral kidney after finishing then.After finished both sides, radiofrequency catheter withdrawed from, and withdrawed from externally via guide wire, and local point of puncture hemostasis wrapping finishes operation.Guiding catheter is withdrawed from the hypertension blood vessel internal treatment catheter collection, withdraw from hemostatic catheter, point of puncture compressing blood.
Claims (10)
1. the interior radiofrequency ablation therapy conduit of multipole hypertension blood vessel is characterized in that: comprise joint (1), handle (2), catheter tube (3), a plurality of electrode (4); One end of described catheter tube (3) links to each other with joint, and the other end is provided with a plurality of electrodes (4), and the end that catheter tube (3) is abutted against head (1) is provided with handle (2).
2. radiofrequency ablation therapy conduit in the multipole hypertension blood vessel according to claim 1, it is characterized in that: described catheter tube (3) comprises conduit cavity (8), conduit internal layer (7), tinsel reinforcement net (9), catheter outer (6), tinsel is strengthened net (9) and is tightly held conduit internal layer (7), and catheter outer (6) merges with tinsel reinforcement net (9) and covers outside it.
3. radiofrequency ablation therapy conduit in the multipole hypertension blood vessel according to claim 1, it is characterized in that: described electrode distributes by 360 degree minute angles and along the straight line longitudinal axis.
4. radiofrequency ablation therapy conduit in the multipole hypertension blood vessel according to claim 1, it is characterized in that: described electrode (4) adopts platinum composite or other conducting metal to make, one end of NiTi position line (13) links to each other with electrode (4), and the other end of NiTi position line (13) links to each other with joint (1) through conduit cavity (8).
5. radiofrequency ablation therapy conduit in the multipole hypertension blood vessel according to claim 1, it is characterized in that: be provided with thermocouple (11) in the described electrode (4), the wire (10) of thermocouple (11) output in conduit cavity (8) received joint (1).
6. radiofrequency ablation therapy conduit in the multipole hypertension blood vessel according to claim 1, it is characterized in that: be provided with the wire (14) that transmits radiofrequency signal and impedance measuring in the described conduit cavity (8), one of the wire (14) of transmission radiofrequency signal and impedance measuring terminates to joint (1), and the other end is received the solder joint (15) in the electrode (4).
7. radiofrequency ablation therapy conduit in the multipole hypertension blood vessel according to claim 1, it is characterized in that: when described electrode was 4, the angle between the electrode was 90 degree.
8. radiofrequency ablation therapy conduit in the multipole hypertension blood vessel according to claim 1, it is characterized in that: when described electrode was 6, the angle between the electrode was 60 degree.
9. radiofrequency ablation therapy conduit in the multipole hypertension blood vessel according to claim 1, it is characterized in that: described catheter tube (3) is divided near the proximal segment of handle with near the distal ports of electrode, proximal segment adopts the polymer of high rigidity, distal ports adopts the low polymeric material of hardness number, and heat fuses two sections of connections and gets final product.
10. radiofrequency ablation therapy conduit in the multipole hypertension blood vessel according to claim 1, it is characterized in that: be provided with electric isolated tube (5) in the described catheter tube (3), the wire (10) that links to each other with electrode (4) all passes electric isolated tube (5) with the wire (14) that transmits radiofrequency signal and impedance measuring and links to each other with joint (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220267954 CN202637109U (en) | 2012-06-08 | 2012-06-08 | Multiple-electrode hypertension endovascular radiofrequency ablation treatment catheter |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220267954 CN202637109U (en) | 2012-06-08 | 2012-06-08 | Multiple-electrode hypertension endovascular radiofrequency ablation treatment catheter |
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| Publication Number | Publication Date |
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| CN202637109U true CN202637109U (en) | 2013-01-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 201220267954 Expired - Fee Related CN202637109U (en) | 2012-06-08 | 2012-06-08 | Multiple-electrode hypertension endovascular radiofrequency ablation treatment catheter |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102697555A (en) * | 2012-06-08 | 2012-10-03 | 湖南依微迪医疗器械有限公司 | Multi-electrode hypertension endovascular radio-frequency ablation catheter |
| CN104546117A (en) * | 2013-10-25 | 2015-04-29 | 柯惠有限合伙公司 | Electrode ablation balloon catheter |
| CN105748146A (en) * | 2016-02-01 | 2016-07-13 | 华南理工大学 | Multichannel heat-conducting-fiber-targeting hot knife treatment equipment |
| CN105997236A (en) * | 2016-05-06 | 2016-10-12 | 上海安臻医疗科技有限公司 | A bronchial thermoplasty catheter |
| US9597147B2 (en) | 1999-11-16 | 2017-03-21 | Covidien Lp | Methods and systems for treatment of tissue in a body lumen |
| US10278774B2 (en) | 2011-03-18 | 2019-05-07 | Covidien Lp | Selectively expandable operative element support structure and methods of use |
| CN111920395A (en) * | 2020-07-22 | 2020-11-13 | 上海掌门科技有限公司 | Pulse acquisition device |
-
2012
- 2012-06-08 CN CN 201220267954 patent/CN202637109U/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9597147B2 (en) | 1999-11-16 | 2017-03-21 | Covidien Lp | Methods and systems for treatment of tissue in a body lumen |
| US10278774B2 (en) | 2011-03-18 | 2019-05-07 | Covidien Lp | Selectively expandable operative element support structure and methods of use |
| CN102697555A (en) * | 2012-06-08 | 2012-10-03 | 湖南依微迪医疗器械有限公司 | Multi-electrode hypertension endovascular radio-frequency ablation catheter |
| CN104546117A (en) * | 2013-10-25 | 2015-04-29 | 柯惠有限合伙公司 | Electrode ablation balloon catheter |
| CN105748146A (en) * | 2016-02-01 | 2016-07-13 | 华南理工大学 | Multichannel heat-conducting-fiber-targeting hot knife treatment equipment |
| CN105997236A (en) * | 2016-05-06 | 2016-10-12 | 上海安臻医疗科技有限公司 | A bronchial thermoplasty catheter |
| CN111920395A (en) * | 2020-07-22 | 2020-11-13 | 上海掌门科技有限公司 | Pulse acquisition device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130102 Termination date: 20180608 |