CN203350171U - Terahertz system sample sampling device for stomach cancer test - Google Patents
Terahertz system sample sampling device for stomach cancer test Download PDFInfo
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- CN203350171U CN203350171U CN 201320296107 CN201320296107U CN203350171U CN 203350171 U CN203350171 U CN 203350171U CN 201320296107 CN201320296107 CN 201320296107 CN 201320296107 U CN201320296107 U CN 201320296107U CN 203350171 U CN203350171 U CN 203350171U
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Abstract
The utility model discloses a Terahertz system sample sampling device for a stomach cancer test. The Terahertz system sample sampling device comprises a device structure and a collection light path. In the device structure, a motor is mounted a top plate, and a base is mounted at the lower part of left and right side plates; linear optical axes are mounted at four right-angled ends of the base; vertical and horizontal translation mechanisms are mounted on a lifting table respectively; a sample rack is mounted on the horizontal translation mechanism; a motor controller is arranged at the right end of the base plate; two left linear optical axis bearings and two right linear optical axis bearings are mounted at the left end and the right end of the lifting table respectively; one end of a left screw rod and one end of a right screw rod are fixed at the left end and the right end of the lower end of the top plate, while the other ends are fixed on the base plate after passing through through-holes on the lifting table; a femtosecond laser pulse in the collection light path pass through a half-wave plate, and is divided into a pumping pulse and a probe pulse by a beamsplitter; and the pumping pulse passes through an optical delay line and goes into a base surface of an antenna emitting electrode. The Terahertz system sample sampling device has the advantages of quick and compact sample installation, high measuring accuracy, and accurate data acquisition.
Description
Technical field
The utility model relates to a kind of Terahertz system sample sampling apparatus, relates in particular to a kind of for cancer of the stomach detection Terahertz system sample sampling apparatus.
Background technology
China is the district occurred frequently of cancer of the stomach, and year newly-increased patient is people more than 400,000 approximately, accounts for 42% of whole world number of the infected, and the incidence of disease is and increases year by year trend.THz wave (Terahertz Wave, abbreviation THz ripple) be often referred to the electromagnetic radiation of frequency in 0.1～10THz scope, the THz spectrum of material mainly depends on the space structure of molecule and the interaction between molecule, corresponding vibration mode has comprised in molecule and intermolecular vibration (collective vibration), for the biological macromolecular structure of research, intermolecular reaction, molecule and environment interphase interaction etc., has unique advantage.External existing researchist diagnoses the THz ripple for infantile tumour at present, and has obtained gratifying achievement.In Terahertz systematic sampling process, sample making is a very important link in the Terahertz experimentation, and the quality of its making directly affects the Exact Travelling of data.But due to the polytrope of sample and the complicacy of test process, make complex operation in the process of changing sample and experiment, conventional efficient is low, and system is unstable.Developing clamped one time, to complete multi-point sampler, faster specimen holder easily be to improve the effective way that cancer of the stomach detects the Terahertz system effectiveness.
Summary of the invention
The purpose of this utility model is for problems of the prior art, provides a kind of and detects Terahertz system sample sampling apparatus for cancer of the stomach.
A kind of for cancer of the stomach detection Terahertz system sample sampling apparatus, comprise apparatus structure and gather light path.In apparatus structure, the left side of left stepper motor and right stepper motor, top board has been installed on top board left plate has been installed, right plate has been installed on the right side of top board; Base has been installed in the bottom of left plate and right plate; Approach switch has been installed in the middle and lower part of left plate, and four right angle ends of base have been installed the straight line optical axis, i.e. two left straight line optical axises and two right straight line optical axises; Longitudinal translation mechanism and laterial translation mechanism have been installed respectively on lifting table, specimen holder has been installed on laterial translation mechanism, the right-hand member of base plate is provided with electric machine controller, two left straight line optical axis bearings and two right straight line optical axis bearings have been installed respectively in the two ends, left and right of lifting table, one end of left straight line optical axis, right straight line optical axis is separately fixed at left end and the right-hand member of top board lower surface, the other end is fixed on base after passing the left straight line optical axis bearing and right straight line optical axis bearing on lifting table; The end of left screw mandrel, right screw mandrel is separately fixed at left end and the right-hand member of top board lower surface, and the other end is fixed on base through the through hole on lifting table; And left screw mandrel, left straight line optical axis, right screw mandrel, right straight line optical axis and left plate, right plate are parallel;
Longitudinal translation mechanism comprises lifting table, left rail cushion block, left line slideway, left linear slider, vertical platform, vertical stepper motor, right guide rail cushion block, right line slideway, right straight-line guide rail slide block; The lifting table upper surface is equipped with on the left rail cushion block and right guide rail cushion block; Left line slideway is housed on the left rail cushion block, and left line slideway is provided with left linear slider, and left linear slider is arranged on vertical platform lower surface; Right guide rail cushion block is provided with right line slideway, and right line slideway is provided with right linear slider, and right linear slider is arranged on vertical platform lower surface.The lifting table upper surface is provided with vertical motor contiguous block, vertically on the motor contiguous block, vertical stepper motor is housed, vertically the front end of stepper motor is equipped with vertical shaft coupling, vertically shaft coupling is connected with an end of vertical screw mandrel by end bearing before vertical screw mandrel, vertically on the other end of screw mandrel, be provided with vertical screw mandrel bolt, vertically the screw mandrel bolt is connected with vertical platform with vertical platform contiguous block II by vertical platform contiguous block I.
In described longitudinal sliding motion mechanism, lifting table is connected with the left rail cushion block by vertical coupling bolt, and the left rail cushion block passes through the guide rail coupling bolt and is connected with left line slideway.Left linear slider is housed on left line slideway, and left linear slider is connected with vertical platform by the slide block coupling bolt.
Laterial translation mechanism comprise cross lead screw terminal shaft bearing, laterally the bearing terminal shaft hold, end bearing before end bearing block, cross lead screw before cross lead screw, horizontal platform, horizontal platform contiguous block, cross lead screw bolt, cross lead screw, laterally shaft coupling, cross motor contiguous block, cross motor, cross motor contiguous block bolt, rear rail cushion block, transverse slider, fromer rail cushion block;
Vertically on platform, be fixedly installed cross lead screw terminal shaft bearing, the front end bearing block of cross lead screw and cross motor contiguous block, cross lead screw terminal shaft bearing is provided with horizontal bearing terminal shaft and holds, laterally the bearing terminal shaft holds with an end of cross lead screw and fixes, after the other end of cross lead screw passes the front end bearing of cross lead screw of installing on the front end bearing block of cross lead screw, with an end of horizontal shaft coupling, be connected, laterally the other end of shaft coupling is connected with the output shaft of cross motor; Cross motor is fixedly installed on the cross motor contiguous block, and the cross motor contiguous block is connected with vertical platform by cross motor contiguous block bolt.Vertically rear portion and the front portion of platform are respectively equipped with rear rail cushion block and fromer rail cushion block, and the rear rail cushion block is connected with horizontal platform by transverse slider with the fromer rail cushion block.
Specimen holder comprises specimen holder lid, sample bin, sample bin air intake opening, sample bin support, sample bin support bracket bolt, specimen holder base plate; On the specimen holder base plate, by the sample bin support bracket bolt, with sample bin support lower end, be connected, sample bin support upper end is provided with sample bin, the lower surface of sample bin has the sample bin air intake opening, upper surface is provided with the specimen holder lid, be provided with sample panel, cladding plate in sample bin, cladding plate is arranged on the front portion of sample panel, and a side of sample bin is provided with humidity sensor.
Be provided with sample panel, cladding plate in sample bin, and cladding plate is connected with sample panel by the cladding plate bolt, sample panel is positioned at specimen holder lid bottom, its front portion is provided with sample, the front portion of sample is provided with cladding plate, cladding plate is pressed on sample by the cladding plate spring, and the right side of cladding plate spring is provided with the cladding plate setting nut, and cladding plate setting nut and cladding plate spring all are contained on the cladding plate bolt.
Described collection light path comprises electric machine controller, femto-second laser, the collimation lens I, half slide, beam splitter, the collimation lens II, the catoptron I, the differential detector I, the differential detector II, wollaston prism, quarter-wave plate, the ZnTe crystal, Si mirror, the paraboloidal mirror I, the paraboloidal mirror II, the sample sampling apparatus, the paraboloidal mirror III, the paraboloidal mirror IV, the GaAs crystal, the catoptron II, the catoptron III, the catoptron IV, chopper, lock-in amplifier, computing machine, electric machine controller, electric platforms,
The laser that femto-second laser produces is divided into two-way by beam splitter after by collimation lens I and half slide, first via laser arrives the catoptron IV by chopper incide the catoptron I after the collimation lens II after, laser arrives the paraboloidal mirror III by the GaAs crystal after catoptron IV, catoptron II, catoptron III, arrive the paraboloidal mirror II after passing sample and sample sampling apparatus afterwards after the refraction of paraboloidal mirror IV, laser is through paraboloidal mirror II, paraboloidal mirror I, Si mirror, ZnTe crystal; The second road laser arrives the ZnTe crystal after reflecting through Si mirror and first via laser converges.Laser after converging arrives computing machine through quarter-wave plate, wollaston prism, differential detector I, differential detector II, lock-in amplifier, nitrogen cylinder is connected in the sample sampling apparatus by tracheae, and whole process is completed by the motor controller controls electric platforms.
The utility model beneficial effect is as follows:
1, the utility model adopts vertical structure, elegant in appearance, convenient operating maintenance.Adopt industrial computer to realize the Automatic Control of test process, pass through residing position, function software Quality control storehouse.
2, sample is easy for installation, according to the diameter of different sample strip, can select sample panel and the cladding plate of different size.By spring, sample strip is pressed on sample panel reliably, guarantees the stability of sample position.Greatly improve the efficiency of experimentation, guaranteed the stability of data simultaneously.
3, sample bin is provided with nitrogen inlet, can easily nitrogen be incorporated in sample bin, in order to humidity in storehouse is dropped to the regulation requirement fast, and the use amount of also having saved nitrogen simultaneously.
The utlity model has in a word sample and install succinctly fast, the measuring accuracy advantages of higher, can better guarantee the accuracy of Terahertz experimental system data acquisition to improve conventional efficient.
The accompanying drawing explanation
Fig. 1 is the front schematic view of the utility model Terahertz system sample sampling apparatus;
Fig. 2 is the schematic top plan view of the utility model Terahertz system sample sampling apparatus;
Fig. 3 is the front schematic view of the utility model Terahertz system sample sampling apparatus longitudinal sliding motion mechanism;
Fig. 4 is the schematic top plan view of the utility model Terahertz system sample sampling apparatus longitudinal sliding motion mechanism;
Fig. 5 is the utility model Terahertz system sample sampling apparatus longitudinal rail scheme of installation;
Fig. 6 is the utility model Terahertz system sample sampling apparatus transverse sliding mechanism front schematic view;
Fig. 7 is the utility model Terahertz system sample sampling apparatus transverse sliding mechanism schematic top plan view;
Fig. 8 is the utility model Terahertz system sample sampling apparatus sample bin front schematic view;
Fig. 9 is the utility model Terahertz system sample sampling apparatus sample bin schematic top plan view;
Figure 10 is the utility model Terahertz system sample sampling apparatus specimen holder front view (FV);
Figure 11 is the utility model Terahertz system sample sampling apparatus specimen holder side schematic view;
Figure 12 is the utility model Terahertz system experimental device system architecture schematic diagram;
Figure 13 is the utility model workflow diagram.
In figure: left stepper motor 1, right stepper motor 2, top board 3, left plate 4, left screw mandrel 5, left straight line optical axis 6, specimen holder 7, right plate 8, right screw mandrel 9, right straight line optical axis 10, transverse sliding mechanism 11, approach switch 12, lifting table 13, left straight line optical axis bearing 14, longitudinal sliding motion mechanism 15, right straight line optical axis bearing 16, base 17, electric machine controller 18, left rail cushion block 19, vertical stepper motor 20, right guide rail cushion block 21, left line slideway 22, left linear slider 23, vertical platform 24, vertical platform contiguous block I 25, right straight-line guide rail slide block 26, right line slideway 27, slide block coupling bolt 28, guide rail coupling bolt 29, cushion block coupling bolt 30, vertical platform contiguous block II 31, vertical screw mandrel bolt 32, vertical screw mandrel 33, end bearing 34 before vertical screw mandrel, vertical shaft coupling 35, vertical motor contiguous block 36, cross lead screw terminal shaft bearing 37, laterally the bearing terminal shaft holds 38, cross lead screw 39, horizontal platform 40, horizontal platform contiguous block 41, cross lead screw bolt 42, end bearing block 43 before cross lead screw, end bearing 44 before cross lead screw, horizontal shaft coupling 45, cross motor contiguous block 46, cross motor 47, cross motor contiguous block bolt 48, rear rail cushion block 49, front linear slider 50, fromer rail cushion block 51, specimen holder lid 52, sample bin 53, sample bin support 54, specimen holder base plate 55, sample bin air intake opening 56, sample bin support bracket bolt 57, sample cap bolt 58, cladding plate 59, cladding plate bolt 60, sample panel 61, sample 62, cladding plate spring 63, cladding plate setting nut 64, femto-second laser 65, collimation lens I 66, half slide 67, beam splitter 68, collimation lens II 69, catoptron I 70, differential detector I 71, differential detector II 72, wollaston prism 73, quarter-wave plate 74, ZnTe crystal 75, Si mirror 76, paraboloidal mirror I 77, paraboloidal mirror II 78, sample sampling apparatus 79, paraboloidal mirror III 80, paraboloidal mirror IV 81, GaAs crystal 82, catoptron II 83, catoptron III 84, catoptron IV 85, chopper 86, lock-in amplifier 87, computing machine 88, nitrogen cylinder 89, humidity sensor 90, electric platforms 91.
Embodiment
Below in conjunction with accompanying drawing, the utility model is described in further detail.
As shown in Figure 1 and Figure 2, a kind ofly for cancer of the stomach, detect Terahertz system sample sampling apparatus, the left side of left stepper motor 1 and right stepper motor 2, top board has been installed on top board 3 left plate 4 has been installed, right plate 8 has been installed on the right side of top board; Base 17 has been installed in the bottom of left plate 4 and right plate 8; Approach switch 12 has been installed in the middle and lower part of left plate, and four right angle ends of base 17 have been installed the straight line optical axis, i.e. two left straight line optical axises 6 and two right straight line optical axises 10; Longitudinal translation mechanism 15 and laterial translation mechanism 11 have been installed respectively on lifting table 13, specimen holder 7 has been installed on laterial translation mechanism 11, the right-hand member of base plate 17 is provided with electric machine controller 18, two left straight line optical axis bearings 14 and two right straight line optical axis bearings 16 have been installed respectively in the two ends, left and right of lifting table 13, one end of left straight line optical axis 6, right straight line optical axis 10 is separately fixed at left end and the right-hand member of top board 3 lower surfaces, the other end is fixed on base 17 after passing the left straight line optical axis bearing 14 and right straight line optical axis bearing 16 on lifting table 13; The end of left screw mandrel 5, right screw mandrel 9 is separately fixed at left end and the right-hand member of top board 3 lower surfaces, and the other end is fixed on base 17 through the through hole on lifting table 13; And left screw mandrel 5, left straight line optical axis 6, right screw mandrel 9, right straight line optical axis 10 and left plate 4, right plate 8 are parallel;
As shown in Figure 3, Figure 4, longitudinal translation mechanism 15 comprises lifting table 13, left rail cushion block 19, vertical stepper motor 20, right guide rail cushion block 21, left line slideway 22, left linear slider 23, vertical platform 24, right straight-line guide rail slide block 26, right line slideway 27; Lifting table 13 upper surfaces are equipped with on the left rail cushion block 19 and right guide rail cushion block 21; Left line slideway 22 is housed on left rail cushion block 19, and left line slideway 22 is provided with left linear slider 23, and left linear slider 23 is arranged on vertical platform 24 lower surfaces; Right guide rail cushion block 21 is provided with right line slideway 27, and right line slideway 27 is provided with right linear slider 26, and right linear slider 26 is arranged on vertical platform 24 lower surfaces; Vertically platform contiguous block I 25 is connected with vertical platform 24 by vertical screw mandrel bolt 32 with vertical platform contiguous block II 36, and vertically stepper motor 20 is arranged on vertical platform contiguous block I 25 and vertical platform contiguous block II 36; Vertically the front end of stepper motor 20 is equipped with vertical shaft coupling 35, and vertical shaft coupling 35 is connected with an end of vertical screw mandrel 33 by end bearing 34 before vertical screw mandrel, and vertically the other end of screw mandrel 33 is connected with vertical platform contiguous block.
As shown in Figure 5, in described longitudinal sliding motion mechanism 15, lifting table 13 is connected with left rail cushion block 19 by cushion block coupling bolt 30, and left rail cushion block 19 passes through guide rail coupling bolt 29 and is connected with left line slideway 22.Left linear slider 23 is housed on left line slideway 22, and left linear slider 23 is connected with vertical platform 24 by slide block coupling bolt 28.
As shown in Figure 6, Figure 7, laterial translation mechanism 11 comprise cross lead screw terminal shaft bearing 37, laterally the bearing terminal shaft hold 38, end bearing 44 before end bearing block 43, cross lead screw before cross lead screw 39, horizontal platform 40, horizontal platform contiguous block 41, cross lead screw bolt 42, cross lead screw, laterally shaft coupling 45, cross motor contiguous block 46, cross motor 47, cross motor contiguous block bolt 48, rear rail cushion block 49, transverse slider 50, fromer rail cushion block 51;
Vertically on platform 24, be fixedly installed cross lead screw terminal shaft bearing 37, the front end bearing block 43 of cross lead screw and cross motor contiguous block 46, cross lead screw terminal shaft bearing 37 is provided with horizontal bearing terminal shaft and holds 38, horizontal bearing terminal shaft holds 38 and fixes with an end of cross lead screw 39, after the front end bearing 44 of cross lead screw of the other end of cross lead screw 39 through installation on the front end bearing block 43 of cross lead screw, with an end of horizontal shaft coupling 45, be connected, laterally the other end of shaft coupling 45 is connected with the output shaft of cross motor 47; Cross motor 47 is fixedly installed on cross motor contiguous block 46, and cross motor contiguous block 46 is connected with vertical platform 24 by cross motor contiguous block bolt 48.Vertically rear portion and the front portion of platform are respectively equipped with rear rail cushion block 49 and fromer rail cushion block 51, and rear rail cushion block 49 is connected with horizontal platform 40 by transverse slider 50 with fromer rail cushion block 51.
As shown in Figure 8, Figure 9, specimen holder 7 comprises specimen holder lid 52, sample bin 53, sample bin support 54, specimen holder base plate 55, sample bin air intake opening 56, sample bin support bracket bolt 57; On specimen holder base plate 55, by sample bin support bracket bolt 57, with sample bin support 54 lower ends, be connected, sample bin support 54 upper ends are provided with sample bin 53, the lower surface of sample bin 53 has sample bin air intake opening 56, upper surface is provided with specimen holder lid 52, be provided with sample panel 61, cladding plate 59 in sample bin 53, cladding plate 59 is arranged on the front portion of sample panel 61, and a side of sample bin 53 is provided with humidity sensor 87.
As shown in Figure 10, Figure 11, be provided with sample panel 61, cladding plate 59 in sample bin 53, and cladding plate 59 is connected with sample panel 61 by cladding plate bolt 60, sample panel 61 is positioned at specimen holder and covers 52 bottoms, its front portion is provided with sample 62, and the front portion of sample 62 is provided with cladding plate 59, and cladding plate 59 is pressed on sample 62 by cladding plate spring 63, the right side of cladding plate spring 63 is provided with cladding plate setting nut 64, and cladding plate setting nut 64 and cladding plate spring 63 all are contained on cladding plate bolt 60.
As shown in figure 12, described collection light path comprises electric machine controller 18, femto-second laser 65, collimation lens I 66, half slide 67, beam splitter 68, collimation lens II 69, catoptron I 70, differential detector I 71, differential detector II 72, wollaston prism 73, quarter-wave plate 74, ZnTe crystal 75, Si mirror 76, paraboloidal mirror I 77, paraboloidal mirror II 78, sample sampling apparatus 79, paraboloidal mirror III 80, paraboloidal mirror IV 81, GaAs crystal 82, catoptron II 83, catoptron III 84, catoptron IV 85, chopper 86, lock-in amplifier 87, computing machine 88, electric machine controller 18, electric platforms 91,
The laser that femto-second laser 65 produces is by collimation lens I 66 and half slide 67 is rear by beam splitter 68, is divided into the pumping light path and surveys light path, the pumping light path arrives catoptron IV 85 by chopper 86 incide catoptron I 70 after collimation lens II 69 after, laser is through catoptron IV 85, catoptron II 83, arrive paraboloidal mirror III 80 by GaAs crystal 82 after catoptron III 84, arrive paraboloidal mirror II 78 after passing the sample 62 in sample sampling apparatus 79 afterwards after 81 refractions of paraboloidal mirror IV, the pumping light path is through paraboloidal mirror II 78, paraboloidal mirror I 77, Si mirror 76 arrives ZnTe crystal 75, surveying light path converges with the pumping light path through after Si mirror 76 reflections, arriving ZnTe crystal 75.Laser after converging arrives computing machine 88 through quarter-wave plate 74, wollaston prism 73, differential detector I 71, differential detector II 72, lock-in amplifier 87, nitrogen cylinder 89 is connected in sample sampling apparatus 79 by tracheae, and whole process is controlled electric platforms 91 by electric machine controller 18 and completed.
The THz system of the titanium sapphire femto-second laser that the terahertz time-domain spectroscopy system and device is manufactured by U.S. Coherent company and the development of U.S. Zomega company is formed.Laser pulse is as pump light source and probe source.Femto-second laser pulse is divided into pumping pulse and direct impulse by beam splitter after half-wave plate.Pumping pulse, at the substrate surface that incides the antenna transmission utmost point after optical delay line, covers the gap between two electrodes.Femto-second laser pulse excites GaAs plane of crystal charge carrier, under the driving of AC bias high pressure, moves, and the THz pulse (terahertz pulse) of radiation.Direct impulse is beaten on Si mirror through Si mirror, through the reflection of Si mirror, beat on the ZnTe crystal, on the ZnTe crystal with reflect through paraboloidal mirror I, paraboloidal mirror II, paraboloidal mirror III and paraboloidal mirror IV and see through sample and be loaded with the THz wave conllinear of sample message.The detection light path that is loaded with sample message finally is divided into two components that polarization direction is vertical by wollaston prism after quarter-wave plate, finally by differential detector I and differential detector II, demodulates the information of sample by the strength difference of measuring two polarized components.Measuring-signal input computing machine after lock-in amplifier amplifies obtains time-domain spectroscopy.
The utility model using method, comprise the steps:
Step (1). select the pore size of sample panel and cladding plate according to the diameter of sample sheet.
Step (2). sample, as between sample panel and cladding plate, then is positioned over to sample bin by sample panel.
Step (3). nitrogen tube is linked into to the air intake opening place of sample bin, is filled with nitrogen to reduce humidity to 3% in storehouse.
Step (4). regulate the residing position of sample bin by electric machine controller, make the center at THz wave focus place.
Step (5). fix the pumping light path and survey all optical device on light path according to the travel path of light path, guarantee laser beam successively the center by each optical device and light path at the same level height.
Step (6). regulate electric platforms, when stepper motor is moved, light path remains unchanged.Make the pumping light path of terahertz pulse simultaneously and survey the light path equivalent optical path, if unequal, by the position that changes catoptron II and catoptron IV, making up the optical path difference between the two.
Step (7). confirm that laser beam is by collimation lens I, collimation lens Ⅱ center, if exist deviation to be regulated by catoptron II, catoptron III.THz wave transmitting crystal GaAs will strictly be placed on the focus of paraboloidal mirror III, and in like manner electro-optic detection crystal ZnTe also must be placed on the focus of paraboloidal mirror I.
Step (8). just can carry out the measurement of experimental data after having debugged the light path of system.Can pass through motor controller controls in experimentation, so that each some place of sample is scanned with sampled data.
As shown in figure 13, implementation process of the present utility model is as follows:
At first according to diameter selection sample panel 61 and the cladding plate 59 of sample 62, secondly according to thickness of sample 62, regulate cladding plate setting nut 64 before experiment, make cladding plate spring 63 sample 62 to be pressed on sample panel 61 by cladding plate 59.Then the nitrogen in nitrogen cylinder 89 is entered into to sample bin 53 by sample bin air intake opening 56.Then the humidity value of measuring in sample bin 53 by humidity sensor 90, when the humidity value in sample bin 53 is less than 3%, regulate the residing position of sample bin 53 by electric machine controller 18, makes it be in the laser spot place.Fix optical device all on light path according to the light path route afterwards.Regulate electric platforms 91 and make Terahertz light path and equivalent optical path.Determine that the laser beam route passes through the center of each device, then open computing machine 88, the operation sampling routine carries out the collection of experimental data.
Claims (1)
1. one kind is detected Terahertz system sample sampling apparatus for cancer of the stomach, it is characterized in that comprising apparatus structure and gathers light path; The left side of left stepper motor and right stepper motor, top board has been installed in apparatus structure on top board left plate has been installed, right plate has been installed on the right side of top board; Base has been installed in the bottom of left plate and right plate; Approach switch has been installed in the middle and lower part of left plate, and four right angle ends of base have been installed the straight line optical axis, i.e. two left straight line optical axises and two right straight line optical axises; Longitudinal translation mechanism and laterial translation mechanism have been installed respectively on lifting table, specimen holder has been installed on laterial translation mechanism, the right-hand member of base plate is provided with electric machine controller, two left straight line optical axis bearings and two right straight line optical axis bearings have been installed respectively in the two ends, left and right of lifting table, one end of left straight line optical axis, right straight line optical axis is separately fixed at left end and the right-hand member of top board lower surface, the other end is fixed on base after passing the left straight line optical axis bearing and right straight line optical axis bearing on lifting table; The end of left screw mandrel, right screw mandrel is separately fixed at left end and the right-hand member of top board lower surface, and the other end is fixed on base through the through hole on lifting table; And left screw mandrel, left straight line optical axis, right screw mandrel, right straight line optical axis and left plate, right plate are parallel;
Longitudinal translation mechanism comprises lifting table, left rail cushion block, left line slideway, left linear slider, vertical platform, vertical stepper motor, right guide rail cushion block, right line slideway, right straight-line guide rail slide block; The lifting table upper surface is equipped with on the left rail cushion block and right guide rail cushion block; Left line slideway is housed on the left rail cushion block, and left line slideway is provided with left linear slider, and left linear slider is arranged on vertical platform lower surface; Right guide rail cushion block is provided with right line slideway, and right line slideway is provided with right linear slider, and right linear slider is arranged on vertical platform lower surface; The lifting table upper surface is provided with vertical motor contiguous block, vertically on the motor contiguous block, vertical stepper motor is housed, vertically the front end of stepper motor is equipped with vertical shaft coupling, vertically shaft coupling is connected with an end of vertical screw mandrel by end bearing before vertical screw mandrel, vertically on the other end of screw mandrel, be provided with vertical screw mandrel bolt, vertically the screw mandrel bolt is connected with vertical platform with vertical platform contiguous block II by vertical platform contiguous block I;
In described longitudinal sliding motion mechanism, lifting table is connected with the left rail cushion block by vertical coupling bolt, and the left rail cushion block passes through the guide rail coupling bolt and is connected with left line slideway; Left linear slider is housed on left line slideway, and left linear slider is connected with vertical platform by the slide block coupling bolt;
Laterial translation mechanism comprise cross lead screw terminal shaft bearing, laterally the bearing terminal shaft hold, end bearing before end bearing block, cross lead screw before cross lead screw, horizontal platform, horizontal platform contiguous block, cross lead screw bolt, cross lead screw, laterally shaft coupling, cross motor contiguous block, cross motor, cross motor contiguous block bolt, rear rail cushion block, transverse slider, fromer rail cushion block; Vertically on platform, be fixedly installed cross lead screw terminal shaft bearing, the front end bearing block of cross lead screw and cross motor contiguous block, cross lead screw terminal shaft bearing is provided with horizontal bearing terminal shaft and holds, laterally the bearing terminal shaft holds with an end of cross lead screw and fixes, after the other end of cross lead screw passes the front end bearing of cross lead screw of installing on the front end bearing block of cross lead screw, with an end of horizontal shaft coupling, be connected, laterally the other end of shaft coupling is connected with the output shaft of cross motor; Cross motor is fixedly installed on the cross motor contiguous block, and the cross motor contiguous block is connected with vertical platform by cross motor contiguous block bolt; Vertically rear portion and the front portion of platform are respectively equipped with rear rail cushion block and fromer rail cushion block, and the rear rail cushion block is connected with horizontal platform by transverse slider with the fromer rail cushion block;
Specimen holder comprises specimen holder lid, sample bin, sample bin air intake opening, sample bin support, sample bin support bracket bolt, specimen holder base plate; On the specimen holder base plate, by the sample bin support bracket bolt, with sample bin support lower end, be connected, sample bin support upper end is provided with sample bin, the lower surface of sample bin has the sample bin air intake opening, upper surface is provided with the specimen holder lid, be provided with sample panel, cladding plate in sample bin, cladding plate is arranged on the front portion of sample panel, and a side of sample bin is provided with humidity sensor; Be provided with sample panel, cladding plate in sample bin, and cladding plate is connected with sample panel by the cladding plate bolt, sample panel is positioned at specimen holder lid bottom, its front portion is provided with sample, the front portion of sample is provided with cladding plate, cladding plate is pressed on sample by the cladding plate spring, and the right side of cladding plate spring is provided with the cladding plate setting nut, and cladding plate setting nut and cladding plate spring all are contained on the cladding plate bolt;
Described collection light path comprises electric machine controller, femto-second laser, the collimation lens I, half slide, beam splitter, the collimation lens II, the catoptron I, the differential detector I, the differential detector II, wollaston prism, quarter-wave plate, the ZnTe crystal, Si mirror, the paraboloidal mirror I, the paraboloidal mirror II, the sample sampling apparatus, the paraboloidal mirror III, the paraboloidal mirror IV, the GaAs crystal, the catoptron II, the catoptron III, the catoptron IV, chopper, lock-in amplifier, computing machine, electric machine controller, electric platforms, the laser that femto-second laser produces is divided into two-way by beam splitter after by collimation lens I and half slide, first via laser arrives the catoptron IV by chopper incide the catoptron I after the collimation lens II after, laser arrives the paraboloidal mirror III by the GaAs crystal after catoptron IV, catoptron II, catoptron III, arrive the paraboloidal mirror II after passing sample and sample sampling apparatus afterwards after the refraction of paraboloidal mirror IV, laser is through paraboloidal mirror II, paraboloidal mirror I, Si mirror, ZnTe crystal, the second road laser arrives the ZnTe crystal after reflecting through Si mirror and first via laser converges, laser after converging arrives computing machine through quarter-wave plate, wollaston prism, differential detector I, differential detector II, lock-in amplifier, nitrogen cylinder is connected in the sample sampling apparatus by tracheae, and whole process is completed by the motor controller controls electric platforms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320296107 CN203350171U (en) | 2013-05-27 | 2013-05-27 | Terahertz system sample sampling device for stomach cancer test |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320296107 CN203350171U (en) | 2013-05-27 | 2013-05-27 | Terahertz system sample sampling device for stomach cancer test |
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| Publication Number | Publication Date |
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| CN203350171U true CN203350171U (en) | 2013-12-18 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201320296107 Expired - Fee Related CN203350171U (en) | 2013-05-27 | 2013-05-27 | Terahertz system sample sampling device for stomach cancer test |
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| CN (1) | CN203350171U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103323420A (en) * | 2013-05-27 | 2013-09-25 | 杭州电子科技大学 | Sampling device for stomach cancer detection terahertz system and its use method |
| CN104665772A (en) * | 2015-02-13 | 2015-06-03 | 上海理工大学 | All-optical fiber type device for detecting and treating superficial cancer cells |
-
2013
- 2013-05-27 CN CN 201320296107 patent/CN203350171U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103323420A (en) * | 2013-05-27 | 2013-09-25 | 杭州电子科技大学 | Sampling device for stomach cancer detection terahertz system and its use method |
| CN104665772A (en) * | 2015-02-13 | 2015-06-03 | 上海理工大学 | All-optical fiber type device for detecting and treating superficial cancer cells |
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