CN203200277U - Biological reactor - Google Patents
Biological reactor Download PDFInfo
- Publication number
- CN203200277U CN203200277U CN 201320144257 CN201320144257U CN203200277U CN 203200277 U CN203200277 U CN 203200277U CN 201320144257 CN201320144257 CN 201320144257 CN 201320144257 U CN201320144257 U CN 201320144257U CN 203200277 U CN203200277 U CN 203200277U
- Authority
- CN
- China
- Prior art keywords
- tank body
- bio
- stir shaft
- stirring shaft
- shaft
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- Mixers Of The Rotary Stirring Type (AREA)
Abstract
The utility model relates to a biological reactor. The biological reactor comprises a tank body and a mechanical stirring device which is arranged on the bottom of the tank body, wherein the tank body is made of stainless steel or glass; the mechanical stirring device comprises a stirring shaft and a stirrer which is connected with the stirring shaft in a transmission manner, wherein the stirring shaft is inserted from the shaft center of a housing; the rotary shaft and the housing are sealed; the length of the stirring shaft is 3/5-3/4 the height of the tank body; the stirring shaft is hollow; a plurality of ventilating holes are formed on the surface of the stirring shaft; one ventilating tube extending from the tank body is inserted to the cavity of the stirring shaft. Besides, at least two stirrers are arranged on the stirring shaft, wherein the lowest stirrer is an anchor stirrer; and at least one propeller is arranged above the anchor stirrer. The biological reactor can be used for enabling dissolved oxygen in the tank body to be uniformly distributed, improving dissolved oxygen amount and dissolved oxygen utilization rate. Meanwhile, the stirring can be sufficient and uniform, and a good mass transfer effect and a mixing effect are achieved.
Description
Technical field
The utility model relates to a kind of bio-reactor, is specifically related to a kind of bio-reactor with breather, belongs to the cell culture technology field.
Background technology
Bio-reactor is the nucleus equipment of extensive animal cell culture.Need certain oxygen depletion in cell cultivation process, therefore using bio-reactor to carry out in the animal cell large-scale cultivation, passing into gas is the important sources of Growth of Cells and the required dissolved oxygen of metabolism.And the ventilating mode of bio-reactor directly affects dissolved oxygen amount and dissolved oxygen utilization ratio etc., and cell cultures is had considerable influence.
CN202730136 U has announced a kind of bio-reactor, and ventpipe is that the side from tank body extend into the tank body inner bottom part, and air flow is limited, and mainly concentrates on tank base, dissolved oxygen skewness in the tank body.In addition, in this patent, employing be turbine type agitator, and only have one, so that the reactor top can not fully be stirred.
Summary of the invention
The purpose of this utility model is to overcome above-mentioned shortcoming, and a kind of dissolved oxygen, well-beaten reactor of evenly distributing is provided.
The technical solution of the utility model is as follows:
A kind of bio-reactor, comprise tank body and the mechanical stirring device of being located at described tank base, tank body is stainless steel or glass, mechanical stirring device comprises stir shaft and the agitator that is in transmission connection with it, and stir shaft inserts from the axle center of shell, seals between rotating shaft and the shell, the length of stir shaft is the 3/5-3/4 of tank body height, stir shaft is hollow form, and the surface is provided with a plurality of breeder tubes, and a ventpipe that stretches into outside tank body inserts in the cavity of stir shaft.
In addition, have two agitators on the stir shaft at least, the agitator of below is anchor stirrer, and its external diameter is the 60%-75% of described tank body internal diameter.Establish at least one propeller mixer above anchor stirrer, its external diameter is the 55%-65% of described tank body internal diameter.
The beneficial effects of the utility model are:
1, the length that stir shaft is set is the 3/5-3/4 of tank body height, and stir shaft is designed to hollow form, and the surface is provided with a plurality of breeder tubes, and ventpipe inserts in the cavity of stir shaft, dissolved oxygen in the tank body is evenly distributed, improve dissolved oxygen amount and dissolved oxygen utilization ratio.
2, the mechanical type that adopts of the utility model stirs, and anchor stirrer is put in the below, and is provided with above it at least one propeller mixer, can make to stir fully, evenly, even reactor volume is large, also can reach good mass transfer and mixed effect.
Description of drawings
Below in conjunction with drawings and Examples the utility model is further specified.
Fig. 1 is that master of the present utility model looks schematic diagram;
Among the figure, 1, tank body, 2, propeller mixer, 3, anchor stirrer,
4, stir shaft, 5, breeder tube, 6, ventpipe.
Embodiment
Further specify embodiment of the present utility model below in conjunction with accompanying drawing, but this should be interpreted as that the scope of this bright above-mentioned theme only limits to following example, all technology that realizes based on the utility model foregoing all belong to scope of the present utility model.
Embodiment 1
A kind of bio-reactor, comprise tank body 1 and the mechanical stirring device of being located at described tank base, tank body is stainless steel, mechanical stirring device comprises stir shaft 4 and the agitator that is in transmission connection with it, and stir shaft inserts from the axle center of shell, seals between rotating shaft and the shell, the length of stir shaft 4 is 3/5 of tank body height, stir shaft is hollow form, and the surface is provided with 5, ventpipes that stretch into of a plurality of breeder tubes 6 and inserts in the cavity of stir shaft outside tank body.
In addition, have two agitators on the stir shaft at least, the agitator of below is anchor stirrer 3, and its external diameter is 60% of described tank body internal diameter.Establish a propeller mixer 2 above anchor stirrer, its external diameter is 55% of described tank body internal diameter.
Embodiment 2
A kind of bio-reactor, comprise tank body 1 and the mechanical stirring device of being located at described tank base, tank body is stainless steel, mechanical stirring device comprises stir shaft 4 and the agitator that is in transmission connection with it, and stir shaft inserts from the axle center of shell, seals between rotating shaft and the shell, the length of stir shaft 4 is 3/4 of tank body height, stir shaft is hollow form, and the surface is provided with 5, ventpipes that stretch into of a plurality of breeder tubes 6 and inserts in the cavity of stir shaft outside tank body.
In addition, have two agitators on the stir shaft at least, the agitator of below is anchor stirrer 3, and its external diameter is 75% of described tank body internal diameter.Establish two propeller mixers 2 above anchor stirrer, its external diameter is 65% of described tank body internal diameter.
Claims (8)
1. bio-reactor, comprise tank body and the mechanical stirring device of being located at described tank base, described mechanical stirring device comprises stir shaft and the agitator that is in transmission connection with it, stir shaft inserts from the axle center of shell, seal between rotating shaft and the shell, it is characterized in that stir shaft is hollow form, the surface is provided with several breeder tubes, and a ventpipe that stretches into outside tank body inserts in the cavity of stir shaft.
2. bio-reactor according to claim 1, the length that it is characterized in that stir shaft is the 3/5-3/4 of tank body height.
3. bio-reactor according to claim 1 is characterized in that having at least on the stir shaft two agitators.
4. bio-reactor according to claim 3 is characterized in that the agitator of below is anchor stirrer.
5. bio-reactor according to claim 4, the external diameter that it is characterized in that anchor stirrer is the 60%-75% of described tank body internal diameter.
6. bio-reactor according to claim 5 is characterized in that establishing at least one propeller mixer above the anchor stirrer.
7. bio-reactor according to claim 6, the external diameter that it is characterized in that propeller mixer is the 55%-65% of described tank body internal diameter.
8. bio-reactor according to claim 1 is characterized in that tank body is stainless steel or glass.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320144257 CN203200277U (en) | 2013-03-27 | 2013-03-27 | Biological reactor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320144257 CN203200277U (en) | 2013-03-27 | 2013-03-27 | Biological reactor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203200277U true CN203200277U (en) | 2013-09-18 |
Family
ID=49144405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201320144257 Expired - Fee Related CN203200277U (en) | 2013-03-27 | 2013-03-27 | Biological reactor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203200277U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103875844A (en) * | 2014-04-13 | 2014-06-25 | 周午贤 | Improved green tea enzymolysis device |
| CN103891965A (en) * | 2014-04-13 | 2014-07-02 | 周午贤 | Green-tea enzymolysis device |
| CN104188738A (en) * | 2014-08-14 | 2014-12-10 | 卢建熙 | Multi-functional internal bone generator |
| CN108410734A (en) * | 2018-05-17 | 2018-08-17 | 江苏弗洛瑞生物工程设备有限公司 | A kind of biological reactor for cell culture |
-
2013
- 2013-03-27 CN CN 201320144257 patent/CN203200277U/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103875844A (en) * | 2014-04-13 | 2014-06-25 | 周午贤 | Improved green tea enzymolysis device |
| CN103891965A (en) * | 2014-04-13 | 2014-07-02 | 周午贤 | Green-tea enzymolysis device |
| CN103875844B (en) * | 2014-04-13 | 2015-07-01 | 周午贤 | Improved green tea enzymolysis device |
| CN103891965B (en) * | 2014-04-13 | 2015-09-23 | 周午贤 | Green tea enzymolysis device |
| CN104188738A (en) * | 2014-08-14 | 2014-12-10 | 卢建熙 | Multi-functional internal bone generator |
| CN104188738B (en) * | 2014-08-14 | 2018-04-27 | 卢建熙 | Multifunctional body in-seam generator |
| CN108410734A (en) * | 2018-05-17 | 2018-08-17 | 江苏弗洛瑞生物工程设备有限公司 | A kind of biological reactor for cell culture |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130918 Termination date: 20160327 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |