CN202822869U - Multifunctional liquid phase preparation dynamic axial compression column - Google Patents
Multifunctional liquid phase preparation dynamic axial compression column Download PDFInfo
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- CN202822869U CN202822869U CN 201220540691 CN201220540691U CN202822869U CN 202822869 U CN202822869 U CN 202822869U CN 201220540691 CN201220540691 CN 201220540691 CN 201220540691 U CN201220540691 U CN 201220540691U CN 202822869 U CN202822869 U CN 202822869U
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- liquid phase
- axial compression
- dynamic axial
- preparation
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Abstract
The utility model discloses a multifunctional liquid phase preparation dynamic axial compression column comprising a conversion column, a preparation column and a lower end cover. The bottom end of the conversion column is fixedly connected with the top end of the preparation column by a bolt, and the bottom end of the preparation column is fixedly connected with the lower end cover by a chain type lathedog. A seal ring, a distributor and a filter plate are arranged in the lower end cover, a liquid phase pipe outlet is arranged on the bottom of the lower end cover, the distributor is arranged above the liquid phase pipe outlet, and the filter plate is arranged on the distributor. By utilizing the multifunctional liquid phase preparation dynamic axial compression column, the entire preparation column can be filled by fillers so that stability of column efficiency can be kept and waste of expensive fillers is reduced. The conversion column can be disassembled through arrangement and the fillers can be fast loaded and unloaded so that the preparation time of a filled column is saved and the work efficiency is improved.
Description
Technical field
The utility model relates to a kind of compression post, relates in particular to a kind of multi-functional liquid phase and prepares dynamic axial compression column, belongs to the chromatographic isolation preparation field.
Background technology
Chromatographic separation technology is one of topmost separating and purifying technology in the active constituents of medicine isolation technics, it develops into preparation and production scale from analytical scale, and developed into the particularly important method of active ingredient of Chinese herbs of the standby medicine of large-scale separation, be mainly used in the separation of various ingredients, utilize the efficient adsorption filler to adopt the mode of high pressure, make the efficient adsorption filler give play to best result from efficient, the high performance liquid preparative chromatography post of present domestic design, majority is fixing upper lower flange mode, and filler self can not be subject to continuing high pressure.Be difficult to keep continuing closely realizing its efficient separating power.The dynamic axial compression technology is unique technology that can keep the good separation effect in the column chromatography of various scales.
Say that from specification the larger pillar of diameter is also just longer, separate effect when doing like this preparation better, to use very meticulous filler when separating the very approaching component of several properties, when carrying out small lot preparation separation, or divide too busy to get away at additive method, when consideration need be carried out lab scale with preparation, all will use the preparation short column, in general preparing short column all is that internal diameter is the preparative column of 5cm;
If the preparative column of 5cm dress is adopted identical preparation method with normal preparative column, finish the preparation of a pin during preparation and want the long period, need not from separating effect, because for diameter 5cm pillar, 20cm length just can reach separating effect, if use the long column of 65cm, the waste to expensive filler on the one hand, the aspect is temporal waste in addition, same effect, and cost will be high a lot; Fill in addition column pressure and also be difficult for meeting the demands, also can have the problem of the discontented pillar of dress simultaneously, be difficult to reach separating effect; Because sample feeding pipe will enter filler by distributor during preparation, reservation regular hour target component and impurity just can be separated in filler, if do not fill, sample solution just can not enter filler equably, so styletable mouth and filler face exist the space just can not be prepared.
Summary of the invention
The purpose of this utility model provides a kind of charging and discharging convenience, a kind of multi-functional liquid phase simple in structure to prepare dynamic axial compression column with regard to being in order to address the above problem.
The utility model is achieved through the following technical solutions above-mentioned purpose:
The utility model comprises transition mast, preparative column and bottom end cover, and the bottom of described transition mast and the top of described preparative column are bolted to connection, and the bottom of described preparative column is fixedly connected with by the chain clip with described bottom end cover.
Further, be provided with sealing ring, distributor and filter plate in the described bottom end cover, described end cap bottom is provided with the liquid phase outlet spout, and described distributor is arranged on the top of described liquid phase outlet spout, is provided with filter plate on the described distributor.
Particularly, the column length of described transition mast is 30cm.
Further, the column length of described preparative column is 23cm.
As preferred plan, the inwall glossiness of described preparative column and described transition mast is less than 0.02 micron.
As preferentially, the inwall glossiness of described preparative column and described transition mast equals 0.02 micron.
Particularly, described transition mast column casing thickness is 0.8-1cm.
The beneficial effects of the utility model are:
The utility model can make filler fill densely whole preparative column, keeps the post effect stable, reduces the waste to expensive filler, by detachable transition mast is set, can carry out rapidly charging and the discharging of filler, save the preparation time of filled column, improve operating efficiency.
Description of drawings
Fig. 1 is that multi-functional liquid phase described in the utility model prepares the structural representation in the dynamic axial compression column;
Fig. 2 is that multi-functional liquid phase described in the utility model prepares the scheme of installation in the dynamic axial compression column;
Fig. 3 is the structural representation that multi-functional liquid phase described in the utility model prepares the preparative column in the dynamic axial compression column.
Among the figure: 1-piston rod, 2-piston, 21-through hole, the upper bolt of 3-, 4-transition mast, 5-bolt, the 6-preparative column, 7-chain clip, 8-bottom end cover, 81-sealing ring, 83-distributor, 82-filter plate, the static preparation of 9-end cap, 10-support, 11-liquid phase outlet spout, 12-frame, 13-upper end cover.
The specific embodiment
The utility model is described in further detail below in conjunction with accompanying drawing:
As shown in Figure 1, the utility model comprises transition mast 4, preparative column 6 and bottom end cover 8, the bottom of described transition mast 4 is fixedly connected with by bolt 5 with the top of described preparative column 6, the bottom of described preparative column 6 is fixedly connected with by chain clip 7 with described bottom end cover 8, be provided with sealing ring 81 in the bottom end cover 8, distributor 83 and filter plate 82, bottom end cover 8 bottoms are provided with liquid phase outlet spout 11, distributor 83 is arranged on the top of liquid phase outlet spout 11, be provided with filter plate 82 on the distributor 83, the column length of transition mast 4 is 30cm, the column length of preparative column 6 is 23cm, and the inwall glossiness of preparative column 6 and transition mast 4 is less than or equal to 0.02 micron, and transition mast 4 column casing thickness are 0.8-1cm.
As shown in Figure 2, the course of work of the present utility model is as follows: the preparative column take internal diameter as 5cm is example, piston 2 with 5cm preparative column 6 couplings is installed on the piston rod 1, and be fixedly connected with by through hole 21, then transition mast 4 upper ends are fixed on the frame 12 by upper bolt 3, the preparative column 6 of lower port and 5cm to be installed mates fixing, be fixedly connected with by bolt 5, set pressure 50bar, pour ready filler homogenate into dress post funnel, cover upper end cover 13 rear startup dress posts, after the dress post is finished, filler approximately installs to the position of 10cm on the transition mast 4, then unloads post.
As shown in Figure 3, preparative column 6 also can use as static post separately, after taking off transition mast 4, be fixedly connected with respectively upper static preparation end cap 9 and support 10 by bolt, be connected with sample feeding pipe 14 on the static preparation end cap 9, the raw material of preparation evenly enters the filler from sample feeding pipe 14 through upper static preparation end cap 9, realize the separation of component through certain retention time, through going out sample pipe 11, carry out the reception of component separating liquid, just can finish the preparation separation process.
Claims (7)
1. a multi-functional liquid phase prepares dynamic axial compression column, comprises preparative column and bottom end cover, it is characterized in that:
Also comprise transition mast, the bottom of described transition mast and the top of described preparative column are bolted to connection, and the bottom of described preparative column is fixedly connected with by the chain clip with described bottom end cover.
2. a kind of multi-functional liquid phase according to claim 1 prepares dynamic axial compression column, it is characterized in that:
Be provided with sealing ring, distributor and filter plate in the described bottom end cover, described end cap bottom is provided with the liquid phase outlet spout, and described distributor is arranged on the top of described liquid phase outlet spout, is provided with filter plate on the described distributor.
3. a kind of multi-functional liquid phase according to claim 1 prepares dynamic axial compression column, it is characterized in that:
The column length of described transition mast is 30cm.
4. a kind of multi-functional liquid phase according to claim 1 prepares dynamic axial compression column, it is characterized in that:
The column length of described preparative column is 23cm.
5. a kind of multi-functional liquid phase according to claim 1 prepares dynamic axial compression column, it is characterized in that:
The inwall glossiness of described preparative column and described transition mast is less than 0.02 micron.
6. a kind of multi-functional liquid phase according to claim 1 prepares dynamic axial compression column, it is characterized in that:
The inwall glossiness of described preparative column and described transition mast equals 0.02 micron.
7. a kind of multi-functional liquid phase according to claim 1 prepares dynamic axial compression column, it is characterized in that:
Described transition mast column casing thickness is 0.8-1cm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220540691 CN202822869U (en) | 2012-10-22 | 2012-10-22 | Multifunctional liquid phase preparation dynamic axial compression column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220540691 CN202822869U (en) | 2012-10-22 | 2012-10-22 | Multifunctional liquid phase preparation dynamic axial compression column |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202822869U true CN202822869U (en) | 2013-03-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220540691 Expired - Fee Related CN202822869U (en) | 2012-10-22 | 2012-10-22 | Multifunctional liquid phase preparation dynamic axial compression column |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202822869U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104707360A (en) * | 2013-12-11 | 2015-06-17 | 江苏鑫润环保科技有限公司 | Static axial compression column assembling machine |
-
2012
- 2012-10-22 CN CN 201220540691 patent/CN202822869U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104707360A (en) * | 2013-12-11 | 2015-06-17 | 江苏鑫润环保科技有限公司 | Static axial compression column assembling machine |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130327 Termination date: 20201022 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |