CN202720230U - Portable high-resolution gold labeled detection instrument - Google Patents

Portable high-resolution gold labeled detection instrument Download PDF

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Publication number
CN202720230U
CN202720230U CN 201220303242 CN201220303242U CN202720230U CN 202720230 U CN202720230 U CN 202720230U CN 201220303242 CN201220303242 CN 201220303242 CN 201220303242 U CN201220303242 U CN 201220303242U CN 202720230 U CN202720230 U CN 202720230U
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gold
radio
portable
frequency
test strip
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CN 201220303242
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Chinese (zh)
Inventor
王宇晓
王宏强
雷勇智
马洪芳
余明
王春飞
张广
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TIANJIN PURUI INSTRUMENT CO Ltd
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TIANJIN PURUI INSTRUMENT CO Ltd
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Abstract

The utility model provides a portable high-resolution gold labeled detection instrument which is composed of a light path system, a circuit system and a gold labeled test paper card. Six AA batteries which are arranged in the detection instrument are used for supplying power, and the detection instrument can also be externally connected with a 9V direct current power source. A highlight light-emitting diode (LED) light source, a high-sensitivity 2048-pixel linear array charge coupled device (CCD) image sensor, and a 16-bit A/D converter are adopted by the detection instrument. The detection instrument can achieve 65536 resolution ratio, has functions of information detecting, radio frequency tag reading, signal processing, liquid-crystal display, an universal serial bus (USB) connector, bluetooth communication and the like, can be widely applied to hospital clinical detection and spot rapid detection, and is high in distinguished grade of the detected fluid (a sample) coloration condition, small in whole instrument size, safe and reliable in use, wide in detection range, small in size and portable.

Description

A kind of Portable High Resolution gold mark detector
Technical field
The present invention relates to a kind of Portable High Resolution gold mark detector.
Background technology
Gold mark detector be 20th century a novel speed growing up of the nineties survey testing instruments, use antigen and antibody specific rule and collaurum colour developing principle, the range estimation colloid gold test strip developed the color intuitively the result with the feminine gender of judging strip with positive.Developing rapidly along with electronic technology in recent years, with application of electronic technology in gold mark detecting instrument, the gold-label test strip quantitative tester has appearred, can carry out quantitative and semi-quantitative to sample detects, because easy and simple to handle, quick, reliable, price is lower, becomes one of technical way of fast detecting microbial pathogens and clinical quick diagnosis disease.The method of at present gold mark detector detection gold-marking test strip mainly is optical fiber scanning method and CCD imaging method.The optical fiber scanning method for the reflective light intensity of low concentration sample a little less than, affected the accuracy of measurement result, optical fiber scanning adopts mechanical scanner to drive Fibre Optical Sensor scanning, mechanical scanner complex structure, volume are larger.CCD imaging method non-scan device, speed is fast, and data read conveniently, small volume, but because resolution is lower, the quantitative measurment result is comparatively approaching between the sample of variable concentrations, instrument is restricted the differentiation grade of test solution concentration, has affected quantitative testing result accuracy.And because resolution is lower, cause the part sample approaching in the situation that develops the color and can not develop the color the qualitative conclusion that is easy to get and makes mistake.
Summary of the invention
The utility model is a kind of Portable High Resolution gold mark detector that provides for the above-mentioned technical matters that solves the existence of gold mark detector, whole instrument small volume, resolution is higher, have that information detects, the functions such as radio-frequency (RF) tag reads, signal processing, liquid crystal display, USB interface, bluetooth communication, built-in 6 joint AA powered battery also can external 9V direct supply, and are safe and reliable, sensing range is wide, miniature portable, can be widely used in hospital clinical and detect and field quick detection.
The utility model is taked following technical scheme for achieving the above object: a kind of Portable High Resolution gold mark detector is comprised of light path system, Circuits System, gold test strip card, the built-in 6 joint AA powered battery of detector, also can external 9V direct supply, whole detector volume is 210 * 110 * 70mm only, and schematic appearance is seen Fig. 1.
Light path system is by highlighted LED luminotron, catoptron, focus lamp (lens), ccd sensor, the gold test strip draw-in groove forms, it is characterized in that highlighted LED luminotron is positioned at gold test strip draw-in groove top one side and test paper draw-in groove plane is 20 degree angles, catoptron is higher than that the LED luminotron is positioned at directly over the gold test strip draw-in groove and be 45 degree angles with test paper draw-in groove plane, focus lamp, a coexist side and be positioned on the same level center line with catoptron of ccd sensor and LED luminotron, as shown in Figure 2, the LED luminotron, catoptron, focus lamp, ccd sensor is enclosed in the box, and only gold test strip draw-in groove place leaves perforate below closed enclosure.
Circuits System is comprised of radio-frequency (RF) tag read-write equipment, A/D converter, DSP, microcontroller, bluetooth communication module, USB interface, liquid crystal display, input key etc.; Wherein the radio-frequency (RF) tag read-write equipment is comprised of high-frequency model (transmitter and receiver) and antenna (pickup coil); Carry out radio communication by the radio-frequency (RF) tag in antenna and the gold test strip card, can realize reading or write operation test paper classification and internal storage data; The utility model instrument is provided with USB interface, can be connected with computing machine easily, reads the data of preserving in the fuselage storer; Instrument is provided with bluetooth communication module, can carry out the data transmission with host computer easily, and can with miniature blue teeth wireless printer communication to print measurement result.Liquid crystal display is 3.5 cun 320*240, cooperates the input film key, can carry out easily the man-machine interface operation.
The gold test strip card is comprised of colloidal gold immunochromatographimethod strip and radio-frequency (RF) tag and is encapsulated within the plastic casing, the colloidal gold immunochromatographimethod strip is positioned at top, a sample application zone is arranged on the strip, a colour developing district, there is C in the colour developing district, two colour bands of T, untapped test strips colour developing district background is white, during use, splash into 1 testing liquid to sample application zone, after the regular hour, observe the colour developing situation in colour developing district, article two, colour band appears as the positive simultaneously, and it is negative the C colour band only to occur, and the C colour band does not appear as error-detecting, different type of detection, the colloidal gold immunochromatographimethod strip is different; Radio-frequency (RF) tag is positioned at colloidal gold immunochromatographimethod strip below, and by the passive electronic label that coupling original paper (coil, microstrip antenna etc.) and microchip form, microchip has the information such as test card type, the date of production, numbering, as shown in Figure 3.
The utility model example is selected highlighted led light source, high sensitivity 2048 pixel Linear Array CCD Image Sensors, 16 A/D converters, resolution 65536, be that the greyscale color of strip chromogenic line is illustrated in 0~65535 the gray-scale value scope, the differentiation grade of identification test solution (sample) colour developing situation is higher.
The utility model main task is, obtain the detection data of line array CCD, test paper classification according to identification is processed these data, the identification trough, and the ratio of calculating trough amplitude, the ccd data form can be described with a curve, and as shown in Figure 4, two troughs represent the detected value of C and two colour bands of T.
The utility model is because image-forming block resolution and the sensitivity adopted are higher, for utilizing data redundancy, the special design according to the sample classification Lookup protocol parameter of obtaining at microcontroller software reaches the manually function of parameters, the part sample is approached in the situation that develops the color and can not develop the color, by adjusting characteristic parameter, instrument can be made correct qualitative conclusion, thus solved the part sample because of can not develop the color can't be accurately problem qualitatively.
Complete machine principle of work block diagram as shown in Figure 5, during instrument work, at first start the radio-frequency (RF) tag read-write equipment, read the test paper classification, reach microcontroller, microcontroller is adjusted led light source according to the test paper classification, the gold test strip card colour developing that led light source shines in the gold test strip draw-in groove is distinguished, reflected light through mirror reflects to focus lamp (lens), light line focus mirror (lens) imports ccd sensor into, ccd sensor is converted to the simulating signal that voltage magnitude does not wait with light signal, the A/D converter of simulating signal on control circuit board is converted to digital signal and sends into DSP, and DSP detects data to the CCD that obtains and carries out the data processing according to radio-frequency (RF) tag test paper type, the ccd data form is described with a curve, the ratio of calculated curve trough amplitude, as shown in Figure 4, two troughs represent the detected value of C and two colour bands of T.The data that microcontroller will be measured, analyze and result are in the liquid crystal screen display, displaying contents mainly contains detection time, detection data (ratio of C and T band), judged result (negative or positive), test card classification etc., simultaneously and in the radio-frequency (RF) tag of the result store that will measure, analyze to storer and the gold test strip card, so that gathering information is watched at any time.
Description of drawings
Accompanying drawing 1 the utility model schematic appearance
Accompanying drawing 2 light path system structure and fundamental diagrams
Accompanying drawing 3 gold test strip card structure figure
Accompanying drawing 4CCD detects data and curves
Accompanying drawing 5 fundamental diagrams
Number in the figure: 1 highlighted LED luminotron, 2 gold test strip draw-in grooves, 3 catoptrons, 4 focus lamps (lens), 5CCD sensor, 6 radio-frequency (RF) tag, 7 colloidal gold immunochromatographimethod strips, 8 sample application zone, 9 colour developing districts, 10 colour developing district D bar colour bands, 11 colour developing district C bar colour bands
Embodiment
A kind of Portable High Resolution gold mark detector is comprised of light path system, Circuits System, gold test strip card, and the built-in 6 joint AA powered battery of detector also can external 9V direct supply, and whole detector volume is 210 * 110 * 70mm only, and schematic appearance is seen Fig. 1.Light path system is by highlighted LED luminotron, catoptron, focus lamp (lens), ccd sensor, the gold test strip draw-in groove forms, it is characterized in that highlighted LED luminotron is positioned at gold test strip draw-in groove top one side and test paper draw-in groove plane is 20 degree angles, catoptron is higher than that the LED luminotron is positioned at directly over the gold test strip draw-in groove and be 45 degree angles with test paper draw-in groove plane, focus lamp, a coexist side and be positioned on the same level center line with catoptron of ccd sensor and LED luminotron, as shown in Figure 2, the LED luminotron, catoptron, focus lamp, ccd sensor is enclosed in the box, and only gold test strip draw-in groove place leaves perforate below closed enclosure.Circuits System is comprised of radio-frequency (RF) tag read-write equipment, A/D converter, DSP, microcontroller, bluetooth communication module, USB interface, liquid crystal display etc.; Wherein the radio-frequency (RF) tag read-write equipment is comprised of high-frequency model (transmitter and receiver) and antenna (pickup coil); Carry out radio communication by the radio-frequency (RF) tag in antenna and the gold test strip card, can realize reading or write operation test paper classification and internal storage data; The utility model instrument is provided with USB interface, can be connected with computing machine easily, reads the data of preserving in the fuselage storer; Instrument is provided with bluetooth communication module, can carry out the data transmission with host computer easily, and can with miniature blue teeth wireless printer communication to print measurement result.Liquid crystal display is 3.5 cun 320*240, cooperates the input film key, can carry out easily the man-machine interface operation.The gold test strip card is comprised of colloidal gold immunochromatographimethod strip and radio-frequency (RF) tag and is encapsulated within the plastic casing, the colloidal gold immunochromatographimethod strip is positioned at top, a sample application zone is arranged on the strip, a colour developing district, there is C in the colour developing district, two colour bands of T, untapped test strips colour developing district background is white, during use, splash into 1 testing liquid to sample application zone, after the regular hour, observe the colour developing situation in colour developing district, article two, colour band appears as the positive simultaneously, and it is negative the C colour band only to occur, and the C colour band does not appear as error-detecting, different type of detection, the colloidal gold immunochromatographimethod strip is different; Radio-frequency (RF) tag is positioned at colloidal gold immunochromatographimethod strip below, and by the passive electronic label that coupling original paper (coil, microstrip antenna etc.) and microchip form, microchip has the information such as test card type, the date of production, numbering, as shown in Figure 3.
The utility model example is selected highlighted led light source, high sensitivity 2048 pixel Linear Array CCD Image Sensors, 16 A/D converters, resolution 65536, DSP obtains the detection data of line array CCD, these data is processed the identification trough according to the test paper classification of identification, and the ratio of calculating trough amplitude, the ccd data form can be described with a curve, and as shown in Figure 4, two troughs represent the detected value of C and two colour bands of T.
The utility model is because image-forming block resolution and the sensitivity adopted are higher, the special design according to the sample classification Lookup protocol parameter of obtaining at microcontroller software reaches the manually function of parameters, the part sample is approached in the situation that develops the color and can not develop the color, by adjusting characteristic parameter, instrument can be made correct qualitative conclusion.
Complete machine principle of work block diagram as shown in Figure 5, during instrument work, at first start the radio-frequency (RF) tag read-write equipment, read the test paper classification, reach microcontroller, microcontroller is adjusted led light source according to the test paper classification, the gold test strip card colour developing that led light source shines in the gold test strip draw-in groove is distinguished, reflected light through mirror reflects to focus lamp (lens), light line focus mirror (lens) imports ccd sensor into, ccd sensor is converted to the simulating signal that voltage magnitude does not wait with light signal, the A/D converter of simulating signal on control circuit board is converted to digital signal and sends into DSP, and DSP detects data to the CCD that obtains and carries out the data processing according to radio-frequency (RF) tag test paper type, the ccd data form is described with a curve, the ratio of calculated curve trough amplitude, as shown in Figure 4, two troughs represent the detected value of C and two colour bands of T.With the data measuring, analyze and result in the liquid crystal screen display, displaying contents mainly contains detection time, detection data (ratio of C and T band), judged result (negative or positive), test card classification etc., simultaneously and in the radio-frequency (RF) tag of the result store that will measure, analyze to body storer and the gold test strip card, so that gathering information is watched at any time.
Above content can not assert that implementation of the present invention is confined to these explanations.For the general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace, all should be considered as belonging to protection scope of the present invention.

Claims (4)

1. a Portable High Resolution gold is marked detector, it is characterized in that gold mark detector is comprised of light path system, Circuits System, gold test strip card, the built-in 6 joint AA powered battery of detector also can external 9V direct supply, and whole detector volume only is 210mm * 110mm * 70mm.
2. a kind of Portable High Resolution gold according to claim 1 is marked detector, it is characterized in that light path system is by highlighted LED luminotron, catoptron, focus lamp, ccd sensor, the gold test strip draw-in groove forms, highlighted LED luminotron is positioned at gold test strip draw-in groove top one side and test paper draw-in groove plane is 20 degree angles, catoptron is higher than that the LED luminotron is positioned at directly over the gold test strip draw-in groove and be 45 degree angles with test paper draw-in groove plane, focus lamp, a coexist side and be positioned on the same level center line with catoptron of ccd sensor and LED luminotron, the LED luminotron, catoptron, focus lamp, ccd sensor is enclosed in the box, and only gold test strip draw-in groove place leaves perforate below closed enclosure.
3. a kind of Portable High Resolution gold mark detector according to claim 1 is characterized in that Circuits System is comprised of radio-frequency (RF) tag read-write equipment, A/D converter, DSP, microcontroller, bluetooth communication module, USB interface, liquid crystal display; Wherein the radio-frequency (RF) tag read-write equipment is comprised of high-frequency model and antenna; Carry out radio communication by the radio-frequency (RF) tag in antenna and the gold test strip card, can realize reading or write operation test paper classification and internal storage data; The utility model instrument is provided with USB interface, can be connected with computing machine easily, reads the data of preserving in the fuselage storer; Instrument is provided with bluetooth communication module, can carry out the data transmission with host computer easily, and can with miniature blue teeth wireless printer communication to print measurement result; Liquid crystal display is 3.5 cun 320*240, cooperates the input film key, can carry out easily the man-machine interface operation.
4. a kind of Portable High Resolution gold according to claim 1 is marked detector, it is characterized in that the gold test strip card is comprised of colloidal gold immunochromatographimethod strip and radio-frequency (RF) tag and is encapsulated within the plastic casing, the colloidal gold immunochromatographimethod strip is positioned at top, a sample application zone is arranged on the strip, a colour developing district, there are two colour bands of C, T in the colour developing district; Radio-frequency (RF) tag is positioned at colloidal gold immunochromatographimethod strip below, the passive electronic label that is comprised of coupling original paper and microchip.
CN 201220303242 2012-06-27 2012-06-27 Portable high-resolution gold labeled detection instrument Active CN202720230U (en)

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Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103197060A (en) * 2013-03-24 2013-07-10 湖南远泰生物技术有限公司 Autonomous recognition, positioning and quantitative detecting system and detecting method for colloidal gold immunochromatographic boxes
CN103226145A (en) * 2013-03-24 2013-07-31 湖南远泰生物技术有限公司 Autonomous identification positioning and quantitative detection system of colloidal gold immunochromatography box
CN103245780A (en) * 2013-04-27 2013-08-14 北京福乐云检测科技有限公司 Colloidal gold anti-counterfeiting tracing cloud platform
CN103245782A (en) * 2013-04-27 2013-08-14 北京福乐云检测科技有限公司 Colloidal gold method online detector
CN103259855A (en) * 2013-04-27 2013-08-21 北京福乐云检测科技有限公司 Cloud platform of infectious disease and chronic disease detecting and monitoring pre-warning system
CN103499699A (en) * 2013-09-27 2014-01-08 南昌大学 Fluorescent microsphere immunochromatographic assay quantitative detector by combination of internet-of-things data transmission system
CN103698323A (en) * 2013-08-24 2014-04-02 管义东 Colloidal gold immunochromatographic test paper detection system
CN103776998A (en) * 2014-02-28 2014-05-07 常州思康立生物科技有限公司 Portable immune-chromatography analysis meter
CN104123516A (en) * 2013-04-23 2014-10-29 苏州慧康电子信息科技有限公司 Gold label card detection method and reader based cloud computation network platform
CN104122388A (en) * 2013-04-23 2014-10-29 苏州慧康电子信息科技有限公司 Batch reader and test method for gold-label detection card
WO2014176753A1 (en) * 2013-04-30 2014-11-06 成都领御生物技术有限公司 Quantum-dot immunochromatographic test strip detection system and use thereof
CN104764879A (en) * 2015-04-13 2015-07-08 大连理工大学 Linear-array CCD quantitative detection device of immnochromatography reaction result
CN104820091A (en) * 2015-05-21 2015-08-05 厦门大学 Immunochromatographic test strip quantitative detection condition monitoring system and method based on wireless sensor network
CN104931417A (en) * 2015-06-09 2015-09-23 上海仪电物理光学仪器有限公司 High-precision gold-labeled strip reader
CN105911277A (en) * 2016-04-25 2016-08-31 成都盛泰尔生物医药科技有限公司 Animal epidemic disease antibody virus colloidal gold quantitative detection system and preparation method thereof
CN106290321A (en) * 2016-11-14 2017-01-04 无锡艾科瑞思产品设计与研究有限公司 A kind of health-law performing intelligent terminal with fast-food detection function
CN109738622A (en) * 2018-12-29 2019-05-10 北京化工大学 Lateral flow paper slip device for fast detecting based on micro-fluidic chip

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103197060A (en) * 2013-03-24 2013-07-10 湖南远泰生物技术有限公司 Autonomous recognition, positioning and quantitative detecting system and detecting method for colloidal gold immunochromatographic boxes
CN103226145A (en) * 2013-03-24 2013-07-31 湖南远泰生物技术有限公司 Autonomous identification positioning and quantitative detection system of colloidal gold immunochromatography box
CN104123516A (en) * 2013-04-23 2014-10-29 苏州慧康电子信息科技有限公司 Gold label card detection method and reader based cloud computation network platform
CN104122388A (en) * 2013-04-23 2014-10-29 苏州慧康电子信息科技有限公司 Batch reader and test method for gold-label detection card
CN103245782A (en) * 2013-04-27 2013-08-14 北京福乐云检测科技有限公司 Colloidal gold method online detector
CN103259855A (en) * 2013-04-27 2013-08-21 北京福乐云检测科技有限公司 Cloud platform of infectious disease and chronic disease detecting and monitoring pre-warning system
CN103259855B (en) * 2013-04-27 2016-03-30 北京福乐云检测科技有限公司 Infectious disease, slow sick detection and supervision early warning system cloud platform
CN103245782B (en) * 2013-04-27 2015-10-14 北京福乐云检测科技有限公司 Colloidal gold method on-line detector
CN103245780A (en) * 2013-04-27 2013-08-14 北京福乐云检测科技有限公司 Colloidal gold anti-counterfeiting tracing cloud platform
CN105393108A (en) * 2013-04-30 2016-03-09 成都领御生物技术有限公司 Quantum-dot immunochromatographic test strip detection system and use thereof
WO2014176753A1 (en) * 2013-04-30 2014-11-06 成都领御生物技术有限公司 Quantum-dot immunochromatographic test strip detection system and use thereof
CN103698323A (en) * 2013-08-24 2014-04-02 管义东 Colloidal gold immunochromatographic test paper detection system
CN103499699A (en) * 2013-09-27 2014-01-08 南昌大学 Fluorescent microsphere immunochromatographic assay quantitative detector by combination of internet-of-things data transmission system
CN103776998A (en) * 2014-02-28 2014-05-07 常州思康立生物科技有限公司 Portable immune-chromatography analysis meter
CN103776998B (en) * 2014-02-28 2015-06-10 常州思康立生物科技有限公司 Portable immune-chromatography analysis meter
CN104764879A (en) * 2015-04-13 2015-07-08 大连理工大学 Linear-array CCD quantitative detection device of immnochromatography reaction result
CN104820091A (en) * 2015-05-21 2015-08-05 厦门大学 Immunochromatographic test strip quantitative detection condition monitoring system and method based on wireless sensor network
CN104931417A (en) * 2015-06-09 2015-09-23 上海仪电物理光学仪器有限公司 High-precision gold-labeled strip reader
CN105911277A (en) * 2016-04-25 2016-08-31 成都盛泰尔生物医药科技有限公司 Animal epidemic disease antibody virus colloidal gold quantitative detection system and preparation method thereof
CN106290321A (en) * 2016-11-14 2017-01-04 无锡艾科瑞思产品设计与研究有限公司 A kind of health-law performing intelligent terminal with fast-food detection function
CN109738622A (en) * 2018-12-29 2019-05-10 北京化工大学 Lateral flow paper slip device for fast detecting based on micro-fluidic chip
CN109738622B (en) * 2018-12-29 2020-12-11 北京化工大学 Lateral flow paper strip rapid detection device based on micro-fluidic chip

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