CN202681903U - Peeping optical coherence tomography (OCT) imaging device - Google Patents
Peeping optical coherence tomography (OCT) imaging device Download PDFInfo
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- CN202681903U CN202681903U CN 201220070781 CN201220070781U CN202681903U CN 202681903 U CN202681903 U CN 202681903U CN 201220070781 CN201220070781 CN 201220070781 CN 201220070781 U CN201220070781 U CN 201220070781U CN 202681903 U CN202681903 U CN 202681903U
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Abstract
The utility model discloses a peeping optical coherence tomography (OCT) imaging device which comprises a frequency sweep light source, a light circulator, a peeping probe, a difference detector and a computing control unit. The port a of the light circulator is connected with the frequency sweep light source through an optical fiber. The peeping probe comprises a lens, a two-dimension scanning micromirror and a probe glass window, and light focused by the lens is reflected by the two-dimension scanning micromirror and irradiates on a sample through the probe glass window. The incidence face of the lens is connected with the port b of the light circulator through the optical fiber, and an 8 degree obliquity is formed between the incidence face of the lens and the vertical section of the connection end face of the optical fiber. The input end of the difference detector is connected with the port c of the light circulator through the light fiber. The input end of the computing control unit is connected with the output end of the difference detector. Furthermore, the two-dimension scanning micromirror is a micro electro mechanical system (MEMS) two-dimension scanning micromirror. Compared with the prior art, the peeping OCT imaging device has the advantages of being simple in structure and free of an optical path difference compensation system, and does not need optical path matching.
Description
Technical field
This utility model relates to a kind of endoscopic OCT imaging device, belongs to optical coherent chromatographic imaging (Optical Coherence Tomography is called for short OCT) technical field.
Background technology
Medical science endoscope is noinvasive or the minimally invasive medical instrument of medically commonly using at present, can be by the lesion tissue of its direct observation human internal organs.The internal surface can only be observed by traditional endoscope, the introducing of ultrasonic technique then so that endoscope can observe the tissue morphology of organ tomography, but since its resolution lower, often be difficult to reach the required level of resolution of Accurate Diagnosis.
The combination of Optical Coherence Tomography Imaging Technology and endoscope becomes possibility so that internal's tomography is carried out the high-resolution observation.Clinical experiment shows that the high-resolution that OCT provides can be used for the detection of various diseases noinvasive, as: ophthalmology, department of dermatologry, oral cavity, Pneumology Department, Digestive System Department etc.Also can measure in conjunction with Doppler technology the function informations such as velocity of blood flow.The organ early-stage cancer detects in human body, and has unrivaled advantage on the tumor resection.
In existing endoscopic OCT system, spy upon an Optic transmission fiber in generally inciting somebody to action and place on the sample arm of interference structure.Because the inner-cavity structure very irregular of intracorporeal organ, the optical fiber that enters in it inevitably bends and twisted phenomena, causes the variation of optic fibre transmision light beam polarization state, and the dispersive influence that causes thus, thereby image quality is descended.Therefore, must in reference arm, carry out exact matching to above-mentioned factor, cause the formation of system and the adjusting complex that becomes.And each replacing of probe all must be carried out the complex operations such as light path coupling, dispersion compensation and polarization state adjusting of large stroke.
For addressing the above problem, one piece of Chinese invention patent (application number is 200710070102.0, and the applying date is 2007-07-20, authorizes day to be 2009-04-22) discloses a kind of " rigid pipe type common-path type endoscopic OCT parallel imaging method and system ".This system as reference light, and consists of an altogether sensing interferometer on road from the flashlight of sample with the end face reflection light of Green rod lens, and the optical path difference between reference light and the flashlight is compensated by another common path interference instrument.This invention is owing to adopted common path interference structure, image quality to be subjected to hardly environment (such as variations in temperature, resonator device dispersion etc.) impact; And need not that system is carried out complexity regulates.
But still there is following defective in above-mentioned " rigid pipe type common-path type endoscopic OCT parallel imaging method and system ":
1, adopt wideband light source in this scheme, its coherence length only has several micron, so the optical path difference between reference light and the flashlight need to compensate by another common path interference instrument, has improved the structure complexity of system, has increased cost; And when operation, need to carry out the light path coupling.
2, in this scheme, reflecting mirror drives reflecting mirror by the step motor drive electronic control translation stage and moves axially, and realizes scanning; Complex structure is difficult to realize microminiaturized.
The utility model content
Technical problem to be solved in the utility model is to overcome the existing deficiency of prior art, and a kind of endoscopic OCT imaging device is provided, and this apparatus structure is simple, does not need the optical path difference bucking-out system, does not also need to carry out the light path coupling.
This utility model specifically solves the problems of the technologies described above by the following technical solutions.
A kind of endoscopic OCT imaging device comprises:
Swept light source;
Optical circulator, its a port is connected with described swept light source by optical fiber;
In spy upon head, comprise lens, two-dimensional scan micro mirror and probe windowpane, the light that lens converge exposes to sample through the reflection of two-dimensional scan micro mirror and by the probe windowpane; The plane of incidence of described lens is connected with the b port of described optical circulator by optical fiber, is 8 ° of inclination angles between the connecting end surface of the lens plane of incidence and this optical fiber and the vertical section of this optical fiber;
Differential detector, its input is connected with the c port of described optical circulator by optical fiber;
Calculation control unit, its input is connected with the outfan of described differential detector.
Further, this utility model can utilize the reflected light of the probe upper and lower surface of windowpane or lens exit facet as reference light, only need the catoptrical optical path difference of reference light and sample to get final product less than the coherence length of light source, that is one of following three kinds of optical path differences are less than the coherence length of described swept light source:
Light arrives sample surfaces and is reflected back the light and the catoptrical optical path difference of probe windowpane upper surface of probe windowpane upper surface through sample surfaces;
Light arrives sample surfaces and is reflected back the light and the catoptrical optical path difference of probe windowpane lower surface of probe windowpane lower surface through sample surfaces;
Light arrives light and the catoptrical optical path difference of lens exit facet that sample surfaces is reflected back the lens exit facet.
Further, described two-dimensional scan micro mirror is MEMS two-dimensional scan micro mirror, comprises micro mirror and is used for driving the MEMS driving device that described micro mirror carries out two dimensional motion, and the control end of MEMS driving device is connected with the outfan of described calculation control unit.
A kind of endoscopic OCT formation method adopts as mentioned above endoscopic OCT imaging device; Specifically may further comprise the steps:
Step 1, swept light source produce the frequency sweep incident illumination, successively through optical circulator and in spy upon head and be incident upon sample surfaces;
One of the light of step 2, sample surfaces reflection and following three kinds of reflected light produce interferes:
The reflected light of probe windowpane upper surface;
The reflected light of probe windowpane lower surface;
The reflected light of lens exit facet;
Compared to existing technology, the utlity model has following beneficial effect:
1, this utility model does not need the optical path difference bucking-out system, and structure complexity is low; The wideband light source coherence length only has several microns, and the swept light source coherence length that this utility model uses reaches tens millimeters, as long as the optical path difference of two relevant light beams just can produce interference less than the coherence length of laser, the optical length of tens millimeters is a lot of easily than several microns optical path difference, so do not need the optical path difference compensation arrangement.
2, this utility model adopts MEMS micro mirror Scan Architecture, and driving device is small, and required driving voltage has structure mini, uses safe characteristics less than 5 volts; Probe diameter can be as small as 2 several millimeters, thereby easilier enters various organs and carry out imaging.
3, capacity usage ratio of the present utility model is high, has only used an optical circulator, and the energy that itself and MEMS micro mirror consume is very little.
Description of drawings
Fig. 1 is the structural representation of this utility model endoscopic OCT imaging device;
Fig. 2 is the relevant principle schematic of the common light path of this utility model endoscopic OCT imaging device;
Fig. 3 spies upon the header structure sketch map in of the present utility model;
Fig. 4 is the scanning sketch map of MEMS two-dimensional scan micro mirror;
Each label implication among the figure: 1, swept light source, 2, optical circulator, 3, image transmission optical fibre, 4, Green lens, 5, MEMS
The two-dimensional scan micro mirror, 6, sample, 7, differential detector, 8, Green lens outgoing end face, 9, probe sleeve,
10, two surfaces about the probe windowpane.
The specific embodiment
Below in conjunction with accompanying drawing the technical solution of the utility model is elaborated:
Thinking of the present utility model is to utilize the great coherence length of swept light source, to existing common path type endoscopic OCT
System improves, thus light requirement path difference compensation arrangement not, simplied system structure; And further adopt MEMS two-dimensional scan micro mirror to realize the microminiaturization of probe.Swept light source refers to the time dependent light source of output wavelength, and its coherence length reaches tens millimeters, and the frequency sweep frequency reaches 50KHz.Endoscopic OCT imaging device of the present utility model as shown in Figure 1, comprising: swept light source 1, optical circulator 2, image transmission optical fibre 3, differential detector 7, calculation control unit (not shown) are spied upon head in reaching; Spy upon head wherein as shown in the figure, comprise Green lens 4, MEMS two-dimensional scan micro mirror 5, probe sleeve 9 and probe windowpane.Swept light source 1 is connected with a port of optical circulator 2 by optical fiber, and the b port of optical circulator 2 is connected with Green lens 4 by image transmission optical fibre 3.When using 4 pairs of image transmission optical fibre 3 output beams of Green lens to assemble, Green lens incident end face reflected light is formed into the picture interfering signal in the detector image planes, must make it deflect away from image planes, be 8 ° of inclination angles so need make between the vertical section of the connecting end surface of the plane of incidence of Green lens 4 and image transmission optical fibre 3 and image transmission optical fibre 3.
The light that swept light source 1 is sent enters the port a of optical circulator 2, and by the port b outgoing of optical circulator 2, by image transmission optical fibre 3, when transferring to the outgoing end face of Green lens 4, light beam is divided into back reflected laser and transillumination again.Transillumination is focused on by Green lens 4 and reflexes on the sample 6 by MEMS two-dimensional scan micro mirror 5.Adopt in the side direction type in this specific embodiment and spy upon head, its structure as shown in Figure 3, namely the light through MEMS two-dimensional scan micro mirror 5 reflection is radiated on the sample 6 through the probe windowpane (the 10 upper and lower surfaces for the probe windowpane among the figure) that is installed in probe sleeve 9 sides.By sample 6 reflection or backward scattered light, and the light of the upper and lower surface reflection of probe glass window 10, or by the light of outgoing end face 8 reflections of Green lens 4, after the formation interference light turns back to optical circulator 2 along former road, be transferred to differential detector 7 by port c again.
In this specific embodiment, the optical fiber that is connected that optical circulator 2 and swept light source 1, differential detector 7, Green lens are 4 all adopts single-mode fiber.
The MEMS two-dimensional scan micro mirror that this utility model adopts is prior art, and it is that MEMS (Micro-electro-mechanical systems is called for short MEMS) is used the typical case of optical field.The MEMS micro mirror generally includes micro mirror and is used for driving the MEMS driving device that described micro mirror carries out two dimensional motion, and its principle is three kinds of type of drive utilizing in the MEMS: electrostatic force, electromagnetic force, electric heating drive micromirror movements.Therefore can be divided into electrostatic MEMS two-dimensional scan micro mirror, electromagnetic type MEMS two-dimensional scan micro mirror and electric heating MEMS two-dimensional scan micro mirror.Adopt electric heating MEMS two-dimensional scan micro mirror in this specific embodiment, its scanning theory as shown in Figure 4, the angular deflection that the MEMS micro mirror produces X, Y-direction because the energising of cantilever beam heating produces deformation realizes the scanning of X, Y-direction.
In this specific embodiment, calculation control unit comprises computer and the capture card that is connected with computer respectively, MEMS drive circuit; Capture card is connected with the outfan of differential detector, the interference signal that detects in order to gather differential detector, and interference signal transferred to computer; The MEMS drive circuit is connected with the driving device of MEMS two-dimensional scan micro mirror, produces driving voltage in order to the control signal according to computer, drives micromirror movements; Computer carries out date processing and demonstration to the interference signal that receives, and the control signal of output MEMS drive circuit.
Relevant principle of the present utility model as shown in Figure 2, the back reflected laser of Green lens 4 outgoing end faces 8 is as reference light R, or on the probe windowpane or the reflected light of lower surface 10 as reference light R, its light path is LR, the transillumination of Green lens 4 outgoing end faces 8 reflexes to through MEMS and is reflected back Green lens 4 outgoing end faces 8 or probe windowpane upper and lower surperficial 10 on the sample 6 again, as sample reflected light S, both optical path differences are Δ L=2(LR-LS), it is that Δ L is less than the coherence length of light source 1 that reference light R and sample reflected light S form the condition of interfering.
Adopt said apparatus to carry out the endoscopic OCT imaging, according to following steps:
Step 1, swept light source 1 produces the frequency sweep incident illumination, successively through optical circulator 2 and in spy upon head and be incident upon sample 6 surfaces;
One of the light of step 2, sample 6 surface reflections and following three kinds of reflected light produce interferes:
The reflected light of probe windowpane upper surface;
The reflected light of probe windowpane lower surface;
The reflected light of Green lens 4 exit facets;
As shown in Figure 2, the optical path difference of three kinds of interference is respectively: 2(△ L+L1), 2(L1-L2), 2(L1-L3);
Claims (6)
1. an endoscopic OCT imaging device is characterized in that, comprising:
Swept light source;
Optical circulator, its a port is connected with described swept light source by optical fiber;
In spy upon head, comprise lens, two-dimensional scan micro mirror and probe windowpane, the light that lens converge exposes to sample through the reflection of two-dimensional scan micro mirror and by the probe windowpane; The plane of incidence of described lens is connected with the b port of described optical circulator by optical fiber, is 8 ° of inclination angles between the connecting end surface of the lens plane of incidence and this optical fiber and the vertical section of this optical fiber;
Differential detector, its input is connected with the c port of described optical circulator by optical fiber;
Calculation control unit, its input is connected with the outfan of described differential detector.
2. endoscopic OCT imaging device as claimed in claim 1 is characterized in that, one of following three kinds of optical path differences are less than the coherence length of described swept light source:
Light arrives sample surfaces and is reflected back the light and the catoptrical optical path difference of probe windowpane upper surface of probe windowpane upper surface through sample surfaces;
Light arrives sample surfaces and is reflected back the light and the catoptrical optical path difference of probe windowpane lower surface of probe windowpane lower surface through sample surfaces;
Light arrives light and the catoptrical optical path difference of lens exit facet that sample surfaces is reflected back the lens exit facet.
3. endoscopic OCT imaging device as claimed in claim 2, it is characterized in that, described two-dimensional scan micro mirror is MEMS two-dimensional scan micro mirror, comprise micro mirror and be used for driving the MEMS driving device that described micro mirror carries out two dimensional motion that the control end of MEMS driving device is connected with the outfan of described calculation control unit.
4. endoscopic OCT imaging device as claimed in claim 3 is characterized in that described MEMS two-dimensional scan micro mirror is electrostatic MEMS two-dimensional scan micro mirror, electromagnetic type MEMS two-dimensional scan micro mirror or electric heating MEMS two-dimensional scan micro mirror.
5. such as claim 1-4 endoscopic OCT imaging device as described in each, it is characterized in that described lens are Green lens.
6. such as claim 1-4 endoscopic OCT imaging device as described in each, it is characterized in that described optical fiber is single-mode fiber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220070781 CN202681903U (en) | 2012-02-29 | 2012-02-29 | Peeping optical coherence tomography (OCT) imaging device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220070781 CN202681903U (en) | 2012-02-29 | 2012-02-29 | Peeping optical coherence tomography (OCT) imaging device |
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| CN202681903U true CN202681903U (en) | 2013-01-23 |
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| CN 201220070781 Withdrawn - After Issue CN202681903U (en) | 2012-02-29 | 2012-02-29 | Peeping optical coherence tomography (OCT) imaging device |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102578993A (en) * | 2012-02-29 | 2012-07-18 | 无锡微奥科技有限公司 | Endoscopic OCT (optical coherence tomography) imaging apparatus and endoscopic OCT imaging method |
| CN104095604A (en) * | 2013-12-24 | 2014-10-15 | 北京华科创智健康科技股份有限公司 | Endoscopic OCT (optical coherence tomography) probe with operating distance being capable of automatically and continuously adjusted |
| CN104991338A (en) * | 2015-07-31 | 2015-10-21 | 苏州微清医疗器械有限公司 | Confocal fundus scanning microscope |
| WO2019233425A1 (en) * | 2018-06-05 | 2019-12-12 | Zhang Hongming | Confocal microscopy system employing optical fiber coupler |
-
2012
- 2012-02-29 CN CN 201220070781 patent/CN202681903U/en not_active Withdrawn - After Issue
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102578993A (en) * | 2012-02-29 | 2012-07-18 | 无锡微奥科技有限公司 | Endoscopic OCT (optical coherence tomography) imaging apparatus and endoscopic OCT imaging method |
| CN102578993B (en) * | 2012-02-29 | 2014-05-28 | 无锡微奥科技有限公司 | Endoscopic OCT (optical coherence tomography) imaging apparatus and endoscopic OCT imaging method |
| CN104095604A (en) * | 2013-12-24 | 2014-10-15 | 北京华科创智健康科技股份有限公司 | Endoscopic OCT (optical coherence tomography) probe with operating distance being capable of automatically and continuously adjusted |
| CN104095604B (en) * | 2013-12-24 | 2015-12-02 | 北京华科创智健康科技股份有限公司 | The endoscopic OCT probe that operating distance Automatic continuous regulates |
| CN104991338A (en) * | 2015-07-31 | 2015-10-21 | 苏州微清医疗器械有限公司 | Confocal fundus scanning microscope |
| WO2019233425A1 (en) * | 2018-06-05 | 2019-12-12 | Zhang Hongming | Confocal microscopy system employing optical fiber coupler |
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Legal Events
| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20130123 Effective date of abandoning: 20140528 |
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| RGAV | Abandon patent right to avoid regrant |