CN202538180U - Therapeutic apparatus capable of stimulating cells with cardiovascular disease - Google Patents

Abstract

The utility model discloses a therapeutic apparatus capable of stimulating cells with cardiovascular disease. The therapeutic apparatus is characterized by comprising a shell and an electromagnetic wave generator, wherein the electromagnetic wave generator is arranged in the shell, can be used for applying electromagnetic waves to a human body and comprises a central processing unit, a digital to analog converter, a multiplexer and a current inductor; the central processing unit outputs a pulsewidth control waveform which is input into the digital to analog converter; the digital to analog converter generates a voltage waveform of time variation of a voltage station; and the multiplexer is used for converting the voltage waveform into a current waveform. The therapeutic apparatus has the advantages that customized electromagnetic waves are adopted and can be used for achieving a better therapeutic effect on a specific disease (the cardiovascular disease) and especially achieving a favorable therapeutic effect on hypertension and the heart disease; and the therapeutic effect is verified by a number of contratests.

Description

Cardiovascular disease cell excitation therapeutic instrument

Technical field

This utility model relates to treatment apparatus, particularly a kind of instrument of treating cardiovascular disease through electromagnetic radiation excitation cell.

Background technology

By enriching the blood circulation that vascular tissue constitutes is one of organ maximum in the human body.People are with the system of electromagnetic radiation shower whole human body, to attempt that human body is reached useful curative effect, to remember to be similar to the useful curative effect of conventional needle base therapy.

For example, application number is that 200810010145.4 Chinese utility model patent discloses a kind of high-energy biological field therapeutic equipment, is provided with power circuit; The output and the sampling amplification circuit of power circuit join; The output and the pulse generating circuit of sampling amplification circuit join, and the output and the power amplification circuit of impulse circuit join, and the output of power amplification circuit is leaded up to voltage regulator circuit and sampling amplification circuit and joined; One the tunnel joins with indicating circuit, and the outfan of indicating circuit is provided with electrode A, B.The electromagnetic wave that the voltage of being exported is adjusted between 35～220V can be got through collaterals of human fast; Activating blood circulation to dissipate blood stasis, expelling wind and cold, adjustment viscera equilibrium between yin and yang makes the potential difference between the human body cell obtain adjustment; Change the ordering of cellular elements structure, become unordered into orderly; Regulate human endocrine, make the human acid-base balance; Blood viscosity lowering, vessel softening improve cerebral blood supply, improve human body immunity and self-healing ability, make human body reach optimum state.

Application number is that 200620031025.9 Chinese utility model patent provides a kind of broadband electromagnetical wave spectrum health protection therapeutic equipment.Its main feature is to be provided with main frame at the middle part of cover body, and the cover body is provided with the spectrum therapy body, and the spectrum therapy body is divided into HONGGUANG, two kinds of spectrum of infrared light.Be provided with the Low Medium Frequency maker in the main frame, the spectrum generator, panel, with Low Medium Frequency treatment body, the spectrum therapy body connects respectively.Because infrared spectrum, red spectral, three sections wave spectrums of Low Medium Frequency spectrum are ideally combined, make these three sections wave spectrums in common therapeutic domain, realize bringing out the best in each other, have complementary advantages the purpose of resource-sharing.Promote the blood of human body circulation thereby reach, activating cell improves functions such as immunity adjustment nervous system.

These traditional treatment and equipment only guarantee human body is applied a certain amount of electromagnetic wave; Electromagnetic wave waveform and light intensity there is not special definition; Its intensity is only considered safety, and the waveform that concrete disease adopts is not significantly distinguished, and therapeutic effect does not obtain the related medical checking yet; Have certain blindness, security reliability is poor.

At present, cardiovascular disease for example heart disease, hypertension is a human puzzlement greatly, implements verifiedly, only depend on Drug therapy cardiovascular disease effect unsatisfactory, except Drug therapy, does not also have this type of special for treating disease.

The utility model content

This utility model technical problem to be solved provides a kind of cardiovascular disease cell excitation therapeutic instrument, and it uses specific waveform treatment and improves concrete disease-cardiovascular disease.

In order to realize above-mentioned utility model purpose, the cardiovascular disease cell excitation therapeutic instrument that this utility model provides is characterized in that it comprises

One housing, and

One is installed in the said housing and can applies electromagnetic electromagnetic wave generator to human body; The electric current time-varying current waveform that generates electromagnetic waves in the said electromagnetic wave generator is:

$I\left(t\right)=\left\{\begin{array}{cc}0,& t<0\\ I_{\max }\&times;(1-(1-e^{t/\mathrm{\&tau;}}))& \\ 0,& t>{\mathrm{<figure-callout\; id="1"\; label="t"\; filenames="HDA0000158741940000022.png,HDA0000158741940000031.png"\; state="\{\{state\}\}">t</figure-callout>}}_1\end{array}\right.$ 0≤t≤t ₁

Wherein,

-τ equals the time constant that waveform generator produces

-t is time (point)

-(t ₁-t) be the persistent period or the working time of pulse

-I _MaxIt is the electric current that flows through the maximum of circuit

And, τ and t ₁Scope:

a)300μsec≤τ≤0.1sec

b)5msec≤t ₁≤0.1sec

c)50mA≤Imax≤200mA。

Further; Said electromagnetic wave generator comprises a CPU, a digital to analog converter and a multiplexer and a current inductor; Said CPU is exported pulse width adjustment waveform (PWM); This pulse width adjustment waveform is input to said digital to analog converter; Said digital to analog converter produces the voltage waveform that voltage institute's time changes, and through said multiplexer said voltage waveform is transformed into above-mentioned current waveform again, said current waveform be input in the said current inductor in case the electromagnetism electromagnetic wave (field) that produces an individual features (PEMF).

The cardiovascular disease cell excitation therapeutic instrument that this utility model provides is owing to adopt the electromagnetic wave of customization; This electromagnetism wave energy has therapeutical effect preferably to specific disorders-cardiovascular disease; Particularly hypertension and heart disease are had excellent curative, and this therapeutic effect has obtained the checking of a considerable amount of contrast tests.

Description of drawings

Fig. 1 is the structural representation that the cardiovascular disease cell of this utility model encourages an embodiment of therapeutic instrument;

Fig. 2 is that electromagnetic electric current time-varying current oscillogram is treated in the generation that is used for of the cardiovascular disease cell excitation therapeutic instrument of this utility model;

Fig. 3 is a circuit diagram that produces this pulse width adjustment waveform (PWM);

Fig. 4 is the cell in vitro result of the test that the essential hypertension rat test is obtained;

Fig. 5-the 9th is to the result that obviously descends of the blood pressure after the original hypertensive rat treatment.

The specific embodiment

Below in conjunction with accompanying drawing, the embodiment of this utility model is described in detail.

Referring to Fig. 1, the cardiovascular disease cell of this utility model excitation therapeutic instrument comprises a CPU (CPU) 50, linking to each other with CPU 50 is used for human body condition detection apparatus, and the external supply unit that communicates device, the one or more bioelectromagnetics wave producer of contact and be used for providing electric power to said apparatus of monitoring human situation.Each this bioelectromagnetics wave producer links to each other with said CPU, and said CPU 50 can be exported pulse width adjustment waveform (PWM) as required.Above-mentioned device is installed in (not shown) in the housing.

Certainly, pulse width adjustment waveform (PWM) also can produce through hardware.Fig. 3 is a circuit diagram that produces this pulse width adjustment waveform (PWM).Among the figure, R1, R2, R6, C1, D1, D2 and CP1 form a sawtooth generator.CP2 and R7 constitute an analog comparater.CP2 will compare the modulation electric of the sawtooth waveforms of positive input, will produce a pulse width at the outfan of CP2 like this and adjust avette ripple.

Concerning the general field personnel of this area, how selecting suitable substance P WM to produce the electromagnetic wave that needs has been common sense at present, on market, also can provide through corresponding electronic device.

In addition, in this embodiment, the cardiovascular disease cell of this utility model excitation therapeutic instrument can pass through common communication equipment; For example; The antenna and the related communication module of the mobile phone that cordless communication network connects, or the wired or wireless network connection device that is connected with the Internet communicate contact with the external world; Receive associated control signal, or download relative program etc.

Supply unit adopts battery, for example common lithium battery, and it comprises battery charger 51, battery 52, power supply module 521,522,523.Battery charger 51 is external or configuration, can continue supply to battery 52 electric power that guarantees battery 52 that charges.Battery 52 is supplied power to each parts of cardiovascular disease cell excitation therapeutic instrument respectively through power supply module 521,522,523.Battery charger 51 is connected so that charge with extraneous power supply through power connector end mouth 531.

Electromagnetic wave generator is by waveform multiplexer (MULTIPLEXER) 56, driver 561 and 562, form with the waveform generator 581 and 582 that driver 561 links to each other with 562.D/A converter module 55 receives the pulse width adjustment waveform (PWM) that CPU 50 needs, and exports the time dependent voltage waveform of a mimic voltage.Multiplexer 56 also is an equipment common on the market, and the voltage waveform that it receives D/A converter module 55 inputs is divided into some identical signals.Present embodiment comprises two-way electromagnetic wave outut device; Waveform multiplexer 56 exportable two-way waveform modelling voltage signals are input to respectively in driver 561 and 562, and driver 561 and 562 current wave of driving and generating waveform such as Fig. 2 waveform generator 581 and 582 of flowing through respectively produces.Waveform generator 581 and 582 can adopt current inductor or coil inductor (inductor), and it comes down to a coil, and electric current is flowed through, and it is the electromagnetic wave that can produce certain intensity.Present embodiment is to produce two groups of current waves, and these two kinds of electromagnetic waves can be same waveform as or different wave.In addition, waveform multiplexer 56 can produce one the road or the above control impuls of two-way equally as required, produces one or more current wave through one or more driver.Waveform generator 581 and 582 is arranged to through configuration can be with the relatively low intravital blood circulation of frequency pulse magnetic stimulation patient; Such low frequency usually can be between about 10Hz and 200Hz, more typically between 20Hz and 120Hz, even; More typically between 20Hz and 40Hz; And in a specific case, approximately or be essentially 30Hz (for example, 30Hz+ or-3Hz).

Central control unit 50 is the work of above-mentioned each parts of may command, and central control unit 50 also can adopt control units such as microprocessor or single-chip microcomputer.

In the present embodiment, the human body condition detection apparatus adopts a heartbeat sensor 58 and motion sensor 54.Heartbeat sensor 58 can be measured the cardiac rate of human body, and is input to central control unit 50.Motion sensor 54 can in time be measured kinetic characteristics such as the vibration, acceleration of health, for example how to move and motion feature in a period of time, and exercise data during this period of time draws the data of other health of a part of human body through analyzing and handling.

Above-mentioned motion sensor 54 can adopt motion accelerometer (accelerometer); Accelerometer is a kind of very sensitive motion sensor; When holding this equipment in patient or the user hands and when static; It can see most of microvibration (for example heart beating or blood flow pulse) from the person; And patient's heart beating spectrum will embed in this vibration signal, and the signal of detection is input to central control unit 50 and passes through Digital Signal Processing (DSP) technology detected and extracted user from whole signals heart beating spectrum or pulse.

In addition, central control unit 50 can be with the for example relevant patient's of above-mentioned human body condition information treatment history, the electrical property of treating on sick body and/or the sick body; These factors of position (passages through which vital energy circulates point) and other certain factor; Skin thickness for example, the adipose tissue mass under the treatment position, normality cardiac rate; And/or the electromagnetic wave waveform that adapts of other physical factors customizations or adjustment and patient, better to guarantee therapeutic effect.

Liquid crystal display (LCD) 551 is used for showing the duty of whole cell stimuli terminal or the running parameter of each associated components.

Function connectivity port 532 is used for being connected with extraneous, so as from the external world input data or download so that the functional part of cell stimuli terminal, for example recreation, clock, communication etc. are worked.

Power connector end mouth 531 is used to connect the power supply power supply.

Battery electric quantity detector 53 is used to monitor whole system electric weight operating position.

Fig. 2 is that electromagnetic electric current time-varying current oscillogram is treated in the generation that is used for of the cardiovascular disease cell excitation therapeutic instrument of this utility model.As mentioned above, in a single day this current waveform flows through coil inductor 581,582 and will produce and can be used to treat the electromagnetic wave that the people worries angiopathy accordingly.

The mathematical formulae of the current waveform among Fig. 2 is:

$I\left(t\right)=\left\{\begin{array}{cc}0,& t<0\\ I_{\max }\&times;(1-(1-e^{t/\mathrm{\&tau;}})),& \\ 0,& t>{\mathrm{<figure-callout\; id="1"\; label="t"\; filenames="HDA0000158741940000022.png,HDA0000158741940000031.png"\; state="\{\{state\}\}">t</figure-callout>}}_1\end{array}\right.$ 0≤t≤t ₁

Wherein:

-τ equals the time constant that waveform generator produces

-t is time (point)

-(t ₁-t) be the persistent period or the working time of pulse

-I _MaxIt is the electric current that flows through the maximum of circuit

And: τ and t ₁Scope:

a)300μsec≤τ≤0.1sec

b)1msec≤t ₁≤0.1sec

In above-mentioned formula and Fig. 2, the size of Imax has determined to flow through waveform generator 581 and 582 the size of current among Fig. 1, has also directly determined the electromagnetic intensity of treatment.The major contribution of this utility model is through a large amount of experiments; On the basis of above-mentioned waveform; The scope of finding Imax just can reach certain therapeutic effect between 50mA-200mA; And when the scope of Imax is between 75mA and 110mA, can reach preferable therapeutic effect, concrete therapeutic effect can obtain checking from following experiment.

To those skilled in the art; The current waveform that provides according to this utility model; The pulse width that can utilize central control unit 50 to produce suitable needs is easily adjusted waveform (PWM), and, can produce corresponding electromagnetic wave according to the disclosed current waveform of this utility model.

Certainly, to those skilled in the art, can adopt software or hardware to produce current wave shown in Figure 2.

And this utility model can produce a kind of electromagnetic wave human body is treated, and also can adopt two or more electromagnetic wave simultaneously human body to be treated, and the mode of treatment can according to circumstances be selected voluntarily.

The electromagnetic wave of the cardiovascular disease cell excitation therapeutic instrument of this utility model both can be stored in the therapeutic instrument, also can download from the outside through wireless network, and can constantly adjust variation.

Principle analysis:

The principle that the cardiovascular disease cell excitation therapeutic instrument that this utility model provides has adopted magnetic to change electricity clinically discharges a pulsed magnetic field specific, that can produce cardiovascular regenerated signal waveform at the human body internal induction outside human body.The PEMF pulsed magnetic field is in human body; Produce cardiovascular simulation regenerative current signal; This signal is passed to brain through nervous system, and brain starts inherent cardiovascular Regeneration and Repair mechanism in the body, thereby promotes vascular endothelial cell to quicken division; Former embryonic cell is assembled the vascular injury place; Endotheliocyte acceleration of growth, blood capillary regeneration, NO are discharged, thereby make arteriosclerosis, blood pressure drops, thromboembolism, damaged myocardium Regeneration and Repair, cardiovascular system diseases is played prevention and therapeutic effect.

The cell in vitro test:

Referring to Fig. 4, Fudan University in Shanghai pharmaceutical college adopts the strength arterial cannulation through carrying out the essential hypertension rat test, detects its blood pressure situation (n=1) after cardiovascular disease cell excitation therapeutic instrument stimulates.This cell in vitro result of the test shows that through 8 minutes the once activation of cardiovascular disease cell excitation therapeutic instrument of this utility model, the human vas endothelial cell growth speed of In vitro culture heightens, up to 25%.

Animal experiment:

Referring to Fig. 5-9, Fudan University in Shanghai pharmaceutical college animal test results shows that after three days the treatment of cardiovascular disease cell excitation therapeutic instrument of original hypertensive rat through the different parameters of this utility model, the test rat blood pressure obviously descends.

In this utility model; Above-mentioned electromagnetic wave generator configuration is arranged to and can be stimulated the intravital blood circulation of patient with relatively low pulse electromagnetic field (PEMF); Here, such low frequency usually can be between about 10Hz and 200Hz, more typically between 20Hz and 120Hz; Even more typically between 20Hz and 40Hz, best is between the 60HZ at 15HZ.And in a specific case, approximately or be actually 30Hz (for example, 30Hz and+-3Hz).

The above results further shows; If the current wave that generates electromagnetic waves of the cardiovascular disease cell of this utility model excitation therapeutic instrument is the waveform of Fig. 2; The mathematical formulae of this waveform is following, and common ventricular premature contraction, conduction block, hypertension are all had preferable therapeutic effect:

$I\left(t\right)=\left\{\begin{array}{cc}0,& t<0\\ I_{\max }\&times;(1-(1-e^{t/\mathrm{\&tau;}})),& \\ 0,& t>{\mathrm{<figure-callout\; id="1"\; label="t"\; filenames="HDA0000158741940000022.png,HDA0000158741940000031.png"\; state="\{\{state\}\}">t</figure-callout>}}_1\end{array}\right.$ 0≤t≤t ₁

Wherein:

-τ equals the time constant that waveform generator produces

-t is time (point)

-(t ₁-t) be the persistent period or the working time of pulse

-I _MaxIt is the electric current that flows through the maximum of circuit

And, τ and t ₁Scope:

a)300μsec≤τ≤0.1sec

b)5msec≤t ₁≤0.01sec

c)50mA≤Imax≤200mA。

Further again, the scope of said Imax is between 75mA and 110mA, will make therapeutic effect better.

Further again, same, if said τ and t ₁Scope following, then therapeutic effect can reach preferable relatively degree:

a)8.33msec≤τ≤33.33msec

b)1.25msec≤t ₁≤2.0msec

The cardiovascular disease cell excitation therapeutic instrument of this utility model all has significant curative effect to the patient's of all ages and classes cardiovascular disease.

The frequency range of the use of the cardiovascular disease cell of this utility model excitation therapeutic instrument between 20Hz and 120Hz, more typically between 20Hz and 40Hz, and in a specific case, approximately or be essentially 30Hz (for example, 30Hz+ or-3Hz).

Also have, this utility model can be given the treatment personnel, and for example medical worker's (or oneself manages the personnel of treatment) provides can waveform frequency, waveform shape and the wave-shape amplitude in magnetic field be modified as the situation that can be fit to patient's diagnosis.Multiple different wave also can or alternately be used, and certain a part of waveform that is applied to patient body or passages through which vital energy circulates can be different from the different piece that is applied to this patient body or the waveform of passages through which vital energy circulates.In addition, when possessing many portable sets, they can be applied to the different piece of human body or different passages through which vital energy circulates with the waveform that can dynamically make amendment simultaneously with identical or more typical different waveform.What is more, and multiple devices can use with the distinct device by a certain mode phasing, so that only have the selected subclass equipment in one or all devices can move (emission electromagnetism or EM radiation) in the identical time.Like this, multiple devices can be applied on the different passages through which vital energy circulates of single patient body and control (for example through intervalometer, or local wireless or wired connection) operation according to the programming therapeutic scheme.

More than show and described ultimate principle of this utility model and the advantage of principal character and this utility model.Those skilled in the art should understand; This utility model is not restricted to the described embodiments; The principle of describing in the foregoing description and the description that this utility model just is described; Under the prerequisite that does not break away from this utility model spirit and scope, this utility model also has various changes and modifications, and these variations and improvement all fall in the protection domain of this utility model that requires protection.This utility model requires protection domain to be limited appending claims.

Claims (7)

1. a cardiovascular disease cell encourages therapeutic instrument; It is characterized in that; Comprise that a housing, is installed in that said shell is intravital can to apply electromagnetic electromagnetic wave generator to human body; Said electromagnetic wave generator comprises a CPU, a digital to analog converter and a multiplexer and a current inductor, and said CPU is exported pulse width adjustment waveform, and this pulse width adjustment waveform is input to said digital to analog converter; Said digital to analog converter produces the voltage waveform that voltage institute's time changes, and through said multiplexer said voltage waveform is transformed into said current waveform again.

2. cardiovascular disease cell excitation therapeutic instrument as claimed in claim 1 is characterized in that the electric current time-varying current waveform that generates electromagnetic waves of said electromagnetic wave generator is:

$I\left(t\right)=\left\{\begin{array}{cc}0,& t<0\\ I_{\max }\&times;(1-(1-e^{t/\mathrm{\&tau;}})),& \\ 0,& t>t_1\end{array}\right.$ 0≤t≤t ₁

Wherein,

-τ equals the time constant that waveform generator produces

-t is time (point)

-(t ₁-t) be the persistent period or the working time of pulse

-I _MaxIt is the electric current that flows through the maximum of circuit

And, τ and t ₁Scope:

a)300μsec≤τ≤0.1sec

b)5msec≤t ₁≤0.1sec

c)50mA≤Imax≤200mA。

3. cardiovascular disease cell excitation therapeutic instrument as claimed in claim 2 is characterized in that the scope of said Imax is between 75mA and 110mA.

4. cardiovascular disease cell excitation therapeutic instrument as claimed in claim 2 is characterized in that said τ and t ₁Scope following:

a)8.33msec≤τ≤33.33msec

b)1.25msec≤t ₁≤2.0msec

5. cardiovascular disease cell excitation therapeutic instrument as claimed in claim 1 is characterized in that said frequency is between 20Hz and the 120Hz.

6. cardiovascular disease cell excitation therapeutic instrument as claimed in claim 5 is characterized in that said frequency is between 20Hz and 40Hz.

7. cardiovascular disease cell excitation therapeutic instrument as claimed in claim 6 is characterized in that said frequency is 30Hz.

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