CN202497501U - Novel hydrogel scar plaster - Google Patents

Abstract

Provided is a novel hydrogel scar plaster, which is composed of a support layer, a hydrogel layer and an isolation layer, and is characterized in that: the support layer is coated by the hydrogel layer, and the other side of the hydrogel layer is coated by the isolation layer.

Description

A kind of novel hydrogel cicatrix is pasted

Technical field

This utility model relates to medical and beauty treatment fields, relates to a kind of the softening of the various cicatrixes of skin surface that be applied to specifically, suppresses hypertrophy, flattens, antipruritic, the preparation for external application to skin that fades.

Background technology

Cicatrix is the inevitable outcome after the various wound healing, if but healing is not enough or healing is excessive, promptly can produce cicatrix, if trace continues propagation, can become hypertrophic cicatrix.According to the various extent of injury that cause damage factor, and the body constitution of wounded body, can cause following several types of cicatrixes: show shallow scars, atrophic cicatrix, depressed scar, hypertrophic cicatrix, keloid, the people of cicatrix body constitution particularly, cicatrix is especially obvious.Cicatrix can bring great inconvenience to the patient, and the hypertrophic cicatrix as burn causes can cause local pruritus, pain, even dysfunction, seriously perplexs the patient.And the control of cicatrix is a difficult problem of medical domain always, though injection hormone effect is better in the cicatrix, the early stage sufferings remission of cicatrix is not obvious, is not suitable for the control of large tracts of land cicatrix, and side effect is big, and the patient is difficult for accepting.

Silicon gel cicatrix pastes except that invalid to the sufferings of cicatrix; Various treating acnes are had reasonable therapeutic effect, can better soften cicatrix, make cicatrix flatten, fade; And side effect is little, and its mechanism that mainly acts on is hydration, mechanical pressure and electrostatic field.The research demonstration, and half of the too late normal skin of silicate gel film moisture-vapor transmission (Liu Wenge. the Li Sujuan chief editor. cicatrix prophylactic treatment [M]. Beijing: publish the learning centre, 2000:19.); Because water evaporates is restricted, keratodermatitis water retention phenomenon takes place, reduce the demand of blood capillary; Thereby the hypertrophy that suppresses blood capillary; Reduce the deposition of collagen, thus reach the control scar hyperplasia purpose (Li Huiyuan. blood vessel and bioactie agent thereof and scar hyperplasia [J]. Chinese clinical rehabilitation, 2002; 6 (20): 3080-3081.), the mechanism of hydration that Here it is.As for the mechanical pressure effect, there is the scholar to think, silicate gel film sticks and can produce the mechanical pressure that continues to skin; Cause the local organization defective, reduce tissue metabolism and lead, improve collagenase activity in the wound; Be reduced to fibrocyte content, enlarge intercellular substance, be beneficial to the collagen bundle and disperse and regular distribution (Nie Xue; Open refined word; Xing Jinxia. silicate gel film adds Elastic bandage Combined application treatment hypertrophic cicatrix [J]. and Chinese clinical rehabilitation, 2005.9 (10): 1), and the collagen fiber confusion is one of key character of hypertrophic cicatrix.

But above-mentioned silicon gel cicatrix pastes; Some problems below existing: 1, a little less than the hydration: at first, moisture-free in this series products, its hydration is to receive stopping of silicon gel-like product through the moisture of skin evaporation; The passive retention of moisture is in cicatrix skin, and hydration is limited; Secondly, because some damages are heavier, like III degree burn, destructions such as sweat gland of skin, water evaporates is limited, and hydration is weakened greatly; 2, the cicatrix body is lacked defencive function: cicatrix, particularly serious hypertrophic cicatrix and keloid, its surperficial skin often has breakage; Possibly there are minute fissure or infected by microbes; And silicon gel-like product lacks antibacterial or sterilizing function, and because this series products sticks the cicatrix place, because humidity, temperature are higher relatively; Cause growing of microorganism easily, cause cicatrix to be inflamed; 3, use repeatedly, influence health and hydration effect: silicon gel-like cicatrix pastes on the description and generally shows, can use repeatedly; Therefore; This series products and skin contact, easily adhesion of microorganisms, skin oil and fat, scurf influence product health and hydration; 4, drug combination difficulty: be difficult to make up, comprise other in silicon gel cicatrix pastes and have the composition that suppresses cicatrix, drug combination improves curative effect.Utilize around the two-layer silicon gel glued membrane with the fluid sealant sealing though in patent 03115384.4, mention, intermediary lacuna medication stores adds medicine, and medicine can see through the silicate gel film surface that penetrates to the skin, and plays the purpose that administration increases curative effect.Though silicate gel film has the ability of certain permeate water steam; Yet medicine or other are to the molecular weight of cicatrix effective ingredient tens times of hydrones normally; Or hundred times; Therefore even the silicon gel has the logical permeability of film medicine, also very limited, not very desirable with silicate gel film as the carrier of Transdermal absorption.

Hydrogel patch technology (or claiming the cataplasma technology) as far back as the seventies in 20th century Japan at first will a kind of ancient dosage form poultice transform and be developed to present cataplasma, be a kind of water content height, good biocompatibility, content of dispersion greatly, the transdermal absorption formulation good to the pharmaceutical pack capacitive.The inventor contrasts hydrogel patch and silicon gel-like cicatrix pastes the back discovery; The base structure of using hydrogel patch to paste as cicatrix; Have silicon gel-like cicatrix and paste the advantage that does not possess: 1,, can reach more than 70% because the hydrogel patch water content is high, can be to cicatrix skin active aquation; The degree of hydration is high, helps softening, flattening of cicatrix more; 2, the hydrogel patch pardon is good, unites use, improves curative effect.Various have inhibiting material to cicatrix; Like chitosan, hyaluronic acid, Aloe, aspirin, retinoic acid, silicone oil, glucocorticoid; And the Chinese medicine class, like Herba Menthae, Borneolum Syntheticum, Herba Centellae, Radix Sophorae Flavescentis, Radix et Caulis Opuntiae Dillenii extract etc., all can be included in the gel layer of hydrogel patch; The associating use improves curative effect; 3, content of dispersion is high, and the content of dispersion in the hydrogel patch can reach more than 40%; 4, disposable health safe in utilization.Simultaneously similar with silicon gel-like product, cicatrix skin is produced mechanical pressure.Researcher has been consulted domestic and foreign literature and related data, and clearly not proposing with the hydrogel patch is the hydrogel cicatrix subsides relevant report on basis.

Summary of the invention

The purpose of this utility model be provide to the deficiency of prior art a kind of novel, have initiatively strong hydration, can contain the various characteristics effective ingredient, disposable hydrogel cicatrix pastes.

For reaching the utility model purpose, the technical scheme that this utility model adopts is:

A kind of novel hydrogel cicatrix pastes, and is made up of supporting layer, hydrogel layer and sealing coat, and supporting layer, hydrogel layer and sealing coat be arrangement architecture from the bottom up.

Supporting layer is a kind of in non-woven fabrics, polyurethane film and the nonwoven fabrics composite film.

Nonwoven fabrics composite film is technology such as bonding or hot melt adhesive through glue, covers layer of plastic film in nonwoven surface.

Described sealing coat, a kind of in PE film, the release paper that scribbles silicone oil and the pearly-lustre film.

Beneficial effect of the present invention is mainly reflected in:

1. hydrogel cicatrix of the present invention pastes disposable use, safety and sanitation;

2. hydrogel cicatrix of the present invention pastes good biocompatibility, can not cause the patient to stick position allergy;

3. hydrogel cicatrix of the present invention pastes can take off subsides repeatedly, helps local the observation like this.

Description of drawings

Fig. 1 is this utility model structural representation.

The specific embodiment

Below in conjunction with accompanying drawing this utility model is described further, but the protection domain of this utility model is not limited in this:

A kind of novel hydrogel cicatrix pastes, and is made up of supporting layer 3, hydrogel layer 2 and sealing coat 1, and supporting layer 3, hydrogel layer 2 and sealing coat 1 be arrangement architecture from the bottom up.

Claims (4)

1. a novel hydrogel cicatrix pastes, and is made up of supporting layer, hydrogel layer and sealing coat, it is characterized in that hydrogel layer is coated on the supporting layer, and the hydrogel layer opposite side covers sealing coat.

2. novel hydrogel cicatrix according to claim 1 pastes, and it is characterized in that: supporting layer is a kind of in non-woven fabrics, polyurethane film and the nonwoven fabrics composite film.

3. novel hydrogel cicatrix according to claim 2 pastes, and it is characterized in that: nonwoven fabrics composite film is technology such as bonding or hot melt adhesive through glue, covers layer of plastic film in nonwoven surface.

4. novel hydrogel cicatrix according to claim 1 pastes, and it is characterized in that sealing coat is the PE film, scribbles a kind of in release paper and the pearly-lustre film of silicone oil.

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