CN202446628U

CN202446628U - Local skin anesthesia hot compress piece

Info

Publication number: CN202446628U
Application number: CN2012200219956U
Authority: CN
Inventors: 朱洪远
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-01-18
Filing date: 2012-01-18
Publication date: 2012-09-26
Anticipated expiration: 2022-01-18

Abstract

The utility model relates to a local skin anesthesia hot compress piece. The local skin anesthesia hot compress piece is characterized in that the local skin anesthesia hot compress piece comprises flaky base material, a heat-producing chip, an anesthetic liposome layer and a macromolecular glucoprotein layer, wherein the flaky base material comprises a first surface and a second surface; the heat-producing chip is adhered to the first surface of the flaky base material; the anesthetic liposome layer is provided with liposome on which anesthetic is coated; one side surface of the anesthetic liposome layer is covered on the second surface of the flaky base material; and the macromolecular glucoprotein layer is covered on the other side surface of the anesthetic liposome layer. The local skin anesthesia hot compress piece has the benefits that the infiltration capacity of anesthetic is improved by improving the medicament layer structure of anesthetic, local skin temperature is increased through the heat-producing chip, and further anesthetic absorption is accelerated, so that the anesthetic time is obviously reduced, and the trouble of preservative film packing is cancelled.

Description

Local skin anesthesia hot compress sheet

Affiliated technical field

This utility model relates to the medical anesthesia field, and is relevant with local skin anesthesia articles for use, particularly about a kind of local skin anesthesia hot compress sheet.

Background technology

Usually, when department of dermatologry and plastic surgery carry out the minor operation of skin shallow-layers such as laser surgery or high-frequency electrical burning, be to reduce the pain of being brought because of operation, generally can be before operation smear skin and anaesthetize ointment executing the art position earlier.Because human body skin mainly is made up of epidermis, corium and three parts of subcutaneous tissue, wherein the outermost layer of epidermal area is covered by horny layer, the obstacle of maximum when being the medicine transdermal.Because horny layer belongs to hydrophobicity and electronegative, therefore the percutaneous of water soluble drug is penetrated and cause very big obstruction.Because this barrier characteristics of skin makes the dosage of anesthetis transdermal be difficult to reach the valid density of anesthesia easily.Therefore, reduce the method for operation pain sense with skin anesthesia ointment, usually a large amount of anesthesia ointment is applied in operative site after, needs of patients waits for that for a long time medicine plays a role.Clinically, be time that shorten to wait for that anesthesia comes into force, generally skin be coated with spread anesthetics cream after, further seal this position, to promote narcotic absorption with preservative film.Though seeing through preservative film can be so that local fervescence, increasing narcotic infiltration rate, yet this kind not only bothers and waiting time that anesthesia comes into force still long (needing 30 to 60 minutes approximately) with the mode of preservative film parcel.When wait as long for anesthetis comes into force, can increase the anxiety sense of patient with operation virtually.

In view of this, after the applicant grinds materia medica and materialogy principle deeply,, propose a kind ofly can make skin fast Absorption anesthetis, and can keep the scheme of the local anesthesia effect of certain hour in conjunction with clinical practice.

Summary of the invention

The purpose of this utility model is to provide a kind of local skin anesthesia hot compress sheet, and the contained anesthetis of this hot compress sheet can be absorbed by skin fast, shortens and anaesthetizes time, and can keep the anaesthetic effect of certain hour.

In order to achieve the above object, this utility model provides a kind of local skin anesthesia hot compress sheet, it is characterized in that: comprise:

One lamellar base material; Described flat substrates comprises first surface and second surface;

One euthermic chip, described euthermic chip fits in the first surface of said flat substrates;

One anesthetis liposome layer, it has and is coated with narcotic liposome, and a side surface of this anesthetis liposome layer is the second surface that is coated in this flat substrates;

And a macromolecule glucoprotein layer, it is to be covered on the opposite side surface of this anesthetis liposome layer.

Further, described euthermic chip is provided with the avulsion ear.

Further, the particle diameter of this liposome is a nano-scale.

For this utility model, described liposome begins to be widely used in doing the carrier of drug release control in the nineties.Liposome has special hollow ball structure, in the structure of liposome lipid bilayer, can keep hydrophobic drug; In its internal water phase region, can coat water soluble drug.The most frequently used lipid of preparation liposome is a lecithin, and its main phospholipid composition is a phosphatidylcholine, and the liposome that uses natural phospholipid matter to process has excellent biological compatibility and Biodegradable.

This utility model is the anesthetis that coats high dose with liposome; Utilize the lipid bilayer similar performance of liposome and keratodermatitis; Can be easy to and the horny layer effect; And as far as skin is the characteristic that can transport the non-toxic carrier of material, and the high dose anesthetis of its coating is transported to surface and deep skin.

For this utility model, described macromolecule glucoprotein claims that again albumen gathers candy, some peptide chains of covalent bond on some position of candy and the complex that generates has stronger hydrophilic.In this utility model; Be to utilize its water-wet behavior, and not can with the advantage of liposome effect, make this macromolecule glucoprotein be covered on this anesthetis liposome layer; Make its protective layer that becomes the liposome in this anesthetis liposome layer, to prolong the holding time of this local skin anesthesia hot compress sheet.

For this utility model, the exothermic mixture of described euthermic chip can be electronation Soft Release thermit powder or controllable type oxygen absorbent, and its principle is to utilize with the oxygen reaction to discharge heat energy.

The beneficial effect of this utility model is through improving narcotic medicament layer structure, to increase narcotic penetrating power; And through the configuration euthermic chip, the local skin temperature that improves is further accelerated anesthetis and is absorbed; Therefore obviously shorten anesthesia duration, and eliminate the trouble of parcel preservative film.

Description of drawings

Fig. 1 is the cross-sectional view of this utility model.

Fig. 2 is the avulsion ear structure sketch map of this utility model.

The specific embodiment

Below in conjunction with accompanying drawing and embodiment this utility model is further specified.

Consult Fig. 1 and Fig. 2, the embodiment of this utility model provides a kind of local skin anesthesia hot compress sheet, and it comprises: a lamellar base material 1; Described flat substrates 1 comprises first surface 10 and second surface 11; One euthermic chip 2, described euthermic chip 2 fits in the first surface 10 of said flat substrates 1; One anesthetis liposome layer 3, it has the liposome 30 that is coated with anesthetis 4, and a side surface 31 of this anesthetis liposome layer 3 is the second surfaces 11 that are coated in this flat substrates 1; The particle diameter of described liposome 30 is nano-scales.And a macromolecule glucoprotein layer 5, it is to be covered on the opposite side surface of this anesthetis liposome layer 3 32.

As preferred embodiment, described euthermic chip 2 is provided with avulsion ear 20.

For present embodiment, this flat substrates 1 can be adhesive-bonded fabric, cotton or paper etc., uses for liposome layer 3 to be attached on its surface; When anesthesia, and can provide a physical property contention effect, impel this liposome 30 and skin surface fusing penetrating keratodermatitis in this liposome layer 3.

In embodiment; Phospholipid is scattered in the aqueous solution can form the hollow sphere with double membrane structure; This anesthetis 4 is coated in this liposome 30; And make this liposome that is coated with high dose anesthetis 4 30 evenly be coated in a side surface 11 of this flat substrates 1, to form this anesthetis liposome layer 3.Aforesaid liposome 30 is nano-scales, and its size is between 200 and 400 nanometers (nm).

In use, first cleaning skin sprays an amount of water at need at the anesthesia predetermined position, then the screening glass of euthermic chip is torn, and directly sticks predetermined position at this hot compress sheet and gets final product.Because the macromolecule glucoprotein has stronger hydrophilic, therefore, after this macromolecule glucoprotein layer 5 touches the water of skin surface, just can dissolve immediately, and can not act on this liposome 30.At this moment, the many liposomes 30 in this anesthetis liposome layer 3 just can contact with skin, and a large amount of liposomes 30 discharge the high concentration anesthetis 4 that it coated after can being pinned by skin epidermis fast earlier again; And euthermic chip 2 generation heats, the temperature of raising local skin is further accelerated narcotic infiltration rate, obviously shortens the anesthesia entry-into-force time, and the trouble of preservative film is wrapped up in elimination.After reaching anaesthetic effect, hands is held the avulsion ear 20 of euthermic chip 2, the patch of can tearing easily.

The above content that discloses; It is the preferable specific embodiment of this utility model; The purpose of all and this utility model is equivalent or impartial content with the effect that can reach; And for those skilled in the art can unlabored simple and easy modification, modification, improvement or variation, all should not break away from the patent right scope of opinion that this utility model is contained.

Claims

1. a local skin is anaesthetized the hot compress sheet, it is characterized in that: comprise:

2. local skin anesthesia hot compress sheet as claimed in claim 1, it is characterized in that: described euthermic chip is provided with the avulsion ear.

3. local skin anesthesia hot compress sheet as claimed in claim 1, it is characterized in that: the particle diameter of this liposome is a nano-scale.