KR100976418B1 - Mask pack using the water-vapor controllable sheet - Google Patents

Abstract

The present invention relates to a mask pack using a sheet having moisture unidirectional permeability. Specifically, the mask pack has a skin absorption promoting effect of the active ingredient by adjusting the directionality related to water permeation, or gives a heat and cold feeling to the skin to provide a skin soothing effect. According to the present invention, a functional mask pack having a relatively low density and hydrophilicity, a water diffusion layer (7) having a relatively low density and hydrophilicity, and a medium having a medium density and hydrophilicity thereof. There is provided a mask pack comprising a mask sheet on which a moisture transfer layer 6 is laminated, the mask sheet being laminated therefrom in the order of a water diffusion layer 5, a water transition layer 6, and a water absorption layer 7. If it is a structure that is used as a mask pack for promoting the absorption of the active ingredient, the structure is laminated in the order of the water absorption layer (7), the water transition layer (6), the water diffusion layer (5) from the inside Used as a mask pack for skin soothing, the mask pack of the present invention is a useful invention that exhibits high active ingredient absorption and skin soothing effect due to the water movement effect of a unique composition, and can be reused to prevent waste of resources. Contribute to environmental protection.

Unidirectional moisture movement, skin penetration enhancement, skin soothing effect, mask pack

Description

Mask pack using sheet directional to moisture permeation {MASK PACK USING THE WATER-VAPOR CONTROLLABLE SHEET}

The present invention relates to a mask pack using a sheet having a direction to moisture permeation, and more particularly includes a mask sheet composed of a water absorbing layer, a water transition layer, and a water diffusion layer, and the difference in hydrophilicity and density of each layer. The present invention relates to a mask pack which promotes skin absorption of active ingredients such as cosmetics and drugs by using one-way mobility of moisture, and exhibits a cosmetic effect, imparts a cooling heat to irritated skin and exerts a soothing effect.

Recently, due to the development of medical technology and life science technology, drugs or bioactive substances with large molecular weight or polarity are constantly being developed. However, these drugs or physiologically active substances have problems such as difficulty in maintaining effective blood concentration during oral administration or rapid degeneration by enzymes in the gastrointestinal tract. Therefore, unlike conventional delivery methods such as oral administration, researches to actively improve the bioavailability and therapeutic effect of drugs inactivated by metabolic processes in the gastrointestinal tract using transdermal administration methods that deliver drugs through the skin are actively made. ought. Transdermal administration can be administered to patients who are difficult to oral administration, there is an advantage in that the rate of absorption can be adjusted in terms of formulation. In addition, it is easy to start and stop drug administration, and it is convenient to administer the drug without delivering pain to the whole body, unlike injection, so the research is continuously conducted with high interest not only in pharmacy field but also in cosmetic and skin care related fields. have.

Transdermal drug delivery is difficult due to the barrier function of the stratum corneum, and chemical, mechanical, and physical permeation enhancement methods have been studied to overcome this problem. Among the chemical methods of transdermal delivery, urea and salicylic acid are most commonly used to break down the stratum corneum and increase water content to promote absorption. Urea is commercially available as a 10% cream and increases the water content of keratin and increases the percutaneous absorption of certain ingredients. In addition, there are various types of compounds as absorption accelerators, among which alcohols (alcohol) and glycols (glycols) are known to promote transdermal absorption of various drugs, but are volatile and aromatic substances. Recently, essential oils such as jojoba oil, almond oil, evening primrose oil, camellia oil, olive oil, sunflower oil, avocado oil, castor oil, etc., which have good skin absorption properties, are also attracting much attention. However, these absorption accelerators not only damage the skin barrier but also have a problem that the action is concentration-dependent and causes a strong skin irritation at the necessary concentration to enhance skin penetration.

In addition to these chemical methods, there is a growing interest in the efficient delivery of active materials, and the method of physical acceleration using direct current, high voltage current, high frequency current, magnetic field, ultrasound, laser, etc. and mechanical acceleration methods such as suction, microneedle, skin peeling, and skin puncture. There is an active research on the method of promoting transdermal delivery.

Physical promotion methods for enhancing transdermal administration include recently introduced iontoporesis, sonophoresis, electroporation, heat and high frequency energy, and the like. In case of applying positive current from the electrode, iontophoresis causes the positively charged drugs dissolved in the liquid to diffuse into the skin tissue by the electric repulsive force, and in the case of the negatively charged drugs, the negative current flows. To achieve the same purpose. Sonoforesis is a technology that penetrates the drug by making a small hole in the skin surface by the vibration of the acoustic energy using ultrasonic waves. Electroporation is an agent that makes the permeation of drugs possible by applying a high voltage current to living cells instantaneously and repeatedly to form reversible pores.

However, iontophoresis requires an electrolyte that can smooth the flow of current in addition to the effective drug, and in the case of non-ionized or weakly-active drug, iontophoresis shows low skin absorption rate and low skin absorption rate due to low current efficiency. Therefore, there is a problem that does not exhibit a sufficient penetration enhancement effect. In addition, since the composition, concentration, pH and current of the gel for iontophoresis, and the appropriate treatment time must be properly determined, sufficient permeation enhancement effect can be expected, so there are many considerations in manufacturing. In addition, in order for the drug to penetrate the stratum corneum's barrier by direct current, a sufficiently high current must be used. Since direct current continues to move in one direction, direct current can cause electrochemical reactions in tissues, causing redness and burns, and damaging cell membranes.

With the advent of the well-being era, there is a growing interest and demand for health and skin beauty regardless of age or gender. The most important thing in skin care is how deeply penetrates a good substance into the skin to see the efficacy of the substance. However, the physical and chemical transdermal delivery promoting methods as described above give continuous irritation to the skin and cause damage, and thus, a method for increasing the permeability of the active substance without irritation is required.

On the other hand, as a method for keeping the skin healthy from various skin stresses, skin moisturizing techniques for preventing the drying of the skin moisture and improving the water retention ability in the stratum corneum have been mainly used. A method of ultimately increasing water retention in the stratum corneum has been carried out by using a moisture absorbent or a moisture preventive wetting agent. In addition, the claim that differentiation of the stratum corneum is important to prevent drying of the skin moisture has been made, keratin care technology has been developed to promote the normal turnover of the stratum corneum. Recently, in order to meet consumer demands due to the diversification of modern society, functional cosmetics having high physiological activity such as preventing damage caused by ultraviolet rays or removing harmful free radicals have been actively developed.

In particular, in recent years, accelerated skin aging, generation of skin troubles, excessive skin drying and atopy, skin sensitization phenomena are caused by the harmful skin environment, and in particular, many skin problems are caused by stress. In particular, in case of skin problems such as dry skin and atopic dermatitis, the appearance of the skin is not good, and the appearance of the skin is irritated and sensitive even in the process of treating the skin such as chemical peels, physical peels, and laser skin care. Therefore, it is necessary to protect the skin from external exposure. Therefore, in order to show effects such as soothing the skin, shrinking pores, improving wrinkles, and soothing skin burns due to exposure to sunlight, it is necessary to calm the skin by increasing the absorption of the active ingredient into the skin and giving the skin a cool feeling. have.

In order to give the skin a sense of heat, pars and cosmetics used as quasi-drugs contain a small amount of menthol, sorbitol, peppermint oil, etc., which provides a refreshing feeling to the skin, but does not lower the temperature of the actual skin, It is known to cause severe irritation to the skin, so there were many restrictions on its use on the face.

Research on the conventional mask pack has been mainly focused on improving the function through the change and addition of the components contained in the mask pack, the study on the mask sheet substrate was not active. Conventional mask packs were mostly disposable products provided by impregnating cosmetic ingredients on a nonwoven substrate. However, since the disposable mask pack has to be disposed of after one use, there is a problem economically or environmentally.

Accordingly, the present inventors continue to study to overcome the above-mentioned problems, by changing the material and structure of the mask sheet substrate, to increase the transmittance of the active material without irritation to the skin, the present invention relates to a mask pack showing a skin soothing effect The invention was completed.

In order to solve the above problems, in the mask pack applied to the skin, the mask pack comprising a mask sheet having a structure in the moisture absorption layer, the water transition layer, the water diffusion layer and has a directionality in the transmission of water; It aims to provide.

The present invention consists of a moisture diffusion layer, a water transition layer, a water absorption layer in the order from the inside, the density is relatively reduced toward the water diffusion layer, the water transition layer, the water absorption layer, made of a material and structure of the hydrophilicity of the mask sheet Another object of the present invention is to provide a mask pack for promoting skin absorption of the active ingredient contained in the mask pack.

The present invention is made of a moisture absorbing layer, a water transition layer, a water diffusion layer in the order from the inside, the density of the water absorbing layer, the water transition layer, the water diffusion layer, the relative increase in density, and the hydrophilic mask sheet made of a material Another object of the present invention is to provide a mask pack having a cooling effect on the skin by using a soothing effect.

According to the present invention to achieve the above object, there is provided a mask pack comprising a three-layer structure of a water absorption layer, a water transition layer, a water diffusion layer, having a directionality in the transmission of water.

In order to achieve the above object of the present invention, according to the present invention, a moisture diffusion layer, a water transition layer, and a water absorption layer are formed in the order from the inside, and the density decreases toward the water diffusion layer, the water transition layer, and the water absorption layer. In addition, a mask pack including a mask sheet having a material and a structure having reduced hydrophilicity is provided. At this time, in order to improve the adhesion with the skin, the skin adhesion layer may be further formed on the inside of the water diffusion layer. In addition, the mask pack of the present invention may be formed by applying a cosmetic or drug composition containing a cosmetically active ingredient to the mask sheet.

In addition, according to the present invention in order to achieve the above object of the present invention, the moisture absorbing layer, the water transition layer, the water diffusion layer is made from the inside, the density of the water absorbing layer, the water transition layer, the moisture diffusion layer toward the A mask pack is provided that includes a mask sheet that is made of a relatively increased and hydrophilic material and structure. At this time, in order to improve the adhesiveness with the skin, the skin adhesion layer may be further formed on the inside of the moisture absorbing layer. In addition, the mask pack of the present invention may be formed by applying a cosmetic composition exhibiting a soothing effect on the mask sheet.

The mask sheet of the present invention is a water absorbing layer made of a relatively low density and low hydrophilic (hydrophobic) material, a water diffusion layer made of a relatively high density and high hydrophilic material, and a water transition having a medium relative density and hydrophilicity. It is characterized by consisting of a three-layer structure of layers.

Moisture in the fibers generally migrates from low density to high density, from hydrophobic fibers with low moisture content to hydrophilic fibers with high moisture content. The more densely organized the fibers, the narrower the space between the fibers and the capillaries, and the more condensed, the capillary phenomenon causes the moisture to move toward the denser side.

The present invention utilizes such a transfer property of water, and the moisture absorbing layer of the mask sheet of the present invention is preferably a polyolefin-based fiber such as polyethylene having a low moisture content of yarn, and the water diffusion layer has a high hydrophilicity-modified poly of yarn. Fibers of ester, nylon, cotton and the like may be employed, and polyester having a medium hydrophilicity may be employed as the water transition layer.

At this time, if only the relative size order of the hydrophilicity between the layers in the mask sheet according to the present invention is not limited to the selection of the material. This is because the hydrophilicity of the fiber can be adjusted by modifying the fiber or yarn.

In addition, since moisture has a property of moving from low density to high density, the moisture transition layer of the mask sheet of the present invention has a density of 1.2 to 4 times higher than that of the water absorption layer, and the water diffusion layer (the number of fibers per unit area), respectively. It is preferable to have. If the density is less than 1.2 times, the mobility of moisture is weak, and if it exceeds 4 times, there is a difficulty in manufacturing. The density of the fibers can be increased by tapering the yarns or by twisting the yarns. In addition, when using a cross-sectional yarn when weaving the fiber in relation to the movement of water, it is possible to promote the movement of water by capillary action.

In the mask sheet of the present invention, the moisture is absorbed from the moisture absorbing layer according to the moisture transfer characteristic, and the moisture is transferred to the moisture diffusion layer through the moisture transfer layer. In the present invention, by changing the laminated structure of the mask sheet, it is possible to apply to a mask pack having a function of promoting the skin absorption of the active ingredient, or a mask pack having a skin soothing function by imparting a cooling heat to the skin.

In the case of the active ingredient skin absorption promoting mask pack according to an embodiment of the present invention, the mask sheet, which is the base material, is formed by being laminated in the order of a moisture diffusion layer, a water transition layer, and a water absorption layer from the inside, and a water absorption layer and a water transition layer. As the layer and the water diffusion layer increase in density and have a hydrophilic material and structure, the water moves from the outside to the inside, and the active ingredients contained in the mask pack also move with the water, which is applied to the skin. The amount of ingredients will increase.

The movement of substances in the skin is based on the distribution and diffusion action. The mask sheet, which can promote the movement of substances from the outside of the skin in a specific direction, promotes the distribution and diffusion of active ingredients into the skin, thereby increasing skin permeation promotion. (synergy) effect will further improve the epidermal absorption rate of the active ingredient.

In the mask pack for skin soothing according to another embodiment according to the present invention, a mask sheet, which is a substrate, is formed by being laminated in the order of a water absorbing layer, a water transition layer, and a water diffusion layer, and a water absorbing layer, a water transition layer, and a water diffusion layer. As the density increases and the hydrophilicity of the material and structure increases, the moisture moves from the inside of the mask pack to the outside and is discharged to the outside air through the moisture diffusion layer. As the moisture evaporates, the skin is given a cooling sensation, and the skin has a soothing effect. Therefore, according to the present invention, the mask pack structure itself may exhibit a skin soothing effect even if the mask pack does not include a component that gives a heat or cold feeling to the skin. Of course, in the case of applying to the skin by including a component that exhibits a skin soothing effect in the mask pack of the present invention can further enhance the skin soothing effect.

Preferably, the mask sheet of the present invention has a three-layer structure. When the mask sheet has a two-layer structure, moisture unidirectional permeability is maintained, but the time for the moisture to stay in the mask sheet itself is too short, that is, the sheet dries too quickly. This is because the active ingredient is less likely to be absorbed into the skin sufficiently and the time for showing the skin soothing effect is shortened.

The moisture content of the fiber in the standard state is called process moisture content, and natural fibers such as cotton (8.5%), rayon (11%), and wool (18.25%) have high hydrophilicity, so that the process moisture content is high, and polyethylene (0.0%), Chemical fibers such as polyester (0.4%), acrylic (1.5%), nylon (4.5%), and the like have low hydrophilicity and low process moisture content. However, even in the case of chemical fibers, hydrophilicity can be increased by introducing a hydrophilic group during spinning, and by adjusting the shape of the nozzle during spinning, it is possible to manufacture a shaped cross-section yarn such as a star or a triangular shape whose cross section is not circular. This can increase the hydrophilicity of the fibers.

Therefore, the fibers constituting each layer of the mask sheet of the present invention is not limited to the kind, but the relatively hydrophobic water absorbing layer is preferably made of polyethylene, a polyolefin-based fiber having a low process water content, and the relatively hydrophilic water diffusion layer is It is preferable that the process moisture content of the nylon, cotton, hydrophilicity-modified polyester and the like or a circular cross-section cross-sectional yarn, the water-transfer layer having a moderate degree of hydrophilicity is preferably a polyester circular or a cross-sectional cross-section yarn.

Hereinafter, described in detail by the accompanying drawings of the present invention.

1 shows a mask pack according to the present invention, which shows a mask pack 1 applied to an entire face, a nose pack 2 applied to a nose, and an eye pack 3 applied to an eye part according to an application site thereof. The mask sheet 10 of the pack 1 has an incision 11 and an opening 12 for easy close contact with the curved face shape. 3 shows a state diagram of use of the mask pack according to the present invention.

2 is a partial cross-sectional view of the mask sheet of the mask pack according to the present invention.

Figure 2 (a) shows a laminated structure of a mask pack having an active ingredient absorption promoting effect. The water absorption layer 7, the water transition layer 6, and the water diffusion layer 5 are formed from the outside of the mask sheet.

Since the water absorbing layer 7 is relatively hydrophobic and low density, and the water diffusing layer 5 is relatively hydrophilic and high density, such a structure causes spontaneous water movement from the outside to the inside of the mask sheet, thereby applying it to the skin. The amount of moisture that is added increases. As the moisture moves, active ingredients such as skin care ingredients contained in the mask sheet are moved together and applied to the skin.

The mask sheet, which can promote the movement of the substance in a specific direction, promotes the distribution and diffusion of the active ingredient into the skin, thereby increasing the epidermal absorption rate of the active ingredient by synergy effect of promoting the penetration of the active ingredient into the skin. It will be improved.

In the mask pack having the active ingredient absorption promoting effect, the skin adhesion layer may be further formed on the inner side of the moisture diffusion layer so that the mask sheet may be adhered to the skin without lifting. The skin adhesion layer may be formed of a natural pressure-sensitive adhesive or a synthetic pressure-sensitive adhesive, or a hydrogel. When the skin adhesion layer is formed to press the skin attachment surface in contact with the user's skin, the mask pack is attached to the user's skin without lifting due to adhesiveness.

The mask pack having the active ingredient absorption promoting effect may be prepared by applying a drug or cosmetic composition containing the active ingredient to the moisture absorbing layer, wherein the active ingredient is wrinkle improvement, whitening, moisturizing effect, soothing effect In addition, any one or more of raw materials having an effect of giving coolness to the skin, imparting a refreshing feeling to the skin, or imparting a cooling feeling to the skin may be included.

The drug or cosmetic composition containing the active ingredient is arbutin, vitamin C (ascorbic acid), MAP (magnesium ascorbyl phosphate), AA2G (ascorbyl acid 2) in addition to coenzyme Q10, albumin, green tea solution, collagen and hyaluronic acid, etc. -Whitening substance such as -glucoside, anti-wrinkle effect such as paeoniflorin, kinetin, auxin, peptide, alpha-hydroxy acid, etc. Substances, candelilla wax, alpha bisabolol, aloe vera, manjistar, gugal, pine needle extract, collagen extract, grape extract, quince extract, green tea extract, ginkgo extract, seaweed extract, lavender, chamomile, tea tree, lemon balm, It may include any one or more of the natural soothing ingredients having a soothing effect such as honey, peppermint, avocado oil, soybean oil.

After a certain time has elapsed while the mask pack having the active ingredient absorption promoting effect is attached to the skin, the active ingredient contained in the sheet penetrates deeply into the user's skin by the moisture flow promoting effect of the mask sheet. It will become effective and effective.

Figure 2 (b) shows a laminated structure of the mask pack having a skin soothing effect. The water absorption layer 7, the water transition layer 6, and the water diffusion layer 5 are formed from the inside of the mask sheet.

The moisture absorbing layer 7 is relatively hydrophobic and low density, and the water diffusion layer 5 is relatively hydrophilic and high density, so that the moisture of the skin is moved from the inside of the mask sheet to the outside due to this structure. It is emitted from the water diffusion layer into the outside air. The spontaneous release of moisture gives the skin a sense of heat, resulting in soothing and shrinking pores. A mask pack may be manufactured by including a cosmetic composition having an effect of soothing the skin by imparting a refreshing or cold feeling to the skin to the mask sheet having the above structure.

The cosmetic composition having the skin soothing effect includes candelilla wax, alpha bisabolol, aloe vera, manjistar, gugal, pine needle extract, collagen extract, grape extract, quince extract, green tea extract, ginkgo extract, seaweed extract, lavender, Any one or more of the soothing natural ingredients such as chamomile, tea tree, lemon balm, honey, peppermint, avocado oil, soybean oil may be included.

In the above skin care mask pack, the skin adhesion layer may be further formed on the inner side of the moisture absorption layer so that the mask sheet may be adhered to the skin without lifting. The skin adhesion layer may be formed of a natural pressure-sensitive adhesive or a synthetic pressure-sensitive adhesive, or a hydrogel. Figure 2 (c) shows a cross-sectional structure of the mask pack of the present invention in which a hydrogel layer is formed as a skin adhesion layer.

According to the present invention, the cosmetic active ingredient is applied to the mask sheet, so that the mask pack can be reused, and the active ingredient penetrates deep into the skin by the moisture unidirectional permeability sheet to exert a cosmetic effect and a therapeutic effect. It has the advantage that it can exert the soothing effect and cooling effect by rapidly evaporating moisture to the outside of the skin. In addition, the sheet having a direction to the moisture permeation of the present invention can be easily changed the direction of the water permeation by changing its laminated structure can be used for a variety of uses and can be applied to the skin of all parts of the body as well as the face.

Hereinafter, the present invention will be described in more detail with reference to examples and test examples, but the present invention is not limited to the following examples.

Example 1 Preparation of Mask Sheet

In the high-speed repier loom, a polyester release section yarn with 75 denier hydrophilic group (-OH) is injected into the water diffusion layer, a 75 denier circular polyethylene yarn is injected into the water absorption layer, and 75 denier polyester is used for the water transition layer. By supplying a sectional cross-section yarn, the moisture absorbing layer was woven so as to protrude outward from the water transition layer, so that the moisture absorbing layer, the water transition layer, and the water diffusion layer were laminated in this order. At this time, the water transition layer had a density twice the density (number of fibers per unit area) with respect to the water absorption layer and the water diffusion layer. This was cut to prepare a mask sheet for a mask pack of the type as shown in FIG.

< Test Example : Active ingredient skin absorption  Test>

Selection of Active Ingredients for Test

Solubility was confirmed by varying the formulation of the dissolution accelerator to select a drug-containing composition for application to a sheet having moisture unidirectional permeability according to the present invention. First, a dissolution accelerator (Tween 20, Tween 80) was mixed with a pH 7.4 phosphate buffered solution (phosphate buffered saline (PBS)) and then dissolved by adding hydrocortisone as an active ingredient.

Table 1 below is an experimental result of the dissolution state of the drug when the contents of the active ingredient hydrocortisone and the dissolution accelerator were changed.

[Table 1. Results of dissolution of drugs according to dissolution accelerator]

drug
(Hydrocortisone base) Solvent (PBS) Dissolution accelerator Dissolution state One 10mg 9500 ul 5% Tween 20 X 2 10mg 9000 ul 10% Tween 20 X 3 10mg 8500 ul 15% Tween 20 X 4 10mg 8000 ul 20% Tween 20 O 5 10mg 8000 ul 20% Tween 80 O 6 20mg 8000 ul 20% Tween 20 △ 7 20mg 8000 ul 20% Tween 80 △

X: not dissolved entirely, O: dissolved completely, Δ: partially dissolved

According to the results of Table 1, it can be seen that the drug is dissolved only when the amount of the dissolution accelerator is 20% or more, and it can be seen that the dissolution accelerator affects the dissolution of the drug. Sample 4 having the best dissolved state was selected to determine the effect of the moisture unidirectional permeable sheet.

Compatibility Test of Active Ingredients

Ascorbyl glucoside (AA2G) solution, which is a functional cosmetic ingredient that helps to whiten the skin, was added to the sheet having moisture unidirectional permeability according to the present invention to confirm compatibility.

Table 2 below shows the results of wetting and compatibility when the ascorbyl glucoside solution was added.

[Table 2. Compatibility Confirmation Result with Sheet]

Solution concentration
(Ascorbic Acid 2-Glucoside) Pack sheet Wettability Compatibility 8 1 mg / ml Water absorption layer O O 9 1 mg / ml Moisture diffusion layer O △

O: The solution is totally infiltrated and stable, △: The solution is partially infiltrated and metastable

According to the results of Table 2, it can be seen that the ascorbyl glucoside solution soaks well in both the absorbing layer and the diffusion layer of the moisture unidirectional permeable sheet. In the case of 9, since water was diffused, the compatibility was lower than that of 8.

<Test Example 1: skin absorption test of the active ingredient>

In order to measure the skin absorbance when the sample 4 selected in the test drug selection test was applied to the moisture unidirectional permeable sheet, a skin absorption test using hairless mouse skin was performed. The skin of a hairless mouse (species: CBA, female, 5 to 7 weeks old) was extracted immediately before the experiment, and the skin was fixed so that the stratum corneum layer faced up in the middle of a Franz-type diffusion cell. The moisture unidirectional permeable sheet prepared in Example 1 was positioned with the moisture absorbing layer facing up and the moisture diffusion layer facing down, and fixed with a clamp. Phosphate buffer solution (pH 7.4) was added to the receptor, and maintained at 37 ° C., and stirred constantly at a stirring speed of 600 rpm with a magnetic stirrer. After the sample 4 was placed in the donor, the solution of the receptor portion was collected at regular intervals, and the fresh buffer solution was replenished with the collected amount. Hydrocortisone concentration in the collected sample was measured by liquid chromatography (HPLC). The analysis conditions are as follows.

-> Analysis condition

Column: SHISEIDO C18 (5㎛, 4.6 X 250㎜) (HighChemical)

Mobile phase: acetonitrile / distilled water = 40/60

-Flow rate: 1.0 ml / min

Detector: 254nm UV

<Test Example 2>

Experiment in the same manner as in Test Example 1, but the moisture unidirectional permeable sheet prepared in Example 1 was placed in the opposite direction, that is, the water diffusion layer facing upwards and fixed with a clamp, the same experiment and analysis as in Test Example 1 It was.

<Comparative Test Example 1>

The experiment was conducted in the same manner as in Test Example 1, but the moisture unidirectional permeable sheet attached to the skin was not applied, and only the skin was fixed, and the test and analysis were performed in the same manner as in Test Example 1.

Table 3 shows the results of drug permeation, skin permeation rate and permeation delay time according to Test Example 1, Test Example 2, and Comparative Test Example 1 above.

Table 3. Results of Measurement of Skin Penetration Rate and Penetration Delay Time]

time Test Example 1 Test Example 2 Comparative Test Example 1 Average error Average error Average error 2 0.17 0.13 0.0 0.0 0.00 0.00 4 0.22 0.31 0.0 0.0 0.41 0.34 6 1.17 1.54 0.9 0.8 0.59 0.53 12 2.05 2.52 1.8 2.0 1.42 1.34 24 4.79 4.06 4.6 3.0 2.36 1.59 30 7.16 6.16 4.7 0.6 2.57 1.32 Flux (ug / cm2 / h) 0.24 0.14 0.2 0.1 0.10 0.00 Delay time (h) 5.1 2.4 4.4 2.0 6.22 2.34

As shown in Table 3 and FIG. 4, Test Example 1 and Example 2 to which the moisture unidirectional permeable sheet of the present invention is applied have a significantly higher concentration of hydrocortisone passing through the skin and a faster permeation rate than Comparative Test Example 1. As a result, it can be seen that the skin permeation effect of the drug is greatly improved when the moisture unidirectional permeable sheet is applied. In addition, in Test Example 1, the permeation concentration is increased by about 1.5 times or more compared to Test Example 2, and it can be seen that the stacking order of the moisture unidirectional permeable sheet also affects the permeation amount and permeation rate of the active ingredient.

< Test Example : Skin absorption test of cosmetic active ingredient>

<Test Example 3>

The moisture absorbing layer of the mask sheet was fixed upward and an ascorbyl glucoside solution (1 mg / ml) was applied to the water absorbing layer to measure skin absorption of the ascorbyl glucoside component. Experiment was carried out in the same manner as in Test Example 1.

Ascorbyl glucoside concentration in the collected sample was measured by liquid chromatography (HPLC). The analysis conditions are as follows.

-> Analysis condition

Column: SHISEIDO C18 (5㎛, 4.6 X 250㎜) (HighChemical)

Mobile phase: 0.02 M NaH ₂ PO ₄ solution

-Flow rate: 1.0 ml / min

Detector: 258nm UV

<Test Example 4>

The water diffusion layer of the mask sheet was fixed upward, and an ascorbyl glucoside solution (1 mg / ml) was applied to the water diffusion layer to measure skin absorption of the ascorbyl glucoside component. Experiment was carried out in the same manner as in Test Example 3.

As shown in FIG. 5, in the case of Test Example 4, permeation was not performed until 30 minutes after application, whereas in Test Example 3, it was found that the skin permeation effect of the active ingredient was greatly improved. As in the result of Test Example 1, it can be seen that the stacking order of the moisture unidirectional permeable sheet also affects the permeation rate and permeation rate of the active ingredient.

< Test Example : Skin soothing effect test >

Sheet itself  Cooling Effect Test

<Test Example 5>

In order to directly measure the cooling effect of the sheet having a direction to the water permeation of the present invention, the mask sheet having a direction to the water permeation prepared in Example 1 was placed with the water diffusion layer facing upwards and distilled water 10 mL (temperature : 21 ℃) was measured and the temperature change with time was measured. The part measured by thermometer was cut off from the outside using aluminum foil and insulation styrofoam to minimize the influence of the surrounding environment.

Comparative Test Example 2

After spraying 10mL of distilled water (temperature: 21 ° C) on a general nonwoven mask sheet having the same thickness as the mask sheet used in Test Example 5, the temperature change was measured over time, and measured by a thermometer to minimize the influence of the surrounding environment. The part is made of aluminum foil and insulated styrofoam to be isolated from the outside. The results are shown in Table 4 and FIG. 6.

[Table 4. Cooling Effect Measurement]

time Temperature (℃) Test Example 5 Comparative Test Example 2 0 minutes (before experiment) 26.5 26.5 0.5 minutes (30 seconds) 21.9 22.6 1 minute 21.4 22.2 2 minutes 21.2 21.5 3 minutes 20.8 21.3 5 minutes 20.8 21.2 10 minutes 20.6 21.1 20 minutes 20.3 20.8 30 minutes 20.3 20.8 1 hour 30 minutes 20.1 20.3 2 hours 19.5 20.0

As can be seen in Table 4 and FIG. 6, in the case of Test Example 5 using the sheet having a direction to moisture permeation compared to Comparative Test Example 2 it was found that the temperature cooling effect is excellent. In particular, in the case of Test Example 5 it was confirmed that the cooling effect is maintained at a lower temperature than Comparative Test Example 2 over time.

As soon as you spray distilled water (temperature: 21 ℃) on the mask sheet, the temperature of the mask sheet drops due to the temperature of the distilled water itself. In Comparative Example 2, it was confirmed that the time taken for about 21.5% cooling effect (20.8 ° C.) took 20 minutes or more compared to the temperature at 0 minutes (before the experiment), but in the case of Test Example 5, about 3 minutes After it was confirmed that the cooling effect of 21.5% appeared. This is because of the structure of the sheet to enhance the movement of moisture, and also confirmed that the surface temperature is lowered as the moisture is continuously evaporated.

Determination of skin soothing effect with distilled water

<Test Example 6>

Six men and women (age 30 ± 3) who are sensitive to irritation or are considered to be sensitive skin are selected and allowed to stand for 1 hour in constant temperature and humidity conditions (24 to 26 ℃, relative humidity of 40 to 50%). , The one-way permeable sheet of the present invention prepared in Example 1 was placed on one cheekbone area with the water diffusion layer facing upward and left for 20 minutes, and then the skin temperature was measured according to the time until the sheet was removed. Use the surface temperature gauge (SPOT THERMOMETER, MINOLTA CO., LTD. JAPAN) at the point of time before the pack application (0 minutes), 10 minutes, 20 minutes, and 10 minutes (30 minutes) after removal. Regions of interest (ROI) were set and the average temperature of the skin temperature in the ROI was analyzed to analyze the rate of temperature change over time.

Comparative Test Example 3

In Test Example 6, except that the nonwoven fabric sheet was placed on the other cheekbone area, the test was carried out in the same manner as in Test Example 6, and the average temperature of the skin temperature in the ROI was taken to analyze the temperature change rate over time.

The results are shown in Table 5 and FIG.

[Table 5. Result of measuring temperature change with time after applying mask pack sheet]

time Temperature (℃) Test Example 6 Comparative Test Example 3 Before sample application (0 minutes) 31.75 ± 0.07 32.15 ± 0.92 10 minutes 25.85 ± 0.64 26.45 ± 0.38 20 minutes 25.50 ± 0.42 26.40 ± 0.56 30 minutes 29.90 ± 0.42 30.25 ± 0.47

As can be seen in Table 5 and FIG. 7, it was found that in the case of Test Example 6 compared to Comparative Test Example 3, the skin cooling effect is excellent. In particular, even after removing the mask pack sheet, in the case of Test Example 6 it was confirmed that the cooling effect is maintained at a lower temperature than Comparative Test Example 3. This indicates that the sedation effect of the skin can be increased by controlling the movement of water as a result showing the same trend as the result of Table 4, which directly measured the cooling effect at room temperature using distilled water.

Example 2-3 Preparation of Cosmetic Composition Applied to the Mask Pack of the Present Invention

To the cosmetic composition of Example 2 and Example 3 was prepared in the composition of Table 6, the preparation method is as follows. Phase a in Table 6 is mixed to disperse and dissolve completely. After confirming complete dissolution, the b phase is measured, completely dissolved, and then charged into the a phase and stirred for 30 minutes. The c and d phases are added to the mixed solution so as to be completely uniformly dispersed.

[Table 6. Composition of Cosmetic Composition]

Ingredient Content (% by weight) Example 2 Example 3 a Distilled water 76.38 79.38 Sodium Polyacrylate 0.2 0.2 Polyvinyl alcohol 0.4 0.4 Sodium Hyaluronate 0.02 0.02 ethanol 4.5 4.5 b Polysorbate 0.3 0.3 Methyl paraben 0.1 0.1 Propylparaben 0.05 0.05 incense 0.02 0.02 1,3 propanediol 15.0 15.0 c Urea powder 0 2.0 Xylitol 0 1.0 d Lactic Acid 0.03 0.03

Test Example 7: Determination of skin soothing effect of cosmetic composition-containing mask pack

The cosmetic composition prepared in Example 2 and Example 3 was applied to the moisture unidirectional permeable sheet prepared in Example 1 and then tested in the same manner as in Test Example 6 and analyzed for the rate of temperature change over time. The results are shown in Table 7 and FIG. Similarly, measurement images were obtained using an IR camera (Thermogam, IR Korea) at the time point before the start of the pack application (0 minutes), 10 minutes, 20 minutes and 10 minutes (30 minutes) after removal. The taken IR camera measurement image is shown in FIG. 9.

[Table 7. Temperature change measurement result over time after applying mask pack sheet]

time Temperature (℃) Example 3 Example 2 Before sample application (0 minutes) 30.8 ± 1.13 30.85 ± 1.20 10 minutes 24.7 ± 1.98 24.5 ± 0.28 20 minutes 23.7 ± 0.71 23.35 ± 0.64 30 minutes 27.1 ± 1.70 27.3 ± 1.56

As a result of Table 7 and FIG. 8, it was confirmed that the temperature lowering effect of Example 2 and Example 3 according to the present invention in the skin temperature change appeared to be up to 24%, which is more efficient than the cooling effect by the cooling water. Could know. However, it was found that the case where the cosmetic composition of Example 3 containing urea powder and xylitol was applied was not much lower than the case where the cosmetic composition of Example 2 was applied. This result shows that even without xylitol and urea powder, which are expected to show cooling effect, sufficient cooling effect can be obtained by the movement of moisture in the cosmetics. Therefore, when used in large amounts on the skin, using a sheet that is directional to moisture permeation and does not contain ingredients that may cause severe irritation to the skin, it not only lowers the temperature of the skin but also imparts a refreshing feeling to the skin. Able to know.

In addition, looking at the image of the IR camera of Figure 9, it was confirmed that the cooling effect was higher on the right side of Example 2 applied than the left side of Example 3 applied, the skin temperature cooling effect lasted for about 20 minutes. From the above results, it was confirmed that the cosmetic composition according to the present invention is an effective method to maintain a low skin temperature continuously to feel the skin soothing effect substantially.

Example 4-5 Preparation of Hydrogel Mask Pack

A hydrogel mask pack having a hydrogel layer formed as a skin adhesion layer on the inner side of the mask sheet prepared in Example 1 was prepared as follows.

To the composition of the hydrogel type pack formulation was prepared in the composition of Table 8.

Table 8. Composition of Hydrogel Type Pack

Example 4 Example 5 Distilled water Distilled water glycerin glycerin Sodium hyaluronate Hydrolyzed Collagen Xanthan resin Locust bean resin Licorice extract Sodium Polyacrylate Hydrolyzed Collagen Polysorbate 80 Locust bean resin Dipotassium Glycylyzate Aloe leaf extract Himalayan Raspberry Root Extract Black tea extract Phenoxyethanol Sodium Polyacrylate Methyl paraben Polysorbate 80 Propylparaben Dipotassium Glycylyzate Disodium EDTA Himalayan Raspberry Root Extract incense Tartaric acid Vegetable collagen Phenoxyethanol Carrageenan Methyl paraben Purslane extract Propylparaben Disodium EDTA incense

Hereinafter, the preparation of the hydrogel mask pack having the composition of Example 4 will be described. While stirring in a 3 L heating vessel at room temperature, the mixture of glycerin and seratonia silicua gum is first mixed, and a solution of methyl paraben and propyl paraben is added thereto to make a mixed solution, and deionized water is added to the mixed solution to raise the temperature to 85 ° C. To prepare a gel solution. It was prepared by sequentially adding the remaining composition to the gel solution while maintaining a temperature of 85 ℃.

The hydrogel composition is prepared by changing the sheet prepared in Example 1 into a wick at 80 ° C. into a mask pack and cooling to room temperature to prepare a state-change hydrogel mask mask.

<Test Example 8: Determination of skin soothing effect of hydrogel type mask pack>

The hydrogel type mask packs prepared in Examples 4 and 5 were tested in the same manner as in Test Example 6, and the temperature change rate was analyzed over time. The results are shown in FIG.

As a result, the hydrogel composition of Example 5 according to the present invention in the skin temperature change was confirmed that the degree of temperature decrease after applying the pack is greater than that of the hydrogel composition of Example 4, but by the test example 7 It can be seen that there is no efficient cooling effect than the cooling effect.

<Test Example 9: Skin soothing effect panel test>

As described in Test Example 7 and Test Example 8, while the sedation effect was measured, a panel evaluation test for moisture and refreshing feelings were performed on the test subjects.

In order to find out the soothing effect and moisture when applying Examples 2, 4, 5 and 3 to the mask pack, the following experiment was conducted. The sedation effect experiment was performed twice each, and the results are shown in Table 9 and Table 10 according to the 5-point scale.

5 point scale

1: very bad, 2: bad, 3: normal, 4: good, 5: very good

[Table 9. Moisture Test Results Using Mask Pack]

Test Items Point size Example 3 Example 2 Example 4 Example 5

Skin moisture 5 9 10 3 8 4 One One 6 3 3 2 One 2 One 2 0 0 One 0 One 0 0 0 0 Total number of people 12 12 12 12 medium 4.58 4.75 3.92 4.58

[Table 10. Cooling test results using mask pack]

Test Items Point size Example 3 Example 2 Example 4 Example 5


Skin refreshment 5 10 11 0 7 4 One One 3 2 3 One 0 4 2 2 0 0 5 One One 0 0 0 0 Total number of people 12 12 12 12 medium 4.75 4.92 2.83 4.25

In the above table, the average value represents a value obtained by dividing the sum of each point value × number of judgments by the total number of participants.

When Example 2 was applied to the pack, the skin moisture and freshness test showed that the point scale average value was 4.75 and 4.92, respectively, and the best feeling was found. This is a result that can be seen that the effect is different depending on the formulation applied to the mask pack sheet.

The present invention relates to a mask pack that can be reused, and provides a technology for easily manufacturing a mask pack having various functions by changing the structure of the mask sheet, which is useful industrially and may also contribute to environmental protection.

1 is a plan view of a mask pack according to the present invention,

Figure 2 is a partial cross-sectional view of the mask pack according to the invention, (a) is a partial cross-sectional view of the mask pack of the present invention having an active ingredient absorption promoting effect, (b) is a partial cross-sectional view of the mask pack of the present invention having a skin soothing effect And, (c) shows a partial cross-sectional view of the hydrogel type mask pack of the present invention,

3 is a perspective view showing a state of use of the mask pack according to the present invention,

4 is an active ingredient skin permeation graph according to Test Examples 1 and 2 and Comparative Test Example 1 of the present invention,

5 is a graph showing the active ingredient skin permeation according to Test Examples 3 and 4 of the present invention,

6 is a graph illustrating a cooling effect of a mask pack sheet and a general nonwoven fabric according to Test Example 5 and Comparative Test Example 2 of the present invention with a temperature change,

7 is a graph illustrating the skin soothing effect of the test example 6 and the comparative test example 6 according to the present invention at a temperature change rate.

8 is a graph illustrating the skin soothing effect of the mask pack including the cosmetic compositions of Examples 2 and 3 of the present invention at a temperature change rate.

Figure 9 is an actual IR camera measurement image when the mask pack containing the cosmetic composition of Examples 2, 3 of the present invention applied to the face, (a) is immediately after the exercise (before the pack application), (b) is a pack 10 minutes after application, (c) is 20 minutes after pack application, (d) is IR camera measurement image 10 minutes after pack removal,

10 is a graph showing the cooling effect of the application of Examples 4 and 5 corresponding to the hydrogel type pack according to the present invention with temperature change.

<Description of Symbols for Main Parts of Drawings>

1: Mask Pack

2: nose pack

3: eye pack

10: moisture unidirectional permeable sheet

11: incision

12: opening part

5: moisture diffusion layer

6: moisture transition layer

7: water absorption layer

Claims (9)

In the mask pack applied to the skin, A three-layer structure in which a water absorbing layer (7), a water transition layer (6), and a water diffusion layer (5) made of a textile fabric are laminated in a relative order of the water absorption layer (7), the water transition layer (6), and the water diffusion layer (5). The hydrophilicity increases as the water absorbing layer, the water transition layer, and the water diffusion layer increases, and the density increases by 1.2 to 4 times as the water absorbing layer, the water transition layer, and the water diffusion layer increases the relative density and Mask pack comprising a mask sheet having a consistent orientation for the entire three-layer structure in water permeation due to spontaneous moisture transfer characteristics due to the difference in hydrophilicity. 2. The mask sheet according to claim 1, wherein the mask sheet is formed in the order of the moisture diffusion layer 5, the moisture transition layer 6, and the moisture absorption layer 7 therefrom, and the moisture diffusion layer 5, the moisture transition layer 6, Mask pack having an active ingredient absorption promoting effect, characterized in that the relative density and hydrophilicity decreases toward the water absorbing layer (7). The mask pack having an active ingredient absorption promoting effect according to claim 2, wherein a skin adhesion layer is further formed inside the moisture diffusion layer (5) of the mask sheet. 4. A mask pack having an active ingredient absorption promoting effect according to claim 2 or 3, wherein a drug or cosmetic composition containing an active ingredient is applied to the moisture absorbing layer (7) of the mask sheet. According to claim 4, wherein the drug or cosmetic composition containing the active ingredient is coenzyme Q10, albumin, green tea solution, collagen, hyaluronic acid; Substances having a whitening effect such as arbutin, vitamin C (ascorbic acid), magnesium ascorbyl phosphate (MAP), and ascorbyl acid 2-glucoside (AA2G); Substances having anti-wrinkle action, such as peoniflorin, kinetin, auxin, peptide, and alpha-hydroxy acid; Or candelilla wax, alpha bisabolol, aloe vera, manjistar, gugal, pine needle extract, collagen extract, grape extract, quince extract, green tea extract, ginkgo extract, seaweed extract, lavender, chamomile, tea tree, lemon balm, honey Mask pack having an active ingredient absorption promoting effect, characterized in that any one or more of the substances having a soothing effect, such as peppermint, avocado oil, soybean oil. According to claim 4, wherein the cosmetic composition containing the active ingredient is active, characterized in that applied in the form of a liquid, lotion, cream, gel, multi-lamella emulsion (MLE), or elastic liposome (elastic liposome) A mask pack with ingredient absorption promoting effect. 2. The mask sheet according to claim 1, wherein the mask sheet is formed in the order of the water absorbing layer 7, the water transition layer 6, and the water diffusion layer 5 from the inside thereof, and the water absorbing layer 7, the water transition layer 6, Mask pack having a skin soothing effect, characterized in that the relative density and hydrophilicity increases toward the water diffusion layer (5). [8] The mask pack of claim 7, wherein a skin adhesion layer is further formed inside the moisture absorbing layer of the mask sheet. The mask pack of claim 7 or 8, wherein a cosmetic composition having a skin soothing effect is applied to the mask sheet.

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