CN202283289U - Fixing tube and fixing device for neoplasms illumination of medical small mice - Google Patents
Fixing tube and fixing device for neoplasms illumination of medical small mice Download PDFInfo
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- CN202283289U CN202283289U CN2011204191245U CN201120419124U CN202283289U CN 202283289 U CN202283289 U CN 202283289U CN 2011204191245 U CN2011204191245 U CN 2011204191245U CN 201120419124 U CN201120419124 U CN 201120419124U CN 202283289 U CN202283289 U CN 202283289U
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- mouse tumor
- fixing
- stationary pipes
- irradiation
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Abstract
The utility model discloses a fixing tube for neoplasms illumination of small mice, which comprises a fixing tube body and a fixing plate, wherein the fixing tube body comprises a lateral wall and a base plate. The fixing plate is arranged at one end of an opening of the fixing tube body. The utility model further discloses a fixing device for the neoplasms illumination of medical small mice utilizing the fixing tube for the neoplasms illumination of the small mice, and the fixing device comprises one or more fixing tubes for the neoplasms illumination of the small mice and a platform. The fixing tube and the fixing device for the neoplasms illumination of the medical small mice are suitable for neoplasms illumination experiments for the small mice with neoplasms under skin of thighs, practical in function, simple in structure, low in cost and easy to popularize and can be recycled conveniently.
Description
Technical field
This utility model relates to a kind of radiation oncology zoopery fixture, relates to a kind of medical mouse tumor irradiation stationary pipes and fixture particularly.
Background technology
Mice is zooperies such as medical science, molecular biology laboratory animals commonly used.But because it belongs to living animal, its action has not self controllable property, therefore tends to experimental implementation is produced interference, even has the operator's that bite risk.In order to overcome the above problems, present existing solution has two, and the one, utilize the method for drug anesthesia to make it keep stable, the 2nd, utilize various little rat holders to limit its action.
Utilize the method for anesthesia that following problem is arranged: mice is different from the large-scale experiment animal, and volume is little, and body weight is light; The accuracy that narcotics uses is difficult to guarantee; Excessive meeting causes death, and the dose deficiency then can cause testing midway, and animal revives, and influences the accuracy of experiment process and experiment.Simultaneously, narcotics belongs to controlled drug, and deposit in its source, and use etc. all receives strict law and health care predetermined restricted, uses narcotics to have a lot of inconveniences in the experiment.
Detecting the influence of radiating transplantation tumor is radiation oncology; The test that radiobiology is common; Particularly mice thigh subcutaneous transplantation tumor is easy to carry out the tumor locus local irradiation, also is convenient to measurements such as gross tumor volume in addition; Therefore be radiation oncology, the easiest test that should go of radiobiology animal experiment.The suitable comparatively limitation of enclosing of the medium and small rat holder of prior art is used for experiments such as mouse tail vein blood sampling and injection, lumbar injection, intramuscular injection more, and the little rat holder of the irradiation experiment that is provided for mouse transplanting tumor is not arranged.Relate in the document of mouse transplanting tumor irradiation mice and adopt aspect such as which kind of device not relate at present to how fixedly.Usually, the mice irradiation time can be adopted the various fixed method, is to utilize a little easy device bands to fix mostly, such as centrifuge tube etc.
This utility model has solved the problem of the inapplicable mouse transplanting tumor irradiation of the little rat holder of above-mentioned prior art experiment; The medical mouse tumor irradiation fixture that has proposed a kind of mouse tumor irradiation stationary pipes and used this mouse tumor irradiation stationary pipes; This utility model can with clinac and the supporting use of Co-60 therapy apparatus; Have and be convenient to large batch of zooperal advantage; And this utility model function is practical and simple in structure, with low cost and be easy to popularization, conveniently is repeatedly used.
The utility model content
The utility model provides a kind of mouse tumor irradiation stationary pipes, comprising:
Fixedly body comprises sidewall and base plate, said fixedly body one end opening;
Fixing head;
Wherein, said fixing head is arranged on said opening one end of said fixedly body.
Wherein, said fixedly body is a cylinder.
Wherein, the sidewall of said fixedly body is provided with fixture.Said fixture can be the scalable intermediate plate.
Wherein, the sidewall of said fixedly body and base plate are provided with air-vent.
Wherein, the diameter of said fixedly body is 2.5-3.0cm, and fixedly the length of body is 7.0-9.0cm; The length of said fixing head is 5.0-7.5cm.
This utility model has also proposed a kind of medical mouse tumor irradiation fixture of using said mouse tumor irradiation stationary pipes, comprising:
One or more said mouse tumor irradiation stationary pipes;
Platform;
Wherein, said mouse tumor irradiation stationary pipes is arranged on four limits of said platform.
Wherein, the size of said platform is 45cm * 45cm * 0.5cm.
Wherein, said platform is provided with launched field and indicates line, and it indicates the coverage field of 30cm*30cm.
Wherein, said platform is provided with fixed mount, and said mouse tumor irradiation stationary pipes is fixed on the platform through said fixed mount.
The purpose of this utility model be to be used for when experiment irradiation fixedly the right thigh subcutaneous transplantation become the tumor mice, be the adaptation above-mentioned purpose, this experiment is novel to have following characteristics.
This utility model mouse tumor irradiation stationary pipes and medical mouse tumor irradiation fixture are suitable for clinac and Co-60 therapy apparatus.
This utility model mouse tumor irradiation stationary pipes and medical mouse tumor irradiation fixture are most of uses transparent lucite to constitute; Make mice to observe to the stationary pipes outside; And on stationary pipes, be designed with air-vent, therefore animal do not had constriction.In this utility model stationary pipes, process by slick lucite and plastics, avoid in the mice fixation procedure because collision causes damage with the mice contact site.
This utility model is arranged on the both sides scalable intermediate plate that is provided with on the stationary pipes sidewall and can fixes the mice trunk according to the mice body size, and its soma moves and head is invented a charge against thereby limit.Simultaneously, this utility model does not directly limit mouse head through avoiding adopting the head fixing means of being taked usually, has reduced mice constriction and uneasiness, and is more human.
The tail that this utility model is provided with mice reverses in the holder top, leans on matching and fixing such as adhesive tape, prevents the motion of its buttocks and afterbody and passes through hard material immobile phase ratio, and damage and stimulation probability also significantly reduce.
The tabular base plate that this utility model is connected with the stationary pipes bulk phase is used for fixing the right lower limb of stretched one-tenth tumor, with matching and fixing such as adhesive tape, effectively is embodied as the irradiation at tumor position, has avoided the irradiated risk in other positions of mice health simultaneously.
The lucite system platform that is provided with launched field sign line (indicating the coverage field of 30cm*30cm) that comprises in this utility model can satisfy the irradiation of 12 mices simultaneously; The applicable field of this utility model is extensive; Be applicable to that flatness and symmetry satisfy all clinacs or the Co-60 therapy apparatus of national standard; As long as the dosage in the launched field sign line institute sign scope of this utility model fixture platform is even, can supporting application this utility model.Plumbous door size through adjustment accelerator or Co-60 therapy apparatus can realize the adjustment for the irradiation field size.To general accelerator, the big I of its irradiation field is implemented in 1cm*1cm and in the scope of 40cm*40cm, adjusts.
Compare with mice fixture in the prior art, the utlity model has following characteristics:
This utility model is suitable for into tumor mouse tumor irradiation experiment.
This utility model is convenient to radiobiological studies.Because there are problems such as safety management in radiological installation, under the situation of no proprietary animal irradiation apparatus,, just can utilize this utility model to carry out zoopery as long as clinac or Co-60 therapy apparatus are arranged.
Utilize this utility model to save time conveniently, can shine simultaneously 12 mices for large-scale zoopery.
This utility model function is practical and simple in structure, be convenient to produce, and is with low cost, is easy to marketing, and this utility model all material can carry out sterilization treatment such as cleaning and sterilizing, conveniently is repeatedly used.
Description of drawings
Shown in Figure 1 is that this utility model mouse tumor shines the stationary pipes side view.
Shown in Figure 2 is that this utility model mouse tumor shines the stationary pipes front view.Wherein, Fig. 2 A, Fig. 2 B show the different structure of fixture respectively.
Shown in Figure 3 is that this utility model mouse tumor shines the stationary pipes vertical view.Wherein, Fig. 3 A, Fig. 3 B show the different structure of fixture respectively.
Shown in Figure 4 is the vertical view of the medical mouse tumor irradiation of this utility model fixture.
The specific embodiment
In conjunction with following specific embodiment and accompanying drawing, this utility model to be done further to specify, the protection content of this utility model is not limited to following examples.Under the spirit and scope that do not deviate from the utility model design, variation and advantage that those skilled in the art can expect all are included in this utility model, and are protection domain with the appending claims.
Like the mouse tumor irradiation stationary pipes 6 of Fig. 1, comprise fixedly body 1 and fixing head 2 to this utility model shown in Figure 3.Wherein, fixedly body 1 comprises sidewall 1-1 and base plate 1-2.Fixedly body 1 one ends are provided with base plate 1-2, other end opening.Fixing head 2 is tabular, and one of which is held row level with both hands and extended from the fixing sidewall 1-1 of body 1, and fixing head 2 is used for fixing stretched mice and becomes the right lower limb of tumor, cooperates the mice shank realization to fix with adhesive tape etc.Fixedly the diameter of body 1 is 3.0cm, and fixedly the length of body 1 is 9.0cm, and the length of fixing head 2 is 7.5cm.In this utility model, according to the size of mice individuality and the length of mice lower limb, fixedly the scope that is provided with of the diameter of body 1 is at 2.5-3.0cm, and fixedly the scope that is provided with of the length of body 1 is at 7.0-9.0cm, and the scope that is provided with of the length of fixing head 2 is at 5.0-7.5cm.
Be relatively set with two fixtures 3 on the sidewall 1-1, the position that fixture 3 is provided with is in the fixing middle strong point of body 1, highly is as the criterion with fixing mice trunk.The position that is provided with of fixture 3 can be according to mice trunk length adjustment.Shown in Fig. 2 B, fixing 3 is scalable intermediate plate 4, similar with screw, through the degree of depth of twisted change scalable intermediate plate 4 in fixing body 1.Individual hour when mice, be fixed through further twisted scalable intermediate plate 4.
Fixedly body 1 is a cylinder, and its sidewall 1-1 that is positioned over horizontal plane can be level.Can through be provided with in platform 7 bearings concavity fixedly body 1 be fixed on the platform 7.
Fixedly the sidewall 1-1 of body 1 is provided with air-vent 5 in the both sides of fixture 3, and two row's air-vents 5 are set on the base plate 1-2, and is as shown in Figure 2.
Shown in Fig. 2 A, Fig. 3 A, the width of fixing head 2 equals the width of the horizontal side wall 1-1 of connected fixedly body 1.Shown in Fig. 2 B, Fig. 3 B; The width of fixing head 2 also can be narrower than the fixedly width of body 1 horizontal side wall 1-1; In this utility model and linear accelerator and the matched medical mouse tumor irradiation fixture of Co-60 therapy apparatus; The width that fixing head 2 so is set helps practicing thrift its space occupied in launched field, thereby increases the mice quantity of shining simultaneously.
As shown in Figure 4, the medical mouse tumor irradiation fixture of this utility model comprises 12 mouse tumor irradiation stationary pipes 6 and platform 7.Mouse tumor irradiation stationary pipes 6 is one group with three, is arranged in parallel on a limit of platform 7.Platform 7 can hold 12 mouse tumor irradiation stationary pipes 6 simultaneously in this utility model, has both satisfied the irradiation field scope of clinac and Co-60 therapy apparatus, can carry out many group mouse tumor irradiation experiments simultaneously.Be arranged on the problem of fixing head 2 touchings of mutually perpendicular two mouse tumors irradiation stationary pipes 6 on four angles of platform 7 for solution; Can be arranged on 7 last times of platform mouse tumor being shone stationary pipes 6, select that fixing head 2 is short for example to be the long mouse tumor irradiation stationary pipes 6 of 5cm for use.
The size of the platform 7 of fixture is 45cm*45cm.The size of platform 7 is adapted to general accelerator and the supporting use of Co-60 therapy apparatus and is provided with.General existing accelerator passes through the plumbous door of adjustment and realizes the variation adjustment of its launched field size in 1cm*1cm arrives the scope of 40cm*40cm, and the size of the platform 7 that provides thus in this utility model is 45cm*45cm.
Platform 7 is provided with launched field and indicates line 8, and it indicates the coverage field of 30cm*30cm.Launched field indicates line 8, and to be adapted to the roentgenization scope of medical apparatus and instruments such as linear accelerator and Co-60 therapy apparatus set.Put in 7 last times of platform mouse tumor being shone stationary pipes 6,, fixing head 2 is placed in the launched field as operator's reference.
Platform 7 is provided with fixed mount 9, and mouse tumor irradiation stationary pipes 6 is shelved on the platform 7 through fixed mount 9.
Embodiment 1
The actual occupation mode of present embodiment explanation this utility model.
The subcutaneous one-tenth tumor of right thigh mice is driven fixedly body 1 of entering; Afterbody mentioned to reverse fix in the fixing sidewall 1-1 blended rubber band on body 1 top; Adjustment bilateral scalable intermediate plate 4 screw knobs adjustment distance; The mice trunk clamped it can't be turned one's head, will become the right lower limb of tumor to pull out then to extend to fixing head 2 that fixedly body 1 is connected on, ankle part is fixed with adhesive tape.According to the irradiation needs, will be placed on four limits of platform 7 through 12 mouse tumors irradiation stationary pipes 6 that above method fixes mice, place launched field to indicate in the scope that line 8 indicates fixing head 2 during placement, make that having only into the right lower limb of tumor places in the launched field.Then its integral body is placed and carry out the transplantation tumor irradiation under the medical accelerator of adjusting launched field and the Co-60 therapy apparatus head.After irradiation finishes, remove adhesive tape and loosen scalable intermediate plate 4, take out postradiation mice, utilize tote box that it is sent back to and raise the place.
Claims (10)
1. a mouse tumor irradiation stationary pipes is characterized in that, comprising:
Fixedly body (1) comprises sidewall (1-1) and base plate (1-2), said fixedly body (1) one end opening;
Fixing head (2);
Wherein, said fixing head (2) is arranged on said opening one end of said fixedly body (1).
2. mouse tumor irradiation stationary pipes as claimed in claim 1 is characterized in that said fixedly body (1) is a cylinder.
3. mouse tumor irradiation stationary pipes as claimed in claim 1 is characterized in that the sidewall (1-1) of said fixedly body (1) is provided with fixture (3).
4. mouse tumor irradiation stationary pipes as claimed in claim 1 is characterized in that the sidewall (1-1) and the base plate (1-2) of said fixedly body (1) are provided with air-vent (5).
5. mouse tumor irradiation stationary pipes as claimed in claim 1 is characterized in that the diameter of said fixedly body (1) is 2.5-3.0cm, and fixedly the length of body (1) is 7.0-9.0cm; The length of said fixing head (2) is 5.0-7.5cm.
6. mouse tumor irradiation stationary pipes as claimed in claim 3 is characterized in that said fixture (3) is scalable intermediate plate (4).
7. use the medical mouse tumor irradiation fixture of mouse tumor irradiation stationary pipes according to claim 1 for one kind, it is characterized in that, comprising:
One or more said mouse tumor irradiation stationary pipes (6);
Platform (7);
Wherein, said mouse tumor irradiation stationary pipes (6) is arranged on four limits of said platform (7).
8. medical mouse tumor irradiation fixture as claimed in claim 7 is characterized in that the size of said platform (7) is 45cm * 45cm * 0.5 cm.
9. medical mouse tumor irradiation fixture as claimed in claim 7 is characterized in that said platform (7) is provided with launched field and indicates line (8), and said launched field indicates the coverage field that line (8) indicates 30cm*30cm.
10. medical mouse tumor irradiation fixture as claimed in claim 7 is characterized in that said platform (7) is provided with fixed mount (9), and said mouse tumor irradiation stationary pipes (6) is fixed on the platform (7) through said fixed mount (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011204191245U CN202283289U (en) | 2011-10-28 | 2011-10-28 | Fixing tube and fixing device for neoplasms illumination of medical small mice |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011204191245U CN202283289U (en) | 2011-10-28 | 2011-10-28 | Fixing tube and fixing device for neoplasms illumination of medical small mice |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202283289U true CN202283289U (en) | 2012-06-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011204191245U Expired - Fee Related CN202283289U (en) | 2011-10-28 | 2011-10-28 | Fixing tube and fixing device for neoplasms illumination of medical small mice |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202283289U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103519916A (en) * | 2012-07-04 | 2014-01-22 | 云南中医学院第一附属医院 | Adjustable fixing device for experiment domestic rabbit |
| CN103768723A (en) * | 2012-10-22 | 2014-05-07 | 上海交通大学医学院附属第九人民医院 | Mouse lower-limb radioactivity osteoradionecrosis model construction device |
-
2011
- 2011-10-28 CN CN2011204191245U patent/CN202283289U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103519916A (en) * | 2012-07-04 | 2014-01-22 | 云南中医学院第一附属医院 | Adjustable fixing device for experiment domestic rabbit |
| CN103768723A (en) * | 2012-10-22 | 2014-05-07 | 上海交通大学医学院附属第九人民医院 | Mouse lower-limb radioactivity osteoradionecrosis model construction device |
| CN103768723B (en) * | 2012-10-22 | 2016-03-30 | 上海交通大学医学院附属第九人民医院 | Rat lower limb osteoradionecrosis model construction device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120627 Termination date: 20191028 |