CN202210089U - Detection test piece - Google Patents

Detection test piece Download PDF

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Publication number
CN202210089U
CN202210089U CN2011203622874U CN201120362287U CN202210089U CN 202210089 U CN202210089 U CN 202210089U CN 2011203622874 U CN2011203622874 U CN 2011203622874U CN 201120362287 U CN201120362287 U CN 201120362287U CN 202210089 U CN202210089 U CN 202210089U
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CN
China
Prior art keywords
insulation course
test piece
substrate
working electrode
reference electrode
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Expired - Fee Related
Application number
CN2011203622874U
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Chinese (zh)
Inventor
徐添财
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HOUMEIDE BIOLOGICAL SCI-TECH Co Ltd
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HOUMEIDE BIOLOGICAL SCI-TECH Co Ltd
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Priority to CN2011203622874U priority Critical patent/CN202210089U/en
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Publication of CN202210089U publication Critical patent/CN202210089U/en
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Abstract

The utility model discloses a detection test piece comprising at least two working electrodes, at least one substrate of reference electrode, a first insulation layer, a second insulation layer, at least two side openings and at least two detection slots, wherein the first insulation layer is arranged on the substrate and is provided with at least two gaps on two corresponding sides; the second insulation layer is arranged on the first insulation layer and is provided with middle holes overlapped with the multiple gap parts on the first insulation layer; and the at least two side openings and the at least two detection slots are formed by the clamping of the substrate, the first insulation layer and the second insulation layer. The detection test piece can be used for detecting a same detected body for multiple times according to using demands, and can be used for detecting the detected body and the background value of the detected body simultaneously, thereby reducing environment errors caused by using different test pieces; or the test piece can be used for conducting different detection projects so as to improve the practicability of the test piece in use.

Description

Detect test piece
Technical field
The utility model relates to a kind of detection test piece, especially in regard to a kind of detection test piece with plural number detection groove.
Background technology
The inspection that has many diseases all to need long term monitoring now or need carry out immediacy is judged; But detection method in the past needs corpse or other object for laboratory examination and chemical testing cultivation, processing, the reaction time of long period mostly, therefore tends to the time that prolongation obtains testing result; In recent years; Along with the development of biochip technology, various is that the product of guiding constantly arises at the historic moment with instant detection, for instance; Whether carry out subsequent medical or inspection step if can carry out preliminary screening with decision, just can avoid expending huge medical resource for special case.
Having many on the market now is the detection test piece of principle with galvanochemistry, please refer to shown in Figure 1, wherein on a substrate 7; Plating has the working electrode 71 and reference electrode 72 of conductive material, and on described these electrodes 71,72, is coated with ferment or the chemical substance that detects usefulness, then is provided with dielectric layers 8,9 on this substrate 7; And insulation course 8,9 is provided with the relative and partly overlapping breach 81,91 of direction; And with substrate 7 on working electrode 71 and the reference electrode 72 common detection zones that form, rely on the capillary principle, can be so that a corpse or other object for laboratory examination and chemical testing gets into detection zone; With ferment or the action of chemicals coated on working electrode 71 and the reference electrode 72; Produce potential difference (PD), and via passing current potential information back a pick-up unit with the lead that working electrode 71 links to each other with reference electrode 72, so that testing result is calculated.
Such method can make each detect test piece only can carry out one-time detection; If want to repeat repeated detection, just must use a plurality of detection test pieces, but so just can neglect the different test piece differences that produce in manufacture process that detect; And the error amount that testing result is produced; Cause testing result deviation to some extent sometimes, and such detection test piece also can't carry out the test of detection background value, all can disturb to some extent for the correctness and the degree of accuracy of testing result; In addition, also can't carry out the different detection project simultaneously.
Summary of the invention
The utility model is artificial to solve existing detection test piece in the correctness of testing result and the disappearance of degree of accuracy; It is the exploitation of being devoted to carry out the coherent detection test piece; Finally develop the utility model; It is simple in structure, and the multiple detection test piece that can provide repeated detection, disparity items or background value to measure simultaneously.
For realizing above-mentioned purpose, the technical scheme that the utility model adopts is:
A kind of detection test piece is characterized in that, comprises a substrate, first insulation course and one second insulation course, wherein:
Described substrate, it is provided with:
At least one reference electrode is arranged on the front end of this substrate;
At least two working electrodes are arranged at the outside of this at least one reference electrode respectively;
At least two work connecting portions are arranged at the rear end of this substrate, and are connected in this corresponding working electrode through lead respectively; And
At least one contrasts connecting portion, is arranged at the rear end of this substrate, and is connected in this reference electrode through lead;
Described first insulation course is covered on this substrate, and is provided with at least two breach at the front end that side relatively should the base version, and this working electrode and this reference electrode of order part are revealed in outside this first insulation course, to form at least two detection grooves; And
Described second insulation course; Be covered on this first insulation course, and these at least two breach are provided with a mesopore relatively, wherein; These at least two breach and this mesopore are overlapped, and are inserted and put by this substrate, this first insulation course and this second insulation course and form at least two lateral openings.
These at least two working electrodes comprise one first working electrode and one second working electrode, and this first working electrode and this second working electrode are set in parallel in the both sides of this reference electrode respectively.
Described this reference electrode that these detect in the groove is common or uses separately.
Also comprise a front end breach, this front end breach is arranged at the front end of this first insulation course and overlaps with this mesopore, is inserted and put by this substrate, this first insulation course and this second insulation course and forms a front opening and a front-end detection groove.
Include one the 3rd working electrode and a reference electrode in this detection groove.
These at least two working electrodes comprise one first working electrode, second working electrode, the 3rd working electrode and one the 4th working electrode, and this at least one reference electrode comprises first reference electrode, second reference electrode and one the 3rd reference electrode.
This first arranges a side that is arranged at this substrate front end with the 3rd working electrode in regular turn, and this second arranges the also parallel corresponding opposite side that this substrate front end is set with the 4th working electrode in regular turn.
This first reference electrode be arranged at this first and this second working electrode between, it is corresponding that this second reference electrode and the 3rd reference electrode are parallel to each other, and be arranged between the 3rd and the 4th working electrode.
This first insulation course is provided with four breach respectively at relative this substrate of side; Respectively this breach corresponds respectively to this first to fourth working electrode; Detect groove to form four, the centre of corresponding described these breach of this second insulation course is provided with this mesopore, wherein; This mesopore and described these barbed portion are overlapping, are inserted and put by this substrate, this first insulation course and this second insulation course and form four lateral openings.
Also comprise a front end breach, this front end breach is arranged at the front end of this first insulation course and overlaps with this mesopore, is inserted and put by this substrate, this first insulation course and this second insulation course and forms a front opening and a front-end detection groove.
Be coated with the detectable layer on this working electrode in this detection groove and this reference electrode.
This work connecting portion and this contrast connecting portion all are connected with a pick-up unit.
Compared with prior art, adopt the advantage that the utlity model has of technique scheme to be:
Rely on above-mentioned structure; A corpse or other object for laboratory examination and chemical testing to be detected can utilize capillarity moving toward corresponding detection concentrated flow by lateral openings, and reacts the generation potential difference (PD) at the detection groove, also can directly the direct point of a corpse or other object for laboratory examination and chemical testing be put in mesopore; And because of first insulation course is covered on this substrate; Stop and described these breach are formed, and then avoid detecting a corpse or other object for laboratory examination and chemical testing in the groove and flow mutually and cause and disturb or pollute, let testing result that accurate phenomenon takes place to lose.
In addition; When the detection test piece of use the utility model detected, required corpse or other object for laboratory examination and chemical testing volume was merely several microlitres, detected groove because be provided with plural number again; So can significantly reduce because use the environmental error that different test piece produced; The utlity model has the application mode of diversification what is more, as long as rely on adjustment to coat the detectable layer (like ferment or chemicals) on working electrode and the reference electrode, just can accomplish the different detection purpose.
Description of drawings
Fig. 1 is the three-dimensional exploded view of existing detection test piece;
Fig. 2 is the three-dimensional exploded view that the utility model detects test piece one embodiment;
Fig. 3 is the part three-dimensional assembly diagram that the utility model detects test piece one embodiment;
Fig. 4 is that the utility model detects stereographic map after the assembling of test piece one embodiment;
Fig. 5 is the three-dimensional exploded view that the utility model detects another embodiment of test piece;
Fig. 6 is the three-dimensional exploded view that the utility model detects the another embodiment of test piece.
Description of reference numerals: 1-substrate; 111-first working electrode; 112-second working electrode; 113-the 3rd working electrode; 114-the 4th working electrode; The 12-reference electrode; First reference electrode of 121-; 122-second reference electrode; 123-the 3rd reference electrode; The 13-lead; The 14-lead; The 151-first work connecting portion; The 152-second work connecting portion; The 153-connecting portion of working; The 154-connecting portion of working; 16-contrasts connecting portion; 161-contrasts connecting portion; 162-contrasts connecting portion; 163-contrasts connecting portion; 2-first insulation course; The 21-breach; 22-front end breach; 3-second insulation course; The 31-mesopore-; 40-detects groove; 41-detects groove; 42-detects groove; 43-detects groove; 44-front-end detection groove; 51-top opening; The 52-lateral openings; The 6-front opening; The 7-substrate; The 71-working electrode; The 72-reference electrode; The 8-insulation course; The 9-insulation course; The 81-breach; The 91-breach.
Embodiment
Below promptly the utility model is detected test piece and carry out detailed explanation.
Please refer to Fig. 2 to shown in Figure 4, the detection test piece of the utility model comprises a substrate 1, first insulation course 2 and one second insulation course 3.
Extremely shown in Figure 4 like Fig. 2; According to an embodiment of the utility model, substrate 1 is provided with a reference electrode 12, one first working electrode 111, one second working electrode 112, one first work connecting portion 151, the second work connecting portion 152 and a contrast connecting portion 16.Reference electrode 12 is arranged at the front end of this substrate 1, first working electrode 111 and 112 both sides that are set in parallel in reference electrode 12 respectively of second working electrode.The first work connecting portion 151 and 152 rear ends that are arranged at this substrate 1 of the second work connecting portion, and be connected with first working electrode 111 and second working electrode 112 through lead 13 respectively.Contrast connecting portion 16 also is arranged at the rear end of substrate 1, and connects reference electrode 12 through lead 14.
In this embodiment; First insulation course 2 is covered on this substrate 1; And side relatively the front end of this substrate 1 be provided with two breach 21; Respectively this breach 21 corresponds respectively to first working electrode 111 and second working electrode 112, so that the working electrode 111,112 and the reference electrode 12 of part are revealed in outside first insulation course 2, detects groove 40,41 to form two.Second insulation course 3 is covered on first insulation course 2; And relative two breach 21 are provided with a mesopore 31; Two breach 21 are overlapped to form two top openings 51 with mesopore 31, are inserted and put by substrate 1, first insulation course 2 and second insulation course 3 and form two lateral openings 52.
It should be noted that; Because first insulation course 2 covers on this substrate 1; Second insulation course 3 is covered on first insulation course 2; The thickness of first insulation course 2 can form a groove with lateral openings 52 respectively, and two side direction openings 52 are produced intercepts, and then forms two and independently detect groove 40,41.In this embodiment, each detects groove 40,41 shared single reference electrodes 12, and respectively has a working electrode 111,112.In other words, the detection groove 40,41 of the detection test piece of the utility model has two corpse or other object for laboratory examination and chemical testing inlets, and one of them corpse or other object for laboratory examination and chemical testing inlet is lateral openings 52, and another corpse or other object for laboratory examination and chemical testing inlet is breach 21 and mesopore 31 partly overlapping top openings 51.Respectively this detection groove has one group of detecting electrode (working electrode and reference electrode), and detecting electrode is made up of 111,112 and 12 of reference electrodes of at least two working electrodes, and reference electrode 12 can use (figure does not show) jointly or separately.
When using the detection test piece of the utility model; Mesopore 31 or lateral openings 52 are introduced a liquid corpse or other object for laboratory examination and chemical testing to be measured thus; This corpse or other object for laboratory examination and chemical testing to be measured capillarity just capable of using moves toward detecting groove 40,41; And because 2 pairs two breach of first insulation course 21 intercept, can make a corpse or other object for laboratory examination and chemical testing to be measured of introducing from one of them lateral openings 52 can't be circulated to another lateral openings 52, and make two detect 40,41 of grooves testing result can not produce the situation that interferes with each other.
Another aspect; Because the design of detection test piece lateral openings of the utility model 52 and mesopore 31; A liquid corpse or other object for laboratory examination and chemical testing to be measured from intake to the reduced distances that detects groove 40,41; And with capillarity increase transfer efficiency, because of the set-up mode of mesopore 31, its vent port that also can be used as when reacting uses simultaneously; Make the detection test piece of the utility model in addition under the air guide, can implement to detect a letting corpse or other object for laboratory examination and chemical testing to be measured flow easily at the state that does not need to be provided with separately air hole toward detecting groove 40,41.In view of the above; A corpse or other object for laboratory examination and chemical testing to be measured can be in detecting groove 40,41 and the directly generation effect and produce potential difference (PD) of reagent that is coated on first, second working electrode 111,112 and the reference electrode 12; This potential difference (PD) can be sent to and detects the external detection device that test piece links to each other via lead 13, lead 14, work connecting portion 151,152 and contrast connecting portion 16; For carrying out follow-up interpretation, and converse testing result.
Please refer to shown in Figure 5ly, Fig. 5 is the synoptic diagram of detection test piece second embodiment of the utility model, the quantity of extendible detection groove like this.In this embodiment, detect test piece and comprise one first working electrode 111, one second working electrode 112, one the 3rd working electrode 113, one the 4th working electrode 114, first reference electrode 121, second reference electrode 122 and one the 3rd reference electrode 123.Detect test piece and comprise four work connecting portions 151~154 in addition, and comprise three contrast connecting portions 161~163 corresponding to described these reference electrodes 121~123 corresponding to described these working electrodes 111~114.
Work connecting portion 151~154 is arranged at the rear end of substrate 1 with contrast connecting portion 161~163, and connects corresponding working electrode 111~114 and reference electrode 121~123 respectively through lead 13,14 respectively.In this embodiment, the first and the 3rd working electrode 111,113 is arranged a side that is arranged at substrate 1 front end in regular turn, and the second and the 4th working electrode 112,114 is arranged in regular turn, and parallel correspondence is arranged at the opposite side of substrate 1 front end.First reference electrode 121 is arranged at first and second working electrode 111, between 112, it is corresponding that second reference electrode 122 and the 3rd reference electrode 123 are parallel to each other, and be arranged at the 3rd and the 4th working electrode 113, between 114.
Similar the foregoing description also comprises one first insulation course 2 and one second insulation course 3 in the detection test piece of present embodiment.First insulation course 2 is covered on this substrate 1; And respectively at side relatively the front end of this substrate 1 be provided with four breach 21; Respectively this breach 21 corresponds respectively to first to fourth working electrode 111~114; So that the working electrode 111~114 of part is revealed in outside first insulation course 2 with reference electrode 121~123, detect groove 40~43 to form four.Second insulation course 3 is covered on first insulation course 2; And described relatively these breach 21 centre are provided with a mesopore 31; Described these breach 21 are overlapped to form four top openings 51 with mesopore 31, are inserted and put by substrate 1, first insulation course 2 and second insulation course 3 and form four lateral openings 52.
In addition; According to first to the two above-mentioned embodiment; Detect in the test piece in addition and can be further to be provided with a front end breach 22 foremost in first insulation course 2; This front end breach 22 is overlapped with mesopore 31, to form another top opening 51, is inserted and put by substrate 1, first insulation course 2 and second insulation course 3 and forms another front opening 6 and a front-end detection groove 44.In view of the above, a corpse or other object for laboratory examination and chemical testing to be measured can be similar to the mode of lateral openings 52 through front opening 6, flow into to detect the detectable layer effect on groove and reference electrode, the working electrode through the capillarity principle.
Please refer to shown in Figure 6ly, Fig. 6 is the 3rd embodiment of the detection test piece of the utility model.Similar in this embodiment and first embodiment; Maximum difference is to detect test piece and has first reference electrode 121, second reference electrode 122 and one the 3rd working electrode 113; First reference electrode 121 relative second reference electrode, 122 spaced and parallel are arranged at the front end on this substrate 1, and through be connected to corresponding contrast connecting portion 161,162 with lead 14; In addition, the 3rd working electrode 113 is arranged at substrate 1 foremost, and links through lead 13 the 3rd work connecting portion 153 corresponding with this.The 3rd working electrode 113 alternative with first working electrode 111 or the single reference electrode 121,122 of second working electrode 112 shared; In present embodiment; The 3rd working electrode 113 and first working electrode, 111 shared first reference electrodes 121; And combine above-mentioned front end breach 22 to form a front-end detection groove 44, and having one group of detecting electrode in this front-end detection groove 44, it comprises the 3rd working electrode 113 and first reference electrode 121.
Shown in Fig. 4 to 6 figure; The shape of the mesopore 31 of each embodiment can be quadrilateral or octagon; Yet the utility model technical field possesses common skill personage knows that the shape of mesopore 31 includes but not limited to quadrilateral or octagon; Also can be other polygons, ellipse or circular, is to supply to running through the use of second insulation course 3.
In sum, therefore the detection test piece of the utility model has possessed and can carry out the diversification operation to reach the different advantages that detect effects via structural design cleverly; For instance, under an enforcement state, detect test piece and can carry out repeated detection to a same corpse or other object for laboratory examination and chemical testing; With the confidence level of strengthening detecting; A same corpse or other object for laboratory examination and chemical testing can be splashed into by lateral openings, front opening or mesopore, so can significantly reduce when detecting various changes because of, to obtain comparatively accurate testing result.
Implement the appearance attitude in another; Detect test piece and keeping under one group of working electrode and the reference electrode (also being one of them detecting electrode), splash into the corpse or other object for laboratory examination and chemical testing of detection simultaneously, then can detect simultaneously a corpse or other object for laboratory examination and chemical testing and its background value by mesopore; Rely on the background value of eliminating detection to obtain more accurate testing result; And then converse the background value of detection, more accurate for detecting, and can avoid taking place influencing the situation of testing result because of the difference between test piece.
In another enforcement appearance attitude; Detecting test piece also can detect to the heterogeneity in the same corpse or other object for laboratory examination and chemical testing; Can a corpse or other object for laboratory examination and chemical testing to be measured be led to by mesopore and detect groove, or lead to the detection groove by lateral openings, front opening, this detectable layer can be different reaction ferment; Thereby can analytes different in the blood be detected, reach the effect of multiple detection simultaneously.
Therefore; The detection test piece of the utility model can be applicable to the measurement of special component in the biological corpse or other object for laboratory examination and chemical testing such as blood, urine, saliva for example; Rely on change to coat the detectable layer kind on the detecting electrode; Just can carry out instant biochemistry detection for for example compositions such as blood sugar, blood fat, cholesterol, uric acid, alcohol, triglyceride, ketoboidies, kreatinin, lactic acid or protoheme; And increase the instant degree of accuracy that detects and the correctness of testing result, more can adjust to increase the application that the utility model detects test piece because of the detection demand.
More than explanation is just illustrative as far as the utility model; And nonrestrictive, those of ordinary skills understand, under the situation of spirit that does not break away from claim and limited and scope; Can make many modifications, variation or equivalence, but all will fall within the protection domain of the utility model.

Claims (12)

1. one kind is detected test piece, it is characterized in that, comprises a substrate, first insulation course and one second insulation course, wherein:
Described substrate, it is provided with:
At least one reference electrode is arranged on the front end of this substrate;
At least two working electrodes are arranged at the outside of this at least one reference electrode respectively;
At least two work connecting portions are arranged at the rear end of this substrate, and are connected in this corresponding working electrode through lead respectively; And
At least one contrasts connecting portion, is arranged at the rear end of this substrate, and is connected in this reference electrode through lead;
Described first insulation course is covered on this substrate, and is provided with at least two breach at the front end that side relatively should the base version, and this working electrode and this reference electrode of order part are revealed in outside this first insulation course, to form at least two detection grooves; And
Described second insulation course; Be covered on this first insulation course, and these at least two breach are provided with a mesopore relatively, wherein; These at least two breach and this mesopore are overlapped, and are inserted and put by this substrate, this first insulation course and this second insulation course and form at least two lateral openings.
2. detection test piece according to claim 1; It is characterized in that: these at least two working electrodes comprise one first working electrode and one second working electrode, and this first working electrode and this second working electrode are set in parallel in the both sides of this reference electrode respectively.
3. detection test piece according to claim 2 is characterized in that: described this reference electrode that these detect in the groove is common or uses separately.
4. detection test piece according to claim 3; It is characterized in that: also comprise a front end breach; This front end breach is arranged at the front end of this first insulation course and overlaps with this mesopore, is inserted and put by this substrate, this first insulation course and this second insulation course and forms a front opening and a front-end detection groove.
5. detection test piece according to claim 4 is characterized in that: include one the 3rd working electrode and a reference electrode in this detection groove.
6. detection test piece according to claim 1; It is characterized in that: these at least two working electrodes comprise one first working electrode, second working electrode, the 3rd working electrode and one the 4th working electrode, and this at least one reference electrode comprises first reference electrode, second reference electrode and one the 3rd reference electrode.
7. detection test piece according to claim 6 is characterized in that: this first arranges a side that is arranged at this substrate front end with the 3rd working electrode in regular turn, and this second arranges the also parallel corresponding opposite side that this substrate front end is set with the 4th working electrode in regular turn.
8. detection test piece according to claim 7; It is characterized in that: this first reference electrode be arranged at this first and this second working electrode between; It is corresponding that this second reference electrode and the 3rd reference electrode are parallel to each other, and be arranged between the 3rd and the 4th working electrode.
9. detection test piece according to claim 8; It is characterized in that: this first insulation course is provided with four breach respectively at relative this substrate of side, and respectively this breach corresponds respectively to this first to fourth working electrode, detects grooves to form four; The centre of corresponding described these breach of this second insulation course is provided with this mesopore; Wherein, this mesopore and described these barbed portion are overlapping, are inserted and put by this substrate, this first insulation course and this second insulation course and form four lateral openings.
10. detection test piece according to claim 9; It is characterized in that: also comprise a front end breach; This front end breach is arranged at the front end of this first insulation course and overlaps with this mesopore, is inserted and put by this substrate, this first insulation course and this second insulation course and forms a front opening and a front-end detection groove.
11. detection test piece according to claim 1 is characterized in that: be coated with the detectable layer on this working electrode in this detection groove and this reference electrode.
12. detection test piece according to claim 1 is characterized in that: this work connecting portion and this contrast connecting portion all are connected with a pick-up unit.
CN2011203622874U 2011-09-26 2011-09-26 Detection test piece Expired - Fee Related CN202210089U (en)

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Application Number Priority Date Filing Date Title
CN2011203622874U CN202210089U (en) 2011-09-26 2011-09-26 Detection test piece

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Application Number Priority Date Filing Date Title
CN2011203622874U CN202210089U (en) 2011-09-26 2011-09-26 Detection test piece

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CN2011203622874U Expired - Fee Related CN202210089U (en) 2011-09-26 2011-09-26 Detection test piece

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108627613A (en) * 2017-03-24 2018-10-09 郑兆珉 Device and method for manufacturing test strip

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108627613A (en) * 2017-03-24 2018-10-09 郑兆珉 Device and method for manufacturing test strip
CN108627613B (en) * 2017-03-24 2020-10-13 郑兆珉 Device and method for manufacturing test strip

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20120502

Termination date: 20180926