CN202204794U - Noninvasive glucose monitoring system - Google Patents
Noninvasive glucose monitoring system Download PDFInfo
- Publication number
- CN202204794U CN202204794U CN2011202973089U CN201120297308U CN202204794U CN 202204794 U CN202204794 U CN 202204794U CN 2011202973089 U CN2011202973089 U CN 2011202973089U CN 201120297308 U CN201120297308 U CN 201120297308U CN 202204794 U CN202204794 U CN 202204794U
- Authority
- CN
- China
- Prior art keywords
- glucose
- blood glucose
- monitoring system
- saliva
- value
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The utility model discloses a noninvasive glucose monitoring system, which comprises a salivary glucose concentration acquiring device, a processing host and a remote monitoring center. The salivary glucose concentration acquiring device is used for collecting a saliva sample and acquiring physicochemical signals in the saliva sample. The processing host measures current glucose value according to the physicochemical signals, relates the glucose value to a plurality of glucose values of previous periods recorded in a personal glucose database in a storage unit so as to draw a curve of personal glucose. After a processor calls glucose data of corresponding periods in a healthy glucose database and draws a curve of glucose reference, the processing host displays the glucose value, the curve of personal glucose and the curve of glucose reference. The remote monitoring center receives, displays and stores the glucose valve sent by the processing host. The noninvasive glucose monitoring system is based on positive correlation between salivary glucose concentration and glucose concentration, starts from measuring salivary glucose concentration, and indirectly measures glucose concentration. Compared with existing instruments based on noninvasive glucose monitoring technology, the noninvasive glucose monitoring system has the advantages of convenience in operation, convenience to carry, high accuracy of measuring results, good stability of instrument and the like.
Description
Technical field
The utility model belongs to the blood sugar test technical field, relates in particular to a Woundless blood sugar monitoring system.
Background technology
(self-monitoring of blood glucose SMBG) is the international at present extensively diabetes management methods of approval to diabetic oneself blood sugar monitoring.Conventional blood sugar monitoring needs acupuncture to gather peripheral blood, and scientific and reasonable every day of 5-6 detection can add up every annual nearly 2000 times acupuncture wound of suffering from, and for this reason, has now the Woundless blood sugar monitoring technology is provided, and existing Woundless blood sugar monitoring technology mainly contains:
1. near-infrared spectrum technique.When with near infrared ray irradiation human body, with the irrelevant tissue of blood sugar, like skin, bone, muscle, water etc.; To absorb most of infrared ray; The reflection of remaining a small amount of representative blood sugar characteristic or absorption infrared ray are called blood sugar characteristic frequency spectrum signal, can be used to extract blood glucose value.The problem of this method is: blood sugar characteristic frequency spectrum signal often very a little less than, be difficult to measure; This signal is relevant with body temperature and body fluid components, and monitoring result is inaccurate, must proofread and correct.The U.S. one company once produced and used this technological instrument-Diasensor, and the bodily form is bigger, costs an arm and a leg, and can't make accurate detection to hypoglycaem ic condition, so still in constantly debugging and researching and developing.
2. reverse ion electrophoretic techniques.Subcutaneous interstitial fluid be a kind of composition near the extracellular fluid of blood, nutriments such as glucose need to arrive cell via subcutaneous interstitial fluid.The reverse ion electrophoretic techniques can make subcutaneous interstitial fluid ooze out skin on a small quantity, like this, just can not have wound and obtains the subcutaneous interstitial fluid sample, records blood glucose value.Gluco-watch is to use this technological moulding instrument, has obtained FDA approval listing, but its stability and hypoglycemic omission behaved always denounces.
3. RF impedance is technological.When electromagnetic wave irradiation skin, nonionic solable matters such as subcutaneous glucose can absorb certain electromagnetic wave, draw concentration of glucose through calculating absorption value.PENDRA was abroad once arranged, and pertinent instruments such as GLUCOBAND occur, but because of costing an arm and a leg, accuracy is on the low side and the market of fading out.
4. other is such as based on the temperature check method, nuclear magnetic resonance method, and subcutaneous implant electrode method, the instrument of the graceful rays method of thunder etc. is developed, Monitoring Data is inaccurate, the problem of stability of instrument difference but all exist.
In sum, existing instrument based on the Woundless blood sugar monitoring technology exists that complex operation, monitoring result error are big, the problem of stability of instrument difference.
The utility model content
The purpose of the utility model is to provide a Woundless blood sugar monitoring system, has to solve existing instrument based on the Woundless blood sugar monitoring technology that complex operation, monitoring result error are big, the problem of stability of instrument difference.
The utility model provides a kind of Woundless blood sugar monitoring system, has: gather saliva sample and obtain this
The saliva sugar concentration deriving means (101) of the physics and chemistry signal in the saliva sample; Connect saliva sugar concentration deriving means (101); Calculating current blood glucose value according to this physics and chemistry signal also interrelates a plurality of blood glucose values of the former period of individual blood glucose level data storehouse record in this blood glucose value and the storage unit; Draw individual blood glucose curve; Simultaneously processor calls the blood glucose level data of corresponding period in the healthy blood glucose level data storehouse, draws with reference to behind the blood glucose curve, shows blood glucose value, blood glucose curve and with reference to the processing host (102) of blood glucose curve; Through cable network or wireless network connection processing main frame (102), receive the blood glucose value of processing host (102) transmission and the remote monitoring center (103) that shows, stores.
Said processing host (102) can be through Internet connection with remote monitoring center (103).
Said processing host (102) also can be connected through mobile communications network with remote monitoring center (103).
Said saliva sugar concentration deriving means further has:
Be configured for gathering the sample collecting portion (1) of saliva sample by polyurethane foam;
Be filled with lactochrome adenylic acid complexing GDH, the saliva sample that is used to make sample collecting portion (1) to gather carries out the electrochemical reaction groove (2) of electrochemical reaction;
Be connected on the electrochemical reaction groove (2), be used for the electric signal transfer wire (3) of the conduction of current that produces in the electrochemical reaction groove (2) to the main frame;
Said sample collecting portion (1) is fixed on the electrochemical reaction groove (2); Said electrochemical reaction groove (2) outside is provided with insulation course (201);
Said processing host further comprises:
The physics and chemistry conversion of signals that said saliva sugar concentration deriving means is obtained is the signal processing unit of electric signal;
Connect signal processing unit, receive and handle electric signal that said signal processing unit sends to calculate the processor of current blood glucose value;
The connection processing device, be pre-stored with the patient individual blood glucose level data storehouse that has the blood sugar secure threshold, the storage unit of healthy blood glucose level data storehouse and diet database; And
The connection processing device, have the control and the display unit of input function.
The lactochrome adenylic acid complexing GDH of further, filling in the said electrochemical reaction groove (2) is wrapped on the glass nano microballoon.
Further, lactochrome adenylic acid complexing GDH in the said electrochemical reaction groove (2) or the glass nano microballoon that is enclosed with lactochrome adenylic acid complexing GDH are dissolved in the phosphate-buffered saline damping fluid of pH value 7.4.
Further, also comprise and be used to monitor the threshold alerts unit (4) whether saliva that sample collecting portion (1) gathers reaches collection capacity; Said threshold alerts unit (4) comprising: be set in sample collecting portion (1) on every side, the humidity sensor (401) that the humidity of sample collecting portion (1) is detected;
Connect humidity sensor (401), the detected humidity value of humidity sensor (401) is compared with preset threshold, after humidity value reaches setting threshold, send the single-chip microcomputer (402) of alerting signal;
Connect single-chip microcomputer (402), the alerting signal that single-chip microcomputer (402) sends is carried out corresponding alarm unit (403);
Be connected on the loop that humidity sensor (401), single-chip microcomputer (402) and alarm unit (403) constitute, to the unlatching of circuit or close the switch of controlling (404).
Further also have: the alarm unit of connection processing device (9); Be set with the normal range threshold value of comprehensive glycemic index in the said individual blood glucose level data storehouse; When processor (7) detects said glycemic index and exceeds threshold value; Go up display alarm information at display unit (8), control alarm unit (9) simultaneously and report to the police.
Further also have the stationary installation of fixing saliva sugar concentration deriving means (101) and processing host (102), this stationary installation is an elastoplast, and the joint of this bandage is provided with velcro.
The Woundless blood sugar monitoring system that the utility model provides is based on the positive correlation of saliva sugar concentration and blood sugar concentration; Start with from measuring saliva sugar concentration; The indirect determination blood sugar concentration; Existing for existing instrument based on the Woundless blood sugar monitoring technology, have easy and simple to handle, be easy to carry, advantage such as measurement result degree of accuracy height and instrument stabilizer are good.
Description of drawings
Fig. 1 is the structural drawing of the Woundless blood sugar monitoring system that provides of the utility model;
Fig. 2 is the structural drawing of saliva sugar concentration deriving means among Fig. 1;
Fig. 3 is the further structural drawing of saliva sugar concentration deriving means among Fig. 1.
Embodiment
For the purpose, technical scheme and the advantage that make the utility model is clearer,, the utility model is further elaborated below in conjunction with accompanying drawing and embodiment.Should be appreciated that specific embodiment described herein only in order to explanation the utility model, and be not used in qualification the utility model.
As shown in Figure 1, the Woundless blood sugar monitoring system that the utility model provides comprises: gather saliva sample and obtain the saliva sugar concentration deriving means 101 of the physics and chemistry signal in this saliva sample; Connect saliva sugar concentration deriving means 101; Calculating current blood glucose value according to this physics and chemistry signal also interrelates a plurality of blood glucose values of the former period of individual blood glucose level data storehouse record in this blood glucose value and the storage unit; Draw individual blood glucose curve; Simultaneously processor calls the blood glucose level data of corresponding period in the healthy blood glucose level data storehouse, draws with reference to behind the blood glucose curve, shows blood glucose value, blood glucose curve and with reference to the processing host 102 of blood glucose curve; Through cable network or wireless network connection processing main frame 102, receive the blood glucose value of processing host 102 transmissions and the remote monitoring center 103 that shows, stores.
Cable network wherein can be the internet, and wireless network wherein can be mobile communications network or other electric communication network, and this mobile communications network is preferably GPRS network.
In addition, this system also comprises the stationary installation of fixing saliva sugar concentration deriving means 101 and processing host 102, and this stationary installation is an elastoplast, and the joint of this bandage is provided with velcro.
As shown in Figure 2, saliva sugar concentration deriving means 101 comprises: the sample collecting portion 1 that is configured for gathering saliva sample by polyurethane foam; Be filled with lactochrome adenylic acid complexing GDH, the saliva sample that is used to make sample collecting portion 1 to gather carries out the electrochemical reaction groove 2 of electrochemical reaction; Be connected on the electrochemical reaction groove 2, be used for the electric signal transfer wire 3 of the conduction of current that produce in the electrochemical reaction groove 2 to the main frame; Sample collecting portion 1 is fixed on the electrochemical reaction groove 2; Electrochemical reaction groove 2 outsides are provided with insulation course 201.
The lactochrome adenylic acid complexing GDH of wherein, filling in the electrochemical reaction groove 2 is wrapped on the glass nano microballoon.
Wherein, lactochrome adenylic acid complexing GDH in the electrochemical reaction groove 2 or the glass nano microballoon that is enclosed with lactochrome adenylic acid complexing GDH are dissolved in the phosphate-buffered saline damping fluid of pH value 7.4.
In conjunction with Fig. 2 and shown in Figure 3, saliva sugar concentration deriving means 101 also comprises and is used to monitor the threshold alerts unit 4 whether saliva that sample collecting portion 1 gathers reaches collection capacity; Said threshold alerts unit 4 comprises: be set in around the sample collecting portion 1 humidity sensor 401 that the humidity of sample collecting portion 1 is detected; Connect humidity sensor 401, humidity sensor 401 detected humidity values are compared with preset threshold, after humidity value reaches setting threshold, send the single-chip microcomputer 402 of alerting signal; Connect single-chip microcomputer 402, the alerting signal that single-chip microcomputer 402 sends is carried out corresponding alarm unit 403; Be connected on the loop that humidity sensor 401, single-chip microcomputer 402 and alarm unit 403 constitute, to the unlatching of circuit or close the switch of controlling 404.
Further, processing host 102 comprises: the physics and chemistry conversion of signals that saliva sugar concentration deriving means 101 is obtained is the signal processing unit of electric signal; Reception is also handled the electric signal that said signal processing unit sends, and calculates the processor of current blood glucose value; Be pre-stored with the patient individual blood glucose level data storehouse that has the blood sugar secure threshold, the storage unit of healthy blood glucose level data storehouse and diet database; And the display unit that has control and input function; The blood glucose value that processor will be handled gained is presented on the display unit; A plurality of blood glucose values of the former period of individual blood glucose level data storehouse record in this blood glucose value and the storage unit are interrelated, draw individual blood glucose curve, processor calls the blood glucose level data of corresponding period in the healthy blood glucose level data storehouse simultaneously; Drafting is with reference to blood glucose curve; With said blood glucose value, blood glucose curve and be presented on the display unit, the correlation parameter of each database in the updated stored unit simultaneously with reference to blood glucose curve; In display unit, import food variety; Feed quantity and eating time; Processor calculates total sugar content of feed according to the contained sugar of the varieties of food items of putting down in writing in the diet database, and according to the blood glucose value that obtains in meal time and the above-mentioned steps; Section was done and was relatively drawn comprehensive glycemic index detection time, and this index is presented on the display unit;
Further; Processing host 102 also comprises: the alarm unit of connection processing device; Be set with the normal range threshold value of comprehensive glycemic index in individual's blood glucose level data storehouse; When processor detected said glycemic index and exceeds threshold value, display alarm information on display unit was controlled alarm unit simultaneously and is reported to the police.
The Woundless blood sugar monitoring system that the utility model provides is based on the positive correlation of saliva sugar concentration and blood sugar concentration; Start with from measuring saliva sugar concentration; The indirect determination blood sugar concentration; Existing for existing instrument based on the Woundless blood sugar monitoring technology, have easy and simple to handle, be easy to carry, advantage such as measurement result degree of accuracy height and instrument stabilizer are good.
The above; Be merely the preferable embodiment of the utility model; But the protection domain of the utility model is not limited thereto; Any technician who is familiar with the present technique field is equal to replacement or changes according to the technical scheme of the utility model and utility model design thereof in the technical scope that the utility model discloses, and all should be encompassed within the protection domain of the utility model.
Claims (9)
1. Woundless blood sugar monitoring system is characterized in that having:
Gather saliva sample and obtain the saliva sugar concentration deriving means (101) of the physics and chemistry signal in this saliva sample;
Connect saliva sugar concentration deriving means (101); Calculating current blood glucose value according to this physics and chemistry signal also interrelates a plurality of blood glucose values of the former period of individual blood glucose level data storehouse record in this blood glucose value and the storage unit; Draw individual blood glucose curve; Simultaneously processor calls the blood glucose level data of corresponding period in the healthy blood glucose level data storehouse, draws with reference to behind the blood glucose curve, shows blood glucose value, blood glucose curve and with reference to the processing host (102) of blood glucose curve;
Through cable network or wireless network connection processing main frame (102), receive the blood glucose value of processing host (102) transmission and the remote monitoring center (103) that shows, stores.
2. Woundless blood sugar monitoring system as claimed in claim 1 is characterized in that said processing host (102) and remote monitoring center (103) are through Internet connection.
3. Woundless blood sugar monitoring system as claimed in claim 1 is characterized in that said processing host (102) is connected through mobile communications network with remote monitoring center (103).
4. Woundless blood sugar monitoring system as claimed in claim 1 is characterized in that said saliva sugar concentration deriving means has:
Be configured for gathering the sample collecting portion (1) of saliva sample by polyurethane foam;
Be filled with lactochrome adenylic acid complexing GDH, the saliva sample that is used to make sample collecting portion (1) to gather carries out the electrochemical reaction groove (2) of electrochemical reaction;
Be connected on the electrochemical reaction groove (2), be used for the electric signal transfer wire (3) of the conduction of current that produces in the electrochemical reaction groove (2) to the main frame;
Said sample collecting portion (1) is fixed on the electrochemical reaction groove (2); Said electrochemical reaction groove (2) outside is provided with insulation course (201);
Said processing host comprises:
The physics and chemistry conversion of signals that said saliva sugar concentration deriving means is obtained is the signal processing unit of electric signal;
Connect signal processing unit, receive and handle electric signal that said signal processing unit sends to calculate the processor of current blood glucose value;
The connection processing device, be pre-stored with the patient individual blood glucose level data storehouse that has the blood sugar secure threshold, the storage unit of healthy blood glucose level data storehouse and diet database; And
The connection processing device, have the control and the display unit of input function.
5. Woundless blood sugar monitoring system as claimed in claim 4 is characterized in that the lactochrome adenylic acid complexing GDH of filling in the said electrochemical reaction groove (2) is wrapped on the glass nano microballoon.
6. like claim 4 or 5 described Woundless blood sugar monitoring systems, the glass nano microballoon that it is characterized in that the lactochrome adenylic acid complexing GDH in the said electrochemical reaction groove (2) or be enclosed with lactochrome adenylic acid complexing GDH is dissolved in the phosphate-buffered saline damping fluid of pH value 7.4.
7. Woundless blood sugar monitoring system as claimed in claim 4 is characterized in that also comprising whether the saliva of monitoring sample collecting portion (1) collection reaches the threshold alerts unit (4) of collection capacity; Said threshold alerts unit (4) comprising: be set in sample collecting portion (1) on every side, the humidity sensor (401) that the humidity of sample collecting portion (1) is detected;
Connect humidity sensor (401), the detected humidity value of humidity sensor (401) is compared with preset threshold, after humidity value reaches setting threshold, send the single-chip microcomputer (402) of alerting signal;
Connect single-chip microcomputer (402), the alerting signal that single-chip microcomputer (402) sends is carried out corresponding alarm unit (403);
Be connected on the loop that humidity sensor (401), single-chip microcomputer (402) and alarm unit (403) constitute, to the unlatching of circuit or close the switch of controlling (404).
8. Woundless blood sugar monitoring system as claimed in claim 4; It is characterized in that also having: the alarm unit of connection processing device (9); Be set with the normal range threshold value of comprehensive glycemic index in individual's blood glucose level data storehouse; When processor (7) detects said glycemic index and exceeds threshold value, go up display alarm information at display unit (8), control alarm unit (9) simultaneously and report to the police.
9. Woundless blood sugar monitoring system as claimed in claim 4 is characterized in that also having the stationary installation of fixing saliva sugar concentration deriving means (101) and processing host (102), and this stationary installation is an elastoplast, and the joint of this bandage is provided with velcro.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011202973089U CN202204794U (en) | 2011-08-16 | 2011-08-16 | Noninvasive glucose monitoring system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011202973089U CN202204794U (en) | 2011-08-16 | 2011-08-16 | Noninvasive glucose monitoring system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202204794U true CN202204794U (en) | 2012-04-25 |
Family
ID=45968912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011202973089U Expired - Fee Related CN202204794U (en) | 2011-08-16 | 2011-08-16 | Noninvasive glucose monitoring system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202204794U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102323310A (en) * | 2011-08-16 | 2012-01-18 | 苏州悦安医疗电子有限公司 | Noninvasive blood sugar monitoring system |
| CN103499621A (en) * | 2013-10-22 | 2014-01-08 | 文加斌 | Noninvasive blood glucose monitor |
-
2011
- 2011-08-16 CN CN2011202973089U patent/CN202204794U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102323310A (en) * | 2011-08-16 | 2012-01-18 | 苏州悦安医疗电子有限公司 | Noninvasive blood sugar monitoring system |
| CN103499621A (en) * | 2013-10-22 | 2014-01-08 | 文加斌 | Noninvasive blood glucose monitor |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102323310B (en) | Noninvasive blood sugar monitoring system | |
| US11600384B2 (en) | Systems and methods for managing glycemic variability | |
| CN101785701B (en) | The device of information processing, method, equipment and reagent carrier | |
| CN102462494A (en) | Novel intelligent electrocardiogram test healthcare apparatus | |
| WO2010077330A1 (en) | Method and/or system for estimating glycation of hemoglobin | |
| CN103892796A (en) | Wrist-mounted sleep monitoring system | |
| CN110522430A (en) | A kind of intelligent cardiac blood pressure instrument | |
| WO2021082259A1 (en) | Ecg electrocardiographic measurement mode switching method and apparatus, and wearable device and storage medium | |
| CN103499621A (en) | Noninvasive blood glucose monitor | |
| CN202075262U (en) | Wireless multifunctional continuous glucose monitoring system | |
| CN202204794U (en) | Noninvasive glucose monitoring system | |
| CN203885485U (en) | Multifunctional health detector | |
| CN202305465U (en) | Saliva glucose concentration acquisition device | |
| Cai et al. | Continuous glucose monitoring system based on smart phone | |
| CN205038221U (en) | Domestic noninvasive blood glucose sensing and physiotherapy device and system | |
| CN201453280U (en) | Mobile communication terminal | |
| CN202393731U (en) | Portable non-invasive blood glucose monitor | |
| CN102384931B (en) | Salivary glucose concentration acquiring device | |
| CN102512179A (en) | Non-destructive detector for human blood sugar | |
| CN205107649U (en) | Cloud health supervision system of traditional chinese medical science health control cloud platform family | |
| CN111603151B (en) | Noninvasive blood component detection method and system based on time-frequency combined analysis | |
| CN101762707A (en) | Mobile blood sugar detection method and system | |
| CN204318765U (en) | A kind of infrared spectrum technology non-invasive blood-sugar detecting instrument | |
| CN103876749A (en) | Built-in spectroscopy rapid blood glucose detection system | |
| CN206804658U (en) | Blue-tooth intelligence blood glucose meter |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: ZHANG WEIJIE Free format text: FORMER OWNER: SUZHOU YUEAN MEDICAL ELECTRONICS CO., LTD. Effective date: 20121024 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 215300 SUZHOU, JIANGSU PROVINCE TO: 116023 DALIAN, LIAONING PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20121024 Address after: 116023 No. 720, Huangpu Road, hi tech park, Liaoning, Dalian Patentee after: Zhang Weijie Address before: Suzhou City, Jiangsu province 215300 Kunshan Development Zone Road No. 179 207 chapter Patentee before: Suzhou Yuean Medical Electronics Co.,Ltd. |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120425 Termination date: 20150816 |
|
| EXPY | Termination of patent right or utility model |