CN202133580U - Heating mechanism for fully automatic glycosylated hemoglobin analyzer - Google Patents
Heating mechanism for fully automatic glycosylated hemoglobin analyzer Download PDFInfo
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- CN202133580U CN202133580U CN201120221213U CN201120221213U CN202133580U CN 202133580 U CN202133580 U CN 202133580U CN 201120221213 U CN201120221213 U CN 201120221213U CN 201120221213 U CN201120221213 U CN 201120221213U CN 202133580 U CN202133580 U CN 202133580U
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- pipeline
- haemolysis
- mixing pit
- heating
- soaking piece
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Abstract
The utility model discloses a heating mechanism for a fully automatic glycosylated hemoglobin analyzer, which comprises a hemolysis mixing pool. A metal soaking block with an electric heater is arranged inside the glycosylated hemoglobin analyzer, and the electric heater is installed outside the hemolysis mixing pool or a pipeline.
Description
Technical field
The utility model relates to the glycosylated hemoglobin analyser.Especially a kind of heating arrangements that is used for full-automatic saccharification hemoglobin analyser.
Background technology
During existing various glycosylated hemoglobin analyser testing human blood sample; If the blood sample of drawing is heated to 45-60 ℃ when mixing haemolysis reagent; Help to accelerate haemolysis speed, and remove the labile element in the blood, can improve precision of test result.When preparing analyzing samples; Use one to have the charger of inhaling appearance and the haemolysis reagent that heats,, be ejected into rapidly in the micro blood sample of absorption the haemolysis reagent that is heated to predetermined temperature; The haemolysis speed of blood sample is very fast, and accuracy that this sample is measured and repeatability are than higher.But this heating means need operating personnel in the instrument outside sample to be carried out one by one, are not suitable on full automatic analytical instrument, using.
Summary of the invention
The purpose of the utility model is to provide a kind of heating arrangements that is used for full-automatic saccharification hemoglobin analyser, lets heating and sampling carry out automatically.
The utility model is to realize through following technical scheme:
A kind of heating arrangements that is used for full-automatic saccharification hemoglobin analyser comprises the haemolysis mixing pit, and the metal soaking piece that has electric heater is located at the inside of glycosylated hemoglobin analyser, and electrical heating mechanism is installed in outside the outer or pipeline of haemolysis mixing pit.
Further, metal soaking piece and said haemolysis mixing pit tight connecting, haemolysis mixing pit are that cylindrical shape or upper end are the shape of cone for the right cylinder lower end.For the ease of observing sample introduction and the situation that adds haemolysis reagent, the haemolysis mixing pit generally adopts transparent material making such as organic glass, and coefficient of heat conductivity is low, and the sample firing rate is slower.Said metal soaking piece is provided with haemolysis pond observation panel, is provided with the LED lamp.
Another kind of scheme, metal soaking piece and said pipeline tight connecting, heated pipeline are the shapes that spirality or U word rotary type are gradually opened in cylindric spirality, plane.On metal soaking piece, be provided with the pipe-line tank of inserting pipeline, and with the slit of heat-conducting glue fill pipe.Haemolysis reagent in the heating pipe line makes the haemolysis reagent of heat mix with blood sample, can reach to separate heating and the purpose of diluting the lysed blood sample rapidly.
Description of drawings
Fig. 1, heating of haemolysis mixing pit and pipeline synoptic diagram;
Fig. 2, haemolysis mixing pit heating arrangement synoptic diagram;
Fig. 3, haemolysis mixing pit heating arrangement cut-open view;
Fig. 4: pipeline heating and pipeline synoptic diagram;
Fig. 5: plane pipeline heating and structural representation;
Fig. 6: plane pipeline heating and texture edge synoptic diagram;
Fig. 7: another heating of plane pipeline and structural representation;
Fig. 8: plane pipeline another heating and texture edge synoptic diagram;
Fig. 9: cylindric spiral pipeline heating and structure schematic top plan view;
Figure 10: cylindric spiral pipeline heating and structural representation.
Wherein:
1---sampling probe, 2---the sample behind the adding reagent, 3---haemolysis mixing pit, 4---having the metal soaking piece of electric heater, 5---pipeline; 6---pipeline, 7---solenoid valve, 8---solenoid valve, 9---pipeline, 10---pipeline; 12---pipeline, 13---pipeline, 14---pipeline, 15---gas outlet, 16---the pipeline nipple; 17---film sheet electric heater pressing plate, 18---heater holder, 19---haemolysis mixing pit observation panel, 20---the reagent playpipe, 21---the LED lamp; 22---the sheet electric heater, 23---pipeline, 24---the electric heater lead-in wire, 25---cylindric electric heater, 26---shell.
Embodiment
Below in conjunction with accompanying drawing the utility model is done further to detail.
One, the control procedure of the absorption of blood sample and dissolving, as shown in Figure 1:
A) when the instrument opening power, the just energising heating of the heating module that has metal soaking piece that the haemolysis mixing pit is outer, in design temperature ± 2 ℃, design temperature can be between 45～58 ℃ by its temperature stabilization of circuit control that Temperature Feedback is arranged.
B) priming line, solenoid valve 8 energisings are communicated with pipeline 10,9, and the piston of syringe 11 moves downward, the reagent that draw line 9 is connected.
C) flushing sampling probe 1, solenoid valve 7,8 no powers keep normality, and pipeline 10,12 connects, and pipeline 5,12 is communicated with, and the piston of syringe 11 moves upward, and reagent is released the flushing sampling probe.
D) flushing haemolysis mixing pit 3, solenoid valve 7 energisings, pipeline 12,6 connects; Solenoid valve 8 no powers keep normality, and pipeline 10,12 is communicated with; The piston of syringe 11 moves upward, and haemolysis reagent is released flushing haemolysis mixing pit 3, is discharged to waste liquid bottle by pipeline 14 then.
E) draw blood sample, solenoid valve 7,8 no powers keep normality; Pipeline 10,12 connects, and pipeline 5,12 is communicated with, after system to be driven drops to sampling probe in the blood sample; The piston of syringe 11 moves downward under the accurate control of stepper motor, draws the blood sample of 10-30 microlitre, sampling probe upwards mention leave the blood sample test tube after; Syringe continues to move downward, and the blood sample of drawing is left in the pipeline 12.
F) blood sample is injected the haemolysis mixing pit, solenoid valve 7 energisings, pipeline 6,12 are communicated with solenoid valve 8 no powers; Keep normality, pipeline 10,12 connects, and the piston of syringe 11 moves upward under the accurate control of stepper motor; With the blood sample that leaves in the pipeline 12; Be pushed in the haemolysis mixing pit 3, simultaneously, release an amount of haemolysis reagent and fully mix with blood.
G) blood sample heats about 100 seconds at haemolysis mixing pit mixed dissolution and by the heating arrangement outside the haemolysis mixing pit, remove unsettled composition after, be sent to corresponding analytic unit by auto-programming again and analyze.
Two, structure such as Fig. 2, shown in Figure 3 of the heating of haemolysis mixing pit, wherein:
3---haemolysis mixing pits, 4---have the metal soaking piece of electric heater; 16---pipeline nipple, 17---film sheet electric heater pressing plate; 18---heater holder, 19---haemolysis mixing pit observation panel, 20---haemolysis reagent playpipe; 21---LED lamp, 22, the sheet electric heater.
For the ease of observing the state of sample and haemolysis reagent, the haemolysis mixing pit preferably uses transparent materials such as glass, organic glass to process, and it is cylindrical that its profile can be made, and the bottom is conical, also can be other shapes.In order to make heat conduction good, haemolysis mixing pit 3 and have between the metal soaking piece 4 of electric heater and answer tight connecting.The 19th, haemolysis mixing pit observation panel for the ease of observing, has also installed LED lamp 21 additional.
Three, the description of pipeline heating
The sample that has added haemolysis reagent is in the heating of haemolysis mixing pit, and shortcoming is that heat time heating time is long, and the sample temperature rise is slow.Adopt pipeline heating haemolysis compositions and methods, can make blood sample moment by the good haemolysis reagent heating of preheating, better effects if.The pipeline synoptic diagram is seen accompanying drawing 4, and the pipeline heating component is serially connected in the middle of the pipeline 12, and pipeline 12 is divided into 12,13 two sections.
The sample of pipeline heating is drawn and the haemolysis process:
A) when the instrument opening power, the just energising heating of the heating module that has metal soaking piece of pipeline heater, in design temperature ± 2 ℃, design temperature can be between 45～58 ℃ by its temperature stabilization of circuit control that Temperature Feedback is arranged.
B) priming line, solenoid valve 8 energisings are communicated with pipeline 10,9, and the piston of syringe 11 moves downward, the haemolysis reagent that draw line 9 is connected.
C) flushing sampling probe 1, solenoid valve 7,8 no powers keep normality, and pipeline 10,12 connects, and pipeline 5,12 is communicated with, and the piston of syringe 11 moves upward, and haemolysis reagent is released the flushing sampling probe.
D) flushing haemolysis mixing pit 3, solenoid valve 7 energising pipelines 12,6 connect solenoid valve 8 no powers; Keep normality; Pipeline 5,12,13,10 is communicated with, and the piston of syringe 11 moves upward, and haemolysis reagent is released and process water back 23; Heated haemolysis reagent flushing haemolysis mixing pit 3 is discharged to waste liquid bottle through pipeline 14 then.
E) draw blood sample, solenoid valve 7,8 no powers keep normality; Pipeline 10,12 connects, and pipeline 5,12 is communicated with, after system to be driven drops to sampling probe in the blood sample; The piston of syringe 11 moves downward under the accurate control of stepper motor, draws the blood sample of 10-30 microlitre, sampling probe upwards mention leave the blood sample test tube after; Syringe continues to move downward, and the blood sample of drawing is left in the pipeline 12.
F) blood sample is injected the haemolysis mixing pit, solenoid valve 7 energisings, pipeline 6,12 are communicated with solenoid valve 8 no powers; Keep normality, pipeline 10,12 connects, and the piston of syringe 11 moves upward under the accurate control of stepper motor; With the blood sample that leaves in the pipeline 12, be pushed in the haemolysis mixing pit 3, simultaneously; In the ratio of regulation, release an amount of haemolysis reagent that was heated and fully mix with blood.
G) blood sample stops about 100 seconds at haemolysis mixing pit mixed dissolution, remove unsettled composition after, be sent to corresponding analytic unit by auto-programming again and analyze.
The twice of whole blood sample volume is answered >=drawn to volume in the pipeline 12; Add the accurate control of program; Should be able to make and carry out three, e) the blood pressure sample of the described absorption of bar leaves in the pipeline 12; But can not get into being heated in the pipeline 23 of pipeline heater, lost efficacy in order to avoid whole blood sample Yin Wendu is too high.
Volumes in the pipeline 13 should＞volume in the pipeline 23, want simultaneously＞the maximum diluted sample amount of drawing, like this, the haemolysis reagent of heating can not be drawn onto in the syringe.
Four, the structrual description of pipeline heating
Accompanying drawing 5,6 and accompanying drawing the 7, the 8th, plane pipeline heating arrangement synoptic diagram, stainless steel pipes is processed into the plane gradually opens spiral fashion, also can be processed into " U " font convoluted shape etc.; Use methods such as die cast metal; Make itself and soaking piece become the tight one that contacts, also can on the derby plane, be processed into corresponding pipeline groove, after pipeline is put into; Use the heat-conducting cream filling pore, make its heat conduction good.The plane electric heater is equipped with in one or both sides on the plane, supplies power to it by having the degenerative circuit of temperature, can make temperature constant design temperature ± 2 ℃ in.
Accompanying drawing the 9, the 10th, cylindric pipeline heating arrangement synoptic diagram; Stainless steel pipes is processed into cylindrical spiral fashion; Methods such as use die cast metal make itself and tubular metal soaking piece become the tight one that contacts, and also can on cylindrical metal, be processed into corresponding pipeline groove, after pipeline is put into; Use the heat-conducting cream filling pore, make its heat conduction good.In the center or the outside of tubular metal soaking piece, be equipped with cylindric or tubular electric heating.
Claims (5)
1. heating arrangements that is used for full-automatic saccharification hemoglobin analyser; Comprise the haemolysis mixing pit; It is characterized in that: the metal soaking piece that has electric heater is located at the inside of glycosylated hemoglobin analyser, and electrical heating mechanism is installed in outside the outer or pipeline of haemolysis mixing pit.
2. heating arrangements according to claim 1 is characterized in that: metal soaking piece and said haemolysis mixing pit tight connecting, haemolysis mixing pit are that cylindrical shape or upper end are the shape of cone for the right cylinder lower end.
3. heating arrangements according to claim 2 is characterized in that: said metal soaking piece is provided with haemolysis pond observation panel, is provided with the LED lamp.
4. heating arrangements according to claim 1 is characterized in that: metal soaking piece and said pipeline tight connecting, heated pipeline are the shapes that spirality or U word rotary type are gradually opened in cylindric spirality, plane.
5. heating arrangements according to claim 1 is characterized in that: on metal soaking piece, be provided with the pipe-line tank of inserting pipeline, and with the slit of heat-conducting glue fill pipe.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201120221213U CN202133580U (en) | 2011-06-28 | 2011-06-28 | Heating mechanism for fully automatic glycosylated hemoglobin analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201120221213U CN202133580U (en) | 2011-06-28 | 2011-06-28 | Heating mechanism for fully automatic glycosylated hemoglobin analyzer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202133580U true CN202133580U (en) | 2012-02-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201120221213U Expired - Lifetime CN202133580U (en) | 2011-06-28 | 2011-06-28 | Heating mechanism for fully automatic glycosylated hemoglobin analyzer |
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| Country | Link |
|---|---|
| CN (1) | CN202133580U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102645494A (en) * | 2012-04-25 | 2012-08-22 | 江苏奥迪康医学科技有限公司 | Internal heating device for clinical sample machine of glycosylated hemoglobin analyzer |
| CN106996885A (en) * | 2017-03-24 | 2017-08-01 | 江苏奥迪康医学科技股份有限公司 | Glycolated hemoglobin analysis melts blood pool and its pre-temperature method |
-
2011
- 2011-06-28 CN CN201120221213U patent/CN202133580U/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102645494A (en) * | 2012-04-25 | 2012-08-22 | 江苏奥迪康医学科技有限公司 | Internal heating device for clinical sample machine of glycosylated hemoglobin analyzer |
| CN102645494B (en) * | 2012-04-25 | 2013-06-26 | 江苏奥迪康医学科技有限公司 | Internal heating device for clinical sample machine of glycosylated hemoglobin analyzer |
| CN106996885A (en) * | 2017-03-24 | 2017-08-01 | 江苏奥迪康医学科技股份有限公司 | Glycolated hemoglobin analysis melts blood pool and its pre-temperature method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20120201 |