CN202041521U - Detection device for cell and experimental animal compatible phototoxicity experiment - Google Patents
Detection device for cell and experimental animal compatible phototoxicity experiment Download PDFInfo
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- CN202041521U CN202041521U CN2011201238822U CN201120123882U CN202041521U CN 202041521 U CN202041521 U CN 202041521U CN 2011201238822 U CN2011201238822 U CN 2011201238822U CN 201120123882 U CN201120123882 U CN 201120123882U CN 202041521 U CN202041521 U CN 202041521U
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Abstract
The utility model provides a detection device for a cell and experimental animal compatible phototoxicity experiment, which comprises a light-tight experiment module, and a plurality of ultraviolet lamps which are capable of emitting ultraviolet A (UVA) ultraviolet irradiation light sources of which the single wavelength is 365nm are arranged at the top part of the interior of the light-tight experiment module; a plurality of detachable cell culture solution cavities are arranged in the light-tight experiment module, and ultraviolet quartz windows respectively arranged on the cell culture solution cavities are used for protecting internal cell templates and isolating the internal cell templates from the outside and are used for receiving the irradiation of irradiation light; an incubation cavity is connected with an incubation controller and a cell culture solution feeder; an experimental animal is fixed by a plurality of detachable fixing mounts to receive the irradiation of the irradiation light; the interior of the experiment module is provided with an ultraviolet sterilizer, an ozone sterilizer, a ventilation controller and a humiture controller; the detection is carried out on the intensity of the irradiation light sources by irradiation light probes and is controlled by a computer; and experiment parameters can be stored in the computer or can be printed by a printer. The utility model has the beneficial effects that the detection device for the cell and experimental animal compatible phototoxicity experiment is provided and is applied to the fields of chemical engineering, toxicology, environmental protection, occupational disease prophylaxis, medical science and the like to carry out phototoxicity scientific research by using a cell or the experimental animal.
Description
Technical field:
The utility model relates to a kind of cell and animal used as test compatible optical toxicity test pick-up unit.
Background technology:
In the daily life, though many medicines and cosmetics of everyday use can not cause direct injury to human body, but under action of ultraviolet ray, for example operate under solar radiation, the ultraviolet environments etc. under the condition chemical reaction just can take place, thereby cause skin allergy or other forms of injury, be referred to as the phototoxicity injury that chemicals has on the specialty.This type of chemicals is carried out the phototoxicity test experience can prevent and alleviate the adverse effect that this class phototoxicity is brought to us.Existing phototoxicity identification experiment does not have the equipment of specialty, the employing animal does to test in the body and does not have the experiment of cell in vitro light poison mostly, and used light source is impure, and the inconsistent experimental result that causes of experimental situation is inaccurate, conventional efficient is low, and ultraviolet leakage can injure operating personnel.At above problem be badly in need of a kind of can accurately control experimental precision, safety, convenience, efficiently, the phototoxicity of cell and animal used as test compatibility tests checkout equipment to replenish blank in this respect.
Summary of the invention:
For addressing the above problem; the purpose of this utility model provides a kind of cell and animal used as test compatible optical toxicity test pick-up unit; can accurately control experimental precision, safety, convenience for relevant research experiment provides a kind of, test checkout equipment efficiently; for providing new method and apparatus, replenished blank in this respect at field research experiments in this regard such as chemical industry, toxicity health, environmental protection, work prophylaxis, medical science.
For achieving the above object, the technical solution of the utility model provides a kind of cell and animal used as test compatible optical toxicity test pick-up unit, this device comprises lighttight Laboratory Module body, and having several can send single wavelength at Laboratory Module body inner top is that the uviol lamp of UVA ultraviolet irradiation light source of 365nm is as experimental light sources; Several disconnectable cellular incubation sap cavities are arranged in it, the cell lamina membranacea can be fixed.The sliding rail that is provided with height in the Laboratory Module body and moves forward and backward, the convenient cellular incubation sap cavity and fixed mount height and front-back direction adjusted adapts to UVA ultraviolet irradiation light source irradiation.Cellular incubation sap cavity and fixed mount all can change, and can conveniently install or change cellular incubation sap cavity or fixed mount according to the experiment needs, carry out experiment of cell phototoxicity or animal phototoxicity experiment detection respectively, make device have compatibility.Being close to ultraviolet quartz window protection cell lamina membranacea above the cellular incubation sap cavity is isolated from the outside and accepts the ultraviolet irradiation light source irradiation; The incubation chamber connects required incubation controller and the cell culture fluid supply of cells survival; Fixed mount is used for fixing animal used as test and accepts radiation source irradiation and accept the irradiation that wavelength is the UVA ultraviolet source of 365nm; Ultraviolet and ozonateur, ventilation unit and temperature and humidity controller are arranged in the Laboratory Module, experimental situation is met the requirements; Be respectively equipped with the exposure light probe of two kinds of different wave lengths with cell lamina membranacea and fixed mount par position: the probe of UVA wavelength and UVB wavelength is that the main experiment light intensity of UVA ultraviolet irradiation light source of 365nm and the interference light intensity of UVB wavelength detect and by computing machine processes such as experiment light intensity and experiment condition controlled to single wavelength respectively, and parameters such as the process of experiment, result can be stored in the computing machine or by printer prints laboratory report list.
Effect of the present utility model is: provide a kind of and can accurately control experimental precision, safety, convenience, the phototoxicity experiment pick-up unit of cell and animal used as test compatibility efficiently; for providing new method and apparatus, replenished blank in this respect at field research experiments in this regard such as chemical industry, toxicity health, environmental protection, work prophylaxis, medical science.
Description of drawings:
Accompanying drawing 1 is the synoptic diagram of the utility model structure;
Among the figure:
1, ultraviolet disinfecting
2, UVA ultraviolet irradiation light source
3, ozonateur
4, ultraviolet quartz window
5, cell lamina membranacea
6, cellular incubation sap cavity
7, cell culture fluid supply
8, exposure light probe
9, incubation chamber
10, incubation controller
11, ultraviolet and ozonateur delay switch
12, exposure light proving installation
13, ventilation unit
14, temperature and humidity controller
15, time controller
16, computing machine
17, printer
18, Laboratory Module
19, fixed mount
20, sliding rail
Embodiment:
In conjunction with the accompanying drawings 1 and embodiment the utility model is illustrated.
As shown in Figure 1, the utility model device includes lighttight Laboratory Module 18, its top have several can send single wavelength be 365nm UVA ultraviolet irradiation light source 2 uviol lamp as the experiment radiation source; Several disconnectable cellular incubation sap cavities 6 are arranged in it, can cell lamina membranacea 5 is fixing, top ultraviolet quartz window 4 protection cell lamina membranaceas 5 are isolated from the outside and accept 2 irradiations of UVA ultraviolet irradiation light source; Incubation chamber 9 connects required incubation controller 10 and the cell culture fluid supply 7 of cells survival; The sliding rail 20 that is provided with height in Laboratory Module 18 bodies and moves forward and backward, the convenient cellular incubation sap cavity 6 and fixed mount 19 height and front-back direction adjusted adapts to 2 irradiations of UVA ultraviolet irradiation light source.Cellular incubation sap cavity 6 and fixed mount 19 all can change, and can conveniently install or change cellular incubation sap cavity 6 or fixed mount 19 according to the experiment needs, carry out experiment of cell phototoxicity or animal phototoxicity experiment detection respectively, make device have compatibility.There are the ultraviolet disinfecting 1 and the ozonateur 3 that 11 controls of ultraviolet and ozonateur delay switch are installed by inside all can open automatically and regularly close in the Laboratory Module 18, guarantee that experiment operates under aseptic condition by main frame or computing machine 16 controls; The ventilation unit 13 of light tight line and the temperature and humidity controller of control automatically 14 guarantee that the environment in Laboratory Module 18 bodies and the fixed mount 19 meets requirement of experiment.Time controller 15 control experimental periods; Be that the main experiment light intensity of UVA ultraviolet irradiation light source 2 of 365nm and the interference light intensity of UVB wavelength detect and controlled by processes such as computing machine 16 pairs of experiments light intensity and experiment conditions by exposure light proving installation 12 to single wavelength at the probe that is respectively equipped with the exposure light probe 8:UVA wavelength of two kinds of different wave lengths and UVB wavelength with cell lamina membranacea 5 par positions, parameters such as the process of experiment, result can be stored in the computing machine 16 or by printer 17 and print the laboratory report lists.
Embodiment:
Use the utility model device, can carry out the experiment of cell phototoxicity respectively detects or animal used as test phototoxicity test experience, when selecting the experiment of cell phototoxicity, at first open ultraviolet disinfecting 1 and ozonateur 3 each cellular incubation sap cavity 6 is carried out the sufficiently sterilised sterilization, open incubation controller 10 simultaneously, close ultraviolet and ozonateur delay switch 11 after the sterilization and also open the hermatic door and the ultraviolet quartz window 4 of Laboratory Module 18 immediately, the cell lamina membranacea of having handled in advance 5 is placed in the cellular incubation sap cavity 6,18 of closed ultraviolet quartz window 4 and Laboratory Modules, open cell culture fluid supply 7, open ventilation unit 13 and temperature and humidity controller 14 makes experimental situation reach requirement, adjusting sliding rail 20 height front and back positions makes cell lamina membranacea 5 fully shine, opening time controller 15 and irradiation flash ranging device 12 monitoring exposure time and intensity, the uviol lamp of opening wavelength and be the UVA ultraviolet irradiation light source 2 of 365nm begins cell phototoxicity test experience, experiment is omnidistance can be by the outside computing machine 16 at-once monitor adjustment that connect, and experiment parameter can be stored in the computing machine 16 that is connected or by printer 17 print processing.Computing machine 16 can cut out the UVA ultraviolet irradiation light source 2 that wavelength is 365nm automatically after experiment was finished; The cell lamina membranacea 5 that takes out illuminated mistake by relevant regulation and standard carry out this kind chemical substance to the evaluation of dermoreaction intensity to draw this experimental result.
When experimentizing the experiment of animal phototoxicity, open ultraviolet disinfecting 1 and ozonateur 3 each fixed mount 19 is carried out the sufficiently sterilised sterilization, close ultraviolet and ozonateur delay switch 11 after the sterilization and also open the hermatic door of Laboratory Module 18 immediately, the fixed mount 19 that installs animal used as test is placed in the Laboratory Module, the height front and back position of adjusting sliding rail 20 makes animal used as test be shone fully, the hermatic door of closed Laboratory Module 18, open ventilation unit 13 and temperature and humidity controller 14 makes experimental situation reach requirement, opening time controller 15 and irradiation flash ranging device 12 monitoring exposure time and intensity, the UVA ultraviolet irradiation light source 2 of opening wavelength and be 365nm begins animal used as test is made the phototoxicity test experience, experiment is omnidistance can be by the outside computing machine 16 at-once monitor adjustment that connect, and experiment parameter can be stored in the computing machine 16 that is connected or by printer 17 print processing.Computing machine 16 can cut out the UVA ultraviolet irradiation light source 2 that wavelength is 365nm automatically after experiment was finished; The experimenter take out fixed mount 19 by relevant regulation and standard carry out this kind chemical substance to the evaluation of dermoreaction intensity to draw this experimental result.
Claims (5)
1. cell and animal used as test compatible optical toxicity test pick-up unit, it is characterized in that: this device comprises lighttight Laboratory Module (18) body, and having several can send single wavelength at Laboratory Module (18) body inner top is that the UVA ultraviolet irradiation light source (2) of 365nm is as experimental light sources; Several disconnectable cellular incubation sap cavities (6) are arranged in Laboratory Module (18) body, can fixed cell lamina membranacea (5), on cellular incubation sap cavity (6), there is ultraviolet quartz window (4) protection cell shuttering (5) to be isolated from the outside and accepts UVA ultraviolet irradiation light source (2) irradiation that wavelength is 365nm; The sliding rail (20) that is provided with height and moves forward and backward in Laboratory Module (18) body is conveniently adjusted the position and is changed cellular incubation sap cavity (6) and fixed mount (19); Is that the experiment light intensity of the UVA ultraviolet irradiation light source (2) of 365nm detects and controlled testing processes such as light intensity and experiment condition by computing machine (16) being respectively equipped with exposure light probe (8) with cell lamina membranacea (5) and fixed mount (19) par position to single wavelength; Inner ultraviolet disinfecting (1), the ozonateur (3) of Laboratory Module body (18) guarantees to test to be operated under aseptic condition; Ventilation unit (13) and temperature and humidity controller (14) guarantee that the environment in Laboratory Module (18) body meets requirement of experiment; Parameters such as the process of experiment, result can be stored in the computing machine (16) or by printer (17) and print the laboratory report list.
2. a kind of cell according to claim 1 and animal used as test compatible optical toxicity test pick-up unit, it is characterized in that: this device is provided with height and moves forward and backward in Laboratory Module (18) body sliding rail (20), the convenient cellular incubation sap cavity (6) and fixed mount (19) height and front-back direction adjusted adapts to UVA ultraviolet irradiation light source (2) irradiation; Cellular incubation sap cavity (6) and fixed mount (19) all can change, can conveniently install or change cellular incubation sap cavity (6) or fixed mount (19) according to the experiment needs, carry out experiment of cell phototoxicity or animal phototoxicity experiment detection respectively, make device have compatibility.
3. a kind of cell according to claim 1 and animal used as test compatible optical toxicity test pick-up unit, it is characterized in that: several disconnectable cellular incubation sap cavities (6) are arranged in Laboratory Module (18) body, a plurality of cell lamina membranaceas (5) can be fixed in the cellular incubation sap cavity (6), connecting cell culture fluid supply (7) in the cellular incubation sap cavity (6) provides nutrition at any time the cell lamina membranacea (5) in the cellular incubation sap cavity (6), cellular incubation sap cavity (6) and cell lamina membranacea (5) are in same incubation chamber (9), and incubation chamber (9) connect incubation controller (10) and guarantee cellular incubation sap cavity (6) and cell lamina membranacea (5) and the inner essential temperature of experimental cell existence.
4. a kind of cell according to claim 1 and animal used as test compatible optical toxicity test pick-up unit is characterized in that: lighttight Laboratory Module (18) body inner close fitting cell lamina membranacea (5) in cellular incubation sap cavity (6) and its to be had ultraviolet quartz window (4) can protect cell shuttering (5) to be isolated from the outside above just and accepts the irradiation that wavelength is the UVA ultraviolet irradiation light source (2) of 365nm; Be that the main experiment light intensity of UVA ultraviolet irradiation light source (2) of 365nm and the stray light intensity of UVB wavelength detect and by computing machine (16) processes such as experiment light intensity and experimental situation controlled to single wavelength at the exposure light probe (8) that is equipped with monitoring UVA and two kinds of wavelength of UVB with cell lamina membranacea (5) and fixed mount (19) par position, parameters such as the process of experiment, result can be stored in the computing machine (16) or by printer (17) printing laboratory report list.
5. a kind of cell according to claim 1 and animal used as test compatible optical toxicity test pick-up unit, it is characterized in that: ultraviolet disinfecting (1) is installed in Laboratory Module body (18) inside and ozonateur (3) all can be opened automatically and regularly be closed by main frame or computer control, and the assurance experiment is operated under aseptic condition; The temperature and humidity controller (14) of ventilation unit of light tight line (13) and control automatically guarantees that the environment in Laboratory Module (18) body meets requirement of experiment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011201238822U CN202041521U (en) | 2011-04-25 | 2011-04-25 | Detection device for cell and experimental animal compatible phototoxicity experiment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011201238822U CN202041521U (en) | 2011-04-25 | 2011-04-25 | Detection device for cell and experimental animal compatible phototoxicity experiment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202041521U true CN202041521U (en) | 2011-11-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011201238822U Expired - Lifetime CN202041521U (en) | 2011-04-25 | 2011-04-25 | Detection device for cell and experimental animal compatible phototoxicity experiment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202041521U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102253169A (en) * | 2011-04-25 | 2011-11-23 | 天津开发区合普工贸有限公司 | Cell and experimental animal compatible-type phototoxicity experimental test equipment |
-
2011
- 2011-04-25 CN CN2011201238822U patent/CN202041521U/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102253169A (en) * | 2011-04-25 | 2011-11-23 | 天津开发区合普工贸有限公司 | Cell and experimental animal compatible-type phototoxicity experimental test equipment |
| CN102253169B (en) * | 2011-04-25 | 2014-05-07 | 天津开发区合普工贸有限公司 | Cell and experimental animal compatible-type phototoxicity experimental test equipment |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee | ||
| CP02 | Change in the address of a patent holder |
Address after: 300110 Tianjin city Nankai District Weishui road win atlas building 2-602 Patentee after: Tianjin Development Zone Hepu Industry and Trade Co., Ltd. Address before: 300020 Xinjiang Road, Heping District, Tianjin, No. 9 Patentee before: Tianjin Development Zone Hepu Industry and Trade Co., Ltd. |
|
| AV01 | Patent right actively abandoned |
Granted publication date: 20111116 Effective date of abandoning: 20140507 |
|
| RGAV | Abandon patent right to avoid regrant |