CN202036455U - Experimental device for rat respiratory tract obstruction model - Google Patents
Experimental device for rat respiratory tract obstruction model Download PDFInfo
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- CN202036455U CN202036455U CN2011200243414U CN201120024341U CN202036455U CN 202036455 U CN202036455 U CN 202036455U CN 2011200243414 U CN2011200243414 U CN 2011200243414U CN 201120024341 U CN201120024341 U CN 201120024341U CN 202036455 U CN202036455 U CN 202036455U
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Abstract
The utility model discloses an experimental device for a rat respiratory tract obstruction model, which is characterized by comprising a cylinder. The cylinder is arranged horizontally, one end of the cylinder is closed, the other end of the cylinder is connected with a cylinder cover, and a fan and a protective net is arranged in the cylinder cover; and the outer side of the cylinder close to the end connected with the cylinder cover is provided with an air inlet communicated with the inside of the cylinder, and the outer side of the cylinder close to the closed end of the cylinder is provided with a gas outlet communicated with the inside of the cylinder. The non-invasive induced cultivation of an animal model with syndromes of obstructive sleep apnea hypopnea can be achieved. The animal model cultivated with the device has good stability and repeatability, and the device is relatively simple and has high operability. Moreover, animals can be easily obtained and have a small size and are economical.
Description
Technical field
This utility model relates to a kind of experimental provision of Non-Invasive rats breathing blocking model.
Background technology
The respiratory obstruction model is a kind of animal model of being set up for research respiratory obstruction syndrome.The obstructive sleep apnea low syndrome is meant, go up during sleep air flue subside block the asphyxia that causes and hypoventilation, with snoring, Sleep architecture disorder, frequently diseases such as blood oxygen saturation descends, daytime is drowsiness take place. people's life is learnt to cause very big influence, even the danger of sudden death is arranged.Therefore, setting up an animal model that meets experiment purpose has great significance to the further further investigation of this type of disease.
At present the foundation of respiratory obstruction model is to produce mandatory asphyxia by operation method, and these class methods are wound property, and are bigger to animal injury, also influence the observational study to pharyngeal structure organization simultaneously, and experiment effect is had a greatly reduced quality.
Summary of the invention
The purpose of this utility model provides a kind of device that can noninvasively turn out the rats breathing blocking model.
For reaching above purpose, this utility model adopts following technical scheme to be achieved:
A kind of experimental provision that is used for the rats breathing blocking model is characterized in that, comprises the cylindrical shell of horizontally disposed end sealing, and the other end of cylindrical shell is connected with dismountable cover, is provided with fan and protection network in the cover; Described cylindrical shell near be communicated with in the arranged outside of cover link has air inlet and cylindrical shell, described cylindrical shell near the arranged outside of cylindrical shell blind end the gas outlet is arranged and cylindrical shell is interior is communicated with.
In the such scheme, described cover is threaded with being connected to of cylindrical shell.Described protection network and cover 1 are connected as a single entity.Described air inlet has two, is symmetrical arranged along barrel diameter.
This utility model is at meiofaunas such as rats, in the process of using this device cultivation respiratory obstruction model, by the oxygen concentration in air inlet and the gas outlet automaton, induce rat that the respiratory obstruction phenomenon takes place, thereby the syndromic natural history of simulation obstructive sleep apnea low is realized the foundation of no wound animal breath blocking model.
Adopt this device cultured animals model can simulate the obstruction sleep apnea syndrome preferably, model stability, good reproducibility, facility are simple relatively, and be workable, and animal is easy to obtain, and build is less, cost economy.
Description of drawings
Below in conjunction with the drawings and the specific embodiments this utility model is described in further detail.
Fig. 1 is an outside drawing of the present utility model.
Fig. 2 is that the A-A of Fig. 1 is to cutaway view.
Among Fig. 1 Fig. 2: 1, cylindrical shell; 2, first air inlet; 3, cover; 4, second air inlet; 5, gas outlet; 6, fan; 7, protection network.
The specific embodiment
Shown in Figure 2 as Fig. 1, a kind of experimental provision that is used for the rats breathing blocking model comprises the cylindrical shell 1 that a horizontally disposed end seals, and the other end of cylindrical shell 1 is connected with cover 3, is provided with fan 6 and protection network 7 in the cover 3; Cylindrical shell feeds 100% N respectively near having two along symmetric air inlet 2,4 of barrel diameter and 1 interior connection of cylindrical shell with the arranged outside of cover link
2And air; Cylindrical shell has one or two gas outlet 5 and 1 interior connection of cylindrical shell near the arranged outside of cylindrical shell blind end, and outside unidirectional conducting valve is all inserted in gas outlet 5. so just can keep the constant pressure in the cylindrical shell 1.
More specifically, cylindrical shell 1 is the cylindrical resin glass container, diameter 10cm, long 28cm, and cover 3 is detachable, and for keeping sealing, cover 3 is threaded with being connected to of cylindrical shell 1.Fan 6 in the cover 3 can keep the air in the container fully to circulate.The protection network 7 (plastic material) that fan 6 is provided with previously can prevent that rat and fan from bumping, and this protection network and cover 1 are connected as a single entity.The volume of cover 1 is not counted in the device volume.
Claims (4)
1. an experimental provision that is used for the rats breathing blocking model is characterized in that, comprises the cylindrical shell of horizontally disposed end sealing, and the other end of cylindrical shell is connected with dismountable cover, is provided with fan and protection network in the cover; Described cylindrical shell near be communicated with in the arranged outside of cover link has air inlet and cylindrical shell, described cylindrical shell near the arranged outside of cylindrical shell blind end the gas outlet is arranged and cylindrical shell is interior is communicated with.
2. the experimental provision that is used for the rats breathing blocking model as claimed in claim 1 is characterized in that, described cover is threaded with being connected to of cylindrical shell.
3. the experimental provision that is used for the rats breathing blocking model as claimed in claim 1 is characterized in that described protection network and cover are connected as a single entity.
4. the experimental provision that is used for the rats breathing blocking model as claimed in claim 1 is characterized in that described air inlet has two, is symmetrical arranged along barrel diameter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011200243414U CN202036455U (en) | 2011-01-25 | 2011-01-25 | Experimental device for rat respiratory tract obstruction model |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011200243414U CN202036455U (en) | 2011-01-25 | 2011-01-25 | Experimental device for rat respiratory tract obstruction model |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202036455U true CN202036455U (en) | 2011-11-16 |
Family
ID=44963930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011200243414U Expired - Fee Related CN202036455U (en) | 2011-01-25 | 2011-01-25 | Experimental device for rat respiratory tract obstruction model |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202036455U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103021249A (en) * | 2012-12-31 | 2013-04-03 | 东莞市人民医院 | Heating carbon dioxide simulating abdominal cavity experimental box |
| CN105167902A (en) * | 2015-10-28 | 2015-12-23 | 刘茹涵 | Cabin for treating breathing disorder |
| CN105853016A (en) * | 2016-04-28 | 2016-08-17 | 首都医科大学附属北京安贞医院 | Modeling device for mouse with OSAHS (obstructive sleep apnea hypopnea syndrome) |
-
2011
- 2011-01-25 CN CN2011200243414U patent/CN202036455U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103021249A (en) * | 2012-12-31 | 2013-04-03 | 东莞市人民医院 | Heating carbon dioxide simulating abdominal cavity experimental box |
| CN103021249B (en) * | 2012-12-31 | 2015-02-04 | 东莞市人民医院 | Heating carbon dioxide simulating abdominal cavity experimental box |
| CN105167902A (en) * | 2015-10-28 | 2015-12-23 | 刘茹涵 | Cabin for treating breathing disorder |
| CN105853016A (en) * | 2016-04-28 | 2016-08-17 | 首都医科大学附属北京安贞医院 | Modeling device for mouse with OSAHS (obstructive sleep apnea hypopnea syndrome) |
| CN105853016B (en) * | 2016-04-28 | 2017-06-27 | 首都医科大学附属北京安贞医院 | Obstruction sleep apnea-hypopnea syndrome mouse model modeling device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20111116 Termination date: 20140125 |