The utility model content
A purpose of the present utility model provides a kind of reservoir bag system, and it can be convenient to obtain the sample in the storage in batches, avoids the damage of whole sample.
Another purpose of the present utility model provides a kind of reservoir bag system, its make sample from sampling, handle to the process that stores and all be in confined space, reduce the chance of polluting.
For reaching above purpose, this utility model provides a kind of reservoir bag system, and it comprises: a pre-treatment portion, and it is provided with at least one internal element, at least one inlet and at least one outlet; And at least one reservoir, it is provided with at least one internal element and at least one inlet; The inlet of wherein aforementioned pre-treatment portion imports and stores thing, and the inlet of aforementioned reservoir links by the mode that liquid phase is communicated with the outlet of aforementioned pre-treatment portion.
Preferably, aforementioned reservoir further is provided with at least one outlet, and it links by the mode that liquid phase is communicated with at least one internal element of aforementioned reservoir.
Preferably, the mode that is communicated with of the liquid phase between the outlet of the inlet of aforementioned reservoir and aforementioned pre-treatment portion is to be communicated with by a connecting pipe.
Preferably, aforementioned communicating pipe is a dismountable type communicating pipe.
Preferably, the outlet of the inlet of aforementioned communicating pipe and aforementioned reservoir and aforementioned pre-treatment portion is one-body molded.
Preferably, the internal element of aforementioned pre-treatment portion links by the mode that liquid phase is communicated with the outlet of at least one aforementioned pre-treatment portion.
Preferably, aforementioned pre-treatment portion is provided with two internal elements, and wherein the internal element of each aforementioned pre-treatment portion links by the mode that liquid phase is communicated with the outlet of an aforementioned pre-treatment portion at least.
Preferably, at least one internal element of aforementioned reservoir links by the mode that liquid phase is communicated with aforementioned pre-treatment portion respectively.
Preferably, the common and aforementioned pre-treatment of at least one internal element of aforementioned reservoir portion links by the mode that liquid phase is communicated with.
Preferably, aforementioned pre-treatment portion comprises two inlets, and one of them inlet imports and stores thing, and another inlet imports freezing preservative agent.
Preferably, aforementioned reservoir is provided with two internal elements.
Preferably, the volume ratio of two of aforementioned reservoir internal elements is 1~10.
Preferably, the volume ratio of two of aforementioned reservoir internal elements is 5~10.
Preferably, the aforementioned storage bags system comprises a plurality of aforementioned reservoir.
This utility model provides a kind of reservoir bag system in addition, and it comprises:
One pre-treatment portion, it is provided with at least one internal element, at least one inlet and at least one outlet; And at least one reservoir, it is provided with at least one internal element and at least one inlet; Wherein, the outlet of the inlet of aforementioned reservoir and aforementioned pre-treatment portion links; Wherein, the aforementioned storage bags system further comprises a sealing strip, each aforementioned internal element and aforementioned pre-treatment portion by the sealing bar each other liquid be not connected.
Preferably, aforementioned storage bags system stores periphery blood, Cord blood or cell suspending liquid.
Preferably, the aforementioned storage bags system further comprises a sealing strip, and it further separates out the internal element that liquid is not connected between the internal element with the internal element of aforementioned pre-treatment portion and aforementioned reservoir in the internal element of aforementioned pre-treatment portion.
In sum, reservoir bag of the present utility model system is by the integraty design of pre-treatment portion and reservoir, and the sample that makes storage is finished storage and all handled in confined space from collecting, and reduces the risk of polluting.In addition, the separation design by reservoir can reach and obtain the purpose that the part sample is tested or used in batches, and avoid the damage of whole sample.
The specific embodiment
This utility model is about a kind of reservoir bag system of novelty, and it can simply be divided into pre-treatment portion and two parts of reservoir; Wherein aforementioned pre-treatment portion is provided with at least one internal element, at least one inlet and at least one outlet; Aforementioned reservoir is provided with at least one internal element and at least one inlet; The inlet of wherein aforementioned pre-treatment portion stores thing in order to import, and the outlet binding of the inlet of aforementioned reservoir and aforementioned pre-treatment portion.
" binding " described in the utility model is meant plural member with the direct or indirect combination of physics mode, the state that it comprises the liquid energy or can not circulate between aforementioned plural member.
" liquid phase connection " described in the utility model or " connection " are meant that liquid is able to circulate between aforementioned plural member.Feasible ground, the inlet of aforementioned reservoir links in the mode that liquid phase is communicated with the outlet of aforementioned pre-treatment portion.It is noted that, in this manual, unless specialize, so-called " binding " or " connection " all has the implication that liquid is circulated.
The mode of finishing aforementioned " liquid phase connection " is unrestricted, and for instance, the mode that the liquid phase between the outlet of the inlet of aforementioned reservoir and aforementioned pre-treatment portion is communicated with can be as simple as the extension of aforementioned inlet and outlet, or finishes by a connecting pipe.Can be a dismountable type communicating pipe aforementioned communicating pipe, and can make aforementioned reservoir and aforementioned pre-treatment portion's binding or separation according to circumstances.
In an embodiment of the present utility model, further comprise a sealing strip, its can:
Be not in the state that liquid phase is communicated with between the internal element that makes aforementioned reservoir and the internal element of another aforementioned reservoir;
Be not in the state that liquid phase is communicated with between the internal element that makes arbitrary aforementioned reservoir and the aforementioned pre-treatment portion; And/or
In the internal element of aforementioned pre-treatment portion, further separate out the internal element that liquid is not connected between the internal element with aforementioned internal element and aforementioned reservoir.
Aforementioned pre-treatment portion is used to receive the sample that desire stores, temporarily to deposit sample and/or to carry out the necessary processing measure.With the blood sample is example, and the blood sample of newly obtaining must elder generation and cryoprotective agent, the glycerol as 5~10% or DMSO mixing before carrying out stored frozen.Preferably, aforementioned pre-treatment portion is provided with two inlets at least, goes into confession for one and imports sample; another inlet is then for importing required reagent (cryoprotective agent as described above); in view of the above, just can make the blood sample of obtaining in confined space, finish processing, reduce the risk of polluting.Aforementioned pre-treatment portion can comprise at least one internal element, and wherein each internal element is provided with at least one aforementioned outlet, for obtaining the material that is stored in wherein or linking with the inlet of aforementioned reservoir.The set-up mode of aforementioned internal element is separated with a next door to set up, or sets up with a sealing strip further separation in the former internal element that pre-exists.
Aforementioned reservoir is the ultimate unit of stored substance in the reservoir bag of the present utility model system.In an embodiment of the present utility model, aforementioned reservoir is divided at least one internal element through a next door, to reach the purpose of store/taking in batches in batches.Aforementioned next door is available for users to simply with instrument (as, shears) aforementioned internal element to be separated through design.
In an embodiment of the present utility model, the internal element of aforementioned reservoir may be at the same time or separately links in the mode that liquid phase is communicated with aforementioned pre-treatment portion with an inlet.The aforementioned internal element of at least one of aforementioned reservoir is provided with an outlet, for obtaining the material that is stored in wherein.
In an embodiment of the present utility model, aforementioned reservoir is provided with two internal elements; Feasible ground, the volume ratio of aforementioned two internal elements is 1~10; Preferably, the volume ratio of aforementioned two internal elements is 5~10.
The form of aforementioned outlet can perhaps, for instance, may be an elastic construction as the structure of the blood outlet of traditional blood bag, and it can insert for the syringe needle of syringe and be unlikely to destroy the structure of whole reservoir bag system.Aforementioned inlet and/or aforementioned the outlet in operation can temporarily be sealed or open by any existing means.
Reservoir bag of the present utility model system is used to store any biological material; For instance, as, peripheral blood, Cord blood or cell suspending liquid.
The material of all members need not special restriction in the reservoir bag of the present utility model system, the existing plastic type material matter that is suitable for low temperature (according to appointment-196~-197 ℃) long term storage all can be used in the affiliated in principle field, include, but are not limited to: polyethylene, vinyl-vinyl acetate copolymer, fluororesin, poly-imines silicone, abs polymer (acrylonitrile/butadiene/styrene polymer), Merlon or its combination.
Following examples will be arranged in pairs or groups accompanying drawing so that details of the present utility model to be described, it is noted that, following examples only are used for example formula ground explanation characteristic of the present utility model and advantage, and be not used in the scope of restriction this utility model claim.In addition, the following drawings is only illustrated various feasible mode of the present utility model, and desire does not limit form of the present utility model.What need be careful especially is that the ratio of all members and relative position all only have exemplary effect in the accompanying drawing, and not necessarily are equal to actual situation.
Embodiment one: reservoir bag of the present utility model system one
Please join Fig. 1, the reservoir bag system 100 of present embodiment comprises a pre-treatment portion 110 and three reservoir 120.
Aforementioned pre-treatment portion 110 is provided with an internal element 111, and the inlet 112,113 that is communicated with it.Aforementioned internal element 111 also links an outlet 114 to link with an aforementioned reservoir 120.
Aforementioned reservoir 120 is divided into a bigger internal element 122 and a less internal element 123 through a next door 121.Aforementioned internal element 122 and 123 common is communicated with an inlet 124, and aforementioned internal element 122 and export 125 and be communicated with.The capacity of aforementioned internal element 122 is 10 milliliters, and the capacity of aforementioned internal element 123 is 1 milliliter.
With one of them reservoir 120 is example, and aforementioned pre-treatment portion 110 links by the inlet 124 of aforementioned outlet 114 with aforementioned reservoir 120, makes to store thing and be able to be passed to aforementioned reservoir 120 from aforementioned pre-treatment portion 110.
Aforementioned storage bags system 100 is used to store Cord blood.In use, can be in advance 113 cryoprotective agent (DMSO) be inserted aforementioned internal element 111 from entering the mouth, the Cord blood that desire is stored 112 imports from entering the mouth again, makes Cord blood and cryoprotective agent uniform mixing in aforementioned internal element 111.When operating on the practice, can simply aforementioned storage bags system 100 be positioned on the desktop, and make the level height of aforementioned reservoir 120 be higher than the level height of aforementioned pre-treatment portion 110.In view of the above, can make appropriate in aforementioned pre-treatment portion 110, the mixing of Cord blood and reagent, and temporarily not flow in the aforementioned reservoir 120.
Then, after Cord blood and reagent mix, make aforementioned pre-treatment portion 110 and aforementioned reservoir 120 place the par height (preferably again, make the level height of aforementioned pre-treatment portion 110 be higher than the level height of aforementioned reservoir 120), just can make Cord blood flow into inlet 124, and enter internal element 122,123 respectively through aforementioned outlet 114.
At last, treat that aforementioned internal element 122,123 is equipped with the Cord blood that the institute desire stores after, along potted line 130 the bag heat-sealing of reservoir bag system 100 is formed a sealing strip with heat sealing machine.By the sealing bar, will be in the state that liquid must not be connected between the aforementioned internal element 122,123 of aforementioned reservoir 120, do not have liquid communication again between the internal element 111 of same aforementioned internal element 122,123 and aforementioned pre-treatment portion 110 yet.In view of the above, can be again along potted line 130 with destructive means, as shears, aforementioned pre-treatment portion 110 is separated with aforementioned reservoir 120, and aforementioned reservoir 120 is placed a card casket, to be stored in liquid nitrogen.
In the future, if will use Cord blood in the storage, can aforementioned internal element 123 be separated with aforementioned internal element 122 simply with destructive means, and separately internal element 123 is taken out to carry out necessary check.Thus, and can avoid in the part blood of taking, making other Cord blood in storing to thaw and damage.
Embodiment two: reservoir bag of the present utility model system two
Please join Fig. 2, the reservoir bag system 200 of present embodiment comprises a pre-treatment portion 210 and five reservoir 220.
Aforementioned pre-treatment portion 210 is provided with an internal element 211 and two inlets 212,213.Aforementioned internal element 211 also links outlet 214,215 to link with an aforementioned reservoir 220.Aforementioned pre-treatment portion 210 is provided with an outlet 216 in addition.
Aforementioned reservoir 220 is divided into a bigger internal element 222 and a less internal element 223 through a next door 221, and is provided with that inlet 224 and 225 is respectively independent to be communicated with aforementioned internal element 222 and 223.Aforementioned internal element 222 also 226 is communicated with an outlet.The capacity of aforementioned internal element 222 is 5 milliliters, and the capacity of aforementioned internal element 223 is 1 milliliter.
Aforementioned storage bags system 200 is used to store Cord blood.In use, can be in advance 213 cryoprotective agent (DMSO) be inserted aforementioned internal element 211, again the Cord blood that collects 212 is imported from entering the mouth, make Cord blood and cryoprotective agent uniform mixing in aforementioned internal element 211 from entering the mouth.When operating on the practice, can simply aforementioned storage bags system 200 be positioned on the desktop, and make the level height of aforementioned reservoir 220 be higher than the level height of aforementioned pre-treatment portion 2 10.In view of the above, can make appropriate in aforementioned pre-treatment portion 210, the mixing of Cord blood and reagent, and temporarily not flow in the aforementioned reservoir 220.
Then, after Cord blood and reagent mix, make aforementioned pre-treatment portion 210 and aforementioned reservoir 220 place the par height (preferably again, make the level height of aforementioned pre-treatment portion 2 10 be higher than the level height of aforementioned reservoir 220), just can make Cord blood flow into internal element 222,223 respectively through aforementioned outlet 214,215.
Then, can the heat-sealing of the bag of reservoir bag system 200 be formed a sealing strip along potted line 230, by the sealing bar, to be in the state that liquid must not be connected between the aforementioned internal element 222,223 of aforementioned reservoir 220, also not have liquid communication again between the internal element 211 of same aforementioned internal element 222,223 and aforementioned pre-treatment portion 210.
At this moment,, can simply adjust the angle of reservoir bag system 200, make the Cord blood of retention be gathered in a side that is provided with outlet 216 in the internal element 211 if still there is Cord blood to retain in the internal element 211 of aforementioned pre-treatment portion 210.Then, again along bag heat-sealing formation one sealing strip of potted line 231 with reservoir bag system 200.By the sealing bar, can in original internal element 211, form an internal element 217 independently, and this internal element 217 just can become an easy reservoir.
At last, can be again along potted line 230,231 with destructive means, aforementioned pre-treatment portion 210 is separated with aforementioned reservoir 220, and aforementioned internal element 211 separated with aforementioned internal element 217, and respectively aforementioned reservoir 220 and aforementioned internal element 217 are placed the card casket, to be stored in liquid nitrogen.
In the future, if will use Cord blood in the storage, can aforementioned internal element 223 be separated with aforementioned internal element 222 simply with destructive means, and separately internal element 223 is taken out to carry out necessary check.Thus, and can avoid in the part blood of taking, making other Cord blood in storing to thaw and damage.
Embodiment three: reservoir bag of the present utility model system three
Please join Fig. 3, the reservoir bag system 300 of present embodiment comprises a pre-treatment portion 310 and five reservoir 320.
Aforementioned pre-treatment portion 310 is provided with an internal element 311, and the inlet 312,313 that is communicated with aforementioned internal element and export 314.
Aforementioned reservoir 320 is separated out a bigger internal element 322 and a less internal element 323 through a next door 321.Aforementioned internal element 322 and 323 common is communicated with an inlet 324, and aforementioned internal element 322 and export 325 and be communicated with.The capacity of aforementioned internal element 322 is 10 milliliters, and the capacity of aforementioned internal element 323 is 1 milliliter.
The inlet 324 of each aforementioned reservoir 320 extends linking a connecting pipe 340, and aforementioned communicating pipes 340 end outer wall be provided with screw thread 341, screw to extend the joint portion 315 that is provided with the outlet 314 of aforementioned pre-treatment portion 310.In view of the above, aforementioned internal element 311 and communicating pipe 340 and reservoir 320 are linked, to reach the state of liquid communication.
The reservoir bag system 300 of present embodiment is used to store the blood cell cell suspending liquid.When using, communicating pipe 340 and joint portion 315 are screwed, so that pre-treatment portion 310 links with reservoir 320.Then, behind the required reagent (as: freezing preservative agent) of 313 importings that enter the mouth, the blood cell cell suspending liquid that stores from the 312 importing desires that enter the mouth makes it mix in internal element 311 with aforementioned agents more in advance.When operating on the practice, can simply aforementioned storage bags system 300 be positioned on the desktop, and make the level height of aforementioned reservoir 320 be higher than the level height of aforementioned pre-treatment portion 310.In view of the above, can make appropriate in aforementioned pre-treatment portion 310, the mixing of cell suspending liquid and reagent, and temporarily not flow in the aforementioned reservoir 320.
Then, after cell suspending liquid and reagent mix, make aforementioned pre-treatment portion 310 and aforementioned reservoir 320 place the par height (preferably, make the level height of aforementioned pre-treatment portion 310 be higher than the level height of aforementioned reservoir 320), just can make cell suspending liquid flow into the internal element 322,323 of aforementioned reservoir 320.Thereafter, along bag heat-sealing formation one sealing strip of potted line 330 with reservoir bag system 300.By the sealing bar, make aforementioned internal element 322,323 be in the state that liquid phase is communicated with independently of one another and no longer.At last, after reservoir 320 being separated with communicating pipe 340 with destructive means along potted line 330, just reservoir 320 can be placed the card casket, to be stored in liquid nitrogen.
In the future, if will use cell suspending liquid in the storage, can aforementioned internal element 323 be separated with aforementioned internal element 322 simply with destructive means, and separately internal element 323 is taken out to carry out necessary experiment.Thus, and can avoid in the part sample of taking, making other cell suspending liquid in storing to thaw and damage.
In addition, if the internal element 322,323 in all aforementioned reservoir 320 all fills up, and when still leaving cell suspending liquid in the internal element 311, can make the screwing communicating pipe 340 of reservoir 320 of joint portion 315 and another one sky, remaining cell suspending liquid be imported in the empty internal element 322,323 store again.
Characteristics of the present utility model are that by structure configuration of the present utility model, the internal element of aforementioned reservoir is used to store the sample from same source, and the internal element of aforementioned reservoir is stored in identical comparatively speaking condition of storage; More particularly, the horizontal level of the internal element of aforementioned reservoir in the liquid nitrogen bucket can be consistent, and guarantees that the interior sample of each internal element of aforementioned reservoir is stored in the storage condition that can be considered identical, as identical storage temperature.In view of the above, the sample that is stored in one of them internal element of aforementioned reservoir can be used for carrying out coherent detection, and this testing result, for example: cytoactive, source etc., can analogize the state of the sample of other internal element.
The those skilled in the art be when can understanding, under this utility model spirit, and the various variations that can carry out according to this case embodiment.Therefore, obvious listed embodiment is not in order to restriction this utility model, but attempt is covered by the modification of being made in spirit of the present utility model and the category under the definition of claims scope.