CN201699881U - Video capturing device of animal centrifugal machine - Google Patents

Video capturing device of animal centrifugal machine Download PDF

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Publication number
CN201699881U
CN201699881U CN2010202253914U CN201020225391U CN201699881U CN 201699881 U CN201699881 U CN 201699881U CN 2010202253914 U CN2010202253914 U CN 2010202253914U CN 201020225391 U CN201020225391 U CN 201020225391U CN 201699881 U CN201699881 U CN 201699881U
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China
Prior art keywords
animal
centrifuge
rotating shaft
centrifugal machine
machine rotating
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Expired - Fee Related
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CN2010202253914U
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Chinese (zh)
Inventor
熊利泽
马玉林
孙静
董海龙
桑韩飞
栾琪
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Fourth Military Medical University FMMU
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Fourth Military Medical University FMMU
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Priority to CN2010202253914U priority Critical patent/CN201699881U/en
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Abstract

The utility model belongs to medical experiment equipment, in particular to a video capturing system of an animal centrifugal machine. The video capturing device is characterized by leastways comprising a centrifugal machine rotating shaft and a centrifugal machine rotating shaft driving mechanism, wherein the centrifugal machine rotating shaft is vertically connected with a centrifugal machine rotating arm, so that the centrifugal machine rotating arm is parallel with a centrifugal machine base; the other end of the horizontal centrifugal machine rotating arm is provided with a fixed animal experiment platform; a camera of a wireless camera unit is fixed at the position where the horizontal centrifugal machine rotating arm is close to the centrifugal machine rotating shaft; the camera is focused on the animal experiment platform; the wireless camera unit is used for extracting the animal image information of the fixed animal experiment platform; and a controlling and computing unit is used for receiving, storing and analyzing the animal image information and judging whether the animal losses the consciousness when a centrifugal machine rotating shaft driving mechanism drives the centrifugal machine rotating shaft to rotate and the centrifugal machine rotating shaft drives the fixed animal experiment platform at the other end of the centrifugal machine rotating arm to centrifugally rotate around the shaft. The video capturing device provides the foundation for researching, preventing and curing the pathological and physiological mechanism of the cerebral injury caused by the positive acceleration.

Description

The animal centrifuge video harvester
Technical field
The utility model belongs to medical experiment equipment, animal centrifuge video harvester particularly, it is by observing the performance of rat in animal centrifuge, thereby set up the rat model of brain damage due to the positive acceleration that centrifuge produces, comprising the design and the collecting image of computer analysis of the special fixture of rat.
Background technology
Fighter plane does motor-driven or during aerobatics, the centripetal acceleration direction that is produced is pointed to canopy by the passenger cabin bottom.Under this accelerated motion situation, the pilot must be subjected to the centrifugal inertial force effect opposite with acceleration, and its direction is by head points pelvis (foot).Claim that in aeromedicine this acceleration is a positive acceleration, the inertia force that the pilot is subjected to is expressed as+Gz.In recent years, high-performance fighter aircraft can produce high G value (〉 9G in maneuvering flight), rapid onset rate (〉 6G/s) continuation+Gz, and occur repeatedly.The physiological effect of+Gz mainly shows as the health apparent weight to be increased, and organ deforms, is shifted along the inertia force direction, and hydrostatic pressure difference increases, and blood generation inertia shifts and redistribution, thereby causes various physiological function obstacles.The pilot threatened maximum be exactly+the loss of consciousness (G-LOC) that Gz causes.Think that at present G-LOC mainly is because under+Gz effect, the horizontal arterial pressure of brain reduces, the cerebral blood flow (CBF) minimizing, and then cause (Kurihara et al, 2007 due to brain tissue ischemic, the anoxic; McKinley et al, 2005; Ossard et al, 1994).Confirm in the animal experiment study of this respect+cerebral ischemia that Gz causes can cause brain damage and damage in learning and memory (Cao XS, et al, 2007; Sun XQ, et al, 2005), be the important topic of domestic and international Research Aviation Medicine so prevent and treat the cerebral ischemia that positive acceleration causes.
In the basic research of this respect, the conventional animal centrifuge produces positive acceleration and sets up the cerebral ischemic model that the loss of consciousness takes place animal, because the special operational condition (high speed rotating) of animal centrifuge, limited some advanced physiology monitoring The Application of Technology, at present when setting up the animal model of simulation G-LOC, the index that the loss of consciousness takes place the monitoring animal mainly contains: the horizontal arterial blood platen press of monitoring eye, 50% death rate method, the heart rate halving method, electrocardio disappearance method, (Sun Xiqing etc. such as brain wave disappearance method, 2009), we think and judge that by these indexs the defective that the loss of consciousness exists takes place animal at first is not directly perceived, and have predictive.
Rat is fixed in when rotating on the animal centrifuge pivoted arm, requires the rat cephalocaudal axis parallel, and head is towards the centrifuge axle center with the pivoted arm major axis.In the zoopery in the past; on the centrifuge fixedly the device of animal (rat) be a rectangle box; can not regulate size; rat retraction, rotary head can occur even self-protection gonosome position such as turn round in box; thereby weakened+influence of Gz; the success that is difficult to like this guarantee model becomes we carry out prophylactico-therapeutic measures research on this model basis bottleneck with stable.
Summary of the invention
But the purpose of this utility model provides a kind of intuitive analysis animal behavior state performance, find out rule, and then the animal centrifuge video harvester of G-LOC takes place in the judgement animal, thereby set up the G-LOC animal model, the pathophysiological mechanism and the prophylactico-therapeutic measures that cause brain damage for research positive acceleration provide stable basis.
The purpose of this utility model is achieved in that the animal centrifuge video harvester, it is characterized in that: comprise a centrifuge rotating shaft at least, centrifuge rotating shaft driving mechanism, the centrifuge rotating shaft is connected with the centrifuge pivoted arm is vertical, make the centrifuge pivoted arm parallel with the centrifuge base station, the horizontal centrifuge pivoted arm other end is the zoopery platform fixedly, the shooting of one wireless camera unit is fixed on the position of horizontal centrifuge pivoted arm 7 near the centrifuge rotating shaft, quickcam image focusing is on the zoopery platform, the wireless camera unit is with extracting the fixedly animal painting information of zoopery platform, be sent to a control computation unit by wireless mode, when the rotating shaft of centrifuge rotating shaft drive mechanism centrifuge is rotated, the centrifuge rotating shaft drives the fixing zoopery platform of the centrifuge pivoted arm other end when the centrifugal rotation of axle, control computation unit receives storage to animal painting information and analyzes, and judge whether animal the loss of consciousness (G-LOC) has taken place, when the loss of consciousness (G-LOC) does not take place, continue to quicken centrifugal rotation zoopery platform, drive the animal centrifugal motion; When the loss of consciousness (G-LOC) took place, control computation unit provided information, and control centrifuge rotating shaft driving mechanism stops operating.
It is raising rotating speed at interval that drive animal centrifugal motion is changeed in described control centrifuge rotating shaft drive mechanism centrifuge rotating shaft.
Described control computation unit animal painting information is received storage and analyze comprise extract that struggle state, the passivity head of animal under apocarpy in the image raise position and time of origin, fore paw grab the state of climbing, mouth breathing, spasm and time of origin, respiration rate, time and image when eyeball color different conditions produces.
Described fixedly zoopery platform comprises a U type support, animal passenger cabin, height adjusting ring, chest retainer plate, head movement framing mask, the animal passenger cabin is fixed in the U type support, U type support and horizontal centrifuge pivoted arm are fixed together, the animal passenger cabin is round tubular structure, round tubular structure one end is a hatch door, height adjusting ring, chest retainer plate are arranged in the chamber, and another outlet of round tubular structure has the head movement framing mask.
Advantage of the present utility model is: at first, the fixture of rat is in strict accordance with the status requirement design of animal in centrifuge, prevents that rat from taking the protectiveness position, so that farthest observe the behavior state performance of rat when G-LOC takes place; The second, can gather the preservation video again by observing the behavior state of animal in centrifuge judge the generation of animal G-LOC intuitively in real time, so that further playback analysis afterwards; The 3rd, animal model success rate height, the good stability of the simulation G-LOC that sets up by this method, the pathophysiological mechanism and the prophylactico-therapeutic measures that cause brain damage for research positive acceleration provide stable basis.
Description of drawings
Fig. 1 is rat fixture (passenger cabin) structural representation;
Fig. 2 is video acquisition system structural representation (having added passenger cabin);
Fig. 3 is the system hardware connection diagram.
Among the figure: 1. hatch door; 2. height adjusting ring; 3. chest retainer plate; 4. head movement framing mask; 5. wireless camera unit; 6. lighting source; 7. centrifuge pivoted arm; 8. signal receiver; 9. signal amplifier; 10. centrifuge rotating shaft outer cover; 11. signal cable; 12. centrifuge rotating shaft; 13. control computation unit; 14, centrifuge rotating shaft driving mechanism; 15, zoopery platform; 16, centrifuge base station.
Embodiment
As Fig. 1, Fig. 2 and shown in Figure 3, the animal centrifuge video harvester, at least comprise a centrifuge rotating shaft 12, centrifuge rotating shaft driving mechanism 14, centrifuge rotating shaft 12 and 7 vertical connections of centrifuge pivoted arm, make centrifuge pivoted arm 7 parallel with centrifuge base station 16, horizontal centrifuge pivoted arm 7 other ends are zoopery platform 15 fixedly, the shooting of one wireless camera unit is fixed on the position of horizontal centrifuge pivoted arm 7 near centrifuge rotating shaft 12, quickcam image focusing is on zoopery platform 15, wireless camera unit 5 usefulness are extracted the fixedly animal painting information of zoopery platform 15, be sent to a control computation unit 13 by wireless mode, when driving centrifuge rotating shaft 12, centrifuge rotating shaft driving mechanism 14 rotates, centrifuge rotating shaft 12 drives the fixing zoopery platform 15 of centrifuge pivoted arm 7 other ends when the centrifugal rotation of axle, 13 pairs of animal painting information of control computation unit receive storage and analyze, and judge whether animal the loss of consciousness (G-LOC) has taken place, when the loss of consciousness (G-LOC) does not take place, continue to quicken centrifugal rotation zoopery platform 15, drive the animal centrifugal motion; When the loss of consciousness (G-LOC) took place, control computation unit 13 provided information, and control centrifuge rotating shaft driving mechanism 14 stops operating.
Control centrifuge rotating shaft driving mechanism 14 drives centrifuge rotating shaft 12 commentaries on classics and drives the raising rotating speed that the animal centrifugal motion is the interval.
13 pairs of animal painting information of described control computation unit receive storage and analyze comprise extract that struggle state, the passivity head of animal under apocarpy in the image raise position and time of origin, fore paw grab the state of climbing, mouth breathing, spasm and time of origin, respiration rate, time and image when eyeball color different conditions produces.
Described fixedly zoopery platform 15 comprises a U type support, animal passenger cabin, height adjusting ring 2, chest retainer plate 3, head movement framing mask 4, the animal passenger cabin is fixed in the U type support, U type support and horizontal centrifuge pivoted arm 7 are fixed together, the animal passenger cabin is round tubular structure, round tubular structure one end is a hatch door 1, height adjusting ring 2, chest retainer plate 3 are arranged in the chamber, and another outlet of round tubular structure has head movement framing mask 4.
At first rat is fixed in the passenger cabin (3-5 minute clear-headed fully) after sucking anesthetic (enflurane or Isoflurane or Sevoflurane) anesthesia fast, as shown in Figure 1, select suitable chest retainer plate 3 to be fixed on thorax top according to the diameter of rat thorax, guarantee not influence its breathe make again its in cylinder can not before scurry and can not retreat; Regulate and fix the position of height adjusting ring 2 again according to the height of rat, influence the breathing of animal like this with regard to the animal health is elongated; Regulate the size of head movement framing mask 4; Close hatch door 1 at last.
Passenger cabin is fixed on the video acquisition device that has wireless camera unit 5 and lighting source 6, as shown in Figure 2, wireless camera unit 5 and lighting source 6 all have gimballed base, adjust the position of camera and the position of focal length and light source, the target of shooting focusing and illumination is at head and the fore paw of rat.
Video acquisition device is fixed on the animal centrifuge pivoted arm 7, and the major axis of video acquisition device is parallel to the major axis of pivoted arm in the time of fixedly, and head is towards centrifuge rotating shaft 12 axle center.
Control computation unit 13 connects wireless signal receiver 8, signal amplifier 9, signal receiver 8 is fixed on the centrifuge pivoted arm 7 top centrifuge rotating shaft outer covers 10, signal cable 11 strides across the pivoted arm top and enters observation room connection computer, open system, debug signal, move centrifuge behind the signal stabilization, monitor the behavior state performance of rat in real time.
The utility model it should be noted that:
1) rat is fixed in the device of particular design (passenger cabin), select the fixedly thorax top of rat of suitable chest retainer plate according to the diameter of rat thorax earlier, make its in cylinder can not before scurry and can not retreat, regulate and fix the position of height adjusting ring again according to the height of rat, influence the breathing of animal like this with regard to the animal health is elongated, regulate the size of head movement framing mask at last; 2) passenger cabin is fixed on the video acquisition device that has wireless camera unit and lighting source, adjusts the position of camera and the position of focal length and light source; 3) video acquisition device is fixed in the animal centrifuge pivoted arm; 4) connect wireless signal receiver and computer, gather and preserve video in real time; 5) animal centrifuge parameter (acceleration magnitude, jolt, the duration of runs) is set, the operation centrifuge.
The behavior state performance in the centrifuge that runs up of real-time monitored and playback analyzing rat, observation index comprises: struggle state, passivity head are raised the change of grabbing the state of climbing, mouth breathing, spasm and time of origin, respiration rate, eyeball color of position and time of origin, fore paw, the change of eyeball color can be carried out quantitative measurement to redness wherein by image analysis software, can reflect the blood supply of animal brain so indirectly.Observation and analysis by these indexs, find out the monitoring index of judging the animal generation loss of consciousness (G-LOC), thereby determine to set up the operational factor (acceleration magnitude, jolt, the duration of runs) of centrifuge when simulating the loss of consciousness (G-LOC) animal model.
Signal between camera and the receiver is a wireless transmission, transmission range is limited, there is very strong electromagnetic interference around the animal centrifuge again, for guaranteeing the stable of vision signal, guaranteeing personal security and do not influencing under the prerequisite of centrifuge operation, the distance between camera and the receiver be to shorten as far as possible, wherein in the signal transmission, signal amplifier and anti-interference parts are added with.

Claims (3)

1. animal centrifuge video harvester, it is characterized in that: comprise a centrifuge rotating shaft (12), centrifuge rotating shaft driving mechanism (14), centrifuge rotating shaft (12) and vertical connection of centrifuge pivoted arm (7), make centrifuge pivoted arm (7) parallel with centrifuge base station (16), horizontal centrifuge pivoted arm (7) other end is zoopery platform (15) fixedly, the shooting of one wireless camera unit (5) is fixed on the position of horizontal centrifuge pivoted arm (7) near centrifuge rotating shaft (12), quickcam image focusing is on zoopery platform (15), wireless camera unit (5) is sent to a control computation unit (13) with extracting the fixedly animal painting information of zoopery platform (15) by wireless mode.
2. animal centrifuge video harvester according to claim 1 is characterized in that: described control centrifuge rotating shaft driving mechanism (14) drives centrifuge rotating shaft (12) commentaries on classics and drives the raising rotating speed that the animal centrifugal motion is the interval.
3. animal centrifuge video harvester according to claim 1, it is characterized in that: described fixedly zoopery platform (15) comprises a U type support, the animal passenger cabin, height adjusting ring (2), chest retainer plate (3), head movement framing mask (4), the animal passenger cabin is fixed in the U type support, U type support and horizontal centrifuge pivoted arm (7) are fixed together, the animal passenger cabin is round tubular structure, round tubular structure one end is hatch door (1), height adjusting ring (2) is arranged in the chamber, chest retainer plate (3), another outlet of round tubular structure has head movement framing mask (4).
CN2010202253914U 2010-06-13 2010-06-13 Video capturing device of animal centrifugal machine Expired - Fee Related CN201699881U (en)

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CN2010202253914U CN201699881U (en) 2010-06-13 2010-06-13 Video capturing device of animal centrifugal machine

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Application Number Priority Date Filing Date Title
CN2010202253914U CN201699881U (en) 2010-06-13 2010-06-13 Video capturing device of animal centrifugal machine

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU192472U1 (en) * 2018-12-28 2019-09-17 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Device for creating gravitational overload

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU192472U1 (en) * 2018-12-28 2019-09-17 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Device for creating gravitational overload

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Granted publication date: 20110105

Termination date: 20150613

EXPY Termination of patent right or utility model