CN201655741U - Device improving detection efficiency of 3D ion trap - Google Patents
Device improving detection efficiency of 3D ion trap Download PDFInfo
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- CN201655741U CN201655741U CN2009202955685U CN200920295568U CN201655741U CN 201655741 U CN201655741 U CN 201655741U CN 2009202955685 U CN2009202955685 U CN 2009202955685U CN 200920295568 U CN200920295568 U CN 200920295568U CN 201655741 U CN201655741 U CN 201655741U
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- ion trap
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Abstract
The utility model relates to a device improving detection efficiency of a 3D ion trap, which is characterized in that the device comprises a first detector, an electronic lens and a second detector, the first detector is arranged on the first side of the 3D ion trap and used for detecting ions emitted from the first side of the 3D ion trap, the electronic lens is arranged on the second side of the 3D ion trap and is convenient for the ions to pass through so that the ions can enter the 3D ion trap, and the second detector is arranged on the side of the electronic lens and used for detecting ions which are emitted from the second side of the 3D ion trap and deflected through the electronic lens. The device has the advantages of high ion detection efficiency, high ionization efficiency, simple structure and the like.
Description
Technical field
The utility model relates to the 3D ion trap, particularly a kind of device that improves the 3D ion trap detection efficiency.
Background technology
Mass spectrometry is to realize a kind of method to the sample qualitative and quantitative analysis by the analysis to the sample ions mass-to-charge ratio.Mass spectrometric basic composition all comprises ion source, mass analyzer, detector and vacuum system.Ionogenic effect is with sample ionization to be analyzed, obtains having the ion of sample message.
As shown in Figure 1, a kind of internal electrical that generally adopts from the 3D ion trap, comprise the electron source 209, electron lens 208,3D ion trap, the detector 204 that set gradually, companies such as Varian, Thermo all use said structure.
Above-mentioned ion trap is in analytic process, and ion can be from the direction outgoing of two endcap electrodes, and can only detect an outgoing ion on the direction.As seen, the detection efficiency of ion is the highest in theory can only to arrive 50%, and this made the matter worse with regard to not strong 3D ion trap originally beyond doubt to the ion storage ability.
At present, most of producers all fail to address the above problem.Have only the solution that has proposed " triple resonant " in the product of Varian, be specially:
Catch dipole field TFD (Trapping Field Dipole) by on endcap electrode, applying one, make the field misalignment geometric center of ion trap; Applying on endcap electrode simultaneously provides the ion parametric oscillation to assist the alternation quadrupole field, and the alternation dipole field that the vibration of ion side frequency is provided, nonlinear resonance in conjunction with hexapole field, make ion be more prone to from the distance a closer endcap electrode on outgoing, thereby improved ion detection efficient.But triple resonant still exists with some shortcomings, as:
1, during triple resonant excites, part ion outgoing is in the opposite direction arranged still.
2, when the energy of resonant excitation signal strengthened, the ion populations of outgoing in the opposite direction can increase, thereby reduced ion detection efficient.And when the energy of excitation signal was big more, the detection efficiency of ion was low more.
3, for making the physical centre that catches the field depart from geometric center, need on termination electrode, apply RF and produce TFD, simultaneously also need to apply RF on the ring electrode, promptly use two-way RF mode (and RF need be coupled with AC), increased the complexity of circuit and the complexity of control greatly by coil.And because the close detector of endcap electrode, the loading of RF brings radio frequency interference easily, influences signal quality.
4, need to add extra auxiliary dipole field and level Four field in the triple resonant, because the introducing of these multipole fields has increased nonlinear effect, the poor controllability of system, the skew that also may bring mass number.
The utility model content
In order to solve above-mentioned deficiency of the prior art, the utility model provides a kind of device of the 3D of raising ion trap detection efficiency, and the detection efficiency of existing 3D ion trap is doubled, and the theoretical value of detection efficiency can reach 100%; Also improved simultaneously the Ionization Efficiency of sample.
For achieving the above object, the utility model adopts following technical scheme:
A kind of device that improves the 3D ion trap detection efficiency specifically comprises:
Be arranged on first side of 3D ion trap, be used to detect first detector of 3D ion trap from the ion of this side outgoing;
Be arranged on the electron lens of 3D ion trap second side, be convenient to electronics across and into described 3D ion trap;
Be arranged on second detector of described electron lens sidepiece, be used to detect from second side outgoing of 3D ion trap and the ion after electron lens deflection.
As preferably, described electron lens comprises first electrode and second electrode that is oppositely arranged, and second electrode is provided with the hole that cooperates with described second detector.
Further, described first electrode is provided with the hole, also is provided with the dynode that cooperates with this hole.
Further, described hole is provided with mesh electrode.
As preferably, described first electrode and second electrode are halfpipes.
Compared with prior art, the utlity model has following beneficial effect:
1, ion detection efficient height.
Be provided with cathode lens, make the outgoing ion of 3D ion trap all be detected, theoretic ion detection efficient can reach 100%.
Be not subjected to the influence of resonant excitation signal, no matter under which kind of situation, detection efficiency all is the twice of existing 3D ion trap.
2, sample ions efficient height.
The cathode lens that is provided with is used for focused electron on the one hand, improves the Ionization Efficiency of sample, is used for the ion of deflection from the outgoing of 3D ion trap on the other hand, so that be detected; Be used to control whether passing through of electronics on the one hand again, play the effect of electronic gate.
Description of drawings
Fig. 1 is the structural representation of 3D ion trap in the prior art;
Fig. 2 is the structural representation of device among the embodiment 1;
Fig. 3 is the structural representation of cathode lens in the utility model;
Fig. 4 is the structural representation of device among the embodiment 2;
Fig. 5 is the structural representation of device among the embodiment 3;
Fig. 6 is the structural representation of device among the embodiment 4.
Embodiment
Below in conjunction with drawings and Examples, the utility model is described in further details.
Embodiment 1:
As shown in Figure 2, a kind of device that improves the 3D ion trap detection efficiency is applied in the mass spectrometer, and described mass spectrometer comprises electron source 209, second electron lens 208, cathode lens, 3D ion trap and first detector 204 that sets gradually.
Described 3D ion trap comprises hyperboloid ring electrode 201, hyperboloid endcap electrode 202,203.First detector 204 is arranged on a side of endcap electrode 202.
As shown in Figure 3, described cathode lens comprises that semi-tubular first electrode 206 and second electrode, 207, the first electrodes 206 and second electrode 207 are oppositely arranged, and the electricity isolation, so that load different voltage.Described second electrode 207 is provided with hole 211, and the position relative with this hole 211 is provided with second detector 205.Hole 211 usefulness mesh electrodes cover, and the electric field error so that the compensation perforate causes focuses on the electronics that passes through better, and mesh electrode allows ion to pass through simultaneously.
Described cathode lens plays the effect of focused electron in the ionization stage, plays the effect of deflect ions in mass analysis stage, is detected by second detector 205 so that the ion after the deflection passes described hole 211.
Present embodiment has also disclosed a kind of method of the 3D of raising ion trap detection efficiency, is applied in the mass spectral analysis, and characteristics are:
In the ionization stage:
High pressure on first detector 204 and second detector 205 is closed, and detector is in off position;
Apply positive voltage or suitable negative voltage on second electron lens 208, (second electron lens 208 conducts) electronic gate is opened at this moment; The electronics that electron source 209 produces can pass through second electron lens 208.
Apply identical voltage on first electrode 206 and second electrode 207, this moment, first electrode 206 and second electrode 207 were combined, and were equivalent to electron focusing lens;
In mass analysis stage:
Apply high pressure on first detector 204 and second detector 205, detector enters detected state;
Apply negative voltage (this voltage should be lower than the direct current biasing on the electron source 209) on the second electron lens 208, (second electron lens 208 conducts) electronic gate is closed at this moment, and electronics can not pass through second electron lens 208;
On first electrode 206, apply positive voltage, then apply negative voltage or ground connection on second electrode 207,3D ion trap outgoing ion from the both direction: a part of ion is from endcap electrode 203 outgoing, effect of electric field deflect in first electrode 206 and 207 formation of second electrode, pass the aperture 211 on second electrode 207, thereby detected by second detector 205; Another part ion is detected by first detector 204 from endcap electrode 202 outgoing.
Therefore the ion of outgoing can both be detected from the 3D ion trap both direction, has improved the detection efficiency of ion significantly, and detection efficiency can reach 100% in theory.Cathode lens has further focused on electronics, has improved the Ionization Efficiency of sample.
Embodiment 2:
As shown in Figure 3, Figure 4, a kind of device that improves the 3D ion trap detection efficiency, as different from Example 1: between the cathode lens and second detector, ion focusing set of lenses 301 is set, is used to reduce dispersing of ion, further improve the detection efficiency of ion.
Present embodiment has also disclosed a kind of method of the 3D of raising ion trap detection efficiency, and as different from Example 1: ion enters ion focusing set of lenses 301 after penetrating from cathode lens, is detected by second detector afterwards.The ion focusing set of lenses can design different lens numbers as required, and the voltage on it can reach best ion focusing effect according to actual conditions optimization.
Embodiment 3:
As shown in Figure 5, a kind of device that improves the 3D ion trap detection efficiency, as different from Example 1:
1, above first detector, is provided with the first high energy dynode 401.
2, be provided with hole 212 on first electrode 206, the position relative with this hole 212 is provided with the second high energy dynode 402.Hole 212 usefulness mesh electrodes cover, and the electric field error so that the compensation perforate causes focuses on the electronics that passes through better, and mesh electrode allows ion to pass through simultaneously.
Present embodiment has also disclosed a kind of method of the 3D of raising ion trap detection efficiency, as different from Example 1:
In mass analysis stage:
Apply negative voltage on first electrode 206, and apply positive voltage on second electrode 207.
The 3D ion trap is from both direction outgoing ion, enters the first high energy dynode 401 from the ion of endcap electrode 202 outgoing, detected by first detector from the electronics of these dynode 401 outgoing; Under the electric field action of ion through first electrode 206 and 207 formation of second electrode of endcap electrode 203 outgoing, to enter the second high energy dynode 402 through via hole 212, after the electronics of these dynode 402 outgoing passes cathode lens, be detected by second detector.
Owing to be provided with two high energy dynodes, further improved ion detection efficient.
Embodiment 4:
As Fig. 3, shown in Figure 6, a kind of device that improves the 3D ion trap detection efficiency, as different from Example 1:
1, second electron lens 208 no longer is set.
2, the length of first electrode 206, second electrode 207 is greater than the 211 close endcap electrodes 203 of the hole on embodiment 1, the second electrode 207.
Present embodiment has also disclosed a kind of method of the 3D of raising ion trap detection efficiency, is applied in the mass spectral analysis, and characteristics are:
In the ionization stage:
High pressure on first detector 204 and second detector 205 is closed, and detector is in off position;
Apply identical positive voltage or suitable negative voltage on first electrode 206 and second electrode 207, cathode lens is opened as electronic gate;
In mass analysis stage:
Apply high pressure on first detector 204 and second detector 205, detector enters detected state;
Apply positive voltage on first electrode 206, then apply negative voltage or ground connection on second electrode 207, at this moment, cathode lens is closed as electronic gate, has stopped passing of (electron source 209 produces) electronics; Simultaneously, 3D ion trap outgoing ion from the both direction: a part of ion is from endcap electrode 203 outgoing, in the electric field action deflect of first electrode 206 and 207 formation of second electrode, pass the aperture 211 on second electrode 207, thereby detected by second detector 205; Another part ion is detected by first detector 204 from endcap electrode 202 outgoing.
Therefore the ion of outgoing can both be detected from the 3D ion trap both direction, has improved the detection efficiency of ion significantly, and detection efficiency can reach 100% in theory.Cathode lens has focused on the electronics of electron source outgoing, has improved the Ionization Efficiency of sample.
Above-mentioned execution mode should not be construed as the restriction to the utility model protection range.Key of the present utility model is: first side in the 3D ion trap is provided with first detector, second side is provided with cathode lens, cathode lens is used to control that electronics passes, ion deflecting, second detector is arranged on the sidepiece of cathode lens, is used to detect the ion after cathode lens deflection from the second side outgoing of 3D ion trap.Under the situation that does not break away from the utility model spirit, any type of change that the utility model is made all should fall within the protection range of the present utility model.
Claims (5)
1. device that improves the 3D ion trap detection efficiency, it is characterized in that: described device comprises:
Be arranged on first side of 3D ion trap, be used to detect first detector of 3D ion trap from the ion of this side outgoing;
Be arranged on the electron lens of 3D ion trap second side, be convenient to electronics across and into described 3D ion trap;
Be arranged on second detector of described electron lens sidepiece, be used to detect from second side outgoing of 3D ion trap and the ion after electron lens deflection.
2. the device of raising 3D ion trap detection efficiency according to claim 1, it is characterized in that: described electron lens comprises first electrode and second electrode that is oppositely arranged, and second electrode is provided with the hole that cooperates with described second detector.
3. the device of raising 3D ion trap detection efficiency according to claim 2, it is characterized in that: described first electrode is provided with the hole, also is provided with the dynode that cooperates with this hole.
4. according to the device of claim 2 or 3 described raising 3D ion trap detection efficiencies, it is characterized in that: described hole is provided with mesh electrode.
5. according to the device of claim 2 or 3 described raising 3D ion trap detection efficiencies, it is characterized in that: described first electrode and second electrode are halfpipes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009202955685U CN201655741U (en) | 2009-12-29 | 2009-12-29 | Device improving detection efficiency of 3D ion trap |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009202955685U CN201655741U (en) | 2009-12-29 | 2009-12-29 | Device improving detection efficiency of 3D ion trap |
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| CN201655741U true CN201655741U (en) | 2010-11-24 |
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| CN2009202955685U Expired - Fee Related CN201655741U (en) | 2009-12-29 | 2009-12-29 | Device improving detection efficiency of 3D ion trap |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112799120A (en) * | 2019-11-13 | 2021-05-14 | 中国科学院国家空间科学中心 | Double-channel electrostatic analyzer for ion and electron synchronous measurement |
-
2009
- 2009-12-29 CN CN2009202955685U patent/CN201655741U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112799120A (en) * | 2019-11-13 | 2021-05-14 | 中国科学院国家空间科学中心 | Double-channel electrostatic analyzer for ion and electron synchronous measurement |
| CN112799120B (en) * | 2019-11-13 | 2024-03-22 | 中国科学院国家空间科学中心 | Dual-channel electrostatic analyzer for synchronous measurement of ions and electrons |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20101124 Termination date: 20131229 |