CN201591058U - Mouse sleep depriving device for medical experiment - Google Patents

Mouse sleep depriving device for medical experiment Download PDF

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Publication number
CN201591058U
CN201591058U CN2010200205691U CN201020020569U CN201591058U CN 201591058 U CN201591058 U CN 201591058U CN 2010200205691 U CN2010200205691 U CN 2010200205691U CN 201020020569 U CN201020020569 U CN 201020020569U CN 201591058 U CN201591058 U CN 201591058U
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China
Prior art keywords
casing
mouse
water
island
tried
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Expired - Fee Related
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CN2010200205691U
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Chinese (zh)
Inventor
铁茹
于军
张学策
周幸春
杨芳
陈健康
曲萍
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Fourth Military Medical University FMMU
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Fourth Military Medical University FMMU
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Priority to CN2010200205691U priority Critical patent/CN201591058U/en
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Abstract

The utility model discloses a mouse sleep depriving device for medical experiment. The device comprises a tank body loaded with water. A plurality of island platforms above the water level are arranged in the tank body, and the dimension only allows the test mouse to stand. The device is characterized in that rod bodies upwards extend on the four corners of the tank body; a light source is arranged at the end of the rod body; the middle of the upper edge of the tank body in the length or width direction is symmetrically provided with a rotary camera which is connected with a computer through signals, and the rotary camera is used for shooting up the test mouse on any island platform in the tank body in any direction; the tank body is provided with a net cover, and a net-like V-shaped eating tank for the test mouse to take foods is arranged under the net cover.

Description

The muroid sleep deprivation device that is used for medical experiment
Technical field
The utility model relates to a kind of animal sleep of medical experiment and deprives device.Be particularly related to a kind of sleep deprivation device that is used for the muroid medical experiment.
Background technology
In recent years, sleep deprivation or sleep forfeiture be army under the state of emergency particularly wartime common phenomena very, being to cause the combatant tired depleted, forfeiture fighting capacity to take place, one of key factor of cutting personnel occurs, also is that army is at tissue with continue an important military medicine problem doing must consider wartime.The sleep deprivation problem may be more outstanding under the high-tech war condition in future, and foreign military has given very big attention to this, and it is brought up to forage in wartime, ammunition supply height of equal importance treat, and in the research of actively strengthening this respect.Therefore the medical experiment that animal sleep is deprived is subject to people's attention day by day, existing a kind of simple muroid sleep deprivation device normally is provided with the island platform that several are higher than the water surface in a casing that fills water, island platform size can only allow rat stand, when being tried to fall in the water when mouse falls asleep, deprive the sleep that is tried mouse thus, thereby realize zoologizeing the purpose of behavior behind the sleep deprivation.But the problem that this muroid sleep deprivation device exists is: the one, and during the experimental period overlength (24 hours), the observer also produces fatigue, can not guarantee the continuity of testing; The 2nd, water is too cold or under the winter situation, is tried mouse and falls into interference behaviors such as easily producing stress reaction in the water, and influence is to being tried the accuracy of mouse sleep deprivation behavioral study.
Summary of the invention
The purpose of this utility model provides a kind of sleep deprivation device of novel omnibearing shooting observed and recorded muroid medical experiment, has scientific structure, operates easy characteristics.
For reaching above purpose, the utility model takes following technical scheme to be achieved:
A kind of muroid sleep deprivation device that is used for medical experiment comprises that one fills the casing of water, is provided with the island platform that several are higher than the water surface in the casing, island platform size only allows to be tried mouse and stands, it is characterized in that be extended with the body of rod on described casing four angles, body of rod end is provided with light source; The center, upper edge of casing length direction or width is arranged with the rotating camera that is connected with Computer signal, can comprehensively photograph the mouse of being tried on the platform of the interior arbitrary island of casing; Described casing is provided with guard, and the guard below is provided with to being tried the netted V-arrangement crib of mouse for food.
In the such scheme, described casing one side bottom is provided with delivery port UNICOM outlet pipe under water; The casing opposite side top of this water outlet oral-lateral is provided with water inlet UNICOM water inlet pipe, and outlet pipe, water inlet pipe are connected to the outer thermostatical water bath of a casing.Described island platform is along the setting in one line of casing length direction, and each island platform can be changed according to being tried the mouse bodily form.Described netted V-arrangement crib is arranged on guard below between two island platforms along the casing width.
Employing has light source and the utility model device of the rotating camera of the comprehensive shooting that links to each other with calculator,, can well guarantee the continuity of testing to make more science of experimental result as 24 hours in the overlength experimental period; Can the long preservation experimental result, and can preserve, delete, print it; Can access experimental record and new experimental result contrast in the past at any time.Be better than present like product, adopt RGB mode trace analysis, only need to observe many groups at a back picric acid marker color.Estimating more direct aspect the Animal Behavior Science, science, more accurate more.In biomedicine experiment, be with a wide range of applications.Be widely used in preclinical medicine, clinical medicine, the zoopery of multi-door subject such as preventive medicine.
Description of drawings
Fig. 1 is a concrete structure schematic diagram of the present utility model.Among the figure: 1, casing; 2, rotating camera; 3, guard; 4, netted crib; 5, light source; 6, island platform; 7, extend the body of rod; 8, water inlet pipe; 9, thermostatical water bath; 10, the water surface; 11, outlet pipe.
Embodiment
The utility model is described in further detail below in conjunction with drawings and the specific embodiments.
As shown in Figure 1, a kind of constant temperature sleep deprivation device that is used for comprehensive shooting observed and recorded muroid medical experiment, comprise that one fills the casing 1 of water, be provided with in the casing along casing 1 length direction four island platforms 6 in one line, that be higher than the water surface 10, the size of island platform 6 only allows rat to stand, each island platform can be changed according to the rat bodily form, as rat: 6.5cm, mouse: 5.5cm.Be extended with the body of rod 7 on casing 1 four angles, the body of rod 7 ends are provided with light source 5, and light source 5 can adopt incandescent lamp or electricity-saving lamp to be used to the continuous lighting of observing, making a video recording.
The center, upper edge of casing length direction or width is arranged with the rotating camera 2 that is connected with Computer signal, and these two rotating camera can comprehensively photograph the tested mouse on arbitrary island platform 6 in the casing 1; By the LCDs of calculator, but Real Time Observation laboratory animal region, and in this regional time of staying; The sleep deprivation behavioral aspect of animal under nature can be measured, a plurality of active situation of mouse on island platform 6 of being tried can be observed, analyze simultaneously.
Casing 1 is provided with guard 3, the guard below is arranged with two to the netted V-arrangement crib 4 of rat for food along the casing length direction, crib 4 is parallel with casing 1 width, and crib 4 length equate that with casing 1 width each crib is just for providing feeding by the mouse of being tried between two island platforms 6 of casing minor face.
Casing 1 one side bottoms are provided with delivery port UNICOM outlet pipe 11 under water; The casing opposite side top of this water outlet oral-lateral is provided with water inlet UNICOM water inlet pipe 8, outlet pipe, water inlet pipe are connected to the outer thermostatical water bath 9 of a casing and are used for the constant temperature and the circulation of water in the guard box, can avoid being tried mouse and fall into interference behaviors such as easily producing stress reaction in the water, influence is to being tried the accuracy of mouse sleep deprivation behavioral study.Thermostatical water bath is except that the temperature that keeps water, and the intelligence part of thermostatical water bath has an automatic timing unit directly to control the lighting hours of light source 5.

Claims (4)

1. a muroid sleep deprivation device that is used for medical experiment comprises that one fills the casing of water, is provided with the island platform that several are higher than the water surface in the casing, island platform size only allows to be tried mouse and stands, it is characterized in that be extended with the body of rod on described casing four angles, body of rod end is provided with light source; The center, upper edge of casing length direction or width is arranged with the rotating camera that is connected with Computer signal, can comprehensively photograph the mouse of being tried on the platform of the interior arbitrary island of casing; Described casing is provided with guard, and the guard below is provided with to being tried the netted V-arrangement crib of mouse for food.
2. the muroid sleep deprivation device that is used for medical experiment as claimed in claim 1 is characterized in that described casing one side bottom is provided with delivery port UNICOM outlet pipe under water; The casing opposite side top of this water outlet oral-lateral is provided with water inlet UNICOM water inlet pipe, and outlet pipe, water inlet pipe are connected to the outer thermostatical water bath of a casing.
3. the muroid sleep deprivation device that is used for medical experiment as claimed in claim 2 is characterized in that, described island platform is along the setting in one line of casing length direction, and each island platform can be changed according to being tried the mouse bodily form.
4. the muroid sleep deprivation device that is used for medical experiment as claimed in claim 3 is characterized in that, described netted V-arrangement crib is arranged on guard below between two island platforms along the casing width.
CN2010200205691U 2010-01-19 2010-01-19 Mouse sleep depriving device for medical experiment Expired - Fee Related CN201591058U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010200205691U CN201591058U (en) 2010-01-19 2010-01-19 Mouse sleep depriving device for medical experiment

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Application Number Priority Date Filing Date Title
CN2010200205691U CN201591058U (en) 2010-01-19 2010-01-19 Mouse sleep depriving device for medical experiment

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102919141A (en) * 2012-09-24 2013-02-13 中国航天员科研训练中心 Rat and mouse sleep interferometer
CN106577322A (en) * 2016-11-30 2017-04-26 中国中医科学院西苑医院 Multi-platform water environment sleep deprivation water tank and system for animals
CN107280771A (en) * 2016-03-31 2017-10-24 北京中医药大学 Simulate the life entity experimental provision under the length boat state of ocean
CN109169376A (en) * 2018-09-11 2019-01-11 湖北中医药大学 Deprive the experimental provision of mouse sleep
CN114698558A (en) * 2022-03-09 2022-07-05 河南中医药大学 Sleep deprivation squirrel cage device for electric shock rats and mice
CN115316293A (en) * 2022-07-12 2022-11-11 北京大学 Aseptic animal sleep deprives case

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102919141A (en) * 2012-09-24 2013-02-13 中国航天员科研训练中心 Rat and mouse sleep interferometer
CN102919141B (en) * 2012-09-24 2017-09-22 中国航天员科研训练中心 Big mice sleep interferometer
CN107280771A (en) * 2016-03-31 2017-10-24 北京中医药大学 Simulate the life entity experimental provision under the length boat state of ocean
CN107280771B (en) * 2016-03-31 2024-05-10 北京中医药大学 Life body experimental device for simulating ocean long-distance navigation state
CN106577322A (en) * 2016-11-30 2017-04-26 中国中医科学院西苑医院 Multi-platform water environment sleep deprivation water tank and system for animals
CN109169376A (en) * 2018-09-11 2019-01-11 湖北中医药大学 Deprive the experimental provision of mouse sleep
CN114698558A (en) * 2022-03-09 2022-07-05 河南中医药大学 Sleep deprivation squirrel cage device for electric shock rats and mice
CN115316293A (en) * 2022-07-12 2022-11-11 北京大学 Aseptic animal sleep deprives case
CN115316293B (en) * 2022-07-12 2023-10-17 北京大学 Aseptic animal sleep deprivation case

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C14 Grant of patent or utility model
GR01 Patent grant
C53 Correction of patent for invention or patent application
CB03 Change of inventor or designer information

Inventor after: Tie Ru

Inventor after: Liu Fange

Inventor after: Yu Jun

Inventor after: Zhang Xuece

Inventor after: Zhou Xingchun

Inventor after: Yang Fang

Inventor after: Chen Jiankang

Inventor after: Qu Ping

Inventor before: Tie Ru

Inventor before: Yu Jun

Inventor before: Zhang Xuece

Inventor before: Zhou Xingchun

Inventor before: Yang Fang

Inventor before: Chen Jiankang

Inventor before: Qu Ping

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: TIE RU YU JUN ZHANG XUECE ZHOU XINGCHUN YANG FANG CHEN JIANKANG QU PING TO: TIE RU LIU FANGE YU JUN ZHANG XUECE ZHOU XINGCHUN YANG FANG CHEN JIANKANG QU PING

C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100929

Termination date: 20110119