CN201524354U - Head neck positioning frame for different-machine PET/CT image fusion - Google Patents

Head neck positioning frame for different-machine PET/CT image fusion Download PDF

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Publication number
CN201524354U
CN201524354U CN2009201412291U CN200920141229U CN201524354U CN 201524354 U CN201524354 U CN 201524354U CN 2009201412291 U CN2009201412291 U CN 2009201412291U CN 200920141229 U CN200920141229 U CN 200920141229U CN 201524354 U CN201524354 U CN 201524354U
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image
plate
location
pet
fusion
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徐子海
廖福锡
陈超敏
胡赟
周凌宏
童蕾
夏邦传
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Abstract

The utility model provides a head neck positioning frame for different-machine PET/CT image fusion, characterized in that: a N shaped plastic circular hollow tube for filling the agent is embedded into positioning plates on the three surfaces of the frame and two ends of the hollow tube extend outside an opening plastic tube with a tube plug, and grids and scales are drawn on the left, upper and right positioning plates. The head neck positioning frame has the following advantages: definite character and easy realization of fusion automatic processing due to using the external character point extraction method. The frame has features of simple system operation, reasonable cost, being favorable for popularization and use of the different-machine fusion and increased head neck tumor radiation therapy effect.

Description

A kind of incidence positioning framework that is used for different machine PET/CT image co-registration
Technical field
This utility model relates to a kind of auxiliary facilities that is used for radiodiagnosis, treatment, is specifically related to a kind of incidence positioning framework that is used for different machine PET/CT image co-registration.
Background technology
Radiation therapy technology has experienced the several developmental stage of radiotherapy (IGRT) of common radiotherapy, stereotaxic radiosurgery (SRS), 3 dimensional conformal radiation therapy (3DCRT), Intensity Modulation Radiated Therapy (IMRT) (IMRT) and image guiding, the epoch of accurate radiotherapy have now been entered, accurate radiotherapy can farthest reduce the irradiation of tumor normal surrounding tissue, improve the exposure dose of tumor greatly, improve the local control rate of tumor.
The radiotherapy of tumor is the big field that Medical image fusion is used, and to delineate be the basis of assurance accurate treatment in the target area accurately.Along with the development of molecular image technology with popularize, can will dissect and the image of functioning cell molecule variation combine clinical diagnosis and the treatment of carrying out tumor.
PET, positron emission computerized tomography just, can show tumor biology the aspect characteristic.The PET imaging technique can provide human body metabolic function image, but PET signal noise ratio (snr) of image and spatial resolution are all very low, and the shown pathological changes hypermetabolism zone of image is difficult to dissect accurately the location.And the CT imaging is clear, spatial resolution is high, and good reference effect is played in the location that can be focus, but its demonstration to focus itself is poor.Therefore thereby the metabolic function image of PET and the anatomic image of CT can be merged the dissection location of realizing hypermetabolism zone in the PET image.
The fusion of PET image and CT image is divided into different machine and merges dual mode with machine.Although become the goldstandard of image co-registration application technology with the machine fusion image, can reach high-precision image co-registration, with machine image co-registration cost 20 times of different machine image co-registration cost.Comparatively speaking, different machine merges with low cost.Along with the exploitation of computer technology and more advanced image fusion software, the application space that different machine merges in clinical is more and more wide.
Different machine image co-registration is carried out the transmission of data by general DICOM form between the different operating station, adopt the mode of total digitalization, and information dropout is few, image alignment degree of accuracy height.The step of different machine image co-registration is roughly: feature extraction, the design error appraisal procedure handles to make the error minimum to view data, the view data after the conversion is carried out para-position and integrated display, analysis integrated data.Wherein technique of counterpoint is the key and the difficult point of image co-registration, depends on the extraction of characteristic point.Surface be for carry out fusion treatment special on two width of cloth images all visible body surface label.
The utility model content
This utility model purpose is to provide a kind of incidence positioning framework that is used for different machine PET/CT image co-registration.
This utility model is the improvement to the accurate CT scan positioner of a kind of radiotherapy, design philosophy derives from body CT scan locating rack and the incidence posting of using clinically at present, its structure is generally and is inverted u-shaped, about and offer the groove of Z type on three poly (methyl methacrylate) plates combining by the quadrate poly (methyl methacrylate) plate of three block lengths of top, the marking rod of Z type is inlayed in the inside, and the material of marking rod is respectively metallic aluminium and carbon fibre.Such structure can obtain nine gauge points clearly in the CT image.But then can't imaging in the PET image, so the location can only realize CT scan the time.
We have designed a kind of different machine image co-registration of 3 D positioning equipment-PET/CT incidence positioning framework of suitable accurate radiotherapy characteristics voluntarily, obtain the locating information of image according to the external label point, gather PET image and CT image, carry out image registration and fusion, solved the accurate orientation problem of tumor of head and neck in the radiotherapy preferably.
Owing to adopt same location bed and vacuum pad to fix, guarantee the same position of different time, so the position can not deviation when carrying out CT and PET scanning respectively for the positioning framework that requirement is used to scan.The design philosophy of the proposition PET/CT integral scanning positioning framework of applicant innovation thus.The marking rod that is about to the Z type of former CT scan frame changes hollow stem into by solid aluminum bar or carbon fibre bar, when CT scan, pour into general liquid (as copper-bath), still can obtain the CT image of nine gauge points clearly, and when this framework of application carries out the PET scanning of same position, in-site pouring PET developer (having radioactivity and decay) can obtain the PET image of nine index points of same home position.
Architectural feature is: the N that is inlaid with perfusion reagent in the location- plate 1,2,3 of three of frameworks moulds material circular hollow tubule 4, the opening plastics tubule 9 of the protruding band pipe close 5 in hollow tubule 4 two ends; A left side, on, portrayal grid and scale on the right location- plate 1,2,3.
Opening plastics tubule 9 is vertical with location-plate plate face.
The image that collects is carried out pretreatment: PET and the CT view data obtained are carried out processing such as denoising, enhancing and split image Feature Extraction respectively.
The registration of PET and CT image: after respectively PET image and CT image being carried out pretreatment, the process of image registration is sought a kind of spatial alternation exactly on floating image, make it and corresponding point on another width of cloth reference picture reach consistent on the space, just same anatomic points has identical locus on two matching images.Have only in two width of cloth images nine characteristic points (center of circle) grid deviation quadratic sum hour, this two width of cloth image is just thought the image of same anatomical position.
The fusion of registering images: after PET image and CT image carried out registration, carry out the fusion work of image: based on the image co-registration framework of wavelet transformation, the PET/CT image of at first treating fusion carried out wavelet decomposition according to generally; Then when selecting the image co-registration rule, characteristic according to the PET/CT image, two hypothesis are proposed: the one, the image after supposing to merge is answered the information that comprises the PET/CT image simultaneously as much as possible, and we carry out the fusion of low frequency coefficient subimage according to weighted-average method to the low frequency coefficient of small echo in view of the above.The 2nd, suppose that the dissection locating information of fused image is mainly provided by the CT image, and then carry out the fusion of high frequency subimage according to the geometric properties information (curvature flow) that the CT image provides.These two hypothesis are unified in the framework of variation and merge, and use variational approach at last and find the solution, the PET/CT image after merge.
Incidence positioning framework of the present utility model has following outstanding advantage and effect:
(1) adopt the surface point extracting method, feature is clear and definite, is easy to realize merging automatization and handles.
(2) system is simple to operate, and cost is reasonable, helps promoting the use of of different machine fusion.
(3) improved the radiocurable effect of tumor of head and neck.
Description of drawings
Fig. 1 is a kind of incidence CT scan posting design front view that is used for precise radiotherapy.
Fig. 2 is a kind of incidence CT scan posting design left view that is used for precise radiotherapy.
Fig. 3 is this incidence CT scan posting pictorial diagram.
Fig. 4 is newly-designed PET/CT scanning one posting design front view.
Fig. 5 is newly-designed PET/CT scanning one posting design left view.
Fig. 6 is the three-dimensional structure diagram of newly-designed PET/CT scanning one posting.
The specific embodiment
Below in conjunction with accompanying drawing and implementation column this utility model is done further detailed description.
Fig. 1 is the front view of the incidence posting of our a kind of radiotherapy accurate positioning device of developing voluntarily, and it mainly is made up of connecting plate 8 and upper plate 7, fixed knob 6, scanning posting.The scanning posting is made up of preceding ring, back ring, left location-plate 1, last location-plate 2, right location-plate 3, all adopts pmma material.Left and right, on all be embedded with the CT scan telltale mark bar 4 that diameter is 4mm in the location-plate, be N shape and arrange.Have groove and be used for headrest is installed in connecting plate, with four mounting screws this connecting plate is fixed on the vacuum pad location bed, use facial film fixedly upper and lower plates clamps facial film and will be connected with connecting plate after its molding.
Fig. 2 is the left view of the incidence posting of this radiotherapy accurate positioning device, and as shown in Figure 2, the upper end in the outside of left location-plate and back-end location all indicate scale, and unit is mm.Be carved with the grid of being made up of horizontal line and cross hairs in the central marker district, the netting twine spacing is 10mm.
Fig. 3 is based on the designed CT scan locating rack of Fig. 1 and Fig. 2 and the pictorial diagram of incidence posting.Both telltale mark baseboard materials are lucite, on poly (methyl methacrylate) plate by the N shape location notch hole of numerical control milling method precision machining.The label that is embedded in the CT scan locating rack is the special standard carbon fibre of an import cylinder straight-bar, and the label that is embedded in the incidence posting is a metallic aluminium cylinder straight-bar, and standard carbon fibre cylinder straight-bar and aluminum bar are for solid everywhere.
Fig. 4 is the newly-designed PET/CT scanning head front view of infrastructural frame outward, and the scanning posting is made up of preceding ring, back ring, left location-plate 1, last location-plate 2, right location-plate 3, all adopts pmma material.As shown in the figure, wherein the N shape marking rod of each face is 0.6cm by outer aperture, internal orifice dimension is that the plastics circular hollow tubule of 0.4cm is formed, be embedded in the square location-plate of three block lengths and (wherein go up the parallel long 33cm of poly (methyl methacrylate) plate of location-plate 2, wide 24cm, vertical left location-plate 1 in both sides and the long 33cm of right location-plate 3 poly (methyl methacrylate) plates, wide 25cm) on the transparent plexiglass plate in the groove of N shape, three poly (methyl methacrylate) plates combine the structure of a U font, on the poly (methyl methacrylate) plate of each face, all portrayed the coordinate scale grid, the long 34cm of whole framework, wide 30cm, high 27cm, framework inner width 25cm, high 25cm.
Fig. 5 is the left view of the outer infrastructural frame of newly-designed PET/CT scanning head, N in three 1 of frameworks, 2,3 the poly (methyl methacrylate) plate moulds the material marking rod and is made up of two parts, a part moulds material circular hollow tubule 4 for the N that is embedded in the poly (methyl methacrylate) plate, a part is opening plastics tubule 9 and pipe close 5 compositions that the length at the outer N shape labelling pipe two ends of poly (methyl methacrylate) plate is 5cm, and it is vertical with lucite location-plate plate face.The bottom is connecting plate 8 and upper plate 7, is used for fixing U font scanning posting, and both connect with fixed knob 6.
Fig. 6 is the three-dimensional structure diagram of the outer infrastructural frame of newly-designed PET/CT scanning head.
Using method:
1) focus location: preliminary definite knub position under simulated positioner, delineate labelling in patient's incidence relevant position.The vacuum pad location bed is placed on the CT scan bed, and adjusting level and position, the left and right sides are also fixing.To rest the head on and the facial film fixing head is installed in location bed top, again vacuum pad be put into.Patient's both hands are sidelong and are lain into vacuum pad.The softening back of facial film row facial film is fixed.Will note lower jaw and nose molding especially, its position sharp outline is to guarantee fractionation of radiation resetting key link accurately.Because the cervical region mobility is bigger, needs to strengthen the facial film constant intensity sometimes, can take the multilamellar facial film to fix.Patient's shoulder is following to be fixed with the vacuum pad evacuation, and notices guaranteeing that patient is enough comfortable to reduce the activity of health.
2) CT scan
At first carry out CT scan: when giving plastics labelling pipe perfusion copper-bath, open an end of vertical tubule earlier, carry out the air emptying, pour into then, and then the vertical tubule of the sealing other end, respectively three hollow labelling pipe is carried out the perfusion of copper-bath respectively, finish three copper-bath perfusions in the N shape flexible plastic marking rod in the poly (methyl methacrylate) plate.
The incidence posting is installed on the facial film fixing head,, can carries out the CT scan location between patient's facial film and the fixing head, carry out enough labellings so that after the resetting more accurately between vacuum pad and the location bed.Attention will obtain having 9 location dots clearly outside focus and head in the CT image.
3) PET scanning
Patient takes off a frame then, move to PET scanning center, carry out PET scanning: when giving plastics labelling pipe perfusion developing agent, open an end of vertical tubule earlier, carry out the air emptying, pour into then, and then the vertical tubule of the sealing other end, respectively three hollow labelling pipe is carried out the perfusion of developing agent respectively, finish three PET developing agent perfusions in the N shape flexible plastic marking rod in the poly (methyl methacrylate) plate.
The incidence posting is installed on the facial film fixing head once more, and, can carries out PET scanning location according to after carrying out resetting accurately at the labelling between patient's facial film and the fixing head, between vacuum pad and the location bed.Attention will obtain having 9 location dots clearly outside focus and head in the PET image.
4) PET image and CT image are carried out registration after, carry out the fusion of both images.
Utilize 9 accurate registrations of locating the dot center of circle, 9 location that obtains in dot and the PET image in the CT image, can find the same layer position of scanning rapidly, can effectively solve the error that the position difference causes in the different machine CT/PET scanning.

Claims (2)

1. incidence positioning framework that is used for different machine PET/CT image co-registration, comprise N type posting, preceding ring, back ring, left location-plate (1), go up location-plate (2), right location-plate (3) and bottom fixed board, it is characterized in that: the N that is inlaid with perfusion reagent in the location-plate (1) of three of frameworks, (2), (3) moulds material circular hollow tubule (4), the opening plastics tubule (9) of the protruding band pipe closes in hollow tubule (4) two ends (5); A left side, on, right location-plate (1), (2), (3) go up portrayal grid and scale.
2. the incidence positioning framework that is used for different machine PET/CT image co-registration according to claim 1 is characterized in that: opening plastics tubule (9) is vertical with location-plate plate face.
CN2009201412291U 2009-08-21 2009-08-21 Head neck positioning frame for different-machine PET/CT image fusion Expired - Fee Related CN201524354U (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102319071A (en) * 2011-09-20 2012-01-18 潘启强 The human body attitude evaluation system
CN103054607A (en) * 2013-02-01 2013-04-24 徐州医学院 CT/MRI (Computed Tomography/Magnetic Resonance Imaging) double-body position fusion device for radiation therapy
CN103083038A (en) * 2013-02-01 2013-05-08 徐州医学院 Computed tomography (CT) double-position automatic registration and fusion device
CN104117156A (en) * 2013-04-28 2014-10-29 上海联影医疗科技有限公司 Radiotherapy device
CN104523287A (en) * 2015-01-12 2015-04-22 天津医科大学第二医院 Stereoscopic orientation frame for PET, CT and MR image fusion of head and neck range
CN104849123A (en) * 2015-06-10 2015-08-19 孟雪 Isolated tumor fixing device and method for producing pathological section by utilizing same
CN107595411A (en) * 2017-10-26 2018-01-19 安徽紫薇帝星数字科技有限公司 A kind of body surface locating system for being accurately positioned head
TWI625115B (en) * 2016-11-11 2018-06-01 安克生醫股份有限公司 Positioning apparatus for head and neck assessment or intervention

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102319071A (en) * 2011-09-20 2012-01-18 潘启强 The human body attitude evaluation system
CN103054607A (en) * 2013-02-01 2013-04-24 徐州医学院 CT/MRI (Computed Tomography/Magnetic Resonance Imaging) double-body position fusion device for radiation therapy
CN103083038A (en) * 2013-02-01 2013-05-08 徐州医学院 Computed tomography (CT) double-position automatic registration and fusion device
CN104117156A (en) * 2013-04-28 2014-10-29 上海联影医疗科技有限公司 Radiotherapy device
CN104523287A (en) * 2015-01-12 2015-04-22 天津医科大学第二医院 Stereoscopic orientation frame for PET, CT and MR image fusion of head and neck range
CN104849123A (en) * 2015-06-10 2015-08-19 孟雪 Isolated tumor fixing device and method for producing pathological section by utilizing same
CN104849123B (en) * 2015-06-10 2017-10-31 孟雪 Ex vivo Tumor fixing device and the method that pathological section is made using the device
TWI625115B (en) * 2016-11-11 2018-06-01 安克生醫股份有限公司 Positioning apparatus for head and neck assessment or intervention
CN107595411A (en) * 2017-10-26 2018-01-19 安徽紫薇帝星数字科技有限公司 A kind of body surface locating system for being accurately positioned head

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Granted publication date: 20100714

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