CN201519191U - Freeze melting device with independent pre-cooling device - Google Patents
Freeze melting device with independent pre-cooling device Download PDFInfo
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- CN201519191U CN201519191U CN2009202692798U CN200920269279U CN201519191U CN 201519191 U CN201519191 U CN 201519191U CN 2009202692798 U CN2009202692798 U CN 2009202692798U CN 200920269279 U CN200920269279 U CN 200920269279U CN 201519191 U CN201519191 U CN 201519191U
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- electromagnetic valve
- cooler
- air inlet
- pipeline
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Abstract
The utility model relates to a freeze melting device with an independent pre-cooling device. A high pressure gas inlet pipeline is connected with a gas heat exchanger of the pre-cooling device via a gas inlet electromagnetic valve; output is divided into two paths and connected with a heating gas inlet pipeline and a refrigerating gas inlet pipeline respectively via a heating electromagnetic valve and a refrigerating electromagnetic valve; output of a semi-conductor refrigerating plate of the pre-cooling device is connected with a low pressure gas returning pipeline; the refrigerating gas inlet pipeline, the heating gas inlet pipeline, the low pressure gas returning pipeline and a thermoelectric couple are coaxially placed inside a heat preservation sleeve; thermoelectric signals of the thermoelectric couple are inputted into a microcomputer via a temperature signal acquisition module; and the microcomputer outputs control signals after acquiring the temperature signals to control the pre-cooling device, a gas inlet electromagnetic valve, the heating electromagnetic valve and the refrigerating electromagnetic valve via an electromagnetic valve controller. The freeze melting device solves the technical problem of fast pre-cooling before gas throttling and refrigerating and gas rapid rewarming after gas freezing and melting, and has the advantages of convenient operation and carrying, simple structure, small and exquisite devices and low manufacturing.
Description
Technical field
This utility model relates to a kind of tumor micro-wound treatment technology, particularly a kind of cryoablation device with independent pre-cooler.
Background technology
The tumor micro-wound treatment is just becoming the forward position of contemporary clinical medicine development.Cryoablation is in the tumor micro-wound treatment one of technology of meaning represent to be arranged relatively, and mainly by cryosurgery tool, what control was arranged makes that lesion tissue experience is lowered the temperature, freezed, the rewarming process, thereby causes the irreversible damage even the necrosis of cell.Cryoablation to the kill mechanism of tumor is: cell dehydration and shrinkage; The mechanical damage of ice crystal formation and ice crystal in the cell; Cell electrolyte toxicity concentrates and pH value changes; The degeneration of cell membrane lipid protein ingredient; Blood stagnation and microthrombusis; Immunological effect etc.Cryoablation not only operation wound is little, and has advantages such as analgesia, post-operative complication are few, preventing tumor diffusion, is subjected to numerous doctors and patient's favorable comment deeply.
The Cryoablation system that has come out at present mainly is divided into two big classes: a class is the liquid nitrogen system cryoprobe, and the principle that need absorb a large amount of latent heats of vaporization when utilizing material to become gas by liquid makes tissue cooling rapidly; Another kind of is gas throttling system cryoprobe, and when gases at high pressure were flowed through the aperture adiabatic throttling, along with the decline of pressure, temperature tended to change, and that utilizes that the adiabatic throttling effect of gas can finish cryoablation falls the rewarming therapeutic process.The shortcoming of liquid nitrogen system cryoprobe has: the cutter head cooling rate is slower, is unfavorable for killing of tumor cell; The cryoprobe diameter is bigger, is unfavorable for minimally-invasive treatment; Equipment volume is huger, is not easy to transportation.Gas throttling system cryoprobe is the main flow of present clinical practice, and employed throttle air mainly contains argon and helium, nitrogen, mixed working fluid etc.Argon helium knife uses argon throttling cooling, and helium heats up, and has advantages such as device small volume and less weight, the heating and cooling of cryoprobe head are rapid, but the argon operating pressure is up to 40MPa, be difficult for to obtain, have certain potential safety hazard, and argon, helium be rare gas, the operation cost is higher.Use nitrogen throttle system operating pressure lower, but if will make cryoprobe reach the treatment temperature, must be to nitrogen precooled.Nitrogen precooled device generally adopts auto-cascading refrigeration system, and system bulk is big, high, the pre-cool time of work noise is long, is unfavorable for carrying and operation technique.The mixed work medium for throttling cryoprobe generally uses closed system, and refrigerating efficiency is higher, just can make working medium liquefaction under low operating pressure operating mode, but closed system cryoprobe cutter head dismounting inconvenience, need sterilization to reuse, the end of a period cryogenic temperature is higher, the further clinical verification that awaits of concrete therapeutic effect.
Summary of the invention
This utility model is at the deficiencies in the prior art problem, a kind of cryoablation device with independent pre-cooler has been proposed, have independently pre-cooler, solve before the gas throttling refrigeration technical problem of gas rapid rewarming behind the fast precooling and cryoablation simultaneously.
The technical solution of the utility model is: a kind of cryoablation device with independent pre-cooler, comprise pre-cooler, cryoprobe, gas transmission ﹠ distribution and control system, temperature measurement and control instrument, described gas transmission ﹠ distribution and control system by the high pressure admission pipeline, the refrigeration air inlet pipeline, heating air inlet pipeline, low pressure return line, air inlet electromagnetic valve, add thermoelectrical magnetic valve, the refrigeration electromagnetic valve constitute; Cryoprobe is made of spiral tube fin regenerator, J-T groove, thermal insulation casing; Temperature measurement and control instrument is the built-in thermocouple of cryoprobe, temperature signal collection module, microcomputer, solenoid valve controller; Pre-cooler is made up of radiator fan, fin, semiconductor chilling plate, gas heat-exchanger, the pre-cooler structure is symmetry up and down, two smooth circular face of gas heat-exchanger are closely pasted mutually with the cold junction of semiconductor chilling plate, fin is equipped with in the hot junction of semiconductor chilling plate, and fin foreign side is a radiator fan; The high pressure admission pipeline connects the gas heat-exchanger of pre-cooler by the air inlet electromagnetic valve, output divides two-way respectively by adding thermoelectrical magnetic valve, the refrigeration electromagnetic valve connects heating air inlet pipeline and refrigeration air inlet pipeline, the semiconductor chilling plate output of pre-cooler connects the low pressure return line, the refrigeration air inlet pipeline, the heating air inlet pipeline, the low pressure return line, thermocouple is coaxial to be positioned in the thermal insulation casing, the pyroelectric signal of thermocouple is through temperature signal collection module input microcomputer, microcomputer is exported control signal after collecting temperature signal, through solenoid valve controller to pre-cooler, the air inlet electromagnetic valve, adding thermoelectrical magnetic valve controls with the refrigeration electromagnetic valve.
Described gas heat-exchanger is made of annealing wrought copper pipe, turnover air pipe two-wire and around the mosquito incense shape, each pipeline closely pastes mutually, with scolding tin fixed gas heat exchanger, and the slit between the filling pipeline, the heat exchange contact surface of gas heat-exchanger and semiconductor chilling plate is smooth smooth.
Described semiconductor chilling plate can be in series by level semiconductor cooling piece or multi-disc semiconductor chilling plate.
The beneficial effects of the utility model are: the utlity model has the cryoablation device of independent pre-cooler, have independently pre-cooler, can reduce the operating pressure of gas, the temperature of quickening cryoprobe reduces; Mosquito incense shape gas heat-exchanger, volume is little, heat exchange efficiency is high; Have the active rewarming function, help extracting tumor after cryoprobe melts; The output of cryoprobe refrigerating capacity is controlled, the heating and cooling response speed is fast, cryoablation scope control accuracy height; The low pressure return line is discharged gas and is heated through fin, discharges not condensation, white with fixed attention of gas, therapy system refrigerating efficiency height; Easy to operate; Easy to carry; Simple in structure, the device small and exquisite, cheap.
Description of drawings
Fig. 1 is the structural representation that the utlity model has the cryoablation device of independent pre-cooler;
Fig. 2 is the structural representation that the utlity model has the gas heat-exchanger in the cryoablation device of independent pre-cooler;
Fig. 3 is the cross-sectional view that the utlity model has the pre-cooler in the cryoablation device of independent pre-cooler;
Fig. 4 is the structural representation that the utlity model has the cryoprobe in the cryoablation device of independent pre-cooler.
The specific embodiment
As shown in Figure 1, the cryoablation device with independent pre-cooler of the present utility model comprises high pressure admission pipeline 1, air inlet electromagnetic valve 2, pre-cooler 3 adds thermoelectrical magnetic valve 4, refrigeration electromagnetic valve 5, refrigeration air inlet pipeline 6, heating air inlet pipeline 7, thermal insulation casing 8, cryoprobe 9, low pressure return line 10, thermocouple 11, temperature signal collection module 12, microcomputer 13, solenoid valve controller 14.
As shown in Figure 2, gas heat-exchanger 3-4 makes of the annealing wrought copper pipe of easy heat conduction, extension good bandability, turnover air pipe two-wire and around if the mosquito incense shape, each pipeline closely pastes mutually, use the scolding tin stationary heat exchangers, and the slit between the filling pipeline, two circular face of polishing heat exchanger make the heat exchange contact surface of heat exchanger and semiconductor chilling plate smooth smooth.
As shown in Figure 3, form by radiator fan 3-1, fin 3-2, semiconductor chilling plate 3-3, gas heat-exchanger 3-4 etc.Pre-cooler is symmetry about in the of 3, and two smooth circular face of gas heat-exchanger 3-4 are closely pasted mutually with the cold junction of semiconductor chilling plate 3-3, and fin 3-2 is equipped with in the hot junction of semiconductor chilling plate 3-3, and fin 3-2 top is radiator fan 3-1.When semiconductor chilling plate 3-3 brought into operation, radiator fan 3-1 action made the air forced convection, helped fin 3-2 heat radiation.
As shown in Figure 4, cryoprobe 9 is made of spiral tube fin regenerator 9-1, J-T groove 9-2 etc.Refrigeration air inlet pipeline 6 is connected with spiral tube fin regenerator 9-1, the other end of spiral tube fin regenerator 9-1 connects J-T groove 9-2, place thermocouple on the J-T groove 9-2 limit in the cryoprobe 9, be used to monitor the temperature in the cryoprobe 9, refrigeration air inlet pipeline 6, heating air inlet pipeline 7, low pressure return line 10, thermocouple 11 coaxial being positioned in the thermal insulation casing 8.
When carrying out cold therapy, freeze behind the dc source of connection semiconductor chilling plate 3-3, microcomputer 13 sends a signal to solenoid valve controller 14, open air inlet electromagnetic valve 2, refrigeration electromagnetic valve 5, close and add thermoelectrical magnetic valve 4, normal temperature high voltage gas flows into from high pressure admission pipeline 1, in gas heat-exchanger 3-4 after the pre-cooling, through refrigeration air inlet pipeline 6, spiral tube fin regenerator 9-1 enters J-T groove 9-2 throttling blood pressure lowering refrigeration, gas after the throttling flows through spiral tube fin regenerator 9-1 fin rear flank and enters low pressure return line 10, utilize the cryogenic gas cooling high-pressure side gas temperature after the throttling, make the gas can throttling under the situation lower than initial temperature, obtain temperature after the lower throttling, last gas flows out from the several rows of aperture of low pressure return line 10 ends, and cold sink 3-2 makes semiconductor chilling plate 3-3 cold junction temperature lower, obtains lower precooling temperature, effluent air temp is increased to more than the condensation temperature, enters in the environment.So constantly go on, the temperature of gas is more and more lower, and the treatment that reaches cryoablation until balance requires temperature.
Can show the ice hockey size that cryoprobe 9 generates by ultrasonic or MMR, when the size covering cryoablation target area of ice hockey scope, and thermocouple 11 reaches setting value through cryoprobe 9 tool temperature that temperature signal collection module 12 feeds back to microcomputer 13, for avoiding the excessive cold injury normal structure of ablation range, strengthening cryoablation target area tumor cytotoxicity effect, it is constant to need to keep cryoprobe 9 to generate the ice hockey size, cryoablation district constant temperature a period of time.Microcomputer 13 sends a signal to solenoid valve controller 14, controls the switching of air inlet electromagnetic valve 2 by the mode of regulating dutycycle, makes the output refrigerating capacity of cryoprobe 9 can be 0～100% free adjustment, the growth of may command ice hockey size or keep the ice hockey size constant.
Cryoablation once might not thoroughly kill the tumor cell of target area, and the heating and cooling repeatedly of several cycles can improve the death of neoplastic cells rate, reduces tumor local recur and leads.Cryoablation district rewarming divides nature rewarming, two kinds.When carrying out cryoablation district active rewarming, the cold and hot end of cooling piece exchanges behind the dc source both positive and negative polarity of reversal connection semiconductor chilling plate 3-3, microcomputer 13 sends a signal to solenoid valve controller 14, open air inlet electromagnetic valve 2, add thermoelectrical magnetic valve 4, close refrigeration electromagnetic valve 5, normal temperature high voltage gas flows into from high pressure admission pipeline 1, after in gas heat-exchanger 3-4, heating, gas after the heating enters cryoprobe 9 through heating air inlet pipeline 7, the heats cold jet blade, last gas flows out in the several rows of aperture of low pressure return line 10 ends, enters in the environment.
The utlity model has independently pre-cooler, have the active rewarming function, the characteristics such as controlled, the heating and cooling fast response time of cryoprobe refrigerating capacity output has cryoablation scope control precision height, small and exquisite, cheap, simple to operate, and is easy to carry. Can be widely used in the freezing assist location of cryoablation treatment or the total surgical resection of multiple innocent and malignant tumour.
Claims (3)
1. cryoablation device with independent pre-cooler, comprise pre-cooler (3), cryoprobe (9), gas transmission ﹠ distribution and control system, temperature measurement and control instrument, it is characterized in that, described gas transmission ﹠ distribution and control system by high pressure admission pipeline (1), refrigeration air inlet pipeline (6), heating air inlet pipeline (7), low pressure return line (10), air inlet electromagnetic valve (2), add thermoelectrical magnetic valve (4), refrigeration electromagnetic valve (5) constitutes; Cryoprobe (9) is made of spiral tube fin regenerator (9-1), J-T groove (9-2), thermal insulation casing (8); Temperature measurement and control instrument is the built-in thermocouple of cryoprobe (11), temperature signal collection module (12), microcomputer (13), solenoid valve controller (14); Pre-cooler (3) is made up of radiator fan (3-1), fin (3-2), semiconductor chilling plate (3-3), gas heat-exchanger (3-4), pre-cooler (3) structure is symmetry up and down, two smooth circular face of gas heat-exchanger (3-4) are closely pasted mutually with the cold junction of semiconductor chilling plate (3-3), fin (3-2) is equipped with in the hot junction of semiconductor chilling plate (3-3), and fin (3-2) foreign side is radiator fan (3-1); High pressure admission pipeline (1) connects the gas heat-exchanger (3-4) of pre-cooler (3) by air inlet electromagnetic valve (2), output divides two-way respectively by adding thermoelectrical magnetic valve (4), refrigeration electromagnetic valve (5) connects heating air inlet pipeline (7) and refrigeration air inlet pipeline (6), semiconductor chilling plate (3-3) output of pre-cooler (3) connects low pressure return line (10), refrigeration air inlet pipeline (6), heating air inlet pipeline (7), low pressure return line (10), thermocouple (11) is coaxial to be positioned in the thermal insulation casing, the pyroelectric signal of thermocouple (11) is through temperature signal collection module (12) input microcomputer (13), export control signal after microcomputer (13) collects temperature signal, through solenoid valve controller (14) to pre-cooler (3), air inlet electromagnetic valve (2), adding thermoelectrical magnetic valve (4) controls with refrigeration electromagnetic valve (5).
2. the cryoablation device with independent pre-cooler according to claim 1, it is characterized in that, described gas heat-exchanger (3-4) is made of annealing wrought copper pipe, turnover air pipe two-wire and around the mosquito incense shape, each pipeline closely pastes mutually, with scolding tin fixed gas heat exchanger (3-4), and the slit between the filling pipeline, gas heat-exchanger (3-4) is smooth smooth with the heat exchange contact surface of semiconductor chilling plate (3-3).
3. the cryoablation device with independent pre-cooler according to claim 1 is characterized in that, described semiconductor chilling plate (3-3) can be in series by single-stage semiconductor chilling plate or multi-disc semiconductor chilling plate.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009202692798U CN201519191U (en) | 2009-11-10 | 2009-11-10 | Freeze melting device with independent pre-cooling device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009202692798U CN201519191U (en) | 2009-11-10 | 2009-11-10 | Freeze melting device with independent pre-cooling device |
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| CN201519191U true CN201519191U (en) | 2010-07-07 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732090B (en) * | 2009-11-10 | 2011-05-04 | 上海理工大学 | Cryoablation system with precooling device and control method thereof |
| CN105708541A (en) * | 2016-04-11 | 2016-06-29 | 赵国江 | Control method for throttling freezing type cryosurgery device |
| CN105902310A (en) * | 2016-04-11 | 2016-08-31 | 赵国江 | Cryosurgery device capable of achieving freezing and rewarming by adjusting gas pressure |
| CN106901828A (en) * | 2017-02-22 | 2017-06-30 | 上海导向医疗系统有限公司 | The cryoprobe for cryoablation method treating cancer containing Graphene |
| CN107714172A (en) * | 2017-11-10 | 2018-02-23 | 上海导向医疗系统有限公司 | Thermometric and the cryoablation pin of rewarming function are realized by thermocouple wire simultaneously |
| CN108036995A (en) * | 2018-01-16 | 2018-05-15 | 南京大学 | A kind of smell booster based on pre-concentration principle |
-
2009
- 2009-11-10 CN CN2009202692798U patent/CN201519191U/en not_active Expired - Lifetime
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732090B (en) * | 2009-11-10 | 2011-05-04 | 上海理工大学 | Cryoablation system with precooling device and control method thereof |
| CN105708541A (en) * | 2016-04-11 | 2016-06-29 | 赵国江 | Control method for throttling freezing type cryosurgery device |
| CN105902310A (en) * | 2016-04-11 | 2016-08-31 | 赵国江 | Cryosurgery device capable of achieving freezing and rewarming by adjusting gas pressure |
| CN105902310B (en) * | 2016-04-11 | 2018-07-06 | 天津美电医疗科技有限公司 | Cryosurgery device for adjusting air pressure to realize freezing and rewarming |
| CN106901828A (en) * | 2017-02-22 | 2017-06-30 | 上海导向医疗系统有限公司 | The cryoprobe for cryoablation method treating cancer containing Graphene |
| CN107714172A (en) * | 2017-11-10 | 2018-02-23 | 上海导向医疗系统有限公司 | Thermometric and the cryoablation pin of rewarming function are realized by thermocouple wire simultaneously |
| CN108036995A (en) * | 2018-01-16 | 2018-05-15 | 南京大学 | A kind of smell booster based on pre-concentration principle |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20100707 Effective date of abandoning: 20091110 |