CN201500106U - Electric field generating device for rapidly pacemaking myocardial cells - Google Patents

Electric field generating device for rapidly pacemaking myocardial cells Download PDF

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Publication number
CN201500106U
CN201500106U CN200920127895XU CN200920127895U CN201500106U CN 201500106 U CN201500106 U CN 201500106U CN 200920127895X U CN200920127895X U CN 200920127895XU CN 200920127895 U CN200920127895 U CN 200920127895U CN 201500106 U CN201500106 U CN 201500106U
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CN
China
Prior art keywords
electric field
generating device
electrode plate
lead plate
field generating
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200920127895XU
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Chinese (zh)
Inventor
程伟
肖颖彬
王伟
严健
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Second Affiliated Hospital of TMMU
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Second Affiliated Hospital of TMMU
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Priority to CN200920127895XU priority Critical patent/CN201500106U/en
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Abstract

The utility model provides an electric field generating device for rapidly pacemaking myocardial cells. The electric field generating device comprises a first electrode plate and a second electrode plate which are arranged oppositely parallelly, and further comprises a support for mounting the first electrode plate and the second electrode plate; a sliding groove and a limit clamp are used for adjusting up and down parallel movement of the electrode plates and arranged on the support; and the first electrode plate and the second electrode plate are respectively connected with a positive electrode and a negative electrode of a variable power source through conducting wires. The electric field generating device can match with an incubator in use, keep liveness of the myocardial cells in a biotic environment inside a simulated animal, acquire experimental data of changes of the myocardial cells after the action of electric field with different frequency and different time, and study and analyze the experimental data so as to facilitate research of high-speed arrhythmia. The electric field generating device has the advantages of simple structure, small volume, low cost and convenient control.

Description

The electric field generation device of rapid pacing myocardial cell
Technical field
This utility model relates to a kind of medical use experimental facilities, is specifically related to a kind of rapid pacing device of myocardial cell under electric field action that be used to study.
Background technology
Medical circle in the basic research of carrying out tachy-arrhythmia, normally utilizes animal model to experimentize.For example,, and give the electricity irritation of certain intensity and frequency at the animal hearts implant electrode, the cardiac pacing data when writing down varying strength and frequency effect again, and carry out research and analysis with this.But, in zoopery certain limitation is arranged, such as can't accurately intervene, the influence factor is numerous and ethnics Problem etc.Along with the maturation of myocardial cell culture technique and perfect, former generation cardiac muscle cells can be used as myocardial model and carry out the research of heart disease pathophysiology.The model that utilizes cultured cell to set up can carry out the research of longer time, in vitro study can reduce or avoid the influence of body intrinsic factor to result of study for a long time, utilize Protocols in Molecular Biology, can study the protein expression situation of simple myocardial cell, because the maturation of cell storing technology, utilize the cultivation myocardial cell to study and can save time and money, the direct reliable results of on atrial muscle cell, studying, the cell model of setting up rapid pacing is of great importance.Thereby the myocardial cell model of research rapid pacing becomes those skilled in the art's research focus, still, does not still have the device of the direct rapid pacing myocardial cell of perfect energy at present both at home and abroad.
The utility model content
At the prior art above shortcomings, the purpose of this utility model is to provide a kind of experimental data stable, reliable, directly the device of rapid pacing myocardial cell.
The purpose of this utility model is achieved in that a kind of electric field generation device of rapid pacing myocardial cell, first battery lead plate that comprises opposing parallel and establish and second battery lead plate, it is characterized in that, also comprise the support that described first battery lead plate and second battery lead plate are installed, support is provided with regulates upper and lower parallel mobile chute of described battery lead plate and spacing card; Described first battery lead plate and second battery lead plate are connected the positive and negative electrode of variable power supply respectively by lead.
Employing the utlity model has following advantage: this pacemaker utilizes electromagnetic field that myocardial cell is carried out rapid pacing, by the electric field action that on electrode, produces, can carry out real time record to the reaction of myocardial cell under different condition, and obtain the data of pace-making by the reaction of myocardial cell, precision is higher, be difficult for being affected by the external environment good reliability; Simultaneously can effectively control pacing frequency, intensity and time, reach and the identical effect of animal model (promptly directly on the animal body heart, adorn the pace-making lead and carry out pace-making); And, have simple in structure, volume is little, cost is low and control characteristics easily.Can conveniently insert incubator, guarantee to implement medical experiment under certain environmental conditions, control is convenient, flexible, helps the extensive popularization in medical research.
Description of drawings
Fig. 1 is a structural representation of the present utility model.
The specific embodiment
The utility model is described in further detail below in conjunction with the drawings and specific embodiments.
As shown in Figure 1, a kind of electric field generation device of rapid pacing myocardial cell, first battery lead plate 1 that comprises opposing parallel and establish and second battery lead plate 2, also comprise the support 3 that described first battery lead plate 1 and second battery lead plate 2 are installed, support 3 is provided with regulates upper and lower parallel mobile chute 4 of described first, second battery lead plate and spacing card 5; Described first battery lead plate 1 and second battery lead plate 2 are connected the positive and negative electrode of variable power supply 6 respectively by lead.Described first battery lead plate 1, second battery lead plate 2 and support 3 all can be located in the shell 7.Variable power supply 6 can provide needed current intensity and frequency range (as BL-420E +The biological function experimental system), can guarantee that the alternating electric field frequency that the electric field generation device of this rapid pacing myocardial cell produces is 400Hz-600Hz.The spacing of described first battery lead plate 1 and second battery lead plate 2 is adjustable in 5cm-15cm (please revise) scope, applicable to different occasions.
This utility model can cooperate incubator to use, and makes myocardial cell under the intravital biotic environment of simulated animal, to have kept the activity of myocardial cell.Make the electric field generation device of rapid pacing myocardial cell produce the variable electric field of 400Hz-600Hz by the switch of regulating variable power supply 6, under the stimulation of different time (as 48-72 hour), obtain the experimental data that the myocardial cell through different frequency and different time electric field action changes, resulting data are accurate, make the experimental reliability of cardiac pacing improve, carry out research and analysis with this, be beneficial to follow-up research.Use this utility model good stability, easy to operate, control method is simple, helps the extensive popularization in medical research.Because single unit system is simple in structure, volume is less, thereby cost is lower.

Claims (2)

1. the electric field generation device of rapid pacing myocardial cell, first battery lead plate (1) that comprises opposing parallel and establish and second battery lead plate (2), it is characterized in that, also comprise the support (3) that described first battery lead plate (1) and second battery lead plate (2) are installed, support (3) is provided with regulates upper and lower parallel mobile chute of described battery lead plate (4) and spacing card (5); Described first battery lead plate (1) and second battery lead plate (2) are connected the positive and negative electrode of variable power supply (6) respectively by lead.
2. the electric field generation device of rapid pacing myocardial cell according to claim 1 is characterized in that, the spacing of described first battery lead plate (1) and second battery lead plate (2) is 5cm-15cm.
CN200920127895XU 2009-07-02 2009-07-02 Electric field generating device for rapidly pacemaking myocardial cells Expired - Fee Related CN201500106U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200920127895XU CN201500106U (en) 2009-07-02 2009-07-02 Electric field generating device for rapidly pacemaking myocardial cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN200920127895XU CN201500106U (en) 2009-07-02 2009-07-02 Electric field generating device for rapidly pacemaking myocardial cells

Publications (1)

Publication Number Publication Date
CN201500106U true CN201500106U (en) 2010-06-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200920127895XU Expired - Fee Related CN201500106U (en) 2009-07-02 2009-07-02 Electric field generating device for rapidly pacemaking myocardial cells

Country Status (1)

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CN (1) CN201500106U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110042059A (en) * 2019-06-04 2019-07-23 中山大学 Cell electric microfield bringing device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110042059A (en) * 2019-06-04 2019-07-23 中山大学 Cell electric microfield bringing device

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GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100609

Termination date: 20110702