CN205411950U - Combine magnetic field and supersound production vector nature not to have device of creating focus electro photoluminescence - Google Patents
Combine magnetic field and supersound production vector nature not to have device of creating focus electro photoluminescence Download PDFInfo
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- CN205411950U CN205411950U CN201520983038.5U CN201520983038U CN205411950U CN 205411950 U CN205411950 U CN 205411950U CN 201520983038 U CN201520983038 U CN 201520983038U CN 205411950 U CN205411950 U CN 205411950U
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- magnetic field
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- 238000005424 photoluminescence Methods 0.000 title abstract 3
- 238000012544 monitoring process Methods 0.000 claims abstract description 18
- 230000005284 excitation Effects 0.000 claims abstract description 14
- 238000013519 translation Methods 0.000 claims abstract description 14
- 230000033228 biological regulation Effects 0.000 claims abstract description 6
- 230000009471 action Effects 0.000 claims description 21
- 230000005611 electricity Effects 0.000 claims description 21
- 230000007794 irritation Effects 0.000 claims description 20
- 230000006698 induction Effects 0.000 claims description 16
- 238000002604 ultrasonography Methods 0.000 claims description 16
- 230000005540 biological transmission Effects 0.000 claims description 8
- 230000000694 effects Effects 0.000 claims description 4
- 238000006243 chemical reaction Methods 0.000 claims description 3
- 230000004936 stimulating effect Effects 0.000 abstract 2
- 230000005684 electric field Effects 0.000 description 12
- 210000001519 tissue Anatomy 0.000 description 6
- 230000007383 nerve stimulation Effects 0.000 description 3
- 238000004088 simulation Methods 0.000 description 3
- 230000008685 targeting Effects 0.000 description 3
- 230000001537 neural effect Effects 0.000 description 2
- 210000001178 neural stem cell Anatomy 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 229910001112 rose gold Inorganic materials 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 229920005479 Lucite® Polymers 0.000 description 1
- 240000001439 Opuntia Species 0.000 description 1
- 239000007822 coupling agent Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000004126 nerve fiber Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 210000004003 subcutaneous fat Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
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Abstract
The utility model provides a combine magnetic field and supersound production vector nature not to have device of creating focus electro photoluminescence, including: the setting is used for producing the supersound excitation and applys the supersound stimulating module on the sample in one side of sample, sets up to be used for producing magnetic field and to apply the magnetic field of monitoring the intensity of overflow tank in magnetic field on the sample simultaneously taking place and monitoring module in the upper end of sample for realize the fixed of the fixed of supersound stimulating module and accurate translation and sample and rotation regulation's fixing device. The utility model discloses a combine magnetic field and supersound production vector nature not to have device of creating focus electro photoluminescence, the intensity of overflow tank in magnetic field, supersound impulse waveform and pulse amplitude are adjusted to the accessible to and the focus position, realize organizing the nervous accurate target of sample amazing, the amazing precision of improvement realizes not having the higher target of creating that has and fixes a position the characteristic.
Description
Technical field
This utility model relates to a kind of nerve stimulation device.Particularly relate to one and utilize focus ultrasonic characteristic combined magnetic field, can penetrator table organization, nervous tissue inside is realized noinvasive precise positioning stimulate combined magnetic field and ultrasonic generation vector property noinvasive focus on electricity irritation device.
Background technology
Nerve stimulation technique, for regulation neural activity, treats mental disorder, and tissue rehabilitation etc. has important Research Significance.Traditional electrical stimulus patterns, uses electrode to apply to stimulate, and the low conductivity of tissue surface, such as skin, subcutaneous fat, skull etc. makes electric current dispersion loss, stimulates inefficient, and therapeutic process can cause patient uncomfortable simultaneously.And the Neural stem cell mode being widely studied in recent years, it is to avoid the problems referred to above.But due to Neural stem cell mode, magnetic focusing have necessarily can difficulty, limit it and carry out precision positioning stimulation, this tissue nerve that would likely result in beyond target area to be treated is upset, and produces certain side effect.
Summary of the invention
Technical problem to be solved in the utility model is to provide a kind of device being capable of the noninvasive combined magnetic field with higher targeting locating features and the focusing electricity irritation of ultrasonic generation vector property noinvasive.
This utility model be the technical scheme is that a kind of combined magnetic field and ultrasonic generation vector property noinvasive focus on the device of electricity irritation, include: be arranged on the side of sample for producing ultrasonic action the ultrasonic action module putting on sample, it is arranged on the upper end of sample for producing magnetic field and putting on magnetic field generation and the monitoring modular of the magnetic induction monitoring magnetic field on sample, for realizing the fixing of ultrasonic action module and precision translation and the fixing device fixing and rotating regulation of sample simultaneously.
Described ultrasonic action module includes:
Ultrasound pulse transmission receptor, is used for producing ultrasonic excitation signal and receiving ultrasound echo signal；
Ultrasonic transducer, is fixed in described fixing device, is connected with described ultrasound pulse transmission receptor, for the excitation signal of telecommunication is converted into ultrasonic signal, and ultrasound echo signal is converted into voltage signal, it is achieved the energy conversion of voltage signal and ultrasonic signal；
Acoustic couplant, is arranged between described ultrasonic transducer and sample, for the ultrasonic signal that ultrasonic transducer produces is coupled to sample, reduces the decay of ultrasonic signal.
Described magnetic field occurs to include with monitoring modular:
Power supply, is used for exporting electric current；
Electric magnet, is arranged at above sample, connects power supply and is used for, according to different supply currents, producing the action of a magnetic field of different magnetic induction on sample；
Tesla meter, is arranged on the side of electric magnet, for realizing the monitoring in magnetic field, shows the magnetic induction in magnetic field in real time.
Described fixing device includes: base, and:
Accurate translation stage, is arranged on described base, is used for fixing ultrasonic transducer, it is achieved the accurate translation of ultrasonic transducer；
Turntable, it is possible to being arranged on described base of 360 degree of rotations；
Carrying disk, is fixed on above described turntable, for placing sample to be stimulated, and realizes 360 degree of rotations of sample under the effect of turntable.
The magnetic induction line direction, magnetic field that described magnetic field occurs with monitoring modular produces is vertical with the ultrasonic excitation signal direction of propagation that described ultrasonic action module produces, and magnetic induction line direction, described magnetic field is electricity irritation direction with the vector product direction of the ultrasonic excitation signal of generation.
Described sample to be stimulated is the nonisulated property sample having certain electric conductivity.
A kind of combined magnetic field of the present utility model and ultrasonic generation vector property noinvasive focus on the device of electricity irritation, can be by regulating the magnetic induction in magnetic field, ultrasonic pulse waveform and pulse amplitude, and focal position, realize the neural accurate targeting of tissue samples to stimulate, improve and stimulate precision, it is achieved noninvasive have higher targeting locating features.
Accompanying drawing explanation
Fig. 1 is the structural representation of the device of this utility model combined magnetic field and the focusing electricity irritation of ultrasonic generation vector property noinvasive；
In figure
1: ultrasonic action module 2: magnetic field occurs and monitoring modular
3: sample 4: fixing device
11: ultrasound pulse transmission receptor 12: ultrasonic transducer
13: acoustic couplant 21: power supply
22: electric magnet 23: Tesla meter
41: base 42: accurate translation stage
43: turntable 44: carrying disk
Fig. 2 a is transducer sound field normalized distribution in the axial direction；
Fig. 2 b is the distribution map of the electric field produced in the axial direction under the action of a magnetic field with Fig. 2 a same transducer；
Fig. 3 a is the sound-filed simulation figure in transducer lateral cross section at focal length；
Fig. 3 b is to produce the scattergram of electric field under the action of a magnetic field in lateral cross section at focal length with Fig. 3 a same transducer；
Fig. 4 a be sound field and electric field intensity are normalized after longitudinal center line on scattergram；
Fig. 4 b be sound field and electric field intensity are normalized after lateral cross section at focal length centrage on scattergram.
Detailed description of the invention
The device a kind of combined magnetic field of the present utility model and ultrasonic generation vector property noinvasive being focused on electricity irritation below in conjunction with embodiment and accompanying drawing is described in detail.
As shown in Figure 1, a kind of combined magnetic field of the present utility model and ultrasonic generation vector property noinvasive focus on the device of electricity irritation, include: be arranged on the side of sample 3 for producing ultrasonic action the ultrasonic action module 1 putting on sample 3, it is arranged on the upper end of sample 3 for producing magnetic field and putting on the magnetic field of the magnetic induction monitoring magnetic field on sample 3 and occur and monitoring modular 2 simultaneously, for realizing being motivated by ultrasound the fixing of the fixing and accurate translation of module 1 and sample 3 and rotating the fixing device 4 of regulation.
Described magnetic field occur with monitoring modular 2 produce magnetic induction line direction, magnetic field (such as z-axis direction in Fig. 1) with as described in ultrasonic action module 1 generation the ultrasonic excitation signal direction of propagation (such as x-axis direction in Fig. 1) vertical, magnetic induction line direction, described magnetic field is electricity irritation direction with the vector product direction (such as y-axis direction in Fig. 1) of the ultrasonic excitation signal of generation, nerve stimulation is realized, so the direction of electricity irritation can be needed to determine sample placement direction according to sample to be stimulated in the direction.
Described sample 3 to be stimulated is the nonisulated property sample having certain electric conductivity, such as electrolytes such as biological tissues.It is particularly suitable for the nerve fiber within organism is carried out vector stimulation.
Described ultrasonic action module 1 includes: ultrasound pulse transmission receptor 11, for producing ultrasonic excitation signal and receiving ultrasound echo signal, drive ultrasonic transducer, and the parameter such as wave-shape amplitude of output ultrasonic excitation signal can be regulated, described ultrasound pulse transmission receptor 11 can use the U.S. Panametrics5072PR or Panametrics5800PR to realize；Ultrasonic transducer 12, it is fixed in described fixing device 4, it is connected with described ultrasound pulse transmission receptor 11, for the excitation signal of telecommunication is converted into ultrasonic signal, reduce the decay of ultrasonic signal, and ultrasound echo signal is converted into voltage signal, it is achieved the energy conversion of voltage signal and ultrasonic signal, ultrasonic transducer 12 uses U.S. PanametricsV303SU or U.S. PanametricsV301 to realize；Acoustic couplant 13, it is arranged between described ultrasonic transducer 12 and sample 3, for the ultrasonic signal that ultrasonic transducer 12 produces is coupled to sample 3, reducing the decay of ultrasonic signal, described acoustic couplant 13 can use the M-250A ultrasonic coupling agent of Shenzhen OURABO or the M-200PA couplant of Shenzhen MIBO to realize.
Described magnetic field occurs to include with monitoring modular 2: power supply 21, is used for exporting electric current, and described power supply 21 can use Beijing state electricity Asia light HY-17 power supply or Changchun English general XD-30K power supply；Electric magnet 22, is arranged at above sample 3, connects power supply 21 and is used for according to different supply currents, and the action of a magnetic field of the different magnetic induction of generation is on sample 3, and described electric magnet 22 can use general SBV-300 or SBV-380 of Changchun English；Tesla meter 23, is arranged on the side of electric magnet 22, for realizing the monitoring in magnetic field, shows the magnetic induction in magnetic field in real time, and described Tesla meter 23 can use U.S. Lakeshore475, or in Qingdao, space ring safe 931 realizes.
Described fixing device 4 includes: base 41, and: accurate translation stage 42, it is arranged on described base 41, is used for fixing ultrasonic transducer 12, it is achieved the accurate translation of ultrasonic transducer 12；Turntable 43, it is possible to being arranged on described base 41 of 360 degree of rotations；Carrying disk 44, is fixed on above described turntable 43, for placing sample 3 to be stimulated, and realizes 360 degree of rotations of sample 3 under the effect of turntable 43.Wherein, described base 41 can use long 400mm, wide 250mm, and the lucite processing of thick 5mm realizes, and described carrying disk 44 can use diameter 200mm, the circular poly (methyl methacrylate) plate of thick 5mm to make.Described accurate translation stage 42 can use Shenzhen outstanding XY60-R precision translation stage of red gold or Beijing North light century PTS110 precision translation stage to realize.Described turntable 43 can use Shenzhen outstanding LS60-LM turntable of red gold or Beijing Pai Diwei PT-SD206 turntable to realize.Described turntable bottom is connected with base screw, and top is connected with carrying disk screw, can realize 360 degree and rotate regulation.
Utilize a kind of combined magnetic field of the present utility model and ultrasonic generation vector property noinvasive to focus on the preliminary experiment that the device of electricity irritation is carried out, measure the sound field and Electric Field Distribution result obtained as shown in Fig. 2 a, Fig. 2 b, Fig. 3 a, Fig. 3 b, Fig. 4 a, Fig. 4 b.Fig. 2 a is transducer sound field normalized distribution in the axial direction, and Fig. 2 b is the distribution map of the electric field that same transducer produces under the action of a magnetic field in the axial direction；Fig. 3 a is the sound-filed simulation figure in transducer lateral cross section at focal length, and Fig. 3 b is the scattergram producing electric field in same transducer lateral cross section under the action of a magnetic field at focal length；Fig. 4 a be sound field and electric field intensity are normalized after longitudinal center line on scattergram, Fig. 4 b be sound field and electric field intensity are normalized after lateral cross section at focal length centrage on scattergram.From result, the electric field that the device utilizing a kind of combined magnetic field of the present utility model to focus on electricity irritation with ultrasonic generation vector property noinvasive produces is consistent with the sound-filed simulation that ultrasonic transducer is launched.From Electric Field Distribution, for the electric field stimulated, within stimulated zone can focus on 2-3mm region, focusing is stimulated to significantly improve.
Claims (6)
1. a combined magnetic field and ultrasonic generation vector property noinvasive focus on the device of electricity irritation, it is characterized in that, include: the side being arranged on sample (3) is used for producing the ultrasonic action module (1) being motivated by ultrasound and putting on sample (3), the upper end being arranged on sample (3) is used for producing magnetic field and putting on magnetic field generation and the monitoring modular (2) of the magnetic induction simultaneously monitoring magnetic field on sample (3), is used for realizing the fixing of ultrasonic action module (1) and precision translation and the fixing device (4) fixing and rotating regulation of sample (3).
A kind of combined magnetic field the most according to claim 1 and ultrasonic generation vector property noinvasive focus on the device of electricity irritation, it is characterised in that described ultrasonic action module (1) includes:
Ultrasound pulse transmission receptor (11), is used for producing ultrasonic excitation signal and receiving ultrasound echo signal；
Ultrasonic transducer (12), it is fixed in described fixing device (4), is connected with described ultrasound pulse transmission receptor (11), for the excitation signal of telecommunication is converted into ultrasonic signal, and ultrasound echo signal is converted into voltage signal, it is achieved the energy conversion of voltage signal and ultrasonic signal；
Acoustic couplant (13), is arranged between described ultrasonic transducer (12) and sample (3), for the ultrasonic signal that ultrasonic transducer (12) produces coupled to sample (3), reduces the decay of ultrasonic signal.
A kind of combined magnetic field the most according to claim 1 and ultrasonic generation vector property noinvasive focus on the device of electricity irritation, it is characterised in that described magnetic field occurs to include with monitoring modular (2):
Power supply (21), is used for exporting electric current；
Electric magnet (22), is arranged at sample (3) top, connects power supply (21) and is used for, according to different supply currents, producing the action of a magnetic field of different magnetic induction on sample (3)；
Tesla meter (23), is arranged on the side of electric magnet (22), for realizing the monitoring in magnetic field, shows the magnetic induction in magnetic field in real time.
A kind of combined magnetic field the most according to claim 1 and ultrasonic generation vector property noinvasive focus on the device of electricity irritation, it is characterised in that described fixing device (4) includes: base (41), and:
Accurate translation stage (42), is arranged on described base (41), is used for fixing ultrasonic transducer (12), it is achieved the accurate translation of ultrasonic transducer (12)；
Turntable (43), it is possible to being arranged on described base (41) of 360 degree of rotations；
Carrying disk (44), is fixed on above described turntable (43), for placing sample (3) to be stimulated, and realizes 360 degree of rotations of sample (3) under the effect of turntable (43).
A kind of combined magnetic field the most according to claim 1 and ultrasonic generation vector property noinvasive focus on the device of electricity irritation, it is characterized in that, described magnetic field occurs vertical with the ultrasonic excitation signal direction of propagation that described ultrasonic action module (1) produces with the magnetic induction line direction, magnetic field that monitoring modular (2) produces, and magnetic induction line direction, described magnetic field is electricity irritation direction with the vector product direction of the ultrasonic excitation signal of generation.
A kind of combined magnetic field the most according to claim 1 and ultrasonic generation vector property noinvasive focus on the device of electricity irritation, it is characterised in that described sample (3) is the nonisulated property sample having certain electric conductivity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520983038.5U CN205411950U (en) | 2015-12-01 | 2015-12-01 | Combine magnetic field and supersound production vector nature not to have device of creating focus electro photoluminescence |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520983038.5U CN205411950U (en) | 2015-12-01 | 2015-12-01 | Combine magnetic field and supersound production vector nature not to have device of creating focus electro photoluminescence |
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| Publication Number | Publication Date |
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| CN205411950U true CN205411950U (en) | 2016-08-03 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201520983038.5U Expired - Fee Related CN205411950U (en) | 2015-12-01 | 2015-12-01 | Combine magnetic field and supersound production vector nature not to have device of creating focus electro photoluminescence |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105344023A (en) * | 2015-12-01 | 2016-02-24 | 中国医学科学院生物医学工程研究所 | Device for generating vector noninvasive focusing electrical stimulation in combination with magnetic field and ultrasonic |
| CN115359705A (en) * | 2022-08-18 | 2022-11-18 | 上海体育学院 | Demonstration system for nerve electrical stimulation |
-
2015
- 2015-12-01 CN CN201520983038.5U patent/CN205411950U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105344023A (en) * | 2015-12-01 | 2016-02-24 | 中国医学科学院生物医学工程研究所 | Device for generating vector noninvasive focusing electrical stimulation in combination with magnetic field and ultrasonic |
| CN115359705A (en) * | 2022-08-18 | 2022-11-18 | 上海体育学院 | Demonstration system for nerve electrical stimulation |
| CN115359705B (en) * | 2022-08-18 | 2023-09-19 | 上海体育学院 | Presentation system of nerve electrical stimulation |
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| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220214 Address after: 518107 18th floor, block B, high tech innovation center, guangqiao Road, Tianliao community, Yutang street, Guangming District, Shenzhen City, Guangdong Province Patentee after: SHENZHEN DELICA MEDICAL EQUIPMENT Co.,Ltd. Address before: 300192, 236 Bai Causeway Road, Tianjin, Nankai District Patentee before: CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUTE OF BIOMEDICAL ENGINEERING |
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| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160803 |
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| CF01 | Termination of patent right due to non-payment of annual fee |