CN201402230Y - Sample enriching and concentrating analyzing device - Google Patents

Sample enriching and concentrating analyzing device Download PDF

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Publication number
CN201402230Y
CN201402230Y CN2009200791943U CN200920079194U CN201402230Y CN 201402230 Y CN201402230 Y CN 201402230Y CN 2009200791943 U CN2009200791943 U CN 2009200791943U CN 200920079194 U CN200920079194 U CN 200920079194U CN 201402230 Y CN201402230 Y CN 201402230Y
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CN
China
Prior art keywords
sample
concentrates
example enrichment
analytical equipment
collection device
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN2009200791943U
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Chinese (zh)
Inventor
王保宁
杨卫平
周跃国
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sichuan Maker Biological Science and Technology Co., Ltd.
Original Assignee
SICHUAN MJAKER TECHNOLOGY Co Ltd
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Priority to CN2009200791943U priority Critical patent/CN201402230Y/en
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Publication of CN201402230Y publication Critical patent/CN201402230Y/en
Anticipated expiration legal-status Critical
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Abstract

The utility model discloses a sample enriching and concentrating analyzing device, which comprises a sample collector and a waste liquid collector which are detachably connected, wherein the sample collector is provided with a sample inlet formed above the waste liquid collector; a sample outlet is formed at and a primary filtering layer for sealing the sample outlet the bottom part of the samplecollector; a water absorption layer is arranged in the waste liquid collector; and a sample enriching and concentrating film is arranged on the upper surface of the water absorption layer, and is positioned below the sample outlet at the bottom of the sample collector. The sample enriching and concentrating analyzing device provided by the utility model adopts the scheme that an objected detectionobject in the body fluid is enriched and concentrated on the surface of the sample enriching and concentrating film to be convenient for the detection object to pass through detection reagent or a detection analyzer to perform next analysis and detection.

Description

Example enrichment concentrates analytical equipment
Technical field
The utility model relates to a kind of example enrichment and concentrates analytical equipment.
Background technology
At present, the analysis to human body fluid (comprising saliva, urine, blood, cerebrospinal fluid etc.) is one of important means of human body health condition or human body diseases.In fact, promptly be effective target contained in the body fluid to be detected thing (comprising albumen, DNA/RNA, cell, compound etc.) reach the whether ill situation of human body health condition or human body for the analysis of human body fluid.But, effective target in the body fluid detects thing, and often content is very low, because the problem of detecting instrument or the sensitivity of detectable card, if directly body fluid is detected often to detect less than effective target and detects thing, or the content error of detected effective target detection thing is very big, causes judged result inaccurate.
The utility model content
Technical problem to be solved in the utility model provide a kind of simple in structure, be convenient to that effective target contained in the body fluid is detected thing and carry out the example enrichment that effective enrichment concentrates or detect simultaneously and concentrate analytical equipment.
The technical scheme that the above-mentioned technical matters that solves the utility model adopts is: example enrichment concentrates analytical equipment, comprise the sample divider and the waste collection device that removably connect, sample divider has injection port and is positioned at waste collection device top, be provided with water accepting layer in the described waste collection device, the water accepting layer upper surface is provided with example enrichment and concentrates film, and described example enrichment concentrates the sample export below that film is positioned at the sample divider bottom.
Have sealed sample outlet in the described sample divider or be positioned at the prefiltration layer of sample export top.
Described prefiltration layer is filter paper or the above filter screen of 100 orders.
Described example enrichment concentrates film and is filter paper, nylon membrane, cellulose membrane, glass fibre membrane or contains the earth silicon material film.Or other have the material of pathoklisis to albumen, cell nucleic acid, can adsorb at detecting target.
Described water accepting layer is filter paper, super absorbent resin or super absorbent polymer polymkeric substance.As poly starch etc.
Described sample divider and waste collection device are for being threaded or clamping.Or other are convenient to connected mode that sample divider, waste collection device are separated.
The sample export place of described sample divider bottom is provided with this sample export of control and switches to gauge tap under connection, blocking state.Gauge tap can be devices such as ball valve two logical switches, so that the control example enrichment concentrates the duty of analytical equipment.
Described waste collection device is provided with at least one air hole.This structure can be avoided occurring causing the situation that waste collection device internal gas pressure increases after waste liquid flows into the waste collection device.
The volume of described waste collection device is more than or equal to the volume of sample divider.This setting is a situation of avoiding occurring occurring in the waste collection device waste liquid spill-over.
The example enrichment of this programme concentrates analytical equipment and at first sample solution is joined sample divider through injection port, directly or through the prefiltration layer carry out flowing out from sample export behind the prefiltration, flow through and pass the concentrated film of example enrichment, because concentrating the film below, example enrichment has hydrophilic water accepting layer, the small-molecule substance that comprises water passes example enrichment and concentrates film and adsorbed by water accepting layer, the target detection thing then is trapped example enrichment and concentrates the film surface, target detection thing after enrichment concentrates is convenient to carry out next step analyzing and testing by detectable card or check and analysis instrument, because example enrichment concentrates the sample divider and the waste collection device of analytical equipment and removably connects, therefore concentrate film in the enrichment of needs sample thief and carry out taking apart when next step is analyzed sample divider, take off the concentrated film of example enrichment or directly concentrate on the film with tweezers or other instruments and detect in enrichment; The enrichment that the concentrated analytical equipment of this enrichment can be used for albumen, nucleic acid, cell or other components of body fluid (comprising saliva, urine, blood, cerebrospinal fluid etc.) concentrates, extracts and directly analyzes or indirect analysis.
In sum, the beneficial effects of the utility model are: example enrichment of the present utility model concentrates analytical equipment the target detection thing enrichment in the body fluid is concentrated to the concentrated film surface of example enrichment, so that the target detection thing carries out next step analyzing and testing by detectable card or check and analysis instrument.
Below in conjunction with drawings and Examples example enrichment of the present utility model is concentrated analytical equipment and be further described, but the utility model is not limited to embodiment.
Description of drawings
Fig. 1 is the decomposition texture synoptic diagram of each assembly of the utility model;
Fig. 2 is the cut-open view after the utility model embodiment 1 assembling;
Fig. 3 is the cut-open view after the utility model embodiment 2 assemblings;
Fig. 4 is the cut-open view after the utility model embodiment 3 assemblings;
Fig. 5 is the cut-open view after the utility model embodiment 4 assemblings.
Embodiment
Embodiment 1:
With reference to Fig. 1, shown in Figure 2, example enrichment of the present utility model concentrates analytical equipment and comprises sample divider 2 and the waste collection device 7 that removably connects, and removably connecting herein can be to be threaded or clamping, and present embodiment adopts and is threaded; The volume of waste collection device 7 is greater than the volume of sample divider 2, and waste collection device 7 is provided with at least one air hole 6, air hole is arranged at the higher position of waste collection device sidewall, sample divider 2 has injection port and is positioned at waste collection device 7 tops, described sample divider 2 bottoms have sample export and seal the prefiltration layer 1 of this sample export, prefiltration layer 1 is the gland bonnet sample export directly, perhaps sample export place or sample export top is provided with a baffle plate with at least one through hole, and prefiltration layer 1 is sealed on this baffle plate; The sample export place of described sample divider 2 bottoms is provided with this sample export of control and switches to gauge tap 3 under connection, blocking state; Be provided with water accepting layer 5 in the described waste collection device 7, water accepting layer 5 upper surfaces are provided with example enrichment and concentrate film 4, described example enrichment concentrates the sample export below that film 4 is positioned at sample divider 2 bottoms, in the present embodiment, water accepting layer 5 has covered the cavity of whole waste collection device 7, and sample divider 2 bottoms are taper.
In the present embodiment, the diameter that example enrichment concentrates film should be not less than 0.1mm, and the volume of sample divider should be not less than 0.5ml, and its concrete specification kind or detection demand is per sample done adaptive change.
Embodiment 2:
Referring to shown in Figure 3, the difference of present embodiment and embodiment 1 is, sample divider 2 bottoms of present embodiment are plane, simultaneously, the sample export of present embodiment can be set to one or more, and the waste collection device 7 of present embodiment is separated into upper and lower two parts by a baffle plate with at least one through hole is set with the cavity of waste collection device 7 within it, and water accepting layer 5 has covered the top of the cavity of waste collection device 7, and other each several part structures of present embodiment are identical with embodiment 1.
Embodiment 3:
Referring to shown in Figure 4, the difference of present embodiment and embodiment 1 is, the waste collection device 7 of present embodiment is provided with several by wall within it and is positioned at concavo-convex supporting construction or the concavo-convex supporting construction 8 of ring-shaped continuous on the same level height, water accepting layer 5 is positioned on this interior male structure, in the lower part of water accepting layer 5, also has certain cavity.
Embodiment 4:
Referring to shown in Figure 5, the difference of present embodiment and embodiment 1 is, sample divider 2 bottoms of present embodiment be dome shape, other each several part structures of present embodiment are identical with embodiment 1.

Claims (9)

1, example enrichment concentrates analytical equipment, it is characterized in that, comprise the sample divider (2) and the waste collection device (7) that removably connect, sample divider (2) has injection port and is positioned at waste collection device (7) top, be provided with water accepting layer (5) in the described waste collection device (7), water accepting layer (5) upper surface is provided with example enrichment and concentrates film (4), and described example enrichment concentrates the sample export below that film (4) is positioned at sample divider (2) bottom.
2, example enrichment according to claim 1 concentrates analytical equipment, it is characterized in that, has the prefiltration layer (1) that sealed sample exported or be positioned at the sample export top in the described sample divider (2).
3, example enrichment according to claim 1 and 2 concentrates analytical equipment, it is characterized in that, described prefiltration layer (1) is filter paper or the above filter screen of 100 orders.
4, example enrichment according to claim 1 and 2 concentrates analytical equipment, it is characterized in that, described example enrichment concentrates film (4) to be filter paper, nylon membrane, cellulose membrane, glass fibre membrane or to contain the earth silicon material film.
5, example enrichment according to claim 1 and 2 concentrates analytical equipment, it is characterized in that described water accepting layer (5) is filter paper, super absorbent resin or super absorbent polymer polymkeric substance.
6, example enrichment according to claim 1 and 2 concentrates analytical equipment, it is characterized in that described sample divider (2) and waste collection device (7) are for being threaded or clamping.
7, example enrichment according to claim 1 and 2 concentrates analytical equipment, it is characterized in that, the sample export place of described sample divider (2) bottom is provided with this sample export of control and switches to gauge tap (3) under connection, blocking state.
8, example enrichment according to claim 1 and 2 concentrates analytical equipment, it is characterized in that described waste collection device (7) is provided with at least one air hole (6).
9, example enrichment according to claim 1 and 2 concentrates analytical equipment, it is characterized in that the volume of described waste collection device (7) is more than or equal to the volume of sample divider (2).
CN2009200791943U 2009-02-23 2009-02-23 Sample enriching and concentrating analyzing device Expired - Lifetime CN201402230Y (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2009200791943U CN201402230Y (en) 2009-02-23 2009-02-23 Sample enriching and concentrating analyzing device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009200791943U CN201402230Y (en) 2009-02-23 2009-02-23 Sample enriching and concentrating analyzing device

Publications (1)

Publication Number Publication Date
CN201402230Y true CN201402230Y (en) 2010-02-10

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105223061A (en) * 2015-11-06 2016-01-06 长春市博坤生物科技有限公司 A kind of biological liquid sample gathers enrichment method and device
CN105319088A (en) * 2014-06-25 2016-02-10 四川大学 Pre-treatment method of detection of liquid sample with laser-induced breakdown spectroscopy
CN107099437A (en) * 2017-03-10 2017-08-29 泰山医学院 It is a kind of that the method that yellow water produces liquor seasoning product is concentrated with super-strong moisture absorbing resin

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105319088A (en) * 2014-06-25 2016-02-10 四川大学 Pre-treatment method of detection of liquid sample with laser-induced breakdown spectroscopy
CN105319088B (en) * 2014-06-25 2018-07-06 四川大学 A kind of pre-treating method of laser induced breakdown spectroscopy detection fluid sample
CN105223061A (en) * 2015-11-06 2016-01-06 长春市博坤生物科技有限公司 A kind of biological liquid sample gathers enrichment method and device
CN107099437A (en) * 2017-03-10 2017-08-29 泰山医学院 It is a kind of that the method that yellow water produces liquor seasoning product is concentrated with super-strong moisture absorbing resin

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Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
C56 Change in the name or address of the patentee

Owner name: SICHUAN MAKER SCIENCE AND TECHNOLOGY CO.,LTD.

Free format text: FORMER NAME: SICHUAN PROVINCE MAKER TECHNOLOGY CO., LTD

CP03 Change of name, title or address

Address after: No. 16, Lu, 611731, hi tech Zone, Sichuan, Chengdu

Patentee after: Sichuan Maker Biological Science and Technology Co., Ltd.

Address before: No. 16, Lu, 611731, hi tech Zone, Sichuan, Chengdu

Patentee before: Sichuan Mjaker Technology Co., Ltd.

EE01 Entry into force of recordation of patent licensing contract

Assignee: SICHUAN MAKER BIOMEDICAL ELECTRONIC CO., LTD.

Assignor: Sichuan Maker Biological Science and Technology Co., Ltd.

Contract record no.: 2014510000174

Denomination of utility model: Sample enriching and concentrating analyzing device

Granted publication date: 20100210

License type: Common License

Record date: 20141112

LICC Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model
CX01 Expiry of patent term

Granted publication date: 20100210

CX01 Expiry of patent term