CN201273873Y

CN201273873Y - Liquid base shallow layer cell tabletting apparatus

Info

Publication number: CN201273873Y
Application number: CNU2008202106528U
Authority: CN
Inventors: 肖国林
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-03-27
Filing date: 2008-09-25
Publication date: 2009-07-15
Anticipated expiration: 2018-09-25

Abstract

The utility model relates to a device for making liquid substrate thin layer cell sheets, which is used in biological cytology. The utility model is characterized in that a hanging disc is fixed on a centrifuge rotor; the hanging disc is provided with a plurality of hanging holes; and latch hooks are arranged on a cell storing bottle and a smear clamp. Because the device is provided with the smear clamp and the cell storing bottle with the latch hooks (or the latch hooks are arranged on the smear clamp and the cell storing bottle), the device has the advantages of convenient operation, simple use, firm installation and safe and stable operation, cells are collected and separated and the cell sheets are made on one centrifuge, and the made cell sheets have the advantages of uniform cells, single-layer flat cells and clean background. In the production process, because the structure is simple, a standard device is often used or the standard device can be used through being simply reformed, the production is easy, and the cost is low.

Description

A kind of liquid based thin-layer cell pelletizer

Technical field

The utility model relates to a kind of device that is applied to manufacture in the biocytology liquid based thin-layer cell sheet.

Background technology

Liquid based thin-layer cell flaking method utilizes liquid base technology exactly, and useful cell transfer to microslide, is formed that cell is neat evenly, individual layer tiling, the clean cell sheet of background, so that researchist's observational study clearly.The liquid based thin-layer cell production facility of present most economical practicality all adopts the mode of centrifugal force transitional cell.This equipment generally includes special-purpose centrifugal rotor and special-purpose smear folder, and the cell that also contains that has is preserved devices such as bottle.This equipment exists in actual use that easy-offtaking smear folder and slide, smear folder are not installed deficiencies such as insecure or complicated operating process; Exist problems such as complex process and input height in process of production.

Summary of the invention

Exist slide and smear to press from both sides easy-offtaking not, the deficiency that insecure, film-making process complexity etc. is used is installed in order to overcome existing liquid based thin-layer cell production facility, with the difficulty that solves in complex process, the high manufacturing of production cost, the utility model provides a kind of liquid based thin-layer cell pelletizer, this device is not only simple to operation, safe in utilization, and manufacturing process is simple, with low cost.

The technical scheme that its technical matters that solves the utility model adopts is; A kind of liquid based thin-layer cell pelletizer is made up of centrifugal rotor, cell preservation bottle, smear folder, it is characterized in that being fixed with on the centrifugal rotor extension dish, and several hanging holes are arranged on the extension dish, and cell preservation bottle and smear press from both sides hook is installed.The smear folder and the cell that have hook are preserved bottle (or loading onto hook on smear folder and preservation bottle), are stained with filtering membrane on the smear folder, and the slide groove that can conveniently plug and can firmly install filter paper and microslide is arranged, and cell is preserved a bottle bottom and had tapering.During collecting cell, the hook of preserving on the bottle is hung on the extension dish, after starting hydro-extractor, cell is preserved bottle and is hung more firmly under centrifugal action, and be turned near horizontality along the axle center of extension dish, cell also moves to bottle position of base cone degree part under centrifugal action, reached the purpose of cell and other separating substances, is convenient to collecting cell; During film-making, on the hook extension dish on the smear folder, same smear is clipped under the action of centrifugal force and is turned near horizontality, useful cell-penetrating filtering membrane is transferred on the microslide, impurity is filtered film and blocks, and remaining liquid is absorbed by filter paper, and the smear area equates with the smear open area, the formation cell is neat evenly, individual layer tiles, the clean cell sheet of background, reaches the purpose of quick Fabrication liquid based thin-layer cell sheet.

The beneficial effects of the utility model are: in use, preserve the mode that has adopted hook and extension dish that cooperates of bottle and smear folder owing to centrifugal rotor and cell, so it is easy to operate, use simple, install firmly, move safety and stability more, being produced on the desk centrifuge of the collection separation of cell and cell sheet finished, and be economical and practical; Owing to adopted filtering membrane, filter paper and had the frame modes such as bottle of tapering, the cell sheet cell of making is neat evenly, individual layer tiles, background is clean.In process of production, because simple in structure, majority adopts standard components or it is just transformed simply and can use, and produces simple, with low cost.

Description of drawings

Fig. 1 is that the extension dish hangs up the structural drawing that cell is preserved bottle.

Fig. 2 is the structural drawing that the extension dish hangs up the smear folder.

Fig. 3 is the schematic top plan view of extension dish.

Embodiment

In Fig. 1, the hook 7 that cell is preserved bottle 6 hangs on the hanging hole 8 of extension dish 1, and cell is preserved the size of hook 7 on the bottle 6 and matched with hanging hole 8 on the extension dish, guarantees that cell preserves bottle 6 and can revolve on axial and turn 90 degrees, and can make things convenient for getting, stablely during centrifugal rotation do not break away from.When being installed in centrifugal rotor 9 on the hydro-extractor, during centrifugal rotor 9 rotating operations, under action of centrifugal force, cell is preserved bottle 6 can be along the upwards upset of axis of extension dish 1, object in the bottle can be apace direction motion at the bottom of bottle, the tapering part at the bottom of heavier relatively cell and impurity finally are attached to bottle tightly is behind the centrifugal intact liquid of outwelling in the bottle, only remaining cell and bigger impurity in the bottle have been finished the separation of cell and have been collected step.

In Fig. 2, the hook 7 of smear folder 2 hangs on the hanging hole 8 of extension dish 1, and filtering membrane 3 is attached to the outlet for lantern slide that is coated with of smear folder 2, and filter paper 4 is close in the outside, and outermost layer inserts microslide 5 again.For guaranteeing that microslide 5 can not come off when the centrifugal motion, the degree of depth that smear presss from both sides 2 slide grooves is little, is advisable to clamp slide 5; For guaranteeing to make things convenient for the length that extraction filter paper 4 and microslide 5, smear press from both sides 2 slide grooves to lack, generally be not more than 3/4ths of microslide 5 length.When being installed in centrifugal rotor 9 on the hydro-extractor, during centrifugal rotor 9 rotating operations, under action of centrifugal force, smear folder 2 can upwards be turned to horizontal direction along the axis of extension dish 1, liquid in the folder etc. are along the direction motion of centrifugal force, and bigger impurity etc. is filtered film 3 and blocks, and cell and liquid pass filtering membrane 3, cell all attaches on the microslide 5, and liquid is sponged by filter paper 4.Behind centrifugal the finishing, smear folder 2 can return to the vertical hanging state, takes out smear folder 2, and microslide 5 and filter paper 4 are extracted out simultaneously, separates microslide 5 and filter paper 4, and the cell sheet completes.

In Fig. 3, it is 1 in the form of annular discs that the extension on the centrifugal rotor 9 coils, and several hanging holes 8 are arranged on the extension dish 1.

Cell preserves that the hook 7 of hook 7, the smear folder 2 of bottle 6 can be preserved bottle 6 with cell, smear folder 2 be an integral production, can be fixed on also that cell is preserved bottle 6, smear presss from both sides on 2.

Claims

1, a kind of liquid based thin-layer cell pelletizer, form by centrifugal rotor (9), cell preservation bottle (6), smear folder (2), it is characterized in that being fixed with on the centrifugal rotor (9) extension dish (1), hanging hole (8) is arranged on the extension dish (1), cell is preserved on bottle (6) and the smear folder (2) and is being fixed hook (7), and cell is preserved bottle (6) and smear folder (2) and hung over hanging hole (8) and upward be connected with extension dish (1) by linking up with (7).

2, a kind of liquid based thin-layer cell pelletizer according to claim 1 is characterized in that several hanging holes (8) are arranged on the extension dish (1).