CN1965653A - Disinsection composition of acetamiprid and pymetrozine - Google Patents

Abstract

The invention relates to an insecticidal composition and its preparing process, wherein the composition comprises effective compositions of acetaniprid and pymetrozine with a preferred weight ratio of 1:10-1:30. The composition has appreciable synergic action in controlling cotton aphid.

Description

Acetamiprid and pyrrole aphid ketone Pesticidal combination

Technical field

The present invention relates to Acetamiprid (active ingredient I hereinafter referred to as) and pyrrole aphid ketone (active ingredient II hereinafter referred to as) is the binary Pesticidal combination of active ingredient, its preparation can be used for preventing and treating pest, wherein cotten aphid particularly.

Background technology

Acetamiprid (acetamiprid) as active ingredient I is a second generation anabasine insecticide, mainly acts on the neural joint portion of insect caudacoria, makes the insect exaltation by combine with acetylcholinergic receptor, whole body spasm, paralysis and extremely.Not only interior absorption is strong, wide, the active height of insecticidal spectrum and speed of action is fast, the lasting period is long.The insect that pyrethroid, organic phosphates, carbamates is produced resistance is also effective.Can be used for preventing and treating homoptera pest such as aphid, plant hopper, aleyrodid, a red-spotted lizard, leafhopper etc., lepidoptera pest such as diamond-back moth, Liriomyza, Grapholita spp etc., coleopteran pest longicorn etc., thrips order insect thrips etc.To most of crops particularly vegetables such as wild cabbage, Chinese cabbage, radish, cucumber, watermelon, eggplant, capsicum etc., fruit tree such as apple, oranges and tangerines, pears, peach, grape, strawberry etc., tea, potato, tobaccos etc. are to crop safety, no poisoning, little to the influence of wildlifes such as honeybee under recommended dose.

Pyrrole aphid ketone (pymetrozine) as active ingredient II belongs to Triazinone, and mechanism of action uniqueness is all inequality with the known insecticide mechanism of action, does not have cross resistance with existing insecticide.Under the recommended dose to crop, Environmental security, no poisoning.

Two kinds of mixing active ingredients proportionings are I: II=1: 10 to 1: 50, be preferably 1: 10 to 1: 30, and for example preferred proportioning is 1: 10,1: 30 a composition.

This two single agent is mixed, and synergy is remarkable.New through looking into, do not see this mixture report both at home and abroad as yet.

Summary of the invention

The purpose of this invention is to provide a kind of is the Pesticidal mixture made of active ingredient with Acetamiprid and pyrrole aphid ketone.

Another object of the present invention provides the preparation method of described this mixture.

This Pesticidal combination comprises that effective composition quality mark is an Acetamiprid 1%～5%, pyrrole aphid ketone 10%～50%, preferred Acetamiprid 1%～2%, pyrrole aphid ketone 10%～30%.

The mixture that active ingredient I and II form generally uses with preparation.Said composition can be processed into formulations such as aqua, suspending agent, wetting powder.The method for optimizing of using said composition is a foliage-spray, and formulation rate is 30～90g a.i./ha usually.

Preparation prepares in a known manner, normally active ingredient is fully mixed with surfactant, solvent or solid carrier or grinds.The acidulant acidifying normally used active ingredient by aqua, adds auxiliary agent and water again, stirs.

Pesticidal combination generally includes 11%～51% active ingredient I and II, 6%～15% surfactant, 34%～83% solid packing or liquid adjuvants.

The target crop that is fit to is cereal crops such as wheat, corn, Chinese sorghum particularly, economic crops such as cotton, crudefiber crop, soybean, peanut, vegetable crops such as tomato, eggplant, capsicum, lettuce, celery, wild cabbage, Kidney bean, broad bean, cowpea, pea, ground family crops such as cucumber, pumpkin, watermelon, solanaceous crops such as tobacco, potato, fruit tree crops such as apple, oranges and tangerines, pears, peach, grape, strawberry, flower plants such as chrysanthemum, China pink.

The insect that is fit to also has aphid on wheat aphid, vegetable aphid, melon aphid, citrus aphid, wooly aphis, other fruit trees, soybean aphid or the like except that cotten aphid.

The surfactant that is fit to is an alkylbenzenesulfonate, lignosulfonates, alkylnaphthalene sulfonate, petroleum sodium sulfonate, aliphatic alcohol sulfate, fatty alcohol polyoxyethylene ether sulfate, alkylphenol polyoxyethylene formaldehyde condensation products sulphate, alkylphenol polyoxyethylene, naphthalene sulfonic acid-formaldehyde condensation product, alkylphenol polyoxyethylene formaldehyde condensation products, polyoxyethylene carboxylate, vegetable oil ethylene oxide adduct and derivative etc., preferably OP series, neopelex, draw back powder, NNO, spent pulping liquor etc. have good emulsifying, the nonionic and the anion surfactant of dispersion and wettability.

The solid carrier that is suitable for wetting powder is bentonite, attapulgite, kaolin, imvite, diatomite, potter's clay, white carbon, talcum powder, clay etc.

The acidulant that is fit to has organic acid and inorganic acids such as hydrochloric acid, sulfuric acid, sulfonic acid, lactic acid, citric acid, acetate, formic acid.

Embodiment

The present invention describes with the following example, but does not limit the present invention.

Example of formulations 1:11% aqua

Acetamiprid 1%

Pyrrole aphid ketone 10%

Hydrochloric acid 20%

OP-10 8％

Running water to 100%

Active ingredient acidulant acidifying adds surfactant and running water, fully is hybridly prepared into aqua, can be diluted to the aqueous solution of any desired concn to water.

Example of formulations 2:22% suspending agent

Acetamiprid 2%

Pyrrole aphid ketone 20%

Polyvinyl alcohol 10%

NNO 2％

OP-10 5％

Water to 100%

Active ingredient is fully mixed with adjuvant, in agitator, fully grind, be made into suspending agent with 3～5mm bead.Can be diluted to the suspension of any desired concn to water.

Example of formulations 3:31% wetting powder

Acetamiprid 1%

Pyrrole aphid ketone 30%

Neopelex 5%

Spent pulping liquor 5%

Talcum powder to 100%

Acetamiprid and pyrrole aphid ketone and auxiliary agent, filler are pulverized through airslide disintegrating mill, and abundant mixing can be made into wetting powder in mixing kettle again.Can be diluted to the suspension of any desired concn to water.

Biologicall test embodiment 1

The blade infusion process that the Toxicity Determination method adopts FAO (1980) to recommend.Earlier reagent agent is carried out preliminary survey, be diluted to 5 gradient concentrations by the multiple proportions relation on its basis, the cotton seedling of band aphid is taken out flood 5s in soup after, inhale with filter paper immediately and remove unnecessary soup, with writing brush rejecting alatae with if aphid, keep aptery one-tenth aphid of the same size, the aphid number on the number scutching cotton leaf is put into then in the greenhouse and normally cultivates.3 repetitions of each concentration are contrast with the dimethyl sulphoxide aqueous solution.Check dead aphid number behind the 24h, stir polypide with writing brush during inspection, the examination worm is motionless fully to be dead, and the contrast lethality is invalid test greater than 10%, and the gained lethality is obtained corrected mortality with the Abbott formula.Logarithm value with drug concentration is independent variable x then, is dependent variable Y with the probit value of corrected mortality, obtains virulence regression equation (Y=A+Bx), lethal concentration of 50 LC with method of least squares ₅₀And LC ₉₀, and correlation coefficient (R).

The synergism test method is undertaken by the co-toxicity coefficient method of Sun Yunpei.Press the co-toxicity coefficient that routine formula calculates Mixed Pharmacy:

The ratio of ratio+B toxicity index * B of the theoretical toxicity index of mixture=A toxicity index * A

The CTC of mixture is synergistic effect greater than 100, is remarkable synergy greater than 120; It about 100 summation action; Less than 100 is antagonism.

LC according to Acetamiprid and pyrrole aphid ketone ₅₀, the Acetamiprid of determining and the proportioning of pyrrole aphid ketone are 5 proportionings such as 1: 30,1: 20,1: 10,1: 5,1: 2.5.The indoor virulence measurement result that is mixed sees Table 1.

Table 1 Acetamiprid and the pyrrole aphid ketone indoor virulence measurement result that is mixed

Medicament	Virulence regression equation	LC 50 (mg/L)	LC 90 (mg/L)	R	95% confidence limit	CTC
							Acetamiprid pymetrozine pyridine: pyrrole=pyridine in 1: 30: pyrrole=pyridine in 1: 20: pyrrole=pyridine in 1: 10: pyrrole=pyridine in 1: 5: pyrrole=1: 2.5	Y＝5.895+1.297x Y＝4.150+1.286x Y＝5.415+1.091x Y＝4.293+2.005x Y＝5.479+1.456x Y＝4.836+1.945x Y＝5.316+2.511x	0.204 4.580 0.417 2.254 0.469 1.214 0.748	1.984 45.481 6.229 9.822 3.562 5.539 2.424	0.9526 0.9507 0.9817 0.9897 0.9946 0.9891 0.9895	(0.163～0.255) (3.276～6.404) (0.317～0.548) (1.931～2.631) (0.380～0.579) (1.034～1.427) (0.667～0.839)	649.1 100.5 331.0 82.5 85.9

As seen from Table 1, Acetamiprid and pyrrole aphid ketone proportioning are 1: 10 and 1: 30 o'clock, and the co-toxicity coefficient of mixture is up to more than 300, and its synergistic effect is quite remarkable, and other several proportionings are essentially summation action.So the proportioning Acetamiprid of selecting: pyrrole aphid ketone is 1: 10 or 1: 30.

Biologicall test embodiment 2

Field control effectiveness test is established 6 processing altogether: reagent agent is 11% pyridine pyrrole aqua (AS) 20,30,40g/ mu, contrast medicament 25% pyrrole aphid ketone WP 20g/ mu, 3% Acetamiprid EC 20g/ mu, and blank.Repeat 4 times, totally 24 processing.In cotten aphid occurrence in peak period cotton strain even spraying.

Every processing sub-district is got 5 points at random, demarcates the cotton seedling of 10 strains at every, investigation insect population radix before the dispenser, and 1d, 3d, 7d respectively investigate 1 time after the dispenser, put down in writing residual borer population alive respectively, calculate go down rate and proofread and correct preventive effect of insect population, and result of the test is carried out variance analysis.Investigation simultaneously has or not symptom of chemical damage for studying thing.Determine the safety of medicament.

From result of the test (seeing Table 2) as can be seen, that first day preventive effect is best behind the medicine is 11% pyridine pyrrole AS (40g/ mu), preventive effect is 93.20%, next is 3% Acetamiprid EC, preventive effect is 91.53%, that preventive effect is relatively poor is 25% pyrrole aphid ketone WP, only is 33.10%, and 3 processing of reagent agent are apparently higher than contrast medicament 25% pyrrole aphid ketone WP.As seen from Table 3, the preventive effect difference of 3d, 7d is not remarkable behind the medicine, and preventive effect is 97.86%～99.79%.The drug effect that shows pyrrole aphid ketone is slower, is mixed with Acetamiprid, can significantly improve its quick-acting.

Duration of test is observed, and cotton does not have any symptom of chemical damage, and test medicine is to cotton safety.

Table 2 11% Acetamiprid pyrrole aphid ketone As field test results (1d behind the medicine) Shandong 2005.8

Handle	Dosage (g/ mu)	Insect population radix before the dispenser	Borer population (head) alive	The insect population rate (%) that goes down	Proofread and correct preventive effect (%)	Significance 0.05 0.01
							11% pyridine pyrrole AS	20 30 40	871.8 662.0 685.8	161.0 94.25 39.75	81.70 86.13 93.62	80.49 85.21 93.20	B A ab A a A
25% pyrrole aphid ketone WP, 3% Acetamiprid EC	20 20	743.0 793.0	481.5 62.25	37.26 92.06	33.10 91.53	c B ab A
							CK	0	585.3	544.0	6.210	0	- -

Annotate: data are 4 repetition mean values in the table.

Table 3 11% Acetamiprid pyrrole aphid ketone AS field test results (3d and 7d behind the medicine) Shandong 2005.8

Handle	3d behind the medicine				7d behind the medicine
									Borer population (head) alive	The insect population rate (%) that goes down	Proofread and correct preventive effect (%)	Significance 0.05 0.01	Borer population (head) alive	The insect population rate (%) that goes down	Proofread and correct preventive effect (%)	Significance 0.05 0.01
	11% pyridine pyrrole AS	13.25 10.25 7.25	98.50 98.58 98.81	99.28 99.32 99.43	a A a A a A	14.25 3.750 1.750	98.24 99.40 99.69	98.76 99.58 99.79									a A a A a A
25% pyrrole aphid ketone WP, 3% Acetamiprid EC									13.75 32.00	97.97 95.55	99.03 97.86	a A a A	3.000 8.000	99.57 99.01	99.70 99.31	a A a A
	CK	1264	-108.0	0	- -	844.3	-42.27	0									- -

Annotate: data are 4 repetition mean values in the table.

Claims (5)

1. Pesticidal combination, active ingredient wherein is Acetamiprid (active ingredient I) and pyrrole aphid ketone (active ingredient II), the weight ratio of I: II is 1: 10 to 1: 50.

2. according to the Pesticidal combination of claim 1, wherein the weight ratio of I: II is 1: 10 to 1: 30.

3. the method for a pest control wherein will spray with 30～90g a.i./ha according to the Pesticidal combination of claim 1 and prevent and treat pest on crop.

4. according to the method for claim 3, wherein preventing and treating crop is cotton-plant pest-insects.

5. according to the method for claim 3, wherein controlling object is a cotten aphid.