CN1951491A - Method for preparing blood replenishing capsule 'Wei Xue Kang' - Google Patents

Method for preparing blood replenishing capsule 'Wei Xue Kang' Download PDF

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Publication number
CN1951491A
CN1951491A CN 200610032119 CN200610032119A CN1951491A CN 1951491 A CN1951491 A CN 1951491A CN 200610032119 CN200610032119 CN 200610032119 CN 200610032119 A CN200610032119 A CN 200610032119A CN 1951491 A CN1951491 A CN 1951491A
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add
hours
kang
water
capsule
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CN 200610032119
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肖云生
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HUNAN KEWEI PHARMACEUTICAL CO Ltd
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HUNAN KEWEI PHARMACEUTICAL CO Ltd
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Abstract

The invention relates to a process for preparing Weixuekang capsules from medicinal materials based on prescriptions of Weixuekang syrup. The capsules have the functions of tonifying kidney, enlivening spleen, enriching blood and nourishing yin energy, and can be used for treating blood deficiency, sallow complexion, megrims, tinnitus, soreness and weakness of the lumbar region, trophism hyphemia and iron-deficiency anemia.

Description

The method for making of blood replenishing capsule ' Wei Xue Kang '
Technical field
The invention belongs to the medical science technical field of Chinese patent medicine, relate to a kind of method for making of blood replenishing capsule ' Wei Xue Kang ' specifically.
Background technology
The prescription of blood replenishing capsule ' Wei Xue Kang ' of the present invention derives from " the infantile health-care capsule syrup " that Chinese Pharmacopoeia one one of version in 2005 is recorded, 20ml of infantile health-care capsule syrup adult, and 10ml of children's, adult one is to take 60ml, and children's took 30ml on 1st, and dose is big.And this syrup sugar content height is unfavorable for that some avoids sugared disease patient and take; Former syrup dosage is liquid preparation, is unfavorable for transporting, carry, preserve and taking.
Summary of the invention
Purpose of the present invention belongs to above-mentioned patient with a kind of suitable nutritional anemia, the iron deficiency anemia that the specific method for making of prescription medical material employing of " infantile health-care capsule syrup " is made exactly, is convenient to the blood replenishing capsule ' Wei Xue Kang ' that transports, carries, preserves and take.
Main technical schemes of the present invention is as follows:
A kind of method for making of blood replenishing capsule ' Wei Xue Kang ', prescription derives from " infantile health-care capsule syrup ", is characterized in: blood replenishing capsule ' Wei Xue Kang ' in process of production, except that sulphuric acid was ferrous, the Pericarpium Citri Reticulatae of Fructus Amomi and half amount extracts Aromatic water with steam distillation, and was standby; Medicinal residues and remaining Pericarpium Citri Reticulatae and remaining confederates' ginseng thereof, Radix Rehmanniae Preparata, Semen sojae atricolor, Rhizoma Dioscoreae, Radix Polygoni Multiflori, the Fructus Crataegi Six-element decocts with water secondary, each 2 hours, filters, merging filtrate, and be concentrated in right amount, add ethanol and make and contain the alcohol amount and reach 60%, leave standstill, draw supernatant, reclaim ethanol, put and be chilled to room temperature, filter, filtrate decompression concentrates, and dry, pulverizing adds above-mentioned ferrous sulfate and starch mixing, granulate, spray into Aromatic water, mixing, encapsulated, promptly.
Blood replenishing capsule ' Wei Xue Kang ' in process of production, except that sulphuric acid was ferrous, the Pericarpium Citri Reticulatae of Fructus Amomi and half amount adds 8~14 times of water gagings and extracted Aromatic water in 5 hours with the steam distillation distillation, and was standby; Medicinal residues and remaining Pericarpium Citri Reticulatae and remaining confederates' ginseng thereof, Radix Rehmanniae Preparata, Semen sojae atricolor, Rhizoma Dioscoreae, Radix Polygoni Multiflori, Fructus Crataegi Six-element, decoct with water secondary, add 8~12 times of water gagings for the first time, add 6~10 times of water gagings for the second time, each 2 hours, filter merging filtrate, and be concentrated into the clear paste that relative density is 1.05~1.15 (60 ℃), and put to room temperature, add ethanol and make and contain alcohol amount and reach 60%, left standstill 24 hours, and drew supernatant, reclaim ethanol, put and be chilled to room temperature, filter, filtrate is at-0.05~0.095Mpa, and being evaporated to relative density under 50 ℃~100 ℃ the condition is the thick paste of 1.25~1.40 (60 ℃), then with thick paste at-0.06Mpa, dry under 70 ℃ the condition, pulverize, add above-mentioned ferrous sulfate and starch mixing, granulate, spray into Aromatic water, mixing, encapsulated, promptly.
Blood replenishing capsule ' Wei Xue Kang ' in process of production, except that sulphuric acid was ferrous, the Pericarpium Citri Reticulatae of Fructus Amomi and half amount adds 12 times of water gagings and extracted Aromatic water in 5 hours with the steam distillation distillation, and was standby; Medicinal residues and remaining Pericarpium Citri Reticulatae and remaining confederates' ginseng thereof, Radix Rehmanniae Preparata, Semen sojae atricolor, Rhizoma Dioscoreae, Radix Polygoni Multiflori, Fructus Crataegi Six-element, decoct with water secondary, add 10 times of water gagings for the first time, add 8 times of water gagings for the second time, each 2 hours, filter merging filtrate, and be concentrated into the clear paste that relative density is 1.10 (60 ℃), and put to room temperature, add ethanol and make and contain alcohol amount and reach 60%, left standstill 24 hours, and drew supernatant, reclaim ethanol, put and be chilled to room temperature, filter, filtrate is at-0.06Mpa, being evaporated to relative density under 70 ℃ the condition is the thick paste of 1.30 (60 ℃), then just thick paste at-0.06Mpa, dry under 70 ℃ the condition, pulverize, adding above-mentioned ferrous sulfate and starch mixing, is wetting agent with 70% ethanol, and 18 mesh sieves are granulated, 60 ℃ of dryings, 18 mesh sieve granulate add magnesium stearate again, spray into Aromatic water, mixing, airtight 2 hours, encapsulated, promptly.
Blood replenishing capsule ' Wei Xue Kang ' of the present invention is used for kidney and spleen invigorating, the function of the yin nourishing of enriching blood.Be applicable to the spleen kidney deficiency, essence and blood loses empty, shallow complexion, and vertigo and tinnitus, soreness of the waist and knees, the asthenia body is thin.Nutritional anemia, iron deficiency anemia belong to above-mentioned patient.Blood replenishing capsule ' Wei Xue Kang ' is with specific prepared, and it is little to have a dose, the characteristics that are easy to carry, transport and preserve.
The specific embodiment
The infantile health-care capsule prescription is as follows:
Radix Codonopsis 60g, Radix Rehmanniae Preparata 80g, Semen sojae atricolor 80g, Rhizoma Dioscoreae 120g, Pericarpium Citri Reticulatae 120g, Fructus Amomi 10g, Radix Polygoni Multiflori 69g, ferrous sulfate 10g, Fructus Crataegi 60g.
Blood replenishing capsule ' Wei Xue Kang ' adopts following method for making:
Get above nine flavor medical materials, except that the ferrous 10g of sulphuric acid, Fructus Amomi 10g, Pericarpium Citri Reticulatae 60g extracts Aromatic water with steam distillation, and is standby; Medicinal residues and remaining Pericarpium Citri Reticulatae 60g and the ginseng 60g of the remaining confederates thereof, Radix Rehmanniae Preparata 80g, Semen sojae atricolor 80g, Rhizoma Dioscoreae 120g, Radix Polygoni Multiflori 69g, Fructus Crataegi 60g Six-element decocts with water secondary, each 2 hours, filters, merging filtrate, and be concentrated in right amount, add ethanol and make and contain the alcohol amount and reach 60%, leave standstill, draw supernatant, reclaim ethanol, put and be chilled to room temperature, filter, filtrate decompression concentrates, and dry, pulverizing adds above-mentioned ferrous sulfate and starch mixing, granulate, spray into Aromatic water, mixing, encapsulated, promptly.
Embodiment
The blood replenishing capsule ' Wei Xue Kang ' recipe quantity is 5 times of infantile health-care capsule syrup recipe quantity, and recipe quantity is as follows:
Radix Codonopsis 300g, Radix Rehmanniae Preparata 400g, Semen sojae atricolor 400g, Rhizoma Dioscoreae 600g, Pericarpium Citri Reticulatae 600g, Fructus Amomi 50g, Radix Polygoni Multiflori 345g, ferrous sulfate 50g, Fructus Crataegi 300g.
Get above nine flavor medical materials, except that the ferrous 50g of sulphuric acid, Fructus Amomi 50g, Pericarpium Citri Reticulatae 300g adds 12 times of water gagings and extracted Aromatic water in 5 hours with the steam distillation distillation, and is standby; Medicinal residues and remaining Pericarpium Citri Reticulatae 300g and the ginseng 300g of the remaining confederates thereof, Radix Rehmanniae Preparata 400g, Semen sojae atricolor 400g, Rhizoma Dioscoreae 600g, Radix Polygoni Multiflori 345g, Fructus Crataegi 300g Six-element, decoct with water secondary, add 10 times of water gagings for the first time, add 8 times of water gagings for the second time, each 2 hours, filter merging filtrate, and be concentrated into the clear paste that relative density is 1.10 (60 ℃ of surveys), and put to room temperature, add ethanol and make and contain alcohol amount and reach 60%, left standstill 24 hours, and drew supernatant, reclaim ethanol, put and be chilled to room temperature, filter, filtrate is at-0.06Mpa, being evaporated to relative density under 70 ℃ the condition is the thick paste of 1.30 (60 ℃ of surveys), then just thick paste at-0.06Mpa, dry under 70 ℃ the condition, pulverize, add above-mentioned ferrous sulfate and starch mixing, with 70% ethanol is wetting agent, and 18 mesh sieves are granulated, 60 ℃ of dryings, 18 mesh sieve granulate, add magnesium stearate 0.4g again, spray into Aromatic water, mixing, airtight 2 hours, encapsulated, make 1000, promptly.
Usage: oral, be grown up one time 4,2 of children's one time, 3 times on the one.

Claims (3)

1, a kind of method for making of blood replenishing capsule ' Wei Xue Kang ', prescription derives from " infantile health-care capsule syrup ", it is characterized in that: blood replenishing capsule ' Wei Xue Kang ' in process of production, except that sulphuric acid was ferrous, the Pericarpium Citri Reticulatae of Fructus Amomi and half amount extracts Aromatic water with steam distillation, and was standby; Medicinal residues and remaining Pericarpium Citri Reticulatae and remaining confederates' ginseng thereof, Radix Rehmanniae Preparata, Semen sojae atricolor, Rhizoma Dioscoreae, Radix Polygoni Multiflori, the Fructus Crataegi Six-element decocts with water secondary, each 2 hours, filters, merging filtrate, and be concentrated in right amount, add ethanol and make and contain the alcohol amount and reach 60%, leave standstill, draw supernatant, reclaim ethanol, put and be chilled to room temperature, filter, filtrate decompression concentrates, and dry, pulverizing adds above-mentioned ferrous sulfate and starch mixing, granulate, spray into Aromatic water, mixing, encapsulated, promptly.
2, the method for making of a kind of blood replenishing capsule ' Wei Xue Kang ' according to claim 1, it is characterized in that: blood replenishing capsule ' Wei Xue Kang ' in process of production, except that sulphuric acid was ferrous, the Pericarpium Citri Reticulatae of Fructus Amomi and half amount adds 8~14 times of water gagings and extracted Aromatic water in 5 hours with the steam distillation distillation, and was standby; Medicinal residues and remaining Pericarpium Citri Reticulatae and remaining confederates' ginseng thereof, Radix Rehmanniae Preparata, Semen sojae atricolor, Rhizoma Dioscoreae, Radix Polygoni Multiflori, Fructus Crataegi Six-element, decoct with water secondary, add 8~12 times of water gagings for the first time, add 6~10 times of water gagings for the second time, each 2 hours, filter merging filtrate, and be concentrated into the clear paste that relative density is 1.05~1.15 (60 ℃), and put to room temperature, add ethanol and make and contain alcohol amount and reach 60%, left standstill 24 hours, and drew supernatant, reclaim ethanol, put and be chilled to room temperature, filter, filtrate is at-0.05~0.095Mpa, and being evaporated to relative density under 50 ℃~100 ℃ the condition is the thick paste of 1.25~1.40 (60 ℃), then with thick paste at-0.06Mpa, dry under 70 ℃ the condition, pulverize, add above-mentioned ferrous sulfate and starch mixing, granulate, spray into Aromatic water, mixing, encapsulated, promptly.
3, the method for making of a kind of blood replenishing capsule ' Wei Xue Kang ' according to claim 1 is characterized in that: blood replenishing capsule ' Wei Xue Kang ' in process of production, except that sulphuric acid was ferrous, the Pericarpium Citri Reticulatae of Fructus Amomi and half amount adds 12 times of water gagings and extracted Aromatic water in 5 hours with the steam distillation distillation, and was standby; Medicinal residues and remaining Pericarpium Citri Reticulatae and remaining confederates' ginseng thereof, Radix Rehmanniae Preparata, Semen sojae atricolor, Rhizoma Dioscoreae, Radix Polygoni Multiflori, Fructus Crataegi Six-element, decoct with water secondary, add 10 times of water gagings for the first time, add 8 times of water gagings for the second time, each 2 hours, filter merging filtrate, and be concentrated into the clear paste that relative density is 1.10 (60 ℃), and put to room temperature, add ethanol and make and contain alcohol amount and reach 60%, left standstill 24 hours, and drew supernatant, reclaim ethanol, put and be chilled to room temperature, filter, filtrate is at-0.06Mpa, being evaporated to relative density under 70 ℃ the condition is the thick paste of 1.30 (60 ℃), then just thick paste at-0.06Mpa, dry under 70 ℃ the condition, pulverize, adding above-mentioned ferrous sulfate and starch mixing, is wetting agent with 70% ethanol, and 18 mesh sieves are granulated, 60 ℃ of dryings, 18 mesh sieve granulate add magnesium stearate again, spray into Aromatic water, mixing, airtight 2 hours, encapsulated, promptly.
CN 200610032119 2006-08-16 2006-08-16 Method for preparing blood replenishing capsule 'Wei Xue Kang' Pending CN1951491A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181590B (en) * 2007-11-23 2010-11-10 包头中药有限责任公司 wei-xue-kang mastication tablet verification method
CN110585321A (en) * 2019-10-14 2019-12-20 黑龙江中医药大学 Traditional Chinese medicine composition for preventing and treating anemia and preparation method and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181590B (en) * 2007-11-23 2010-11-10 包头中药有限责任公司 wei-xue-kang mastication tablet verification method
CN110585321A (en) * 2019-10-14 2019-12-20 黑龙江中医药大学 Traditional Chinese medicine composition for preventing and treating anemia and preparation method and application thereof

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