CN1951208B - 一种动物营养素及其制备方法 - Google Patents
一种动物营养素及其制备方法 Download PDFInfo
- Publication number
- CN1951208B CN1951208B CN2005101182402A CN200510118240A CN1951208B CN 1951208 B CN1951208 B CN 1951208B CN 2005101182402 A CN2005101182402 A CN 2005101182402A CN 200510118240 A CN200510118240 A CN 200510118240A CN 1951208 B CN1951208 B CN 1951208B
- Authority
- CN
- China
- Prior art keywords
- milk
- animal
- humic acid
- dandelion
- animal nutrient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 241001465754 Metazoa Species 0.000 title claims abstract description 32
- 235000015097 nutrients Nutrition 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title abstract description 10
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 12
- 241000245665 Taraxacum Species 0.000 claims abstract description 11
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 9
- ZSBXGIUJOOQZMP-UHFFFAOYSA-N Isomatrine Natural products C1CCC2CN3C(=O)CCCC3C3C2N1CCC3 ZSBXGIUJOOQZMP-UHFFFAOYSA-N 0.000 claims abstract description 8
- ZSBXGIUJOOQZMP-JLNYLFASSA-N Matrine Chemical compound C1CC[C@H]2CN3C(=O)CCC[C@@H]3[C@@H]3[C@H]2N1CCC3 ZSBXGIUJOOQZMP-JLNYLFASSA-N 0.000 claims abstract description 8
- 229930014456 matrine Natural products 0.000 claims abstract description 8
- 239000002509 fulvic acid Substances 0.000 claims description 26
- PUKLDDOGISCFCP-JSQCKWNTSA-N 21-Deoxycortisone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)C)(O)[C@@]1(C)CC2=O PUKLDDOGISCFCP-JSQCKWNTSA-N 0.000 claims description 25
- FCYKAQOGGFGCMD-UHFFFAOYSA-N Fulvic acid Natural products O1C2=CC(O)=C(O)C(C(O)=O)=C2C(=O)C2=C1CC(C)(O)OC2 FCYKAQOGGFGCMD-UHFFFAOYSA-N 0.000 claims description 25
- 229940095100 fulvic acid Drugs 0.000 claims description 25
- 239000009636 Huang Qi Substances 0.000 claims description 7
- 208000004396 mastitis Diseases 0.000 abstract description 31
- QJZYHAIUNVAGQP-UHFFFAOYSA-N 3-nitrobicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid Chemical compound C1C2C=CC1C(C(=O)O)C2(C(O)=O)[N+]([O-])=O QJZYHAIUNVAGQP-UHFFFAOYSA-N 0.000 abstract description 10
- 239000004021 humic acid Substances 0.000 abstract description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract description 9
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract description 5
- 230000003213 activating effect Effects 0.000 abstract description 5
- 239000003245 coal Substances 0.000 abstract description 4
- 239000002131 composite material Substances 0.000 abstract description 4
- 238000001035 drying Methods 0.000 abstract description 3
- 238000002156 mixing Methods 0.000 abstract description 2
- 229940107666 astragalus root Drugs 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002893 slag Substances 0.000 abstract 1
- 235000011121 sodium hydroxide Nutrition 0.000 abstract 1
- 239000008267 milk Substances 0.000 description 37
- 210000004080 milk Anatomy 0.000 description 37
- 235000013336 milk Nutrition 0.000 description 37
- 241000283690 Bos taurus Species 0.000 description 28
- 230000000694 effects Effects 0.000 description 15
- 241000411851 herbal medicine Species 0.000 description 14
- 239000000284 extract Substances 0.000 description 10
- 201000010099 disease Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 6
- 230000003115 biocidal effect Effects 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- 239000002253 acid Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- 235000013365 dairy product Nutrition 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 230000001937 non-anti-biotic effect Effects 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 206010006262 Breast inflammation Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 241000194017 Streptococcus Species 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000000481 breast Anatomy 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 230000002147 killing effect Effects 0.000 description 2
- 239000003077 lignite Substances 0.000 description 2
- 235000014666 liquid concentrate Nutrition 0.000 description 2
- 210000005075 mammary gland Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000005416 organic matter Substances 0.000 description 2
- 239000003415 peat Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000273 veterinary drug Substances 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 102000030523 Catechol oxidase Human genes 0.000 description 1
- 108010031396 Catechol oxidase Proteins 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000710198 Foot-and-mouth disease virus Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 208000008469 Peptic Ulcer Diseases 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 240000001949 Taraxacum officinale Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 210000004404 adrenal cortex Anatomy 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000001760 anti-analgesic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- -1 aromatic carboxylic acids Chemical class 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000032823 cell division Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000000536 complexating effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000002389 essential drug Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229940102223 injectable solution Drugs 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 235000014058 juice drink Nutrition 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000033116 oxidation-reduction process Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000000242 pagocytic effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 208000011906 peptic ulcer disease Diseases 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Images
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Fodder In General (AREA)
Abstract
本发明公开了一种动物营养素及其制备方法，主要技术特征是它由黄腐植酸、蒲公英、金银花、黄芪、苦参碱配制而成，其制备方法是将风化煤粉碎，按比例加氢氧化钠溶液，提取液经离心分离除渣，并用双氧水活化，加复合沉淀剂沉淀并分离去除棕、黑腐植酸，将沉清液浓缩干燥，即得pH≤7的饲料级黄腐植酸。将精选并干燥粉碎的蒲公英、金银花、黄芪与饲料级黄腐植酸及苦参碱按比例混匀，即得动物营养素成品。本动物营养素配比独特、制备工艺合理，有很高的药用功能。它对奶牛乳房炎及隐性乳房炎、对消化性溃疡，均有良好的防治效果，并可使奶牛的产奶量显著提高。
Description
技术领域
本发明涉及一种动物营养素及其制备方法，特别指以黄腐植酸和中药材及中药材提取物为原料制备的动物营养素及其制备方法。
背景技术
在奶牛饲养中，各种类型的乳房炎是发病率高、流行快、造成损失最大的一种疾病。一些国家对此病已进行了多年的研究，但至今未能提出一个彻底的解决办法。目前全世界约有奶牛2.2亿头，据统计约有1/3的奶牛患有各种类型的乳房炎和隐性乳房炎。因乳房炎造成的经济损失高达350亿美元以上。2003年末，全国奶牛约有890万头。而我国奶牛乳房炎发病率普遍高于国外，患病率在50％以上。奶牛患乳房炎后，产奶量约下降20％左右，这种疾病每年造成的损失约几十亿人民币，损失惊人。各类奶牛乳房炎困扰着我国乳业的发展，严重影响奶牛养殖业的经济效益。自上世纪40年代抗生素问世以来，抗生素一直是控制各类奶牛乳房炎症的基本药物，然而疗效日趋降低，致病菌对抗生素的耐药性日趋严重，出现了多重耐药菌株。而牛奶中抗生素的残留给人类、动物后代的健康也带来极大的危害，乳制品的安全性已受到国家有关部门和广大消费者的关注。
目前，非抗生素疗法已成为国内外学者研究奶牛乳房炎防治的热点。非抗生素疗法即是通过调节乳腺的免疫机能，增强机体对病原微生物的抵抗力，减少乳腺感染来防治奶牛乳房炎。腐植酸是从泥炭、褐煤及风化煤中提取出来的天然芳香羧酸类大分子活性有机物。腐植酸在畜牧业上的应用研究我国始于上个世纪70年代，腐植酸对防治奶牛乳房炎已取得了良好的应用效果。中草药在医药、兽药中的应用历史悠久，效果显著。中草药及其活性成份如多糖、皂甙等在调节乳腺免疫机能方面具有良好作用和潜力，亟需进一步研究发掘。
发明内容
本发明要解决的技术问题是提供一种动物营养素及其制备方法，这种动物营养素是以黄腐植酸、中草药及中草药的提取物为原料加以科学复合制备的。用本方法制备出的动物营养素拌入饲料中饲喂奶牛，成为对奶牛乳房炎很有效的非抗生素疗法。它可避免使用抗生素带来的许多弊病。
本发明的技术问题是由如下方案解决的：本动物营养素由黄腐植酸、蒲公英、金银花、黄芪、苦参碱5种组分配制而成，各组分所占总重量百分比为黄腐植酸35-45％、蒲公英20-30％、金银花20-30％、黄芪10-15％、苦参碱1-2％。
本动物营养素的制备方法是：将风化煤粉碎至≤60目，按1∶8-10的重量比加入浓度为2％-4％的氢氧化钠溶液，于60℃-80℃提取2h-3h，提取液经离心分离除渣后，按100∶1-2的重量比加入浓度为30％的双氧水，于70℃-80℃活化1.5h-2h成活化液，以上述每1M活化液加50L-80L由1mol/L的盐酸溶液与0.2‰的PAM溶液以10∶1-3的体积比复合而成的复合沉淀剂沉淀并分离去除棕、黑腐植酸，将沉清液浓缩干燥，得PH≤7的饲料级黄腐植酸及其盐，取精选并干燥的蒲公英、金银花、黄芪分别粉碎至≤40目，与≤40目的饲料级黄腐植酸、苦参碱用混合机按上述比例均匀混合，即得动物营养素成品。
本发明的优点是：本动物营养素的基础原料是饲料级黄腐植酸、中草药及提取物。将黄腐植酸与遴选的中草药经科学复合配伍，增强了防治奶牛乳房炎及隐性乳房炎等病患的作用。
本发明根据奶牛的生理特点和乳房炎症的发病规律及遗传因素、环境因素、畜群管理因素等，研究了饲料级黄腐植酸，并根据中医兽医药理论，依照传统古方与现代动医理论，遴选了有效中草药。经提取浓缩和粉碎至细粉，与黄腐植酸科学复配，制成纯天然功能性饲料添加剂——动物营养素。黄腐植酸是腐植酸中的精华，它是腐植酸经转化和分离(分离掉其中的棕腐酸、黑腐酸)精制提取的含有多种活性基团、具有较强生理活性、溶于水和弱酸、分子量较小的弱有机酸。黄腐植酸在畜牧业方面的应用是近几年开始的，这种天然活性有机物作为奶牛饲料添加剂的新秀，能够增强奶牛机体免疫力、防治奶牛乳房炎。它的功效已引起了国内外高度重视，并已大力研究开发和推广。
黄腐植酸是动物营养素的主要成分，用于畜牧业功能独特，效果显著，它可以起到以下6个方面的作用。
1、促进生长：由于分子中含有大量的含氧基团及酚-醌结构参与机体的氧化还原过程，它可起到吊调节甲状腺功能、抑制ATP酶对ATP的分解、促进细胞氧化磷化、激活己糖酶、促进葡萄糖在机体内的吸收和利用、提高转化率及新陈代谢旺盛、细胞分裂加速的作用。
2、消炎止痛作用：黄腐植酸对肾上腺皮质有活化作用，能促进肾上腺素和促进肾上腺皮质激素的分泌，因而有消炎和止痛作用。
3、增强肌体免疫功能：增强体内的多酚氧化酶、过氧化酶、抗坏血酸氧化酶等多种酶的活性，同时激活单核巨噬细胞系统，提高机体外围血白细胞的吞噬指数，使其具有增强肌体免疫活性细胞和机体免疫系统的排异能力，使肌体抗病能力提高。
4、止血作用：黄腐植酸能增加血小板的数量，并使血管收缩，降低毛细血管的通透性，因而起到止血作用。
5、改善肠胃功能：黄腐植酸进入消化道后，可刺激胃壁粘膜增加胃液分泌，增加食欲。又因黄腐植酸具有表面活性，能促进营养物更快进入肌体，提高吸收率和转化率；还能刺激动物胃肠中有益微生物的生长，抑制腐败菌的繁殖，防止牛胃酸中毒。黄腐植酸有较强的吸附和络合力，能有效吸附肠胃中有毒有害物质和细菌毒素，具有解毒、减轻排泻物臭味和明显的收敛止泻作用，有利于圈养舍饲环境的改善。
6、抗菌抗病毒作用：在各种酶的作用下，黄腐植酸分子中的活性基团可分解出初生态氧，因而呈现杀菌作用。对于一些病毒，如口蹄疫病毒也有杀灭作用。
黄腐植酸对抗肿瘤、对奶牛乳房炎及隐性乳房炎、对消化性溃疡，均有良好的防治效果，并可使奶牛的产奶量显著提高。
中草药在奶牛乳房炎及隐性乳房炎的防治中亦多有应用。传统兽医学理论认为，奶牛遭受外界风寒、潮湿的影响，侵袭经络及血脉，气滞不前，气滞则血淤，再加上乳汁蓄积，所以乳房出现红肿发热，乳痈热毒，血液乳汁不通畅，蕴积于乳房内生热，久而结聚成乳痈--即乳房炎。
现代动物医学理论认为，微生物感染是引起各类奶牛乳房炎的主要原因。传染病原体和环境性病原体中，以金黄色葡萄球菌、链球菌和大肠杆菌为主，约占整个奶牛乳房炎病例的90％。
在本动物营养素的研发过程中，将传统兽医学理论和现代动物医学理论结合，遴选中草药及其提取物。如据《本草纲目》蒲公英项目介绍：“妇人乳痈肿，水煮汁饮封之，立消”。据蒲公英注射液试管内试验，其对金黄色葡萄球菌耐药菌株、溶血性链球菌有较强的杀灭作用。为此，在动物营养素的复配及中草药遴选中，蒲公英作为首选并和其它抗菌消炎、败火的多年生中草药配伍，确定为动物营养素的中草药成分。
将上述中草药及中草药提取物与饲料级黄腐植酸按比例复配，制成了粉状产品动物营养素。
本动物营养素与抗生素比较：一是使用方便，无需注射器及其它医疗器具，只需按比例将动物营养素拌入饲料中饲喂即可，省时、省事、省人力、省医疗费用。二是黄腐植酸与遴选的中草药科学复合配伍，相得益彰，取得了独特的防治效果，大幅度降低了乳房炎及隐性乳房炎的治疗成本。三是奶牛日产奶量增加0.83-1.89公斤。
试验结果如下：
1、牛奶质量提高，牛奶中的体细胞由试前的平均值1012万个/ML降到试验后的37万个/ML，显著的提高了牛奶的质量。
2、奶产量提高
饲喂60天后，试验组产奶量较对照组平均增加0.83公斤/日·头；饲喂90天后，与对照组比较产奶量增加1.89公斤/日·头。
3、有效产奶期增长
经测算，饲喂本动物营养素，可延长奶牛泌乳期约36-39天。动物营养素对奶牛的乳房炎及隐性乳房炎的防治及奶乳的产、质量提高有显著效果。
附图说明
附图是本发明动物营养素制备工艺流程框图
具体实施方式
实施例：将风化煤(泥炭或褐煤)粉碎至60目，按1∶10的重量比加入浓度为3％的氢氧化钠溶液，于60℃提取2h，提取液经离心分离除渣后，再按100∶1的重量比加入浓度为30％的双氧水，于70℃活化1.5h成活化液，再由1mol/L的盐酸溶液与0.2‰的PAM溶液以10∶2的体积比复合成复合沉淀剂，以上述每1M活化液加70L的比例加复合沉淀剂沉淀并分离去除棕、黑腐植酸，将沉清液浓缩干燥，得PH＝6.8的饲料级黄腐植酸及盐，再取精选并干燥的蒲公英、金银花、黄芪分别粉碎至40目，称取粉碎好的蒲公英0.65千克、金银花0.65千克、黄芪0.34千克与40目的饲料级黄腐植酸1千克、40目的苦参碱0.03千克用混合机按上述比例混匀，即得动物营养素成品。
Claims (1)
1.一种动物营养素，其特征是：它由黄腐植酸、蒲公英、金银花、黄芪、苦参碱5种组分配制而成，各组分所占总重量百分比为黄腐植酸35-45％、蒲公英20-30％、金银花20-30％、黄芪10-15％、苦参碱1-2％。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2005101182402A CN1951208B (zh) | 2005-10-21 | 2005-10-21 | 一种动物营养素及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2005101182402A CN1951208B (zh) | 2005-10-21 | 2005-10-21 | 一种动物营养素及其制备方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1951208A CN1951208A (zh) | 2007-04-25 |
| CN1951208B true CN1951208B (zh) | 2010-09-08 |
Family
ID=38057927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2005101182402A Active CN1951208B (zh) | 2005-10-21 | 2005-10-21 | 一种动物营养素及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1951208B (zh) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102113632B (zh) * | 2009-12-31 | 2013-01-23 | 内蒙古伊利实业集团股份有限公司 | 一种预防奶牛隐性乳房炎的功能性奶牛饲料添加剂 |
| CN101999556B (zh) * | 2010-12-08 | 2012-11-14 | 内蒙古永业农丰生物科技有限责任公司 | 肉牛专用型动物营养素及其制备方法 |
| CN101999554B (zh) * | 2010-12-08 | 2013-04-17 | 内蒙古永业农丰生物科技有限责任公司 | 奶牛专用型动物营养素及其制备方法 |
| CN101999555B (zh) * | 2010-12-08 | 2013-01-16 | 内蒙古永业农丰生物科技有限责任公司 | 羊专用型动物营养素及其制备方法 |
| CN102669485B (zh) * | 2012-06-11 | 2013-11-06 | 内蒙古永业农丰生物科技有限责任公司 | 肉鸡专用型动物生命素及其制备方法 |
| CN102669487B (zh) * | 2012-06-11 | 2013-11-06 | 内蒙古永业农丰生物科技有限责任公司 | 猪专用型动物生命素及其制备方法 |
| CN104757277A (zh) * | 2014-01-03 | 2015-07-08 | 黄宝库 | 具有促长排毒提质作用的棕腐酸钠物质 |
| CN105166451A (zh) * | 2015-08-06 | 2015-12-23 | 钱峰 | 一种防治乳房炎的奶牛饲料 |
| CN106924405A (zh) * | 2017-03-23 | 2017-07-07 | 南宁学院 | 一种防治奶牛乳房炎的组合物及其制备方法 |
-
2005
- 2005-10-21 CN CN2005101182402A patent/CN1951208B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN1951208A (zh) | 2007-04-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1951208B (zh) | 一种动物营养素及其制备方法 | |
| CN102239972B (zh) | 用于提高断奶仔猪免疫力及抗寄生虫感染的中药饲料添加剂及其制备和使用方法 | |
| CN103141702B (zh) | 一种可有效防治猪流行性腹泻的中草药提取物饲料添加剂 | |
| CN106177339A (zh) | 一种制备治疗痛风草本植物制剂的方法 | |
| CN111000892A (zh) | 一种用于提高家禽产蛋率的复合型添加剂及其制备方法和应用 | |
| CN102836367B (zh) | 一种抗菌消炎止痒的中药组合物及其制备方法和应用 | |
| CN108771242A (zh) | 一种冠突散囊菌发酵功能复合物及其制备方法和应用 | |
| CN102640864A (zh) | 提高鸡免疫力预防腹泻的中草药饲料添加剂及其使用方法 | |
| CN105410346A (zh) | 提高养殖对虾存活率的中药制剂及其制备方法 | |
| CN101744924B (zh) | 大菱鲆细菌性疾病的中草药复方 | |
| CN101999554B (zh) | 奶牛专用型动物营养素及其制备方法 | |
| CN112772681B (zh) | 一种生物复合型消毒剂及其制备方法 | |
| CN104971161A (zh) | 藤茶提取物的痤疮治疗用途 | |
| CN109646546B (zh) | 一种用于防治牲畜腹泻的中药组合物及其制备方法 | |
| CN112043730A (zh) | 一种防治动物疫病的中药生物制剂 | |
| CN106344523A (zh) | 一种虎杖苷磷脂复合物颗粒剂的制备方法与应用 | |
| CN102793869B (zh) | 一种用于防治猪病毒性疾病的中药组合物及其制备方法 | |
| KR102033214B1 (ko) | 소화 흡수 촉진으로 아토피에 유효한 식품 첨가제, 그 제조방법과 이를 첨가한 식품 | |
| CN101711818A (zh) | 一种防治畜禽呼吸道疾病的天然植物制剂及其制备方法 | |
| CN105287734A (zh) | 一种具有抗菌作用的中药材纸张及其制备方法 | |
| CN102008693B (zh) | 含天然珊瑚姜精油的润喉消炎含片 | |
| CN101744866B (zh) | 防治畜禽养殖疾病的中药组合物及其制备方法、应用 | |
| CN111281922B (zh) | 一种用于治疗猪禽腹泻的复方中兽药口服制剂及其制备方法 | |
| CN1261103C (zh) | 一种抗癌用微生物原料药、其生产方法及其用途 | |
| CN108653422B (zh) | 一种治疗仔猪腹泻的中草药制剂及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: INNER INNER MONGOLIA YONGFENG AGRICULTURAL BIOTEC Free format text: FORMER OWNER: NEIMENGGUYONGYE BIOLOGY TECHNOLOGY CO., LTD. Effective date: 20080613 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20080613 Address after: Jinshan Development Zone Hohhot city the Inner Mongolia Autonomous Region Jinshan Avenue Yongye Biological Park Post encoding: 010080 Applicant after: Inner Mongolia Yongye Nongfeng Biotechnology Co.,Ltd. Address before: Jinshan Development Zone Hohhot city the Inner Mongolia Autonomous Region Jinshan Avenue Yongye Biological Park Post encoding: 010080 Applicant before: INNER MONGOLIA YONGYE BIO-TECHNOLOGY CO.,LTD. |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Nutrient for animal and preparation process thereof Effective date of registration: 20140314 Granted publication date: 20100908 Pledgee: China Everbright Bank Limited by Share Ltd. Hohhot branch Pledgor: Inner Mongolia Yongye Nongfeng Biotechnology Co.,Ltd. Registration number: 2014990000162 |
|
| PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
| PP01 | Preservation of patent right |
Effective date of registration: 20160907 Granted publication date: 20100908 |
|
| RINS | Preservation of patent right or utility model and its discharge | ||
| PD01 | Discharge of preservation of patent |
Date of cancellation: 20170307 Granted publication date: 20100908 |
|
| PD01 | Discharge of preservation of patent | ||
| PP01 | Preservation of patent right |
Effective date of registration: 20170307 Granted publication date: 20100908 |
|
| PP01 | Preservation of patent right | ||
| PD01 | Discharge of preservation of patent |
Date of cancellation: 20170907 Granted publication date: 20100908 |
|
| PD01 | Discharge of preservation of patent | ||
| PP01 | Preservation of patent right |
Effective date of registration: 20170907 Granted publication date: 20100908 |
|
| PP01 | Preservation of patent right | ||
| PD01 | Discharge of preservation of patent |
Date of cancellation: 20230907 Granted publication date: 20100908 |
|
| PD01 | Discharge of preservation of patent | ||
| PP01 | Preservation of patent right |
Effective date of registration: 20230907 Granted publication date: 20100908 |
|
| PP01 | Preservation of patent right |