CN1942578A - 表达禽流感病毒H5亚型HA蛋白的重组新城疫LaSota弱毒疫苗株 - Google Patents

表达禽流感病毒H5亚型HA蛋白的重组新城疫LaSota弱毒疫苗株 Download PDF

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CN1942578A
CN1942578A CNA2006800000240A CN200680000024A CN1942578A CN 1942578 A CN1942578 A CN 1942578A CN A2006800000240 A CNA2006800000240 A CN A2006800000240A CN 200680000024 A CN200680000024 A CN 200680000024A CN 1942578 A CN1942578 A CN 1942578A
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attenuated vaccine
rlasota
virus
new castle
vaccine strain
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CN1942578B (zh
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步志高
陈化兰
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Harbin Veterinary Research Institute of CAAS
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Harbin Veterinary Research Institute of CAAS
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Priority claimed from CNB2005100979963A external-priority patent/CN1298845C/zh
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Abstract

本发明涉及一种表达野生型或突变型禽流感病毒H5亚型血凝素(HA)蛋白的重组新城疫LaSota弱毒疫苗株，更具体地，重组新城疫LaSota弱毒疫苗株是rLasota－H5wtHA和rLasota－H5mutHA。本发明还公开了制备所述重组新城疫LaSota弱毒疫苗株的方法和该重组新城疫LaSota弱毒疫苗株在制备预防禽流感的疫苗中的应用。

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PCT国内申请，说明书已公开。

Claims (1)

  1. PCT国内申请，权利要求书已公开。
CN2006800000240A 2005-09-02 2006-01-13 表达禽流感病毒H5亚型HA蛋白的重组新城疫LaSota弱毒疫苗株 Active CN1942578B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2006800000240A CN1942578B (zh) 2005-09-02 2006-01-13 表达禽流感病毒H5亚型HA蛋白的重组新城疫LaSota弱毒疫苗株

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN200510097996.3 2005-09-02
CNB2005100979963A CN1298845C (zh) 2005-09-02 2005-09-02 表达禽流感病毒H5亚型HA蛋白的重组新城疫LaSota弱毒疫苗株
PCT/CN2006/000056 WO2007025420A1 (fr) 2005-09-02 2006-01-13 Souche de faible virulence du vaccin recombinant lasota de la maladie de newcastle exprimant la protéine ha du virus h5 de la grippe aviaire
CN2006800000240A CN1942578B (zh) 2005-09-02 2006-01-13 表达禽流感病毒H5亚型HA蛋白的重组新城疫LaSota弱毒疫苗株

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CN1942578A true CN1942578A (zh) 2007-04-04
CN1942578B CN1942578B (zh) 2011-06-15

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CN2006800000240A Active CN1942578B (zh) 2005-09-02 2006-01-13 表达禽流感病毒H5亚型HA蛋白的重组新城疫LaSota弱毒疫苗株

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106085970A (zh) * 2016-06-15 2016-11-09 湖北省农业科学院畜牧兽医研究所 表达信号肽替换的h5亚型禽流感ha蛋白的重组新城疫耐热疫苗株及制备方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105950572A (zh) * 2016-06-15 2016-09-21 湖北省农业科学院畜牧兽医研究所 表达h5亚型禽流感病毒截短ha蛋白的重组新城疫耐热疫苗株及制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1261564C (zh) * 2003-12-02 2006-06-28 中国农业科学院哈尔滨兽医研究所 人工重组的流感病毒及其应用
CN1298845C (zh) * 2005-09-02 2007-02-07 中国农业科学院哈尔滨兽医研究所 表达禽流感病毒H5亚型HA蛋白的重组新城疫LaSota弱毒疫苗株

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106085970A (zh) * 2016-06-15 2016-11-09 湖北省农业科学院畜牧兽医研究所 表达信号肽替换的h5亚型禽流感ha蛋白的重组新城疫耐热疫苗株及制备方法
CN106085970B (zh) * 2016-06-15 2019-04-12 湖北省农业科学院畜牧兽医研究所 表达信号肽替换的h5亚型禽流感ha蛋白的重组新城疫耐热疫苗株及制备方法

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