CN1939523A - Chinese-medicinal preparation for treating hysteromyoma and its making method - Google Patents

Chinese-medicinal preparation for treating hysteromyoma and its making method Download PDF

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CN1939523A
CN1939523A CNA2006100961606A CN200610096160A CN1939523A CN 1939523 A CN1939523 A CN 1939523A CN A2006100961606 A CNA2006100961606 A CN A2006100961606A CN 200610096160 A CN200610096160 A CN 200610096160A CN 1939523 A CN1939523 A CN 1939523A
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chinese
hysteromyoma
chinese medicine
hirudo
treatment
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CN100531787C (en
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吉慧文
王永铿
陆光裕
林金镐
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Yongding Caishantang Medicine Industry Co ltd
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Abstract

A Chinese medicine for treating hysteromyoma with high curative effect and no toxic by-effect and its preparing process are disclosed.

Description

A kind of Chinese medicine preparation for the treatment of hysteromyoma and preparation method thereof
Technical field
What the present invention relates to is a kind of pharmaceutical preparation and preparation method thereof, especially a kind of preparation method for the treatment of the Chinese medicine preparation and the said preparation of hysteromyoma.
Background technology
Hysteromyoma is the female reproductive system most common tumor.Clinical symptoms such as menorrhagia, menostaxis, the cycle is short or abnormal vaginal bleeding, stomachache, infertile or repeatedly miscarriage, anemia, very then cancerate etc. serious harm women's physical and mental health.The means of treatment hysteromyoma have operative treatment and Drug therapy at present.Operative treatment can bring wound and related complication to the patient, and is particularly unmarried or do not educate the patient and more be difficult to accept.And in the Drug therapy, Western medicine adopts treatments such as progestogen, androgen more, though control the growth of muscular tumor to a certain extent, can produce harmful effect to liver, renal function.Also produce side effect such as degrees of osteoporotic, atherosclerosis.For many years, the world of medicine just is being devoted to develop the Chinese medicine preparation of the little treatment hysteromyoma of good effect, side effect, though at present just like Chinese patent medicines commonly used such as GUIZHI FULING JIAONANG and GONGLIUQING capsule, kind is very few, can not satisfy social needs.
Summary of the invention
The purpose of this invention is to provide the little Chinese medicine preparation of a kind of effective treatment hysteromyoma and side effect and the preparation method of said preparation.
Purpose of the present invention is achieved through the following technical solutions.
A kind of Chinese medicine preparation for the treatment of hysteromyoma, it contains following parts by weight of Chinese traditional medicine material:
Semen Persicae 8-12, Rhizoma Curcumae 8-12, rhizoma sparganic 8-12, Hirudo 2-4, Pseudobulbus Cremastrae Seu Pleiones 8-12, Spica Prunellae 8-12, Olibanum 4-8, Myrrha 4-8.
Said preparation can add following parts by weight of Chinese traditional medicine material: Carapax Trionycis (processed with vinegar) 13-17, Radix Linderae 8-12, Herba Leonuri 8-12, Radix Bupleuri 6-10.
Said preparation also can add following parts by weight of Chinese traditional medicine material again: Radix Astragali 13-17, Radix Angelicae Sinensis 6-10, Herba Cistanches 8-12.
The preparation method of this Chinese medicine preparation is:
It is standby to get Chinese crude drug by above-mentioned weight portion; Hirudo is worn into fine powder separately; Other Chinese crude drug is mixed the back extracting in water repeatedly, filter merging filtrate; Filtrate is concentrated, heats; Add clarifier and stir, place, filter; Filtrate is concentrated into thick paste, wears into fine powder after the drying; Add the Hirudo fine powder, stir evenly, make dosage form at last.
This preparation has effects such as good blood circulation promoting and blood stasis dispelling, hard masses softening and resolving through the science compatibility.The preparation technology of said preparation is reasonable, does not destroy the effective ingredient of each raw material of Chinese medicine, proves through scientific experimentation, and is evident in efficacy to the treatment of hysteromyoma, has no side effect.And this preparation is base stock with the Chinese crude drug, and its resource is very abundant.Therefore this preparation has very high using value and very big DEVELOPMENT PROSPECT.
The specific embodiment
Below in conjunction with embodiment the present invention is further described in detail.
The traditional Chinese medical science thinks that it mainly is owing to plain body weakness, through the row puerperal asthenia that hysteromyoma forms, experience the cold-evil again, objective in the cold-evil goes in uterus, or stagnation of liver-QI void causes depression of liver-QI, spleen fortune is lost strong, no resource of generating and transforming QI and blood finally causes qi stagnation blood stasis or blood stagnancy due to deficiency of QI, the congestion uterus that condenses, the retardance vessels of the uterus, dash to appoint impaired, fresh blood must not return through, with the passing of time form.Therefore, focus on QI and blood liver spleen kidney in the treatment, blood circulation promoting and blood stasis dispelling, Xiao Disorder eliminating stagnation, soothing the liver circulation of qi promoting, heat-clearing and toxic substances removing, by QI invigorating tonifying YIN, nourishing blood for regulating menstruation reach abolish gather, Yu San Disorder disappears, dredge the meridian passage, gas are transferred along blood, dash and appoint an effect of filling Shengs, recovery function.
The record of the performance effect that known following each Chinese medicine has:
1, Semen Persicae: contain amygdaloside, emulsin, vitamin B1 and significant quantities of fat wet goods.Mildly bitter flavor.Function: blood circulation promoting and blood stasis dispelling.Cure mainly: blood stasis amenorrhea, dysmenorrhea, swelling and pain due to blood stasis.
2, Rhizoma Curcumae: hot, bitter, temperature.Return liver, spleen channel.Function: circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.Cure mainly: mass in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.
3, rhizoma sparganic: hot, bitter, flat.Return liver, spleen channel.Function: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.Cure mainly: tumor abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain.
4, Hirudo: salty, bitter, flat.Return Liver Channel.Function: removing blood stasis, removing blood stasis, stimulate the menstrual flow.Cure mainly: mass in the abdomen mass in the abdomen, the blood stasis amenorrhea.
5, Pseudobulbus Cremastrae Seu Pleiones: sweet, little suffering, cold.Return liver, spleen channel.Function: heat-clearing and toxic substances removing, dissipating phlegm and resolving masses.Cure mainly: carbuncle is treated poison, scrofula sucutaneous nodule, tuberculous lymphadenitis.
6, Spica Prunellae: hot, bitter, cold.Return liver, gallbladder meridian.Function: liver heat removing makes eye bright eliminating stagnation, detumescence.Cure mainly: conjunctival congestion and swelling pain, scrofula, goiter, acute mastitis swells and ache; Tuberculous lymphadenitis, cyclomastopathy.
7, Olibanum: hot, bitter, temperature.GUIXIN, liver, spleen channel.Function: blood-activating and qi-promoting, eliminating stasis to stop pain detumescence.Cure mainly: the carbuncle skin ulcer swells and ache.
8, Myrrha: bitter, flat.GUIXIN, liver, spleen channel.Function: promoting blood circulation and stopping pain, detumescence and promoting granulation.Cure mainly: pain due to blood stasis, amenorrhea, mass in the abdomen, the diabrosis of carbuncle skin ulcer cancer are not closed up for a long time.
9, Carapax Trionycis: salty, cold.Return liver, kidney channel.Function: have nourishing YIN for suppressing the hyperactive YANG, the hard masses softening and resolving effect.Cure mainly: fever due to yin deficiency, hectic fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea.
10, the Radix Linderae: suffering, temperature.Function: pleasant pain relieving, warming kidney for dispelling cold.Cure mainly: chest and abdomen swelling and pain, deficiency-cold in the urinary bladder, enuresis frequent micturition, hernia, dysmenorrhea.
11, Herba Leonuri: bitter, hot, be slightly cold.Return liver, pericardium channel.Function: promoting blood flow to regulate menstruation, inducing diuresis to remove edema.Cure mainly: menoxenia, dysmenorrhea, amenorrhea, lochiorrhea.
12, Radix Bupleuri: hardship is slightly cold.Return liver, gallbladder meridian.Function: evacuate and bring down a fever soothing liver-QI, yang invigorating.Cure mainly:, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus.
13, the Radix Astragali: sweet in the mouth, tepor.Function: invigorating QI to consolidate the body surface resistance, the effect of holder skin ulcer granulation promoting, diuretic.Cure mainly: diseases such as deficient qi and blood, uterine prolapse, nephritis edema, chronic ulcer.
14: Radix Angelicae Sinensis: sweet in the mouth, suffering, warm in nature.Return liver, the heart, spleen channel.Function: enrich blood, invigorate blood circulation, regulating menstruation.Cure mainly: blood deficiency or blood deficiency and have the menoxenia that the stasis of blood stagnates concurrently, dysmenorrhea, diseases such as amenorrhea.
15: Herba Cistanches: sweet, salty, temperature.Return kidney, large intestine channel.Function: kidney-replenishing, benefiting essence-blood.Cure mainly the: mass in the abdomen, metrorrhagia, leukorrhagia pain over the perineum.
This Chinese medicine preparation comprises following parts by weight of Chinese traditional medicine material:
Semen Persicae 8-12, Rhizoma Curcumae 8-12, rhizoma sparganic 8-12, Hirudo 2-4, Pseudobulbus Cremastrae Seu Pleiones 8-12, Spica Prunellae 8-12, Olibanum 4-8, Myrrha 4-8.Optimum weight part is: Semen Persicae 10, Rhizoma Curcumae 10, rhizoma sparganic 10, Hirudo 3, Pseudobulbus Cremastrae Seu Pleiones 10, summer are withered 10, Olibanum 6, Myrrha 6.
More than be monarch, ministerial drug, invigorate blood circulation drop-down removing blood stasis and smooth QI and blood and tissue regeneration promoting of monarch drug wherein; Ministerial drug in the resolving phlegm and softening hard masses dispersing accumulated pathogens to resolve the mass, the principal drug assistance blood circulation promoting and blood stasis dispelling.
This Chinese medicine preparation can add following parts by weight of Chinese traditional medicine material:
Carapax Trionycis 13-17, Radix Linderae 8-12, Herba Leonuri 8-12, Radix Bupleuri 6-10.Optimum weight part is: Carapax Trionycis 15, the Radix Linderae 10, Herba Leonuri 10, Radix Bupleuri 8.
This is an adjuvant drug, and the monarch and his subjects Yu Xiao Disorder that dispels is helped in the nourishing YIN and clearing away heat circulation of qi promoting altogether.
This Chinese medicine preparation also can add following parts by weight of Chinese traditional medicine material again:
Radix Astragali 13-17, Radix Angelicae Sinensis 6-10, Herba Cistanches 8-12.Optimum weight part is: the Radix Astragali 15, Radix Angelicae Sinensis 8, Herba Cistanches 10.
This is a messenger drug, and benefiting QI and nourishing blood fills to contain to dash and appoints, and residence is attacked in benefit.
This medicine is according to herbal pharmacology, and the science compatibility has the drop-down of invigorating blood circulation removing blood stasis and smooth QI and blood and tissue regeneration promoting, and the effect of softening and eliminating sputum eliminating stagnation reaches and suppresses and the elimination hysteromyoma, has no side effect.
The preparation method of this Chinese medicine preparation is:
1) takes by weighing Chinese crude drug by above-mentioned weight portion;
2) it is standby the Chinese crude drug Hirudo to be worn into fine powder separately;
3) with adding 8-12 times of water extraction 2-3 time after other Chinese crude drug mixing, each 1-2 hour, filter merging filtrate;
4) filtrate is concentrated into 1: the 4-6 medicinal liquid;
5) with 70 ℃-90 ℃ of medicinal liquid heating, add clarifier and stir, placed 2-3 hour;
6) add clarifier again and stir, place more than 5 hours, filter;
7) filtrate is concentrated into thick paste, wears into fine powder after the drying;
8) add the Hirudo fine powder, stir evenly, make dosage form at last.
Its main constituent of described clarifier is a chitosan, the natural clarifying agent ZTC1+1 that can use Tianjin to become clarifier technology company limited to produce in positive day.
The described dosage form of making can be made into capsule, tablet, granule, pill etc.
Most preferred embodiment:
Water intaking trematodiasis 120 grams are worn into 200 order fine powders separately, and are standby; Get Semen Persicae 400 grams, rhizoma sparganic 400 grams, Rhizoma Curcumae 400 grams, Pseudobulbus Cremastrae Seu Pleiones 400 grams, Spica Prunellae 400 grams, Olibanum 240 grams, Myrrha 240 grams, Carapax Trionycis 600 grams, the Radix Linderae 400 grams, Herba Leonuri 400 grams, Radix Bupleuri 320 grams, the Radix Astragali 600 grams, Radix Angelicae Sinensis 320 grams, Herba Cistanches 400 grams, add 10 times of water extraction 2 times, each 1 hour, filter, merging filtrate is concentrated into 1: 5 medicinal liquid.With 80 ℃ of medicinal liquid heating, add clarifier and stir, placed 2 hours; Add clarifier again and stir, place more than 5 hours, filter then; Filtrate is concentrated into thick paste, wears into 200 order fine powders after the drying; Add the Hirudo fine powder that has ground, stir evenly, it is an amount of to add water, general ball; Make 1000 grams.

Claims (10)

1, a kind of Chinese medicine preparation for the treatment of hysteromyoma is characterized in that, it contains following parts by weight of Chinese traditional medicine material: Semen Persicae 8-12, Rhizoma Curcumae 8-12, rhizoma sparganic 8-12, Hirudo 2-4, Pseudobulbus Cremastrae Seu Pleiones 8-12, Spica Prunellae 8-12, Olibanum 4-8, Myrrha 4-8.
2, the Chinese medicine preparation of treatment hysteromyoma according to claim 1 is characterized in that, wherein, the Chinese crude drug weight portion is: Semen Persicae 10, Rhizoma Curcumae 10, rhizoma sparganic 10, Hirudo 3, Pseudobulbus Cremastrae Seu Pleiones 10, Spica Prunellae 10, Olibanum 6, Myrrha 6.
3, a kind of Chinese medicine preparation for the treatment of hysteromyoma, it is characterized in that it contains following parts by weight of Chinese traditional medicine material: Semen Persicae 8-12, Rhizoma Curcumae 8-12, rhizoma sparganic 8-12, Hirudo 2-4, Pseudobulbus Cremastrae Seu Pleiones 8-12, Spica Prunellae 8-12, Olibanum 4-8, Myrrha 4-8, Carapax Trionycis 13-17, Radix Linderae 8-12, Herba Leonuri 8-12, Radix Bupleuri 6-10.
4, the Chinese medicine preparation of treatment hysteromyoma according to claim 3, it is characterized in that, wherein, the weight portion of Chinese crude drug is: Semen Persicae 10, Rhizoma Curcumae 10, rhizoma sparganic 10, Hirudo 3, Pseudobulbus Cremastrae Seu Pleiones 10, Spica Prunellae 10, Olibanum 6, Myrrha 6, Carapax Trionycis 15, the Radix Linderae 10, Herba Leonuri 10, Radix Bupleuri 8.
5, a kind of Chinese medicine preparation for the treatment of hysteromyoma, it is characterized in that, formed by following parts by weight of Chinese traditional medicine material: Semen Persicae 8-12, Rhizoma Curcumae 8-12, rhizoma sparganic 8-12, Hirudo 2-4, Pseudobulbus Cremastrae Seu Pleiones 8-12, Spica Prunellae 8-12, Olibanum 4-8, Myrrha 4-8, Carapax Trionycis 13-17, Radix Linderae 8-12, Herba Leonuri 8-12, Radix Bupleuri 6-10, Radix Astragali 13-17, Radix Angelicae Sinensis 6-10, Herba Cistanches 8-12.
6, the Chinese medicine preparation of treatment hysteromyoma according to claim 5, it is characterized in that, wherein, the weight portion of Chinese crude drug is: Semen Persicae 10, Rhizoma Curcumae 10, rhizoma sparganic 10, Hirudo 3, Pseudobulbus Cremastrae Seu Pleiones 10, Spica Prunellae 10, Olibanum 6, Myrrha 6, Carapax Trionycis 15, the Radix Linderae 10, Herba Leonuri 10, Radix Bupleuri 8, the Radix Astragali 15, Radix Angelicae Sinensis 8, Herba Cistanches 10.
7, a kind of preparation method for the treatment of the hysteromyoma Chinese medicine preparation is characterized in that, may further comprise the steps:
1) the weighting profit requires the weight portion of 1,2,3,4,5 or 6 described Chinese crude drugs respectively;
2) it is standby the Chinese crude drug Hirudo to be worn into fine powder separately;
3) with adding 8-12 times of water extraction 2-3 time after other Chinese crude drug mixing, each 1-2 hour, filter merging filtrate;
4) filtrate is concentrated into 1: the 4-6 medicinal liquid;
5) with 70 ℃-90 ℃ of medicinal liquid heating, add clarifier and stir, place;
6) add clarifier again and stir, place, filter;
7) filtrate is concentrated into thick paste, wears into fine powder after the drying;
8) add the Hirudo fine powder, stir evenly, make dosage form at last.
8, the preparation method of treatment hysteromyoma Chinese medicine preparation according to claim 7 is characterized in that, adds 10 times of water extraction 2 times, each 1 hour.
9, the preparation method of treatment hysteromyoma Chinese medicine preparation according to claim 7 is characterized in that, filtrate is concentrated into 1: 5 medicinal liquid.
10, the preparation method of treatment hysteromyoma Chinese medicine preparation according to claim 7 is characterized in that, its main constituent of described clarifier is the shell polymers.
CNB2006100961606A 2006-09-23 2006-09-23 Chinese-medicinal preparation for treating hysteromyoma and its making method Expired - Fee Related CN100531787C (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101129948B (en) * 2007-09-29 2010-06-09 陕西康惠制药股份有限公司 Pharmaceutical composition for treating gynecology hysteromyoma and processes for producing same
CN104096011A (en) * 2014-07-19 2014-10-15 吴修红 Medicine composition for treating hysteromyoma as well as preparation method and application thereof
CN104888157A (en) * 2015-07-06 2015-09-09 苗怡文 Traditional Chinese medicine preparation for treating hysteromyoma and preparation method thereof
CN108478750A (en) * 2018-05-28 2018-09-04 李冰 A kind of preparation method of the medicinal liquor for the treatment of tumor
CN109528985A (en) * 2019-01-28 2019-03-29 浴康中医保健养生(江苏)有限公司 It is a kind of for treating the Chinese materia medica preparation and preparation method of fibroid and lobular hyperplasia

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101129948B (en) * 2007-09-29 2010-06-09 陕西康惠制药股份有限公司 Pharmaceutical composition for treating gynecology hysteromyoma and processes for producing same
CN104096011A (en) * 2014-07-19 2014-10-15 吴修红 Medicine composition for treating hysteromyoma as well as preparation method and application thereof
CN104096011B (en) * 2014-07-19 2017-12-05 吴修红 A kind of pharmaceutical composition for treating fibroid and preparation method and application
CN104888157A (en) * 2015-07-06 2015-09-09 苗怡文 Traditional Chinese medicine preparation for treating hysteromyoma and preparation method thereof
CN108478750A (en) * 2018-05-28 2018-09-04 李冰 A kind of preparation method of the medicinal liquor for the treatment of tumor
CN109528985A (en) * 2019-01-28 2019-03-29 浴康中医保健养生(江苏)有限公司 It is a kind of for treating the Chinese materia medica preparation and preparation method of fibroid and lobular hyperplasia

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