CN1923154A - Blood vessel support bracket with little tissue prolapsus after implantation - Google Patents
Blood vessel support bracket with little tissue prolapsus after implantation Download PDFInfo
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- CN1923154A CN1923154A CNA2006100415344A CN200610041534A CN1923154A CN 1923154 A CN1923154 A CN 1923154A CN A2006100415344 A CNA2006100415344 A CN A2006100415344A CN 200610041534 A CN200610041534 A CN 200610041534A CN 1923154 A CN1923154 A CN 1923154A
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- waveform
- intravascular stent
- bracing ring
- serpentine
- support
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Abstract
The invention relates to a blood vessel support with less drop organism after being planted into organism, used to treat blood vessel block in puncture shaping surgery. Wherein, said support can be used in heart blood vessel, and outer blood vessels, via thin micro tube and laser to be carved into network structure; and the invention is formed by several groups of wave support rings (10) connected by connecting rods (20); each support ring (10) is formed by 2-5 groups of unit waves; nearby support rings (10) are connected by 2-10 connecting rods; the invention can avoid the support rod interfere the clamping and expanding, to improve flexibility, and the drug coat will not form web and the drug density will be uniform.
Description
Technical field
The present invention relates to a kind of expanding intravascular stent of puncture shaping surgery treatment angiemphraxis.This kind structure stand also is applicable to peripheral blood vessel (as the entocranial artery blood vessel etc.) except that being used for cardiovascular, belong to the technical field that medical apparatus and instruments is made.
Background technology
The intravascular stent art is that interventional therapy method is hindered by a kind of Wicresoft, this method is to utilize the foley's tube in PTA (the Percutaneous transluminal angioplasty) operation that intravascular stent is sent into the blood vessel place that narrows down, in balloon expandable, strut support, thereby reach the purpose of blood vessel dilating.Present most typical intravascular stent is to be formed through cut by the metal microtubule, and integral body is the net form tubular structure.During use, under the monitoring of medical imaging device, utilize medical apparatus and instruments such as puncture needle, conduit, this support is delivered to diseased region through tremulous pulse, support is expanded, strut the pathological changes tremulous pulse, reach the purpose of treatment.
Existing intravascular stent structure generally is that the different wave bracing ring utilizes the different connecting rods different mesh shape that is formed by connecting.Be connected with crest-crest, crest-trough, three kinds of main modes of trough-trough between the waveform bracing ring.China's utility model patent " coronary stent " (ZL00217528.2) all adopts the connected mode of crest-crest with " zero cripetura structure coronary artery expansion support " structure (ZL02219561.0), and its difference mainly is the connected mode difference.The shortcoming that crest-crest connects is that the diameter of the circle of contact within the grid window that forms is bigger, so easily formative tissue prolapsus behind the implantable intravascular, reduces the effective diameter that lumen of vessels obtains, and reduces therapeutic effect.
The connected mode of crest-trough is adopted in connection between the bracket leg support ring of the present invention, and this connected mode can be brought several benefits: the firstth, and the diameter of the circle of contact within the grid window that has reduced to form effectively reduces tissue prolapsus phenomenon; The secondth, blood vessel wall has been carried out the support of homogenization, the adherent property of support is better; The 3rd is that the connecting rod of crest-trough extends greatly than the axial effective length of the connecting rod of crest-crest, thereby has increased the axial compliance of intravascular stent, and the support compliance is good; The 4th is that the waveform that links to each other with the connecting rod flat segments is " ω " shape, the stress concentration in the time of can reducing the support dilatating and deformable, the fatigue life of improving support.
Still have 30～50% restenosis generation behind the successful percutaneous transluminal coronary angioplasty in 3～6 months, the generation of restenosis has become the noticeable research focus in Wicresoft interventional therapy cardiovascular disease field.Deepening continuously of the mechanism research that restenosis is taken place along with people finds that it is three main causes that cause restenosis that Wicresoft's interventional therapy causes smooth muscle cell proliferation, thrombosis and the blood vessel wall of vascular damaged initiation to reinvent.Keeping local high drug level and secular medicine controlled releasing is the main method of the preceding two kinds of reasons of treatment, and the implant frame art plays the support effect to injured blood vessel, can reduce the influence that blood vessel wall is reinvented, and becomes to solve the main method that blood vessel wall is reinvented.So people have produced implant frame naturally as pharmaceutical carrier, carry out the mode of topical and treat restenosis, and made coating stent of medicine (drug-eluting stents).
But existing coating stent of medicine adds the medicine coating on general bare bracket surface mostly, support Design does not take into full account the characteristics of its medicine carrying, therefore its structure has blood vessel wall drug level heterogeneity, has the too high and low excessively problem of local drug concentration of local drug concentration.Structural design of the present invention can be carried out the support of homogenization more effectively to blood vessel wall, the structure that this homogenization supports after coating medication coat also to be beneficial to drug release later at the uniform distribution of vascular wall tissue; And the reducing of tangential circle diameter within the grid window except reducing tissue prolapsus phenomenon, also can avoid within the grid window near the shortcoming of the drug level circle of contact center of circle, to overcome the deficiency of existing support.Because the serpentine structure of connecting rod has point-symmetric characteristics, make that also intravascular stent interference chance of bar when bending is little, simultaneously because interference can make this place's drug level too high.Adopting wave height not wait design in addition also is in order to reduce the interference of support bar when pressure is held.Above measure all can reduce the formation of carrying out " web " between the cradling piece of medication coat when preparing.
Summary of the invention
Technical problem: the object of the invention provides a kind of little intravascular stent of back tissue prolapsus of implanting, the intravascular stent of this structure is convenient to reduce the prolapsus that support is implanted the back tissue, interference when support is crooked is little and compliance is better, be beneficial to the generation of " web " between the bar when reducing bracket coating, and drug release homogeneous behind the support coating, overcome the deficiency that has the drug stent structure now.
Technical scheme: the present invention is achieved through the following technical solutions its purpose: this support reticulates structure by thin micro tube through laser engraving, and the material of described thin micro tube is any of 316L medical stainless steel, cochrome (MP35 or L605) or biodegradable (absorption) material.Described network structure is formed by connecting by connecting rod by some groups of waveform bracing rings, and every group of waveform bracing ring organized constituting of multiple unit ripple by 2-5, adopts 2～10 connecting rods to connect between the adjacent waveform bracing ring; The unit ripple has multiple structure, and connecting rod is that flat segments and bending section are formed.
Related content and variation further are explained as follows in the technique scheme:
1, described " tissue prolapsus little intravascular stent " is meant that connection between the bracket leg support ring adopts the connected mode of crest-trough, and the diameter of the circle of contact within the grid window that has reduced to form effectively reduces tissue prolapsus phenomenon; Blood vessel wall has been carried out the support of homogenization, and the adherent property of support is better; The connecting rod of crest-trough extends greatly than the axial effective length of the connecting rod of crest-crest, thereby has increased the axial compliance of intravascular stent, and the support compliance is good.
2, the waveform of the unit ripple that links to each other with the connecting rod flat segments is " ω " shape, the stress concentration in the time of can reducing the support dilatating and deformable, the fatigue life of improving support.
3, the structure that supports of homogenization after coating medication coat also to be beneficial to drug release later at the uniform distribution of vascular wall tissue; And the reducing of tangential circle diameter within the grid window except reducing tissue prolapsus phenomenon, also can avoid near the shortcoming of the drug level inscribed circle grid window incenter.
4, because the serpentine structure of connecting rod has point-symmetric characteristics, also make the interference of intravascular stent bar when bending reduce; The wave height difference of forming the unit ripple of waveform bracing ring has effectively been avoided being in support with connecting rod bending section serpentine and has been pressed interference when holding.Because interference can make this place's drug level too high.Avoid the design interfered can guarantee support formation of " web " when carrying out medication coat simultaneously.
5, in the technique scheme, described connecting rod bending section comprises following variation from structure: the position that bending section links to each other with crest can be in the optional position of crest circular arc, the shape respective change of serpentine, and accompanying drawing 1 is seen in several variations.Be used alternatingly serpentine and anti-serpentine when connecting between the waveform bracing ring, the distortion in the time of can avoiding the support expansion guarantees the concordance that support is expanded.
Beneficial effect: the technology of the present invention core and characteristics are: at reduce tissue prolapsus after support is implanted, avoid the interference of cradling piece when pressure is held and expand, increase compliance, medication coat do not form behind " web " and the support medicine carrying requirements such as drug level in blood vessel wall is evenly distributed, employing is in the waveform bracing ring connected mode of " crest-trough ", shape design that trough is connected to approximate " ω ", connecting rod is flat segments and bending section combination, and anti-interference design etc., guaranteed designing requirement and performance effectively, had a good application prospect.
Description of drawings
Fig. 1 for connecting rod bending section shape of the present invention and with crest junction point position view, wherein: Fig. 1 a is the serpentine bending section and depart from the crest summit and be connected, Fig. 1 b is that the serpentine bending section is connected with the crest summit, Fig. 1 c is anti-serpentine bending section and depart from the crest summit and be connected, and Fig. 1 d is that anti-serpentine bending section is connected with the crest summit;
Fig. 2 is the supporting structure periphery expanded view of the embodiment of the invention one;
Fig. 3 is the supporting structure periphery expanded view of the embodiment of the invention two;
Fig. 4 is the supporting structure periphery expanded view of the embodiment of the invention three;
Have in the above accompanying drawing: waveform bracing ring 10; Connecting rod 20; First module ripple 11; The second unit ripple 12; The 3rd unit ripple 13; The 4th unit ripple 14; Connect flat segments 21; Connect flat bending section 22; Trough junction point 31; Crest junction point 32.
The specific embodiment
Below in conjunction with drawings and Examples the present invention is further described:
Embodiment one: see shown in Figure 2ly, a kind of new structure intravascular stent, this support reticulate structure by 316L medical stainless steel thin micro tube through laser engraving and are constituted.Described network structure is formed by connecting by connecting rod 20 by 8 groups of bracing rings 10.The upside of bracing ring 10 alternately is made up of 3 first module ripples 11 and 3 second unit ripples 12; Downside alternately is made up of 3 the 3rd unit ripples 13 and 3 the 4th unit ripples 14.First module ripple 11 waveforms are " ω " shape, and the wave height of the 3rd unit ripple 13 is less than the wave height of the 4th unit ripple 14.The number of connecting rod 20 is 3 between the adjacent supports circle 10, and connecting rod 20 is formed by connecting by flat segments 21 and serpentine or anti-serpentine bending section 22, and crest junction point 32 is positioned at the inclined to one side 45 degree location points of crest circular arc; The area of all grid windows of support equates; Be used alternatingly serpentine and anti-serpentine connecting rod when connecting between the waveform bracing ring, the distortion in the time of can avoiding the support expansion guarantees the concordance that support is expanded.
Embodiment two: see shown in Figure 3ly, a kind of new structure intravascular stent, this support reticulate structure by cochrome L605 thin micro tube through laser engraving and are constituted.Described network structure is formed by connecting by connecting rod by 8 groups of bracing rings 10, and the upside of bracing ring 10 is that two groups of combined and alternativelies by 1 first module ripple 11 and 2 successive second unit ripples 12 constitute; The downside of bracing ring 10 is that two groups of combined and alternativelies by 1 the 1st unit ripple 11 and 2 the 3rd unit ripples 13 are formed.First module ripple 1 waveform is " ω " shape; The number of connecting rod 20 is 2 between the adjacent supports circle 10; Connecting rod 2 is formed by connecting by flat segments 21 and anti-serpentine bending section 22, and crest junction point 32 is positioned at crest extreme higher position point; The area of all grid windows of support equates.
Embodiment three: see shown in Figure 4ly, a kind of new structure intravascular stent, this support reticulate structure by cochrome L605 thin micro tube through laser engraving and are constituted.Described network structure is formed by connecting by connecting rod by 9 groups of bracing rings 10, and the upside of bracing ring 10 alternately is made up of 4 first module ripples 11 and 4 second unit ripples 12; Downside alternately is made up of 4 the 3rd unit ripples 13 and 4 the 4th unit ripples 14.First module ripple 11 waveforms are " ω " shape, and the 3rd unit ripple 13 wave height are less than the wave height of the 4th unit ripple 14.The number of connecting rod 20 is 4 between the adjacent supports circle 10, and each connecting rod 20 is formed by connecting by flat segments 21 and serpentine or anti-serpentine bending section 22, and crest junction point 32 is positioned at crest extreme higher position point; The area of all grid windows of support equates; Be used alternatingly serpentine and anti-serpentine connecting rod when connecting between the waveform bracing ring, the distortion in the time of can avoiding the support expansion guarantees the concordance that support is expanded.
Claims (7)
1, a kind of little intravascular stent of back tissue prolapsus of implanting, it is characterized in that: this intravascular stent is formed through laser engraving by thin micro tube, its structure is formed by connecting by connecting rod (20) by many groups waveform bracing ring (10), and every group of waveform bracing ring (10) is made of the various combination of 2 to 5 groups of first module ripples (11), the second unit ripple (12), the 3rd unit ripple (13), the 4th unit ripple (14); Adopt 2 to 10 connecting rods (20) to connect between the adjacent waveform bracing ring (10).
2, the little intravascular stent of back tissue prolapsus of implanting according to claim 1, it is characterized in that: the material of used thin micro tube is any of 316L medical stainless steel or cochrome or Biodegradable material.
3, the little intravascular stent of back tissue prolapsus of implanting according to claim 1 and 2, it is characterized in that: the first module ripple (11) of the waveform bracing ring (10) of formation is shaped as approximate " ω " shape.
4, the little intravascular stent of back tissue prolapsus of implanting according to claim 1 and 2, it is characterized in that: the connecting rod of described support (20) is formed by connecting by flat segments (21) and serpentine bending section (22).
5, the little intravascular stent of back tissue prolapsus of implanting according to claim 1 and 2 is characterized in that: the 3rd unit ripple (13) that constitutes waveform bracing ring (10) and the 4th unit ripple (14) be shaped as approximate " U " shape, the wave height difference of the two.
6, the little intravascular stent of back tissue prolapsus of implanting according to claim 1 and 2, it is characterized in that: the flat segments (21) of the connecting rod of described support (20) is connected to trough junction point (31) with the first module ripple (11) of waveform bracing ring (10); The 3rd unit ripple (13) of the serpentine bending section (22) of connecting rod (20) and waveform bracing ring (10) or the 4th unit ripple (14) be connected to crest junction point (32), crest junction point (32) can be near crest the optional position of circular arc.
7, the little intravascular stent of back tissue prolapsus of implanting according to claim 1 and 2, it is characterized in that: the shape of the serpentine bending section (22) of the connecting rod of described support (20) adjusts with the change in location of crest junction point (32); Be positive serpentine or anti-serpentine; Its shape can be constant when connecting waveform bracing ring (10), perhaps positive serpentine and anti-serpentine is used alternatingly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100415344A CN1923154A (en) | 2006-09-13 | 2006-09-13 | Blood vessel support bracket with little tissue prolapsus after implantation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100415344A CN1923154A (en) | 2006-09-13 | 2006-09-13 | Blood vessel support bracket with little tissue prolapsus after implantation |
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| Publication Number | Publication Date |
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| CN1923154A true CN1923154A (en) | 2007-03-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2006100415344A Pending CN1923154A (en) | 2006-09-13 | 2006-09-13 | Blood vessel support bracket with little tissue prolapsus after implantation |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101883592A (en) * | 2007-10-10 | 2010-11-10 | Miv治疗有限公司 | Calcium phosphate coated stents comprising cobalt chromium alloy |
| CN101516296B (en) * | 2006-09-29 | 2012-03-28 | 泰尔茂株式会社 | Stent and stent delivery device |
| CN102448406A (en) * | 2009-09-30 | 2012-05-09 | 泰尔茂株式会社 | Stent |
| CN106236342A (en) * | 2016-08-23 | 2016-12-21 | 深圳市信立泰生物医疗工程有限公司 | A kind of implanted complete biological absorbable blood vessel polymer support |
| CN106667630A (en) * | 2012-05-14 | 2017-05-17 | C·R·巴德公司 | Uniformly expandable stent |
| CN107569299A (en) * | 2017-09-04 | 2018-01-12 | 上海脉全医疗器械有限公司 | A kind of bioabsorbable stent |
| CN111529152A (en) * | 2020-05-15 | 2020-08-14 | 上海君联医疗设备有限公司 | Blood vessel support |
| CN112656543A (en) * | 2020-12-18 | 2021-04-16 | 王潇 | Peripheral vascular stent with reduced migration capability |
-
2006
- 2006-09-13 CN CNA2006100415344A patent/CN1923154A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101516296B (en) * | 2006-09-29 | 2012-03-28 | 泰尔茂株式会社 | Stent and stent delivery device |
| CN101883592A (en) * | 2007-10-10 | 2010-11-10 | Miv治疗有限公司 | Calcium phosphate coated stents comprising cobalt chromium alloy |
| CN102448406A (en) * | 2009-09-30 | 2012-05-09 | 泰尔茂株式会社 | Stent |
| CN102448406B (en) * | 2009-09-30 | 2014-08-27 | 泰尔茂株式会社 | Stent |
| CN106667630A (en) * | 2012-05-14 | 2017-05-17 | C·R·巴德公司 | Uniformly expandable stent |
| CN106236342A (en) * | 2016-08-23 | 2016-12-21 | 深圳市信立泰生物医疗工程有限公司 | A kind of implanted complete biological absorbable blood vessel polymer support |
| CN106236342B (en) * | 2016-08-23 | 2024-04-30 | 深圳信立泰医疗器械股份有限公司 | Implantable complete biological absorbable vascular polymer stent |
| CN107569299A (en) * | 2017-09-04 | 2018-01-12 | 上海脉全医疗器械有限公司 | A kind of bioabsorbable stent |
| CN111529152A (en) * | 2020-05-15 | 2020-08-14 | 上海君联医疗设备有限公司 | Blood vessel support |
| CN112656543A (en) * | 2020-12-18 | 2021-04-16 | 王潇 | Peripheral vascular stent with reduced migration capability |
| CN112656543B (en) * | 2020-12-18 | 2024-05-07 | 王潇 | Peripheral vascular stent with reduced migration capacity |
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