CN1922322A - 使用具有降低活性的AsuR调节物的重组棒状细菌生产L－氨基酸的方法 - Google Patents

使用具有降低活性的AsuR调节物的重组棒状细菌生产L－氨基酸的方法 Download PDF

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Publication number
CN1922322A
CN1922322A CNA2005800057916A CN200580005791A CN1922322A CN 1922322 A CN1922322 A CN 1922322A CN A2005800057916 A CNA2005800057916 A CN A2005800057916A CN 200580005791 A CN200580005791 A CN 200580005791A CN 1922322 A CN1922322 A CN 1922322A
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CN
China
Prior art keywords
gene
enzyme
methionine
asur
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800057916A
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English (en)
Chinese (zh)
Inventor
丹尼尔·科赫
克里斯蒂安·吕克特
约恩·卡利诺夫斯基
阿尔弗雷德·普赫勒
布丽吉特·巴瑟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH filed Critical Degussa GmbH
Publication of CN1922322A publication Critical patent/CN1922322A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CNA2005800057916A 2004-02-27 2005-01-13 使用具有降低活性的AsuR调节物的重组棒状细菌生产L－氨基酸的方法 Pending CN1922322A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200410009453 DE102004009453A1 (de) 2004-02-27 2004-02-27 Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von coryneformen Bakterien
DE102004009453.5 2004-02-27

Publications (1)

Publication Number Publication Date
CN1922322A true CN1922322A (zh) 2007-02-28

Family

ID=34853738

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800057916A Pending CN1922322A (zh) 2004-02-27 2005-01-13 使用具有降低活性的AsuR调节物的重组棒状细菌生产L－氨基酸的方法

Country Status (4)

Country Link
EP (1) EP1756279A1 (fr)
CN (1) CN1922322A (fr)
DE (1) DE102004009453A1 (fr)
WO (1) WO2005083082A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109890972A (zh) * 2016-10-26 2019-06-14 味之素株式会社 生产目标物质的方法
CN116731950A (zh) * 2023-08-10 2023-09-12 中国科学院天津工业生物技术研究所 谷氨酸棒杆菌抗逆工程菌及其在生产酸性生物基化学品中应用

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2447146C2 (ru) * 2005-07-18 2012-04-10 Эвоник Дегусса Гмбх Рекомбинантные микроорганизмы, продуцирующие метионин
CN101164694A (zh) 2006-10-20 2008-04-23 德古萨股份公司 用于催化气相氧化的混合氧化物催化剂
DE102006054202A1 (de) * 2006-11-17 2008-05-21 Evonik Degussa Gmbh Allele des oxyR-Gens aus coryneformen Bakterien
WO2008101850A1 (fr) * 2007-02-19 2008-08-28 Evonik Degussa Gmbh Procédé de production de méthionine dans des corynebactéries par la surexpression d'enzymes de la voie pentose phosphate
KR101756338B1 (ko) 2016-01-15 2017-07-10 고려대학교 산학협력단 L-시스테인 생산용 변이미생물 및 이를 이용한 l-시스테인의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
DE10126164A1 (de) * 2001-05-30 2002-12-05 Degussa Für das metD-gen kodierende Nukleotidsequenzen
DE10128510A1 (de) * 2001-06-13 2002-12-19 Degussa Methode zur Fermentationskontrolle

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109890972A (zh) * 2016-10-26 2019-06-14 味之素株式会社 生产目标物质的方法
CN109890972B (zh) * 2016-10-26 2022-11-08 味之素株式会社 生产目标物质的方法
CN116731950A (zh) * 2023-08-10 2023-09-12 中国科学院天津工业生物技术研究所 谷氨酸棒杆菌抗逆工程菌及其在生产酸性生物基化学品中应用

Also Published As

Publication number Publication date
DE102004009453A1 (de) 2005-09-15
WO2005083082A1 (fr) 2005-09-09
EP1756279A1 (fr) 2007-02-28

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