CN1907274A - Pharmaceutical preparation such as hemsleyadine dispersable tablet et al. and preparation method thereof - Google Patents
Pharmaceutical preparation such as hemsleyadine dispersable tablet et al. and preparation method thereof Download PDFInfo
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- CN1907274A CN1907274A CN 200510088657 CN200510088657A CN1907274A CN 1907274 A CN1907274 A CN 1907274A CN 200510088657 CN200510088657 CN 200510088657 CN 200510088657 A CN200510088657 A CN 200510088657A CN 1907274 A CN1907274 A CN 1907274A
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- hemsleyadin
- preparation
- tablet
- dispersible tablet
- dispersible
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Abstract
Disclosed is a medicinal preparation such as hemsleyadine dispersible tablet and its preparing process, which comprises step of mixing hemsleyadine with right amount of auxiliary materials.
Description
Technical field
The processing technology technical field that this present invention relates to pharmaceutical preparation relates in particular to the preparation method of dosage forms such as hemsleyadin dispersible tablet, enteric coatel tablets, enteric coated capsule, effervescent tablet, granule, pill, pellet.
Background technology
Dispersible tablet is meant in water the homodisperse tablet of disintegrate rapidly, and dispersible tablets of Chinese medicine is exactly to be raw material with Chinese medicine extract, the former powder of Chinese medicine or refining intermediate, adds what proper auxiliary materials was made, can be in water the homodisperse tablet of disintegrate rapidly.Dispersible tablet is the novel form of just developing in recent years.It is fast that dispersible tablets of Chinese medicine has a disintegrate, stripping, absorption, the bioavailability height, and taking convenience, preparation technology is simple, working condition is not had advantages such as specific (special) requirements.The production certification of the domestic dispersible tablet of approved so far is about 270 at present, but wherein has only 7 of three herbal species to produce certification (Herb Gynostemmae Pentaphylli total glycosides dispersible tablet: the accurate word Z20000091 of traditional Chinese medicines; Xuesaitong dispersible tablet: the accurate word Z20040128 of traditional Chinese medicines, Z20050024, Z20060142, Z20050014; The Semen Ginkgo dispersible tablet: the accurate word Z20050178 of traditional Chinese medicines, Z20050234).The dispersible tablets of Chinese medicine of bibliographical information has Herb Gynostemmae Pentaphylli total glycosides dispersible tablet, gold zone dispersible tablet, Radix Scutellariae lung heat clearing dispersible tablet, Daidzein dispersible tablet at present; Cold drug dispersible tablet and Moschus are protected heart dispersible tablet.
Dispersible tablet is a kind of pharmaceutical formulation commonly used, according to China's medicine registration management way, changes dosage form and belongs to the 8th kind new medicine, and original dosage form of hemsleyadin dispersible tablet is: hemsleyadine tablet.Hemsleyadine tablet has been listed in the 19 of the Drug Standard of Ministry of Public Health of the Peoples Republic of China " Chinese traditional patent formulation preparation ".Tablets, easy to carry, but to the time that the low age child is difficult for swallowing, the disintegrate needs are long, affect the treatment.We use the modern pharmaceutical technology former tablet technology are done necessary improvement, make new preparation---dispersible tablet.
Summary of the invention
The purpose of this invention is to provide pharmaceutical preparatioies such as a kind of hemsleyadin dispersible tablet and preparation method thereof,, satisfy the clinical treatment needs better to improve the quality of products and to make things convenient for child patient to take.
The invention provides following technical scheme:
One, the optimum formula of hemsleyadin dispersible tablet is formed
Hemsleyadin 2-10g right amount of auxiliary materials is made 1000 altogether.
Two, hemsleyadin dispersible tablet preparation technology
Hemsleyadin 2g adds the proper auxiliary materials mixing, makes dispersible tablet or other oral formulations.
The present invention and original its superiority of technology comparison are: hemsleyadin dispersible tablet of the present invention can add after the aqueous dispersion oral, also dispersible tablet can be contained in to suck clothes in the mouth or swallow, thereby take very conveniently, is particularly suitable for old, the children and the patient of difficulty that swallows.When taking with the solution form, drug effect is rapid, the bioavailability height; Volume, weight are little, carry more conveniently, and logistics cost is low.
The specific embodiment
The hemsleyadin dispersible tablet
The optimum implementation of hemsleyadin dispersible tablet is: hemsleyadin 5g, polyvinylpyrrolidone 9g, mannitol 226g, carboxymethylstach sodium 30g, microcrystalline Cellulose 30g.Mixing is pulverized, and granulates, and is pressed into dispersible tablet, check, packing.
Claims (3)
1. pharmaceutical preparatioies such as hemsleyadin dispersible tablet and preparation method thereof is characterized in that hemsleyadin and proper auxiliary materials mixing are made dispersible tablet or other medicines preparation.
2. pharmaceutical preparatioies such as hemsleyadin dispersible tablet according to claim 1 and preparation method thereof, it is characterized in that, one or more adjuvant of hemsleyadin and cross-linking sodium carboxymethyl cellulose, carboxymethylstach sodium, low-substituted hydroxypropyl cellulose, crosslinked plain vinylpyrrolidone, microcrystalline Cellulose, micropowder silica gel, mannitol, pregelatinized starch etc. is mixed, make and disperse to divide.
3. pharmaceutical preparatioies such as hemsleyadin dispersible tablet according to claim 1 and preparation method thereof, it is characterized in that, hemsleyadin with after one or more proper auxiliary materials is mixed, is made dosage forms such as enteric coatel tablets, enteric coated capsule, effervescent tablet, chewable tablet, buccal tablet, oral cavity disintegration tablet, granule, pill, pellet, drop pill, soft capsule, powder, mixture, oral liquid, syrup, tincture, gel, ointment, membrane, injection respectively by the preparation technology of each dosage form.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510088657 CN1907274A (en) | 2005-08-01 | 2005-08-01 | Pharmaceutical preparation such as hemsleyadine dispersable tablet et al. and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510088657 CN1907274A (en) | 2005-08-01 | 2005-08-01 | Pharmaceutical preparation such as hemsleyadine dispersable tablet et al. and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1907274A true CN1907274A (en) | 2007-02-07 |
Family
ID=37698612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510088657 Pending CN1907274A (en) | 2005-08-01 | 2005-08-01 | Pharmaceutical preparation such as hemsleyadine dispersable tablet et al. and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1907274A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101829121B (en) * | 2007-02-13 | 2011-06-22 | 昆明四创药业有限公司 | Hemsleyadin sustained-release preparation |
| CN101780094B (en) * | 2007-02-13 | 2011-08-17 | 昆明四创药业有限公司 | Slow-release preparation of cucurbitacin |
-
2005
- 2005-08-01 CN CN 200510088657 patent/CN1907274A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101829121B (en) * | 2007-02-13 | 2011-06-22 | 昆明四创药业有限公司 | Hemsleyadin sustained-release preparation |
| CN101780094B (en) * | 2007-02-13 | 2011-08-17 | 昆明四创药业有限公司 | Slow-release preparation of cucurbitacin |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |