CN1895607A - Extraction and its use for garlicin and garlic active component composition - Google Patents
Extraction and its use for garlicin and garlic active component composition Download PDFInfo
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- CN1895607A CN1895607A CN 200510083019 CN200510083019A CN1895607A CN 1895607 A CN1895607 A CN 1895607A CN 200510083019 CN200510083019 CN 200510083019 CN 200510083019 A CN200510083019 A CN 200510083019A CN 1895607 A CN1895607 A CN 1895607A
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Abstract
A process for extracting the composition of garlic glycoside and bioactive components of garlic, which is used for protecting skin, beautifying face, taking care of health and preparing medicine, includes such steps as mashing garlic cloves, oxidizing in air, and enzymolyzing.
Description
Technical field
The present invention relates to a kind of compositions that contains allin and garlic biological activity component, particularly a kind of extraction process and this biological product with biological product are used for beauty and skin care, health care, sport nutrition, medical treatment and cure the disease.
Background technology
Show according to scientific research, there is kind more than 100 that the effective ingredient of health care and medical value is arranged in the Bulbus Allii head, prior art is extracted the Bulbus Allii quintessence oil in the Bulbus Allii head more, and the Bulbus Allii quintessence oil is a liposoluble substance, account for the 0.2%-0.3% of Bulbus Allii head, accounting for 20%-25% water soluble ingredient and bioactive ingredients like this in the Bulbus Allii can't be fully utilized, prior art also handlebar uncooked garlic head directly is developed into lyophilized powder under low temperature state, this technology has been ignored a process, be that Bulbus Allii head takes 10 day time and allinase decomposed alliin produce multiple effective active components gradually voluntarily after room temperature is smashed to pieces, do not have through this process, the effective active ingredient substance of Bulbus Allii can't produce and then can't realize extracting and utilize, and original allicin does not have separatedly to fall, this is with directly edible uncooked garlic head situation is the same, and allicin can bring the zest effect to gastrointestinal mucosa and eyes.Prior art also has to be extracted Bulbus Allii head interior edema soluble components garlicin and makes medicinal products, its objective is that utilizing garlicin in the Bulbus Allii head is that the effective ingredient of diallyl two mercaptan compounds is used for killing the virus and the usefulness of antiinflammatory, this application number that I apply for calendar year 2001 be in 01127010.1 patent document and the paper of Fujian Province Science and Technology Association " introduce and seek advice from " 2004 6 phases of academic journals of being responsible for " natural garlicin solvent kill the virus effect detection and assessment " in argumentation is all arranged.The permanent loose board " garlicin enteric coated capsule " that China imperial Pharmaceutical of Hubei gold Co., Ltd of and for example selling on the market produces is exactly an example.
Present domestic patent retrieval finds out that extracting has the water miscible allin of medical value and the compositions of garlic biological activity component still not to be reported from Bulbus Allii head.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art part, provide a kind of and utilize allinase to decompose alliin through the abundant oxidation of air from Bulbus Allii juice, to extract the biological product that do not contain a large amount of garlicin compositions stable in properties, water miscible, extraction ratio 15%～20% again under the room temperature state Bulbus Allii head being smashed to pieces: the compositions of allin and garlic biological activity component.
The present invention be more particularly directed to above-mentioned composition and can be used as the allin that beauty and skin care, health care, sport nutrition, medical treatment cure the disease and the compositions of garlic biological activity component.
According to the present invention, including allin component (A) and garlic biological activity component in above-mentioned allin and the garlic biological activity component compound is that component (B) also has component (C)
Allin component (A) is:
Garlic biological activity component component (B) is:
(a) S-acrylic cystine
(b) S-methyl cystine
(c) prostate A
(d) alduronic acid
(e) nicotiamide
(f) sarcosine
(g) trace element-selenium, germanium
Component (C) is bound water (H
2O)
Component (A) accounts for 65%～85% of component (A) and component (B) and component (C) total content
Component (B) accounts for 10～15% of component (A) and component (B) and component (C) total content
Component (C) accounts for 3～12% of component (A) and component (B) and component (C) total content
Biological product of the present invention can adopt following extraction process:
(1) selects fresh uncooked garlic head;
(2) remove the peel, sieve and remove earth, sand and other foreign material, under 20 ℃～37 ℃ of room temperature, smash into mashed garlic to pieces;
(3) mashed garlic is packed in the hermetic container that can seal, charge weight is 2/3rds of a container capacity;
(4) 95% ethanol is added in this container, be as the criterion with the mashed garlic that floods in the container;
(5) ethanol and mashed garlic are fully stirred, mix homogeneously, with container add a cover seal with ethanol outwards the volatilization be as the criterion;
(6) under 20 ℃～37 ℃ room temperature conditions, left standstill ten days;
(7) with the ethanol behind the abundant oxidation enzymolysis, mashed garlic mixture squeeze and filter, remove slag;
(8) filtrate is placed in the vacuum film concentrator, heat to filtrate that evacuation concentrates to 60 ℃ the condition, finish, reclaim the ethanol of extracting out with condensation method until ethanol and filtrate separation;
(9) filtrate is put into the water dumping centrifuge that per minute 3000～5000 changes under 20 ℃～37 ℃ of room temperature, centrifuge dripping 30 minutes is removed isolated liquid, takes out gluey seminal fluid and is biological product: the compositions of allin and garlic biological activity component.
The present invention be from food uncooked garlic head through smashing abundant oxidation to pieces after allinase decomposes the chemical compound that alliin produces is allin and garlic biological activity component compound, these compositions stable in properties, human body is had no side effect, nonirritant, the extraction ratio height has the biological product of effectively medicinal and health care.
The following stated embodiment describes the present invention in detail.
Main in these embodiments effect all results from this compositions.
Embodiment 1
(1) selects fresh uncooked garlic head;
(2) remove the peel, sieve and remove earth, sand and other foreign material, under 20 ℃～37 ℃ of room temperature, smash into mashed garlic to pieces;
(3) mashed garlic is packed in the hermetic container that can seal, charge weight is 2/3rds of a container capacity;
(4) 95% ethanol is added in this container, be as the criterion with the mashed garlic that floods in the container;
(5) ethanol and mashed garlic are fully stirred, mix homogeneously, with container add a cover seal with ethanol outwards the volatilization be as the criterion;
(6) under 20 ℃～37 ℃ room temperature conditions, left standstill ten days;
(7) with the ethanol behind the abundant oxidation enzymolysis, mashed garlic mixture squeeze and filter, remove slag;
(8) filtrate is placed in the vacuum film concentrator, heat to filtrate that evacuation concentrates to 60 ℃ the condition, finish, reclaim the ethanol of extracting out with condensation method until ethanol and filtrate separation;
(9) filtrate is put into the water dumping centrifuge that per minute 3000～5000 changes under 20 ℃～37 ℃ of room temperature, centrifuge dripping 30 minutes is removed isolated liquid, takes out gluey seminal fluid and is biological product: the compositions of allin and garlic biological activity component.
Embodiment 2
The product of embodiment 1 is added fresh Sucus Cucumidis sativi, stir, can be mixed with cosmetology reduce wrinkle facial film in product and 10: 3 ratio of Sucus Cucumidis sativi.
Embodiment 3
Embodiment 1 products obtained therefrom is added living Sucus Chaenomelis, stir with giving birth to 10: 2 ratio of Sucus Chaenomelis, can obtain skin protection acne removing antiinflammatory beauty cream in product.
Embodiment 4
Embodiment 1 products obtained therefrom directly is prepared into soft capsule, can be as the health-caring capsule that prevents cardiovascular and cerebrovascular disease and prevention of prostatic hyperplasia, blood pressure lowering.
Embodiment 5
Embodiment 1 products obtained therefrom is mixed with motion shape supplementary in 3: 2: 5 ratio and glucose and sterilized water.Allaying tiredness prevents the accumulation of lactic acid in the body rapidly, strengthens physical ability, regains one's strength.
Claims (10)
1, a kind of biological product is characterized in that, contain the compositions of allin and garlic biological activity component.
2, biological product according to claim 1, it is characterized in that, the allin chemical molecular is that the end of three amino acid whose tripeptides of connection and the sulfenyl of acrylic combine, the nitrogen-atoms of head and 2 sugared glucosides in half hole that condensation forms in conjunction with formation, and content is 65～85%.
3, biological product according to claim 2 is characterized in that, also contain biological activity: S-acrylic cystine, S-methyl cystine, prostate A, alduronic acid, nicotiamide, sarcosine and trace element-selenium and germanium, content is 10～15%.
4, biological product according to claim 1 is characterized in that, also contain bound water 3%～12%.
5, biological product according to claim 1 is characterized in that, are the xanchromatic water miscible gluey mucus of a kind of palm fibre.
6, a kind of extraction process of biological product is characterized in that:
(1) selects fresh uncooked garlic head;
(2) remove the peel, sieve and remove earth, sand and other foreign material, under 20 ℃～37 ℃ of room temperature, smash into mashed garlic to pieces;
(3) mashed garlic is packed in the hermetic container that can seal, charge weight is 2/3rds of a container capacity;
(4) 95% ethanol is added in this container, be as the criterion with the mashed garlic that floods in the container;
(5) ethanol and mashed garlic are fully mixed; Container added a cover seals, with ethanol outwards volatilization be as the criterion;
(6) under 20 ℃～37 ℃ room temperature conditions, left standstill ten days;
(7) with the ethanol behind the abundant oxidation enzymolysis, mashed garlic pulp mixture squeeze and filter, remove slag;
(8) filtrate is placed in the vacuum film concentrator, heat to filtrate that evacuation concentrates to 60 ℃ the condition, finish, use the condensation method recovered alcohol until ethanol and filtrate separation;
(9) filtrate that will concentrate is put into the water dumping centrifuge that per minute 3000～5000 changes under 20 ℃～37 ℃ of room temperature, centrifuge dripping 30 minutes, remove isolated liquid, take out gluey seminal fluid and be biological product---the compositions of allin and garlic biological activity component.
7, a kind of biological product is characterized in that, can be used as beauty and skin care, acne removing antiinflammatory.
8, a kind of biological product is characterized in that, can be used for health care, anti-ageing diseases prevention, prevention prostate hyperplasia, hypertrophy.
9, a kind of biological product is characterized in that, can be used for sport nutrition, makeup energy, prevention fatigue, recover the strong muscle power of physical ability.
10, a kind of biological product is characterized in that, can be used for preventing and treating cardiovascular and cerebrovascular disease, blood circulation promoting and blood stasis dispelling, mediation blood capillary, blood pressure lowering.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510083019 CN1895607A (en) | 2005-07-12 | 2005-07-12 | Extraction and its use for garlicin and garlic active component composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510083019 CN1895607A (en) | 2005-07-12 | 2005-07-12 | Extraction and its use for garlicin and garlic active component composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1895607A true CN1895607A (en) | 2007-01-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 200510083019 Pending CN1895607A (en) | 2005-07-12 | 2005-07-12 | Extraction and its use for garlicin and garlic active component composition |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102382020A (en) * | 2010-08-31 | 2012-03-21 | 成都菊乐制药有限公司 | Method for simultaneously extracting alliin and garlic enzyme from garlic |
| CN105385716A (en) * | 2015-10-12 | 2016-03-09 | 江苏师范大学 | Method for separating sulfur-containing compounds in garlic by adopting counter-current chromatography |
| WO2016199885A1 (en) * | 2015-06-12 | 2016-12-15 | 湧永製薬株式会社 | Blood pressure-lowering agent |
| CN107260650A (en) * | 2017-07-24 | 2017-10-20 | 丘利锦 | A kind of preparation method of garlic honey facial mask |
| CN111494283A (en) * | 2020-05-30 | 2020-08-07 | 欧露莲生物科技(广东)有限公司 | Garlic extract composition skin care product containing garlic peptide and preparation process thereof |
| JPWO2019031442A1 (en) * | 2017-08-07 | 2020-08-20 | 湧永製薬株式会社 | Blood flow improver |
-
2005
- 2005-07-12 CN CN 200510083019 patent/CN1895607A/en active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102382020A (en) * | 2010-08-31 | 2012-03-21 | 成都菊乐制药有限公司 | Method for simultaneously extracting alliin and garlic enzyme from garlic |
| AU2016275642C1 (en) * | 2015-06-12 | 2020-09-17 | Wakunaga Pharmaceutical Co., Ltd. | Antihypertensive agent |
| WO2016199885A1 (en) * | 2015-06-12 | 2016-12-15 | 湧永製薬株式会社 | Blood pressure-lowering agent |
| JPWO2016199885A1 (en) * | 2015-06-12 | 2018-03-29 | 湧永製薬株式会社 | Antihypertensive |
| US10363234B2 (en) | 2015-06-12 | 2019-07-30 | Wakunaga Pharmaceutical Co., Ltd. | Antihypertensive agent |
| AU2016275642B2 (en) * | 2015-06-12 | 2020-04-30 | Wakunaga Pharmaceutical Co., Ltd. | Antihypertensive agent |
| CN105385716A (en) * | 2015-10-12 | 2016-03-09 | 江苏师范大学 | Method for separating sulfur-containing compounds in garlic by adopting counter-current chromatography |
| CN105385716B (en) * | 2015-10-12 | 2018-05-25 | 江苏师范大学 | A kind of method that sulfur-containing compound in garlic is separated using countercurrent chromatography |
| CN107260650A (en) * | 2017-07-24 | 2017-10-20 | 丘利锦 | A kind of preparation method of garlic honey facial mask |
| JPWO2019031442A1 (en) * | 2017-08-07 | 2020-08-20 | 湧永製薬株式会社 | Blood flow improver |
| JP7146768B2 (en) | 2017-08-07 | 2022-10-04 | 湧永製薬株式会社 | Blood flow improver |
| CN111494283A (en) * | 2020-05-30 | 2020-08-07 | 欧露莲生物科技(广东)有限公司 | Garlic extract composition skin care product containing garlic peptide and preparation process thereof |
| CN111494283B (en) * | 2020-05-30 | 2020-12-25 | 欧露莲生物科技(广东)有限公司 | Garlic extract composition skin care product containing garlic peptide and preparation process thereof |
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Open date: 20070117 |