CN1895429A - Externally-applied Chinese-medicinal abstergent for treating gynecological inflammation - Google Patents
Externally-applied Chinese-medicinal abstergent for treating gynecological inflammation Download PDFInfo
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- CN1895429A CN1895429A CN 200610042954 CN200610042954A CN1895429A CN 1895429 A CN1895429 A CN 1895429A CN 200610042954 CN200610042954 CN 200610042954 CN 200610042954 A CN200610042954 A CN 200610042954A CN 1895429 A CN1895429 A CN 1895429A
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Abstract
A Chinese medicine in the form of exterior-applied lotion for treating and preventing the gynechologic inflammations is prepared from 11 Chinese-medicinal materials including flavescent sophora root, coptis root, astragalus root, fleece flower root, etc.
Description
Technical field
The present invention relates to the gynopathic Chinese patent medicine of a kind of treatment, especially relate to a kind of Chinese medicine external-use lotion for the treatment of gynecological inflammation and preparation method thereof.
Background technology
Women's damp-heat vaginal discharge disease is a commonly encountered disease, shows that according to investigations vulvitis, colpitic sickness rate are about 59.7%; Sickness rate that at present should disease rises year by year, and age of onset has trend in advance, and the characteristics that this type of disease is multiple, relapse rate is high have seriously influenced numerous women's physical and mental health, though it is many to treat this sick medicine in the market, and unsatisfactory curative effect.
Summary of the invention
The object of the invention provides a kind of good effect, has no side effect, and is easy to use, and energy is the Chinese medicine external-use lotion of the treatment gynecological inflammation of relief of symptoms fast, to overcome the deficiency of existing medicine.
The present invention is achieved in that it is by 108～132 parts of Radix Sophorae Flavescentiss, 72～88 parts of Rhizoma Coptidis, 108～132 parts of Cortex Phellodendris, 36～44 parts in Pericarpium Zanthoxyli, 108～132 parts of Fructus Cnidiis, 108～132 parts of the Radixs Astragali, 108～132 parts of Radix Polygoni Multiflori, 108～132 parts of the Fructus Kochiae, 108～132 parts of Folium Isatidiss, 108～132 parts of Radix Paeoniae Rubra, Radix Angelicae Sinensis decocts with water 2～3 times for 108～132 parts, each 1～2 hour, each time decoction liquor is merged filtration, get filtrate, when filtrate is concentrated into 40～60 ℃ of temperature, its relative density is 1.20～1.25 clear paste, add ethanol, make to contain alcohol amount and reach 60～80%, left standstill 43～52 hours, filter, reclaim ethanol, add distilled water to regulation, add 3～5 parts of sodium laurylsulfates again, 1～3 part in benzoic acid, left standstill 21～26 hours, filter, embedding promptly gets product.
Owing to adopted technique scheme, the present invention and existing treatment damp heat downward flowing type pruritus vulvae, vulval eczema, the medicine of gynaecopathias such as vaginitis is compared, and it is raw material that the present invention adopts genuine Chinese crude drug, reasonable recipe, determined curative effect and having no side effect.
Radix Sophorae Flavescentis is the dry root of leguminous plant Radix Sophorae Flavescentis Sophora flavescens Ait. in the present invention's prescription, contain matrine (matrine), oxymatrine (oxymatrine), sophoranole (sophoranole), N-Methylcytisine (N-methylcytisine), Anagyrine (anagyrine), baptifoline (baptifoline), dehydrogenation matrine (sophocarpine), d-Iosmatrine (d-isomatrine), kuraridin 2,2',4,4'-Tetrahydroxy-6'-methoxy-3'-(5-methyl-2-isopropenylhex-4-enyl)chalcone (kuraridin), nor-kurarinone (norkurarinone), Radix Sophorae Flavescentis heavy stone used as an anchor alcohol (kuraridinol), Radix Sophorae Flavescentis alcohol (kurarinol), neokurarinol (neo-kurarinol), nor-Radix Sophorae Flavescentis alcohol (norkurarinol), isokurarinone, other contains awns third xanthin (formononetin).Be mainly used in heat clearing and damp drying, parasite killing, diuresis.Be used for hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.Rhizoma Coptidis is a cohosh Rhizoma Coptidis Coptis chinensis Franch. rhizome, contains berberine (berberine), coptisine (coptisine), palmatine (palmatine), jateorhizine (jatrorrhizine), magnoline (magnoflorine) etc.Be mainly used in heat clearing and damp drying, the removing water retention by purgation detoxifcation.Be used for damp and hot feeling of fullness, vomiting, dysentery, jaundice, unconsciousness due to high fever, dysphoria and insomnia, heat in blood and tell nosebleed, toothache, carbuncle furuncle.Cortex Phellodendri is the bark of rutaceae Cortex Phellodendri Phellodendron amurense Rupr., the main berberine that contains, and contain palmatine (palmatine), jateorhizine (jatrorrhizine), phellodendrine (phellodendrine), Caulis menispermi and appoint alkali (menisperine), candicine (candicine), obacunone (obacunone) etc. to be mainly used in heat clearing and damp drying, pathogenic fire purging removes steams, and skin ulcer is treated in detoxifcation.Be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin.Fructus Cnidii is the fruit of samphire cnidium monnieri Cnidium monnieri (L.) Cuss., contains pinene, isovaleric acid borneol acetate (bornyl isovalerate) osthole (osthol), Columbianetin (+)-Columbianetin., bergapton (bergapten), osthole (cnidiadin), isopimpinellin (isopimpinellin) etc.Be used for warming the kidney to invigorate YANG, dampness is dispeled the wind, parasite killing.Be used for sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.Pericarpium Zanthoxyli is rutaceae Pericarpium Zanthoxyli Zanthoxylum bungeanumMaxim..The Radix Astragali is the root of leguminous plant Radix Astagali Astragalus membranaceus Bge.var.mongholicus (Bge.) Hsiao, contain flavonoid composition calycosin (calycosin), 3-hydroxyl-9,10-dimethoxy Lignum pterocarpi indici alkane also contains Radix Astragali saponin I～VIII (astragaloside I～VIII).Invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, diuresis granulation promoting.Be used for that the deficiency of vital energy is weak, chronic diarrhea proctoptosis, spontaneous perspiration, edema, uterine prolapse, chronic nephritis proteinuria, diabetes, open sore part disunion of a specified duration.Radix Polygoni Multiflori is the tuber of polygonum multiflorum thunb Polygonum multiflorum Thunb..Contain lecithin, emodin (emodin), chrysophanol (chrysophanol), chrysophanic acid (rhein), physcione (physcion), 2,3,5,4 '-tetrahydroxy is to styrene-2-0-β-D-glucoside (2,3,5,4 '-tetrahydroxystibene-2-0-β-D-glucoside) etc.Can be used for detoxifcation, eliminating carbuncle, relieving constipation; Be used for scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation, hyperlipidemia.The Fructus Kochiae is the fruit of chenopod Fructus Kochiae Kochiascoparia (L.) Schrad., contains triterpene saponin, fatty oil, alkaloid, flavone etc., clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.Be used for difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.Folium Isatidis is the dried leaves of cruciferae isatis Isatis indigotica Fort..Contain indirubin, indigo, N-phenyl-2-naphthylamines (N-phenyl-2-naphthylamine), cupreol, laccerol (lacerol).Heat-clearing and toxic substances removing is arranged, the function of the clear speckle of removing heat from blood.Be used for pathogenic warmth and join the army, unconsciousness due to high fever is sent out the speckle dermexanthesis, jaundice, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.Radix Paeoniae Rubra is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Contain peoniflorin (paeoniflorin), other contains a spot of Hydroxy peoniflorin (oxypaeoniflorin), lactone glucoside of Radix Paeoniae (albiflorin) and benzoic acid.Clearing away heat and cooling blood, eliminating stasis to stop pain; Be used for hematemesis and epistaxis, amenorrhea stomachache and angina pectoris.When the root that is classified as umbelliferae angelica Angelica sinensis (Oliv.) Diels.Contain ligustilide (ligustilide), Zheng Ding Xi Fu lactone (n-butylidene phthalide), ferulic acid, nicotinic acid, sucrose and several amino acids, and sesquiterpenoids etc.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
The present invention's medication of suiting the medicine to the illness is executed and is controlled, and prescription is scientific and reasonable, and crude drug source extensively is easy to get, and cost is low, safe without toxic side effect, and drug effect is fast, and is easy to use, is clinical treatment women damp heat downward flowing type pruritus vulvae, vulval eczema, the preferred medication of diseases such as vaginitis.
The specific embodiment:
The embodiment of the invention 1: selected Radix Sophorae Flavescentis 108 grams, Rhizoma Coptidis 72 grams, Cortex Phellodendri 108 grams, Pericarpium Zanthoxyli 36 grams, Fructus Cnidii 108 grams, the Radix Astragali 108 grams, Radix Polygoni Multiflori 108 grams, the Fructus Kochiae 108 grams, Folium Isatidis 108 grams, Radix Paeoniae Rubra 108 grams, Radix Angelicae Sinensis 108 gram: get above ten simply medical material decoct with water 2～3 times, each 1～2 hour, each time decoction liquor is merged filtration, get filtrate, its relative density was 1.20～1.25 clear paste when filtrate was concentrated into 40～60 ℃ of temperature, add ethanol, make and contain alcohol amount and reach 60～80%, left standstill 43～52 hours, filter, reclaim ethanol, add distilled water to regulation, add sodium laurylsulfate 3 grams again, benzoic acid 1 gram left standstill 21～26 hours, filtered, embedding promptly gets product.
The embodiment of the invention 2: selected Radix Sophorae Flavescentis 120 grams, Rhizoma Coptidis 80 grams, Cortex Phellodendri 120 grams, Pericarpium Zanthoxyli 40 grams, Fructus Cnidii 120 grams, the Radix Astragali 120 grams, Radix Polygoni Multiflori 120 grams, the Fructus Kochiae 120 grams, Folium Isatidis 120 grams, Radix Paeoniae Rubra 120 grams, Radix Angelicae Sinensis 120 gram: get above ten simply medical material decoct with water 2～3 times, each 1～2 hour, each time decoction liquor is merged filtration, get filtrate, its relative density was 1.20～1.25 clear paste when filtrate was concentrated into 40～60 ℃ of temperature, add ethanol, make and contain alcohol amount and reach 60～80%, left standstill 43～52 hours, filter, reclaim ethanol, add distilled water to regulation, add sodium laurylsulfate 4 grams again, benzoic acid 2 grams left standstill 21～26 hours, filtered, embedding promptly gets product.
The embodiment of the invention 3: selected Radix Sophorae Flavescentis 132 grams, Rhizoma Coptidis 88 grams, Cortex Phellodendri 132 grams, Pericarpium Zanthoxyli 44 grams, Fructus Cnidii 132 grams, the Radix Astragali 132 grams, Radix Polygoni Multiflori 132 grams, the Fructus Kochiae 132 grams, Folium Isatidis 132 grams, Radix Paeoniae Rubra 132 grams, Radix Angelicae Sinensis 132 gram: get above ten simply medical material decoct with water 2～3 times, each 1～2 hour, each time decoction liquor is merged filtration, get filtrate, its relative density was 1.20～1.25 clear paste when filtrate was concentrated into 40～60 ℃ of temperature, add ethanol, make and contain alcohol amount and reach 60～80%, left standstill 43～52 hours, filter, reclaim ethanol, add distilled water to regulation, add sodium laurylsulfate 5 grams again, benzoic acid 3 grams left standstill 21～26 hours, filtered, embedding promptly gets product.
The usage and dosage of its finished medicines is: external, and pruritus vulvae, vulval eczema: a 8～12ml, 2 times on the one, be applied to the pudendum affected part, wash down after 15 minutes, or add 8～12 times of amount eliminating cold for resuscitation washing bath pudendum; Vaginitis: a 8～12ml, add the dilution of 8～10 times of eliminating cold for resuscitation water after, use the vaginal douche washing vagina, 2 times on the one.
Claims (3)
1, a kind of Chinese medicine external-use lotion for the treatment of gynecological inflammation is characterized in that: it by Radix Sophorae Flavescentis etc. ten simply Chinese herbal medicine make, each Chinese herbal medicine proportioning by weight of distinguishing the flavor of is respectively:
108～132 parts of 72～88 portions of Cortex Phellodendris of 108～132 portions of Rhizoma Coptidis of Radix Sophorae Flavescentis
108～132 parts of 108～132 parts of Radixs Astragali of 36～44 parts of Fructus Cnidiis of Pericarpium Zanthoxyli
108～132 parts of 108～132 portions of Folium Isatidiss of 108～132 parts of Fructus Kochiae of Radix Polygoni Multiflori
108～132 parts of 108～132 parts of Radix Angelicae Sinensis of Radix Paeoniae Rubra.
2, according to claim 1 described a kind of Chinese medicine external-use lotion for the treatment of gynecological inflammation, it is characterized in that: main formula can also add following component and weight portion:
1～3 part in 3～5 parts of benzoic acid of sodium laurylsulfate
3, according to claim 1 described a kind of Chinese medicine external-use lotion for the treatment of gynecological inflammation, it is characterized in that: its preparation technology is: get 108～132 parts of Radix Sophorae Flavescentiss earlier, 72～88 parts of Rhizoma Coptidis, 108～132 parts of Cortex Phellodendris, 36～44 parts in Pericarpium Zanthoxyli, 108～132 parts of Fructus Cnidiis, 108～132 parts of the Radixs Astragali, 108～132 parts of Radix Polygoni Multiflori, 108～132 parts of the Fructus Kochiae, 108～132 parts of Folium Isatidiss, 108～132 parts of Radix Paeoniae Rubra, Radix Angelicae Sinensis decocts with water 2～3 times for 108～132 parts, each 1～2 hour, each time decoction liquor is merged filtration, get filtrate, when filtrate is concentrated into 40～60 ℃ of temperature, its relative density is 1.20～1.25 clear paste, add ethanol, make and contain alcohol amount and reach 60～80%, left standstill 43～52 hours, filter, reclaim ethanol, add distilled water to regulation, add 3～5 parts of sodium laurylsulfates again, 1～3 part in benzoic acid left standstill 21～26 hours, filtered, embedding promptly gets product.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610042954 CN1895429A (en) | 2006-06-12 | 2006-06-12 | Externally-applied Chinese-medicinal abstergent for treating gynecological inflammation |
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| CN 200610042954 CN1895429A (en) | 2006-06-12 | 2006-06-12 | Externally-applied Chinese-medicinal abstergent for treating gynecological inflammation |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101433655B (en) * | 2008-12-19 | 2011-07-27 | 杨洁 | Chinese medicinal composition for treating colpitis |
| CN102793828A (en) * | 2012-08-09 | 2012-11-28 | 西安太极药业有限公司 | Externally-used washing lotion for treating female vulvitis and colpitis and preparation method thereof |
| CN103127312A (en) * | 2013-03-19 | 2013-06-05 | 迟仁智 | External Antiviral and anti-pathogenic gynecological lotion and preparation technology |
-
2006
- 2006-06-12 CN CN 200610042954 patent/CN1895429A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101433655B (en) * | 2008-12-19 | 2011-07-27 | 杨洁 | Chinese medicinal composition for treating colpitis |
| CN102793828A (en) * | 2012-08-09 | 2012-11-28 | 西安太极药业有限公司 | Externally-used washing lotion for treating female vulvitis and colpitis and preparation method thereof |
| CN102793828B (en) * | 2012-08-09 | 2014-04-16 | 西安太极药业有限公司 | Externally-used washing lotion for treating female vulvitis and colpitis and preparation method thereof |
| CN103127312A (en) * | 2013-03-19 | 2013-06-05 | 迟仁智 | External Antiviral and anti-pathogenic gynecological lotion and preparation technology |
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