CN101244149B - Chinese medicine pill for treating hypertrophy of the prostate and acute or chronic prostatitis - Google Patents
Chinese medicine pill for treating hypertrophy of the prostate and acute or chronic prostatitis Download PDFInfo
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- CN101244149B CN101244149B CN2008100492960A CN200810049296A CN101244149B CN 101244149 B CN101244149 B CN 101244149B CN 2008100492960 A CN2008100492960 A CN 2008100492960A CN 200810049296 A CN200810049296 A CN 200810049296A CN 101244149 B CN101244149 B CN 101244149B
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Abstract
The invention relates to a Chinese medicine pill for the treatment of prostatic hypertrophy and acute and chronic prostatitis, effectively solving the problem of therapeutic effect on prostatic hypertrophy and acute and chronic prostatitis treatment, comprising scutelarria 130 to 155g, coptis 100 to 125g, phellodendron bark 75g to 95g, weeping forsythis 100g to 125g, barbated skullcup herb 90g to 110g, gardenia 50g to 65g, cortex moutan 75g to 95g, hirudo 50g to 65g, licorice 100 to 125g, angelic sinensis 40g to 60g, red peony root 40g to 60g, solanum nigrum 40g to 60g, epimedy 70g to 90g, which adopts the technical proposal that: the thirteen herbal ingredients are crashed into powder, sieved, mixed evenly, watered, and then dried to make Chinese medicine pills. The Chinese medicine pill has the advantages of scientific prescription formulation, convenience in use, capability of curing prostatic hypertrophy, acute and chronic prostatitis and urethritis; accurate clinical therapeutic effect for urodynia, urgency of urination, dribbling twinge, not finishing urination, waist and abdomen discomfort caused by urinary infection; innovation and great economical and social benefits.
Description
One, technical field
The present invention relates to field of medicaments, a kind of especially Chinese medicine pill for the treatment of prostate hyperplasia and acute and chronic prostatitis.
Two, background technology
Stranguria is the card of common pilosity, and is evil for damp and hot poison, pents up the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, and qi-blood disharmony, disturbance in water passage forms.The stranguria of prostate hyperplasia and acute and chronic prostatitis, belong to the smart turbid category of the traditional Chinese medical science, it is evil mostly to be the damp and hot poison of diseases caused by exogenous pathogenic factor, internal injury food and drink libido is done, when detoxifying to controlling with clearing away heat-damp and promoting diuresis, the stasis of blood of living, along with the continuous development of medical science, many treatment prostate hyperplasia and prostatitic medicine have appearred, but all unsatisfactory.Because such disease clinical symptoms complexity is various, outbreak repeatedly easily, protracted course of disease has all brought unthinkable misery and helpless for patient's physical and mental health, therefore presses for a kind of new medicine.
Three, summary of the invention
At above-mentioned situation, the present invention's purpose just provides a kind of Chinese medicine pill for the treatment of prostate hyperplasia and acute and chronic prostatitis, can effectively solve the treatment problem of prostate hyperplasia and acute and chronic prostatitis, the technical scheme of its solution is, according to the Chinese materia medica principle, this invention is by Radix Scutellariae 130-155g, Rhizoma Coptidis 100-125g, Cortex Phellodendri 75-95g, Fructus Forsythiae 100-125g, Herba Scutellariae Barbatae 90-110g, Fructus Gardeniae 50-65g, Cortex Moutan 75-95g, Hirudo 50-65g, Radix Glycyrrhizae 100-125g, Radix Angelicae Sinensis 40-60g, Radix Paeoniae Rubra 40-60g, Herba Solani Nigri 40-60g, Herba Epimedii 70-90g makes, at first above-mentioned 13 herbal medicines are ground into fine powder altogether, sieve, mix homogeneously, then with water pill, Chinese medicine pill is made in oven dry.Prescription science of the present invention, therapeutic effect is good, taking convenience is the good medicine of treatment prostate hyperplasia and acute and chronic prostatitis, urethritis, to dysurea, urgent micturition, sound of rain pattering twinge due to the urinary system infection, desire to the greatest extent, disease clinical efficacy such as waist abdomen discomfort is definite.It is succeeded in developing, and is an innovation on the Chinese medicine, and economic and social benefit is huge.
Four, the specific embodiment
Below in conjunction with practical situation the specific embodiment of the present invention is elaborated.
Provide by technical scheme, the present invention is made by Radix Scutellariae 130-155g, Rhizoma Coptidis 100-125g, Cortex Phellodendri 75-95g, Fructus Forsythiae 100-125g, Herba Scutellariae Barbatae 90-110g, Fructus Gardeniae 50-65g, Cortex Moutan 75-95g, Hirudo 50-65g, Radix Glycyrrhizae 100-125g, Radix Angelicae Sinensis 40-60g, Radix Paeoniae Rubra 40-60g, Herba Solani Nigri 40-60g, Herba Epimedii 70-90g, at first 13 herbal medicines are ground into fine powder altogether, sieve, mix homogeneously, with water pill, Chinese medicine pill is made in oven dry then.In case of necessity, also available Mel is with the Chinese medicine pill polishing.
Embodiment 1, the present invention in the specific implementation, be to make by Radix Scutellariae 130g, Rhizoma Coptidis 100g, Cortex Phellodendri 75g, Fructus Forsythiae 100g, Herba Scutellariae Barbatae 90g, Fructus Gardeniae 50g, Cortex Moutan 75g, Hirudo 50g, Radix Glycyrrhizae 100g, Radix Angelicae Sinensis 40g, Radix Paeoniae Rubra 40g, Herba Solani Nigri 40g, Herba Epimedii 70g, at first 13 herbal medicines are ground into fine powder altogether, cross 80 mesh sieves, mix homogeneously, then with water pill, Chinese medicine pill is made in oven dry below 65 ℃, also can utilize Mel with the Chinese medicine pill polishing.
Embodiment 2, the present invention is made by Radix Scutellariae 141g, Rhizoma Coptidis 113g, Cortex Phellodendri 85g, Fructus Forsythiae 113g, Herba Scutellariae Barbatae 99g, Fructus Gardeniae 56g, Cortex Moutan 85g, Hirudo 56g, Radix Glycyrrhizae 111g, Radix Angelicae Sinensis 50g, Radix Paeoniae Rubra 50g, Herba Solani Nigri 50g, Herba Epimedii 80g, at first 13 herbal medicines are ground into fine powder altogether, cross 80 mesh sieves, mix homogeneously, then with water pill, 55 ℃ of oven dry, make Chinese medicine pill, with Mel with the Chinese medicine pill polishing.
Embodiment 3, the present invention is made by Radix Scutellariae 155g, Rhizoma Coptidis 125g, Cortex Phellodendri 95g, Fructus Forsythiae 125g, Herba Scutellariae Barbatae 125g, Rhizoma Dioscoreae Septemlobae 155g, Fructus Gardeniae 65g, Cortex Moutan 95g, Hirudo 65g, Radix Glycyrrhizae 125g, Radix Angelicae Sinensis 60g, Radix Paeoniae Rubra 60g, Herba Solani Nigri 60g, Herba Epimedii 90g, at first 13 herbal medicines are ground into fine powder altogether, cross 80 mesh sieves, mix homogeneously, then with water pill, 60 ℃ of oven dry, make Chinese medicine pill, with Mel with the Chinese medicine pill polishing.
The honey that Mel preferably adopts Apidae insecticide apis cerana Apis cerana Fabricius or apis mellifera Linnaeus Apis mllefera Linnaeus to be made.Refine into middle honey through technologies such as heating, filtrations during use.
The present invention is the buff watered pill; The feeble QI raw meat, bitter in the mouth.
Rhizoma Coptidis, Cortex Phellodendri etc. contain than multifilament among the present invention, and Hirudo is an animal drug, all are difficult for pulverizing, so be advisable to mix to pulverize.
Contain volatile ingredient (Cortex Moutan) among the present invention, so bake out temperature should not be above 65 ℃.
In said medicine, wherein:
Radix Scutellariae: this product is the dry root of labiate Radix Scutellariae Scutellaria baicalensis Ceorgi.Mainly contain baicalin (Baicalin), noroxylin (baicalin, Baicalein) and wogonin (Wogonin), wogonoside (Wogonoside) and neobaicalein Flavonoid substances such as (Neobaicalein) and effective monomer S, B, G
2Also contain compositions such as volatile oil, aminoacid, Fructus Vitis viniferae sugar and starch in addition.
Rhizoma Coptidis: this product is the dry rhizome of ranunculaceae plant Rhizoma Coptidis Coptis ohinensis Franch., Coptis deltoidea C.Y.Cheng et Hsiao Coptis deltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall Coptis teeta Wall..Mainly contain berberine (Berberine), coptisine (Coptisine), 13-methyl-.psi.-coptisine. multiple alkaloids such as (Worenine), still contain obacunone (Obakunone), ferulic acid compositions such as (Ferulicacid) in addition.
Cortex Phellodendri: this product is the dry bark of cloud savoury herb wampee Phellodendron chinense Schneid. or Cortex Phellodendri Phellodendron amurense Rupr..Contain berberine (Berberine), phellodendrine (Phellodendrine), jateorhizine (jatrorrhizine) etc.; The wampee bark contains compositions such as berberine, magnoflorine, phellodendrine, lactone.
Fructus Forsythiae: this product is the dry fruit of Oleaceae plant Forsythia suspensa (Thunb.) Vahl.Mainly contain forsythol (Forsythol), phillyrin (Phillyrin), oleanolic acid compositions such as (Oleanolicacid), still contain pinoresinol, multiple hydro carbons, aldoketones, alcohol ester ethers volatile ingredient etc. in addition.
Herba Scutellariae Barbatae: this product is the dry herb of labiate Herba Scutellariae Barbatae Scutellaria barbata D.Don.Contain compositions such as carthamin (Carthamidin), isocarthamidin (lsocarthamidin), baicalin (Scutellarein), scutellarin (Scutellarein) and polysaccharide.
Fructus Gardeniae: this product is the dry mature fruit of Maguireothamnus speciosus Fructus Gardeniae Gardenia Jasminoides Ellis.Mainly contain jasminoidin (geniposide, Geniposide), composition such as the different jasminoidin of carboxylic, genipin, deacetylate Herba Plantaginis methyl oxalate, mountain mast glycosides, crocin.
Cortex Moutan: this product is the dry root bark of ranunculaceae peony Paeonia suffruticosa Andr..Contain compositions such as paeonol (Paeonol), Paeonia suffruticosa powder glycosides (Paeonside), peoniflorin, oxypaeoniflorin, gallic acid, volatile oil, benzoic acid, sucrose.
Hirudo: this product is the dry body of Hirudinidae animal whitmania Whitmania pigra Whitman, Hirudo Hirudonipponica Whitman or Folium Salicis Babylonicae Hirudo Whitmania acranulata Whitman.Mainly contain protein, hirudin (hirudin) and various trace elements and aminoacid.
Radix Glycyrrhizae: this product is the dry root and rhizome of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza grabra L..Mainly contain compositions such as glycyrrhizin (Gly-cyrrhicacid), glycyrrhizic acid, enoxolone.
Radix Angelicae Sinensis: be the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Contain basic lactone (ligusiilide), n-butene acyl lactone (n-butylidene phthalide), ferulic acid, nicotinic acid, sucrose and several amino acids, and sesquiterpenoids etc.
Radix Paeoniae Rubra: be the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall. or river Radix Paeoniae Rubra Paeoniaveitchii Lynch.Contain paeoniflorin (paeoniflorin).
Herba Solani Nigri: for the aerial parts of Solanaceae nightshade Herba Solani Nigri Solanum nigrum L., with all herbal medicine.Contain solanine (solanigrine), Australia's solanamine (oslasodine), Herba Solani Nigri and decide alkali (solanigridine), Saponin, vitamin C, resin.
Herba Epimedii: be the aerial parts of the little Pi plant arrow leaf Herba Epimedii Epimedium segittatum of section (Sitb.etZucc.) Maxim..Stem and leaf contains icariine (icariin), epimedoside A (epinedoside A); Rhizome and root contain noricariin (noricarliln), icariresinol (I-cariresinol).
Effective combination of medicine of the present invention is supported mutually, has heat clearing and damp drying, the stasis of blood of living detoxifcation, be effective to prostate hyperplasia, urethritis, card sees frequency of micturition, sound of rain pattering twinge, desire to the greatest extent etc., receives better curative effect through clinical, and concrete relevant relevant clinical data of the present invention is as follows:
One, selects the standard of case
With prostate hyperplasia and acute and chronic prostatitis is example:
Prostate hyperplasia claims prostate to give birth to disease again, is the hypertrophy of body of gland around the above prostatic urethra of seminal colliculus.Its outgrowth main cause is an endocrine regulation, and is relevant with the Developmental and Metabolic Disorder of gonadal hormone.Be more common in the old people.
Prostatitis is meant the active chronic inflammation due to prostate specific and the non-special infection, thus whole body that causes or local symptom.According to course of disease branch, can be divided into acute prostatitis and chronic prostatitis.
Acute prostatitis: cardinal symptom is a perineal position distending pain discomfort, and lower abdomen dull pain is more obvious, can be to lumbosacral region, penis portion and thigh root radiation.Symptoms such as frequent micturition, urgent micturition, dysurea or hematuria can appear as causing then because of urinary system infection.It is more anxious to fall ill, can be with heating, shiver with cold, anorexia, General Symptoms such as weak.Check that the peripheral blood leukocyte increases, visible a large amount of leukocyte in the urine.Rectal touch can be touched the prostate of enlargement, and tangible tenderness is arranged, and when forming abscess fluctuation can be arranged.
Chronic prostatitis: cardinal symptom is frequent micturition and vesical tenesmus and urethra scorching hot and itches.Pain is distending pain and take out pain often, to the radiation of Glans penis and perineal position, and has on the pubis and the lumbosacral region discomfort.The patient often has prostatorrhoea, and pilosity is born in and is urinated terminal or stool firmly the time, and urethral orifice flows out white secretions.Rectal touch prostate soft or hard inequality has mild tenderness.
Every have an above-mentioned symptom, all as the standard of selecting case.
Two, diagnostic criteria
1, bladder and urethral stimulant symptom have frequent micturition, dysurea, urgent micturition, urethra scorching hot, urinate endless, dripping, and dysuria is arranged sometimes.
2, urethra drips white: be more common in urinate in not or when stool urethral orifice adularescent secretions ooze.
3, pain symptom: be more common in lumbosacral region, the lower abdomen, perineal position, pubis portion, femur ditch, femoribus internus and testis etc., general pain is inviolent, is intermittent.
4, sexual dysfunction: libido descends, premature ejaculation, sexual impotence, seminal emission, painful ejaculation etc.
5 neurasthenia symptoms; Dizzy, weak, dreaminess, insomnia, fatigue and weak etc.
Three, therapeutic scheme
The patient takes the present invention, and every day three times, each 6g during taking, is forbidden pungent or tobacco and wine, or food excitatory, and one month is a course of treatment.Observe clinical symptoms change before and after taking the present invention, judge curative effect.
Four, efficacy assessment standard
Cure in the recent period: dysurea, urgent micturition, frequent micturition disappear, lower abdomen contracture or lumbago lower limb be heavy to be stranded and to alleviate or disappears, and part patient influence sexual disorder because of inflammatory stimulus, also gradually in take a turn for the better or recovery normally.
Effectively: symptom alleviates than before to some extent.
Invalid: take before and after the present invention, every index and symptom do not have improvement.
Five, statistical disposition
By above-mentioned therapeutic scheme, clinically use through 252 routine patients, 20～78 years old age, 20～39 years old patient's 84 example wherein, 40～49 years old 76 example, 50～59 years old 44 example, all the other are patient more than 60 years old, the course of disease 6 months～9 years.Diagnosis and dialectical standard are divided slight 72 examples, moderate 108 examples, severe 52 examples all according to health " new Chinese medicine clinical research guideline " promulgated by the ministries or commissions of the Central Government.
The present invention treats prostate hyperplasia or the caused clinical symptoms of active chronic inflammation, obtains curative effect preferably, treatment statistical result: cure 120 examples in the recent period and account for (48%); Produce effects 80 examples account for (32%); Effective 32 examples (12.7%); Invalid 10 examples (7.9%); Total effective rate 92.06%.And not finding toxic and side effects, is a kind of effective and safe Chinese medicine preparation, sees table 1 for details.
Table 1 clinical efficacy statistical table n (%)
| The sick kind | n | Cure in the recent period | Produce effects | Effectively | Invalid | Total effective rate |
| Prostate hyperplasia and active chronic inflammation | 252 | 120(48) | 80(32) | 32(12.7) | 10(7.9) | 232(92.06) |
| Add up to | 252 | 120(48) | 80(32) | 32(12.7) | 10(7.9) | 232(92.06) |
Six, conclusion
Shown that by above-mentioned the present invention has heat clearing and damp drying, the stasis of blood of living function of detoxification is in treatment prostate hyperplasia or the caused clinical symptoms of active chronic inflammation, obtain curative effect preferably, stranguria that the present invention controls, and damp and hot poison is evil, pent up the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, qi-blood disharmony, disturbance in water passage forms.Control and work as heat clearing and damp drying, the stasis of blood of living detoxifcation.Radix Scutellariae, Rhizoma Coptidis, Cortex Phellodendri bitter cold among the present invention are returned through liver, gallbladder, bladder, the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, and the merit of tool heat clearing and damp drying, eliminating fire and detoxication is monarch drug altogether; Be aided with Fructus Forsythiae, Herba Scutellariae Barbatae removing summer-heat pyretic toxicity, the BIXUAN dampness removing goes turbid, the Fructus Gardeniae clearing away heat-fire, and four share to help the merit of principal agent eliminating damp-heat, are ministerial drug altogether.The heresy of right pyretic toxicity, easy impairment of YIN blood, so with the Cortex Moutan clearing away heat and cooling blood to protect cloudy liquid; Damp is sticky, easily hinders mechanism of qi, the hyperamization stasis of blood stagnation of QI, so with the Hirudo blood stasis and smoothing collaterals of living, make the stasis of blood go that then gas is smooth, the two is adjuvant drug altogether.Make with Radix Glycyrrhizae, anti-its of product that both can delay bitter cold injures one's stomach, but coordinating the actions of various ingredients in a prescription again, Radix Angelicae Sinensis, sweet, hot, temperature is returned liver, the heart, spleen channel, can enrich blood and invigorate blood circulation, loosening bowel to relieve constipation; Radix Paeoniae Rubra, hardship is slightly cold, and returns Liver Channel, clearing away heat and cooling blood, eliminating stasis to stop pain; Herba Solani Nigri, hardship, cold, heat-clearing and toxic substances removing, inducing diuresis to remove edema; The Herba Epimedii kidney-replenishing, strengthing aitch bone, wind-damp dispelling.Take a broad view of the present invention, heat clearing away and not injuring one's stomach, dampness removing and impairment of body fluid not, the stasis of blood of living is beneficial to regulates the flow of vital energy, removing heat from blood is beneficial to Bao Yin, silk silk incision pathogenesis, really for the good recipe of stranguria treatment also.Make fire lowering and heat removing, turbid damp must disappear, follow through send out disease all, all can be corresponding and heal.Refining formula of the present invention, curative effect is sure, and craft science is quality controllable, avirulence, expense is low, and economic and social benefit is huge.
Claims (4)
1. Chinese medicine pill for the treatment of prostate hyperplasia and acute and chronic prostatitis, it is characterized in that, said Chinese medicine pill is to be made by Radix Scutellariae 130-155g, Rhizoma Coptidis 100-125g, Cortex Phellodendri 75-95g, Fructus Forsythiae 100-125g, Herba Scutellariae Barbatae 90-110g, Fructus Gardeniae 50-65g, Cortex Moutan 75-95g, Hirudo 50-65g, Radix Glycyrrhizae 100-125g, Radix Angelicae Sinensis 40-60g, Radix Paeoniae Rubra 40-60g, Herba Solani Nigri 40-60g, Herba Epimedii 70-90g, at first 13 herbal medicines are ground into fine powder altogether, sieve, mix homogeneously, then with water pill, Chinese medicine pill is made in oven dry.
2. a kind of Chinese medicine pill for the treatment of prostate hyperplasia and acute and chronic prostatitis according to claim 1, it is characterized in that, said Chinese medicine pill is to be made by Radix Scutellariae 130g, Rhizoma Coptidis 100g, Cortex Phellodendri 75g, Fructus Forsythiae 100g, Herba Scutellariae Barbatae 90g, Fructus Gardeniae 50g, Cortex Moutan 75g, Hirudo 50g, Radix Glycyrrhizae 100g, Radix Angelicae Sinensis 40g, Radix Paeoniae Rubra 40g, Herba Solani Nigri 40g, Herba Epimedii 70g, at first 13 herbal medicines are ground into fine powder altogether, cross 80 mesh sieves, mix homogeneously, then with water pill, Chinese medicine pill is made in 65 ℃ of oven dry.
3. a kind of Chinese medicine pill for the treatment of prostate hyperplasia and acute and chronic prostatitis according to claim 1, it is characterized in that, said Chinese medicine pill is to be made by Radix Scutellariae 141g, Rhizoma Coptidis 113g, Cortex Phellodendri 85g, Fructus Forsythiae 113g, Herba Scutellariae Barbatae 99g, Fructus Gardeniae 56g, Cortex Moutan 85g, Hirudo 56g, Radix Glycyrrhizae 111g, Radix Angelicae Sinensis 50g, Radix Paeoniae Rubra 50g, Herba Solani Nigri 50g, Herba Epimedii 80g, at first 13 herbal medicines are ground into fine powder altogether, cross 80 mesh sieves, mix homogeneously, then with water pill, Chinese medicine pill is made in 55 ℃ of oven dry.
4. a kind of Chinese medicine pill for the treatment of prostate hyperplasia and acute and chronic prostatitis according to claim 1 is characterized in that, said Chinese medicine pill with Mel with the Chinese medicine pill polishing.
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| CN101822753A (en) * | 2010-05-26 | 2010-09-08 | 王旭亮 | Medicine for treating prostatitis and preparation method thereof |
| CN104887773A (en) * | 2014-03-05 | 2015-09-09 | 鲍旭刚 | Prostatitis treating drug and preparation method thereof |
| CN106420983B (en) * | 2016-11-30 | 2019-11-26 | 天津中医药大学 | Purposes of the coptis extract in the drug for preparing the lower urinary tract symptom for preventing and/or treating benign prostatic hyperplasis and its induction |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1185322A (en) * | 1996-12-19 | 1998-06-24 | 李启忠 | Qi-tonifying and diuresis decoction of Chinese medicine and preparation method thereof |
| CN101164581A (en) * | 2006-10-17 | 2008-04-23 | 臧育增 | Traditional Chinese medicine for treating acute and chronic prostate disease and preparation technology thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1185322A (en) * | 1996-12-19 | 1998-06-24 | 李启忠 | Qi-tonifying and diuresis decoction of Chinese medicine and preparation method thereof |
| CN101164581A (en) * | 2006-10-17 | 2008-04-23 | 臧育增 | Traditional Chinese medicine for treating acute and chronic prostate disease and preparation technology thereof |
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