CN1887255A - Compound taurine injection and its prepn process and use - Google Patents
Compound taurine injection and its prepn process and use Download PDFInfo
- Publication number
- CN1887255A CN1887255A CN 200610014918 CN200610014918A CN1887255A CN 1887255 A CN1887255 A CN 1887255A CN 200610014918 CN200610014918 CN 200610014918 CN 200610014918 A CN200610014918 A CN 200610014918A CN 1887255 A CN1887255 A CN 1887255A
- Authority
- CN
- China
- Prior art keywords
- injection
- taurine
- compound
- water
- aminophenazone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention discloses compound taurine injection and its preparation process and use. The compound taurine injection is prepared through the following steps: heating water for injection of 20-80 ml to 50-90 deg.c; adding and dissolving taurine in 0.5-7 g, aminopyrine in 1-8 g, anhydrous sodium sulfite in 0.05-1 g, disodium EDTA in 0.005-0.05 g and sodium chloride in 0.05-2 g; adding water for injection to near 1000 ml; regulating pH value to 4-7; adding water for injection to 1000 ml; and mixing homogeneously. The compound taurine injection has raised curative effect and wide clinical application, and may be used in preparing medicine for treating fever, dyspnoea and poor appetite of pig and other livestock.
Description
Technical field
The present invention relates to a kind of compound taurine injection, Preparation method and use.
Background technology
Porcine nameless high-fever is one of modal disease of swinery, is seriously restricting the development of pig industry.The choice drug of treatment porcine hyperthermia in is listed dipyrone in various places in decades, but owing to prolonged and repeated use, causes the pig body that medicine has been produced toleration, and reduced curative effect.
Summary of the invention
The objective of the invention is to overcome deficiency of the prior art, a kind of tolerific taurine injection of avoiding is provided.
Second purpose of the present invention provides a kind of preparation method of taurine injection.
The 3rd purpose of the present invention provides the application of a kind of taurine injection at preparation treatment heating, dyspnea and loss of appetite medicine.
Technical scheme of the present invention is summarized as follows:
A kind of compound taurine injection, make with following method:
The water for injection of getting 20-80ml is heated to 50-90 ℃; add the 0.5-7g taurine successively; the 1-8g aminophenazone; 0.05-1g anhydrous sodium sulfite, 0.005-0.05g disodiumedetate, the dissolving of 0.05-2g sodium chloride; add the injection water closely to 1000ml; adjusting pH is 4-7, adds the injection water to 1000ml, mixing.
Preferably: described taurine is 4g, and described aminophenazone is 4g.
Preferably: described anhydrous sodium sodium bisulfate is 0.1g, and described disodiumedetate is 0.01g, and described sodium chloride is 0.6g.
A kind of preparation method of compound taurine injection comprises the steps:
The water for injection of getting 20-80ml is heated to 50-90 ℃; add the 0.5-7g taurine successively; the 1-8g aminophenazone; 0.05-1g anhydrous sodium sulfite, 0.005-0.05g disodiumedetate, the dissolving of 0.05-2g sodium chloride; add the injection water closely to 1000ml; adjusting pH is 4-7, adds the injection water to 1000ml, mixing.
Preferably: described taurine is 4g, and described aminophenazone is 4g.
Preferably: described anhydrous sodium sodium bisulfate is 0.1g, and described disodiumedetate is 0.01g, and described sodium chloride is 0.6g.
A kind of compound taurine injection is in the application of preparation treatment heating, dyspnea and loss of appetite medicine.
A kind of compound taurine injection of the present invention heightens the effect of a treatment owing to adopt compound preparation, and clinical practice is extensive, can be in the application of preparation treatment heating, dyspnea and loss of appetite medicine.
The specific embodiment
The present invention is further illustrated below in conjunction with specific embodiment.
Embodiment 1
A kind of preparation method of compound taurine injection comprises the steps:
The water for injection of getting 50ml is heated to 60 ℃, adds the 4g taurine successively, the 4g aminophenazone, and 0.1g anhydrous sodium sulfite, 0.01g disodiumedetate, the dissolving of 0.6g sodium chloride add the injection water to 1000ml, and regulating pH is 6, mixing.
Embodiment 2
A kind of preparation method of compound taurine injection comprises the steps:
The water for injection of getting 20ml is heated to 50 ℃, adds the 7g taurine successively, the 1g aminophenazone, and 0.05g anhydrous sodium sulfite, 0.05g disodiumedetate, the dissolving of 0.05g sodium chloride add the injection water to 1000ml, and regulating pH is 4, mixing.
Embodiment 3
A kind of preparation method of compound taurine injection comprises the steps:
The water for injection of getting 80ml is heated to 90 ℃, adds the 0.5g taurine successively, the 8g aminophenazone, and 1g anhydrous sodium sulfite, 0.005g disodiumedetate, the dissolving of 2g sodium chloride add the injection water to 1000ml, and regulating pH is 7, mixing.
The color of medicinal liquid is colourless or almost colourless clear liquid.
Embodiment 4
Clinical trial:
Picked at random does not have other bacteriovirus infections and piglet that stress situation, but only 100 of the pigs that hyperpyrexia disease symptom, dyspnea and loss of appetite are arranged, according to body condition, term, close situation was divided into four groups, select different injection for use, B group once amount injection 10ml, C group is once measured once amount injection 5ml of injection 10ml, D group.
Its therapeutic effect contrast sees the following form.
Animal compound taurine, aminophenazone injection group and other injection for treating effect comparison tables
| Numbering | Group | Mortality rate % | Inefficiency % | Effective percentage % | Cure rate % | Symptom pig's head number is arranged during end | The relative weight gain rate % |
| A | Do not treat (matched group) | 2 | - | - | - | - | - |
| B | The aminophenazone treatment | 1 | 3.5 | 72.3 | 70.2 | 4 | 70.2 |
| C | The taurine treatment | 1 | 5.6 | 75.6 | 74.3 | 5 | 74.2 |
| D | The embodiment of the invention 1 treatment | 0 | 1.2 | 98.3 | 90.8 | 1 | 89.0 |
This result of the test is analyzed by statistics, taurine treatment group and aminophenazone treatment significant difference (P≤0.05).The present invention and aminophenazone treatment group difference is (P≤0.01) extremely significantly.
Claims (7)
1. compound taurine injection is characterized in that making with following method:
The water for injection of getting 20-80ml is heated to 50-90 ℃; add the 0.5-7g taurine successively; the 1-8g aminophenazone; 0.05-1g anhydrous sodium sulfite, 0.005-0.05g disodiumedetate, the dissolving of 0.05-2g sodium chloride; add the injection water closely to 1000ml; adjusting pH is 4-7, adds the injection water to 1000ml, mixing.
2. a kind of compound taurine injection according to claim 1 is characterized in that described taurine is 4g, and described aminophenazone is 4g.
3. a kind of compound taurine injection according to claim 1 and 2 is characterized in that described anhydrous sodium sodium bisulfate is 0.1g, and described disodiumedetate is 0.01g, and described sodium chloride is 0.6g.
4. the preparation method of a compound taurine injection is characterized in that comprising the steps:
The water for injection of getting 20-80ml is heated to 50-90 ℃; add the 0.5-7g taurine successively; the 1-8g aminophenazone; 0.05-1g anhydrous sodium sulfite, 0.005-0.05g disodiumedetate, the dissolving of 0.05-2g sodium chloride; add the injection water closely to 1000ml; adjusting pH is 4-7, adds the injection water to 1000ml, mixing.
5. the preparation method of a kind of compound taurine injection according to claim 4 is characterized in that described taurine is 4g, and described aminophenazone is 4g.
6. according to the preparation method of claim 4 or 5 described a kind of compound taurine injections, it is characterized in that described anhydrous sodium sodium bisulfate is 0.1g, described disodiumedetate is 0.01g, and described sodium chloride is 0.6g.
7. the described a kind of compound taurine injection of one of claim 1-3 is preparing the application for the treatment of heating, dyspnea and loss of appetite medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610014918 CN1887255A (en) | 2006-07-27 | 2006-07-27 | Compound taurine injection and its prepn process and use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610014918 CN1887255A (en) | 2006-07-27 | 2006-07-27 | Compound taurine injection and its prepn process and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1887255A true CN1887255A (en) | 2007-01-03 |
Family
ID=37576534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610014918 Pending CN1887255A (en) | 2006-07-27 | 2006-07-27 | Compound taurine injection and its prepn process and use |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1887255A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101244137B (en) * | 2008-02-28 | 2011-05-04 | 郑明刚 | Medicament for treating pulmonitis, and high fever, lower fever, and preparation method |
-
2006
- 2006-07-27 CN CN 200610014918 patent/CN1887255A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101244137B (en) * | 2008-02-28 | 2011-05-04 | 郑明刚 | Medicament for treating pulmonitis, and high fever, lower fever, and preparation method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1785257A (en) | Tincture for trenting fungus dermatosis | |
| CN101015542A (en) | Compound paracetamol injection for livestock and process for preparing same | |
| CN101664381A (en) | Preparation method of in-situ gel sustained-release preparation for treating Bovine mastitis | |
| CN101301291B (en) | Compound enrofloxacin injection for animals and preparation thereof | |
| CN1879626A (en) | Compound Vitamin B injection and preparation method thereof | |
| CN1887255A (en) | Compound taurine injection and its prepn process and use | |
| CN1879710A (en) | Method for preparing rhubarb sulfur gel agent | |
| CN1245152C (en) | Nano-silver aqueous solution preparation and its preparation method, use and using method | |
| CN111467311A (en) | Doxycycline hydrochloride soluble powder and preparation method thereof | |
| CN102793713A (en) | Lincomycin hydrochloride-spectinomycin sulfate injection and preparation method thereof | |
| CN101297793A (en) | Injection for curing diarrhea of pig and preparation thereof | |
| CN1861084A (en) | Compound fluorophenylnico injection, prepn. method and use thereof | |
| CN101062014A (en) | Compound hydrochloride doxycycline injection for animals and the preparing method thereof | |
| CN1111411C (en) | Antibacterial clindamycin phosphate powder injection and its preparing process | |
| CN1879633A (en) | Compound sulfamethoxazole injection for animal, its preparation method and use | |
| CN1264517C (en) | Application of Netilmicin sulfate in preparation of eye drops | |
| CN1843358A (en) | Ketoconazole eye drops and fabricating method thereof | |
| CN103655593A (en) | Composite medicine preparation for prevention and treatment of bacterium and virus polyinfection diseases of livestock as well as preparation method and application thereof | |
| CN1879618A (en) | Compound paracetamol injection for animal and preparation method thereof | |
| CN111603448A (en) | Compound doxycycline hydrochloride soluble powder and preparation method thereof | |
| CN1872069A (en) | Injection of compound aminophylline for animal use, and preparation method | |
| CN1244320C (en) | Nose spray agent | |
| CN1857718A (en) | Nerve growth factor injection | |
| CN1872027A (en) | Injection of vitriolic berberine for animal use, preparation and usage | |
| CN1232248C (en) | Combined sustained release agent and preparation thereof for preventing and treating livestock helminth, acarid and ectosarc disease |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20070103 |