CN1245152C - Nano-silver aqueous solution preparation and its preparation method, use and using method - Google Patents
Nano-silver aqueous solution preparation and its preparation method, use and using method Download PDFInfo
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- CN1245152C CN1245152C CN 200410022463 CN200410022463A CN1245152C CN 1245152 C CN1245152 C CN 1245152C CN 200410022463 CN200410022463 CN 200410022463 CN 200410022463 A CN200410022463 A CN 200410022463A CN 1245152 C CN1245152 C CN 1245152C
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Abstract
The present invention relates to a nano silver water solution preparation which is made from ingredients: 0.05 to 1.5 wt% of nano silver, 0.5 to 1.5 wt% of dispersing agent, 0.05 to 0.2 wt% of reductant, 0.5 to 10 wt% of stabilizer, and 1000 wt% of deionized water. The present invention also relates to a method for preparing the nano silver water solution preparation, a purpose for treating male venereal diseases, and a use method by injecting medicines into urinary bladders through urethras. All reductants and stabilizers in the nano silver water solution preparation are licensed by FDA of US or the ministry of health of China. The nano silver water solution preparation can be applied to additives of foods or medicines, the dosage is smaller than the largest limited quantity, and thus, the nano silver water solution preparation has no stimulation function on human bodies, and can not cause adverse reaction of poisoning and the like after being used for a long term.
Description
(1) technical field:
The present invention relates to a kind of nanometer silver preparation, particularly a kind of nano-silver water solution preparation with antiinflammatory, antibacterial action; The invention still further relates to preparation method, purposes and the using method of above-mentioned nano-silver water solution preparation.
(2) background technology:
Modern medicine confirms, nanometer silver has outstanding antibacterial ability, has a broad antifungal spectrum, to the Glanz positive bacteria, the Glanz negative bacterium, fungus, anaerobe all has tangible antibacterial functions, especially to the same tool sterilizing ability of drug resistance pathogenic bacterium, as staphylococcus aureus, escherichia coli, gonococcus, candida albicans, bacillus pyocyaneus, micrococcus scarlatinae, bacillus subtilis, pneumobacillus, pathogenic bacterium such as anaerobe, also can kill chlamydia trachomatis, and avirulence, no anaphylaxis, nonirritant, therefore be made into powder, antiinflammatory film and gel are used clinically, as application number is 01110767.7, name is called " aggregation-preventing nanometer wide-spectrum antibacterial silve powder and inductrial production process ", application number is 01129505.8, name is called " nanometer silver gynaecopathia antimicrobial inflammation-relieving film and industrialized producing technology thereof " and application number is 01129507.4, name is called " nanometer silver antimicrobial inflammation-relieving gel for curing prostatitis and industrialized producing technology thereof ", these powder, antibacterial film and gel can be used for the treatment of vaginitis, male prostatitis and senile organic prostatitis, its using method is by vagina or the direct administration of rectum, because powder, antiinflammatory film and gel all can't inject urethra and bladder, therefore still unmanned nanometer silver preparation for treating male venereal disease and urethra and the bladder disease used.
(3) summary of the invention:
The present invention will disclose a kind of nano-silver water solution preparation that can inject urethra and bladder.The present invention also will disclose preparation method, purposes and the using method of above-mentioned nano-silver water solution preparation.
The composition and the weight fraction of nano-silver water solution preparation of the present invention are as follows:
Nanometer silver 0.05～1.5, dispersant 0.5～1.5, Reducing agent 0.05～0.2, stabilizing agent are 0.5～10, deionized water 1000.
The preferred weight of above-mentioned each composition of aqueous solution preparation is divided into:
Nanometer silver 0.08～1.2, dispersant 0.8～1.2, Reducing agent 0.1～0.15, stabilizing agent are 0.8～2, deionized water 1000.
The optimum weight of above-mentioned each composition of nano-silver water solution preparation is divided into:
Nanometer silver 0.35, dispersant 1, Reducing agent 0.12, stabilizing agent are 1, deionized water 1000.
Reducing agent generally uses sulphite described in the above-mentioned nano-silver water solution preparation, preferably uses sodium metabisulfite or sodium sulfite; Described stabilizing agent preferably uses V
E,, V
COr different V
CIn a kind of, or between them with any proportional quantity, the mixture that is arbitrarily made with; Described dispersant generally uses the high molecular polymer class, and surfactant-based and organic acid dispersant preferably uses triethanolamine.
Nano-silver water solution preparation of the present invention can be made according to a conventional method, but its preparation method is best:
1) takes by weighing raw material in proportion;
2) with ultrasound wave nanometer silver powder is made dispersion treatment;
3) add deionized water and make diluent;
4) in diluent, add Reducing agent and stabilizing agent and dispersant;
5) fill, sealing are preserved.
Wherein said Reducing agent generally uses sulphite, preferably uses sodium metabisulfite or sodium sulfite; Described stabilizing agent preferably uses V
E,, V
COr different V
CIn a kind of, or between them with any proportional quantity, the mixture that is arbitrarily made with; Described dispersant generally uses the high molecular polymer class, and surfactant-based and organic acid dispersant preferably uses triethanolamine.
Nano-silver water solution preparation of the present invention is particularly suitable for treating urethra, bladder disease and male venereal disease.
The using method of nano-silver water solution preparation of the present invention when being used for the treatment of urethra, bladder disease and male venereal disease is to inject bladder by urethra.
Because the present invention is a kind of aqueous solution preparation, therefore easily inject urethra and bladder, can be used for treating urethra and bladder inflammation, particularly treat male venereal disease.What the present invention was the most outstanding is also advantageous in that, all Reducing agents in the nano-silver water solution preparation of the present invention and stabilizing agent all are through U.S. FDA or ministry of Health of China approval, can be applied to the additive in food or the medicine, and use amount is limited the quantity of less than maximum, therefore human body is not had stimulation, life-time service can not cause untoward reaction such as poisoning.Safety testing shows this product avirulence, no anaphylaxis, to skin, mucosa nonirritant, and no sensitization, rapid-action, good effect has no side effect.Employed adjuvant or additive all can be buied from market among the present invention, also can adopt the conventional similar product that uses in the industry, therefore are convenient to large-scale industrialization production.
(4) specific embodiment:
Below further specify the present invention by specific embodiment, but embodiment only be used for the explanation, can not limit the scope of the invention.
Embodiment one
1) ratio takes by weighing nanometer silver 0.35 gram, triethanolamine 1 gram, sodium metabisulfite 0.12 gram, V
E1 gram, deionized water 1000 grams;
2) nanometer silver powder is made dispersion treatment with ultrasound wave;
3) add deionized water and make diluent;
4) in diluent, add sodium metabisulfite, triethanolamine and V
E
5) stir, fill, sealing are preserved.
The said goods is to killing effect such as the following table of various pathogenic bacterias:
As seen from the above table, product of the present invention can be killed multiple sexually transmitted disease (STD) pathogenic bacteria in 8～12 hours, be a kind of medicine of good treatment sexually transmitted disease (STD).
It is as follows that the said goods is used for the male venereal disease therapeutic effect:
Treat clinical std patient 38 examples, be the male, age between 25～53, wherein infection of staphylococcus aureus person 3 examples, charrin's disease person 5 examples, candida albicans infection person 4 examples, gonococcal infection person 7 examples, mycoplasma infection person's 9 examples, chlamydia infection person 5 examples, trichomonas vaginalis infection person 5 examples.
Therapeutic Method is to adopt the mode of this product being injected bladder from urethra.Inject a deuterzooid product every day, inject 40ml at every turn, treating six days is a course of treatment, treats two courses of treatment continuously, and cure rate is 95%.The cooperation antibiotic therapy of in particular cases can following the doctor's advice.
Embodiment two
1) takes by weighing nanometer silver 0.15 gram, triethanolamine 1 gram, sodium sulfite 0.05 gram, V
E, V
CWith different V
CEach 0.5 gram, deionized water 1000 grams;
2) nanometer silver powder is made dispersion treatment with ultrasound wave;
3) add deionized water and make diluent;
4) in diluent, add sodium sulfite, triethanolamine, V
E, and different V
C
5) stir, fill, sealing are preserved.
Claims (5)
1, a kind of nano-silver water solution preparation, the weight distribution ratio of its each composition is as follows: nanometer silver 0.05～1.5, dispersant 0.5～1.5, Reducing agent 0.05～0.2, stabilizing agent are 0.5～10, deionized water 1000; Wherein said Reducing agent is a sulphite; Described stabilizing agent is a kind of among VE, VC or the different VC, or the mixture of forming with any proportional quantity, combination in any mode between them; Described dispersant is a triethanolamine.
2, nano-silver water solution preparation according to claim 1 is characterized in that: described sulphite is sodium metabisulfite or sodium sulfite.
3, nano-silver water solution preparation according to claim 1 and 2 is characterized in that wherein the weight distribution ratio of each composition is as follows:
Nanometer silver 0.08～1.2, dispersant 0.8～1.2, Reducing agent 0.1～0.15, stabilizing agent 0.8～2, deionized water 1000.
4, nano-silver water solution preparation according to claim 3 is characterized in that wherein the weight distribution ratio of each composition is as follows:
Nanometer silver 0.35, dispersant 1, Reducing agent 0.12, stabilizing agent are 1, deionized water 1000.
5, control the application of the medicine of urethra, bladder disease and male venereal disease in preparation according to the described nano-silver water solution preparation of claim 1～4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410022463 CN1245152C (en) | 2004-04-30 | 2004-04-30 | Nano-silver aqueous solution preparation and its preparation method, use and using method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410022463 CN1245152C (en) | 2004-04-30 | 2004-04-30 | Nano-silver aqueous solution preparation and its preparation method, use and using method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1569366A CN1569366A (en) | 2005-01-26 |
| CN1245152C true CN1245152C (en) | 2006-03-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410022463 Expired - Fee Related CN1245152C (en) | 2004-04-30 | 2004-04-30 | Nano-silver aqueous solution preparation and its preparation method, use and using method |
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Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104473965A (en) * | 2005-08-04 | 2015-04-01 | 林成龙 | Composition containing silver nanoparticles and application thereof |
| US20090011046A1 (en) * | 2005-08-04 | 2009-01-08 | Chenlung Lin | Composition Comprising Silver Nanoparticles and the Use Thereof |
| CN100425375C (en) * | 2006-04-03 | 2008-10-15 | 庄平 | Nano-class silver colloidal solution and preparation method thereof |
| KR20180056811A (en) * | 2010-08-27 | 2018-05-29 | 도와 일렉트로닉스 가부시키가이샤 | Low-temperature sintered silver nanoparticle composition and electronic articles formed using the same |
| CN103862988B (en) * | 2014-03-21 | 2016-02-03 | 德华兔宝宝装饰新材股份有限公司 | A kind of Nano Silver decoration veneer of antimildew and antibacterial |
| CN103817348B (en) * | 2014-03-21 | 2015-12-02 | 德华兔宝宝装饰新材股份有限公司 | A kind of nano-silver water solution and the using method for Recombinant Wood thereof |
| CN103832205B (en) * | 2014-03-21 | 2016-03-30 | 德华兔宝宝装饰新材股份有限公司 | A kind of Nano Silver decoration veneer |
| CN103817753B (en) * | 2014-03-21 | 2015-11-25 | 德华兔宝宝装饰新材股份有限公司 | A kind of Nano Silver floor of antimildew and antibacterial |
| CN103817754B (en) * | 2014-03-21 | 2015-09-16 | 德华兔宝宝装饰新材股份有限公司 | A kind of Nano Silver floor |
| CN105640986A (en) * | 2014-11-28 | 2016-06-08 | 广东工业大学 | Silver nanoparticle composition for control of lung cancer and prostate cancer |
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- 2004-04-30 CN CN 200410022463 patent/CN1245152C/en not_active Expired - Fee Related
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| CN1569366A (en) | 2005-01-26 |
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Granted publication date: 20060315 |