CN1856499A - 用作趋化因子受体尤其是cx3cr1拮抗剂的新的2－取代的4－氨基－噻唑并[4,5－d]嘧啶 - Google Patents

用作趋化因子受体尤其是cx3cr1拮抗剂的新的2－取代的4－氨基－噻唑并[4,5－d]嘧啶 Download PDF

Info

Publication number
CN1856499A
CN1856499A CN 200480027529 CN200480027529A CN1856499A CN 1856499 A CN1856499 A CN 1856499A CN 200480027529 CN200480027529 CN 200480027529 CN 200480027529 A CN200480027529 A CN 200480027529A CN 1856499 A CN1856499 A CN 1856499A
Authority
CN
China
Prior art keywords
amino
compound
formula
thiazole
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 200480027529
Other languages
English (en)
Chinese (zh)
Inventor
冈纳·诺德瓦尔
托布拉斯·莱因
丹尼尔·索恩
罗纳德·泽姆里博
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1856499A publication Critical patent/CN1856499A/zh
Pending legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN 200480027529 2003-10-07 2004-10-05 用作趋化因子受体尤其是cx3cr1拮抗剂的新的2－取代的4－氨基－噻唑并[4,5－d]嘧啶 Pending CN1856499A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE03026663 2003-10-07
SE03026671 2003-10-07
SE0302666A SE0302666D0 (sv) 2003-10-07 2003-10-07 Novel Compounds

Publications (1)

Publication Number Publication Date
CN1856499A true CN1856499A (zh) 2006-11-01

Family

ID=29398688

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 200480027529 Pending CN1856499A (zh) 2003-10-07 2004-10-05 用作趋化因子受体尤其是cx3cr1拮抗剂的新的2－取代的4－氨基－噻唑并[4,5－d]嘧啶

Country Status (2)

Country Link
CN (1) CN1856499A (sv)
SE (1) SE0302666D0 (sv)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104195234A (zh) * 2014-07-29 2014-12-10 杭州艾迪康医学检验中心有限公司 检测cx3cr1基因v249i突变位点的方法和引物
CN105073727A (zh) * 2013-03-12 2015-11-18 卫材R&D管理有限公司 吡咯烷-3-基乙酸衍生物的盐及其晶体

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105073727A (zh) * 2013-03-12 2015-11-18 卫材R&D管理有限公司 吡咯烷-3-基乙酸衍生物的盐及其晶体
US9550732B2 (en) 2013-03-12 2017-01-24 Eisai R&D Management Co., Ltd. Salt of pyrrolidin-3-yl acetic acid derivative and crystals thereof
CN105073727B (zh) * 2013-03-12 2017-02-22 卫材R&D管理有限公司 吡咯烷‑3‑基乙酸衍生物的盐及其晶体
CN104195234A (zh) * 2014-07-29 2014-12-10 杭州艾迪康医学检验中心有限公司 检测cx3cr1基因v249i突变位点的方法和引物

Also Published As

Publication number Publication date
SE0302666D0 (sv) 2003-10-07

Similar Documents

Publication Publication Date Title
CN1298703C (zh) 氰基吡咯烷衍生物
CN1198825C (zh) 8－苯基－6,9－二氢－[1,2,4]三唑并[3,4－i]嘌呤－5－酮衍生物
CN1190437C (zh) 治疗牛皮癣的蝶啶类化合物
CN1150195C (zh) 双环氮杂环
CN1171889C (zh) 作为p38蛋白激酶的抑制剂的杂烷基氨基－取代的双环氮杂环类化合物
CN1434805A (zh) 选择性神经激肽拮抗剂
CN1649863A (zh) 具有cdk抑制活性的4－(咪唑－5－基)－2－(4－磺基苯胺基)嘧啶衍生物
CN1290846C (zh) 吡唑并[1,5－a]吡啶化合物及其药物
CN1549817A (zh) 作为半胱氨酸蛋白酶抑制剂的吡咯并嘧啶化合物
CN1649581A (zh) 取代的3－氨基－噻吩并[2,3－b]吡啶－2－羧酸酰胺化合物及其制备方法和用途
CN1114598C (zh) 芳族化合物和含有它们的药物组合物
CN1761671A (zh) 用作PDE7抑制剂的4－氨基噻吩并[2,3－d]嘧啶－6－甲腈衍生物
CN1764650A (zh) 2,3,6－三取代的－4－嘧啶酮衍生物
CN1761672A (zh) 噻吩并嘧啶二酮及其在调节自身免疫疾病中的用途
CN1993363A (zh) 1,3－二取代的杂芳基nmda/nr2b拮抗剂
CN1703405A (zh) 用作糖原合酶激酶3β抑制剂的氨基苯甲酰胺衍生物
AU2015210593A1 (en) Compounds
CN1849325A (zh) 可抑制蛋白激酶的噻唑并、噁唑并和咪唑并喹唑啉化合物
CN101035781A (zh) 2－吗啉基－4－嘧啶酮化合物
CN1993129A (zh) 用于药物的噻吩并嘧啶和噻唑并嘧啶
CN1898199A (zh) 用于治疗阿尔茨海默病的苯基酰胺和吡啶基酰胺类β－分泌酶抑制剂
CN101035795A (zh) 噻唑基二氢吲唑
CN1993360A (zh) 作为激酶抑制剂的缩合的吡啶类
CN1379777A (zh) 氨基－三唑并吡啶衍生物
CN101048397A (zh) 作为τ蛋白激酶1抑制剂的6－（吡啶基）－4－嘧啶酮衍生物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication